Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Wurfbainia villosum
Species name
Species info
Gene sequence info
Wurfbainia_villosum.HIDH.fa
Download
>Avi01G001305.t1
MASSDALSLPPPHVVDDCRGILRVLSDGTVLRSANTGFSVPVADDGSVEWKDVPFFPGPDALCLRLYRPRRAPGTRFPVFFYFHGGGFCIGSRTWPNCQNYCLRLASDLGAFVVAPDYRLAPEHRLPAAIDDSVAALEWLRSGDPWLSESADLGRVFISGDSAGGNIAHHLAFRFGSPAGRAALAPIRLRGFVLLMPFFGGSRRTRSEAECPDDAFLNRDLNDRYWRLSIPAGATLDHPLVNPFGPESPDLEAAELEPILVVVGERDLLRDRAAEYAARLKGWKMPVELAEFARQQHGFFTLDPRSEASDELMRRIKRFMEENQGYA
>Avi01G002062.t1
MASSDALSLPPPHVVDDCRGILRVLSDGTVLRSANTGFSVPVADDGSVEWKDVPFFPGPDALCLRLYRPRRAPGTRFPVFFYFHGGGFCIGSRTWPNCQNYCLRLASDLGAFVVAPDYRLAPEHRLPAAIDDSVAALEWLRSGDPWLSESADLGRVFISGDSAGGNIAHHLAFRFGSPAGRAALAPIRLRGFVLLMPFFGGSRRTRSEAECPDDAFLNRDLNDRYWRLSIPAGATLDHPLVNPFGPESPDLEAAELEPILVVVGERDLLRDRAAEYAARLKGWKMPVELAEFARQQHGFFTLDPRSEVSDELMRRIKRFMEENQGYA
>Avi12G001288.t1
MGASPCAQLRDDQINPQRQPVTGDDHGPATEEVRGLIRLYKDGHVERLPAVASVPSTLTMDSGVVCEELTVAGGLPARLYLLPDPKLQALPLLVYFHGGGFCVGSVAWGCYHEFAARLAARANCAVLSVDYRLAPEHPLPAAYEDGVAVLRWVTHRASGELARWRRLCDFSRVFLAGDSAGAAIAYHAALKHDAKSEAAAPLRGAILIQPFFGGAVRTWSETNLPQSSKSALSLATSDCYWRMALPAGADRDHRWCNPLTEKLPAEEASRRRLPALLVCDSELDILRDRSREFCKAMRGAGVRVDQVTMAGVGHAFQILHNYPSSHARTTEMLTYIRDFINDT
>Avi13G000317.t1
MRKRRLGAVPHHLIADLRINTNIQTSNNADHGAVLEEIEGLIKVYKDGYVERMPAVPHVPCTWASQPGVTSEDVALDGSSTDLWARLHMPAHRHQRFPLLVYFHGGGFCIGSPSWRCYHEFLARLAAHAACAVLSVNYRLAPEHRLPAALEDGVAALRWVRQQAAGSRCEDLGSWRARFDFGRVFLAGDSAGAVIAYHVAAAVGAEAAALLRPACLKGVILIQPFFCGVERTWSEKNLAQAAERSALSLAASDCYWRMALPPGANQDHPWCNPLAKGASPLEGLHLPPLLVCVSELDILRDRNLAFCKALRNAGKGVEHKTYAGVGHAFQILHNYQMWQVRTNEMLIHIKSFITNVR
>Avi19G001690.t1
MASFPSGHVEDDEVVYQVSQFLTIYKSGRVDRPLDAVIVPADTADPAGSADTVGVAFKDLVISSDTGHVSARLYLPKRAATQARKVPLLLYFHGGGFCIGNPFMRSFHDYVVSLVAQANVVAVSVDYRLAPEHPIPAAYDDAWTALRWGTAGPAADRWLADHADFGRVFLAGESAGANIAHNMAMRAAKEALLPGGVGLQGIVLVHPYLLGSNPLPSEKISPDMTAGLKRMWEIAYPTGAGDVDHPWINPLAAGAPSLSGLGCRRVLVCLAEEDVMRDRGREYFQRLRESGWEGESELYESPAKGHAFHLFDADSEQRLALDEAICNFLNR
>Avi19G001631.t1
MDPDAEIAYDYSPYLYLFKSGRVKRLDPPDLIPASANDSVVASRDVIVDSATGVSVRLFRPNNINANTKLPVLIYLHGGGFVIGSPFSYTYHHFVHALVARARVLAVSLGYRLAPEHPLPAAYDDALSAIRWVACHAGGSGPDSWLAEHGDLRRIFLAGDSAGANIAHNVLVQMGAGGLGGGARIEGVVLIHPYFWGKHPLDGETASVGQREWQESSWRFVSAGAIELEDPRADPSKEAANRLKAMPCRRALVVVAENDFYAARGRAYYETVRRSGWSGSVELYVTAGERHVFHLRTPESRKAVAMLKKISAFLHADKPLNKLTAKFQFTSKLLDFFRNAK
>Avi02G001532.t1
MAPLGGGNPVVDDFSPYFRVYKDGSVERLMSEERTPASLDPRTGVNSKDVRISPDVSGRVYLPPEAAEAAYRGGRKLPLVLYFRGGAFCMLSSASPILHAHLNALAAATSAVILSVDYRRAPEHHIPVPYDDSWAALEWAASHRAGVGRSISSAEPWLVEHADFDRVYLAGDSAGGNIAHNLGLRAASRQLPGGVKLAAIVLVDPYFWGTLPTASEGSADPAKLELLDRLWRLVCPSTEAGNDDPRVNPLVEGAPSLTGMACGRVLVCTAEKDAMRDRAWMYYEALRKSGWRGEAEMYETAAEDHGFYLYRPDGHGAAMLLKRIAAFLA
>Avi02G001531.t1
MGSLSAVAADANANPVVDDFSPYFRVYKDGSVERLREEEHTPASLDPRTGVDSKDIAISAFVSARIYLPPASASSGGDSGNKLPLVLYFRGGGFCVLSASSPVVHTHLNALAAASSVIVLSVDYRRAPEHSIPIPYDDSWAALHWAASHRAAGLEGIDFDFSPESWLVEHADFDRVYLAGDSAGGNIAHNLAMRAATLPLPGAVKLAGIVLLEPYFWGTRPTASAAAADPVKRALLDRLWRVVCPASEAGNDDPLVNPLAVRAPSLSVLGCGRVLVYTAERDAMRDWAWMYYEALRESRWRGEAEIFEAVGEDHGFYLHRPNGDCVALLLKRIAAFLA
>Avi02G003015.t1
MAAVAPADSADEIAVDAFPFVRIYKSGRIERFMGTSVVPAGVDSATGVVSKDVLVDPATKLSARLYLPGHPHPDRALPVLVYFHGGGFVIESAASPTYHNYLNALVAAAGVVAVSVEYRRAPECPLPVAYDDSFAALRWVASRPAEEPWLAEGRADLGRLFLAGDSAGANIVHHVALRAASEGLGRDEAAIVGLLLIHPFFWGSEPIGSEPKALPEREKVDQLWQLTCPGTNGADDPLINPAAEGASSLAALPARRVMVAVAEKDMLKDRGRAYHVLLSRSGWKGEALLEEAEGPDASHVFHLHNPACEISTNMLKTVAAFLNSVD
>Avi02G003014.t1
MAAAAPAESADEIAVDGFPFVRVYKSGRIERFLGTSVVPAGVDSATGVVSKDVVIDPATKLSARLYLPGHPHPDRALPVLLYFHGGGFVVESASSPTYHNYLNALVAAAGVVAVSVEYRLAPECPLPAAYDDCFAALRWVASRPAEEPWLAEGRADLGRLFLAGDSAGANIVHHVALRAAAEGLGRDEAAIVGLLLIHPFFWGSEPIGSEPKAPAEREKTGQLWQLACPGTNGADDPLINLAAEGASSLAALPARRVMVAVAEKDMFKDRGRAYHVLLSRSGWKGEARLEEAEGPDASHVFHLHNPACEISTNMLKTVAAFLNSVD
>Avi21G000084.t1
MKRRRIRMGAVSQQLTQLSISGGVKDDAAHGAVVEEINGLIRLYKDGHVERLPAVADVPCTWTPHPGVVSQDVSLAPSAALWARLHLPAHPLLQSRLPLPAHPLLQSRLPLLVYFHGGGFCVGSPAWRCYHEFLARLAAHAACAVLSVSYRLAPEHRLPAAFQDGLSALRWVRQQAAPSLREDSAGSWHARCDFGRVFLGGDSAGAAIAYHVAAAGGMDPVAPRPSFCLRGVVLIQPFVGGVERKWSEKNHQTPKSSALSPSTSDCYWRMALPAGADRDHPWCNPLSKKAPPVEDQRLPPLLVCISDLDILRDRNLELCKALRYSGQRVEEKTYADVGHAFQVLHNCPMSQNRTIDMLTDIKAFINTCLF
>Avi03G001086.t1
MLTSSPPPCPSDPTGVSFKGLVIFLDSGVPAPLYLPNRAAAKSEKVHLLVYFHGGGFCIGNPLHARLKRLRLYVISLVARANIAAVAVNYRLELEHSIPAACDDS
>Avi05G001538.t1
MDPDSEVVFDFPPFLRLYKNGSVHRLIGNDYIPAGIDPSTGVVSKDVLIDPHTVLSARLYLRRLSASTRRPIFVYCHGGAFVIESAFSPTYHTFLNNLVAQTDVVAVSIEYRRAPEHPLPAAYHDAFAVLRWVASHASGGGSGQTWLAERGDFGRLFLAGDSAGGNIAHNILVRARAEPLENEIKVAGLLLIHPFFWGKEAVGSEPTDPVFRQWLETTWGFVCGWSAGIEDPRVDPFRDEAALRELPCRRVLVSITERDWFRERGKEYYERLRASGWEGEAELVETAEEEHVYFLSEPKCDKALAEMARFVAFISRD
>Avi07G000122.t1
MDPDSEIVFDFPPFLRLYKSGRVHRLIGTDLVPAGVDPATGVASKDVHIDPRTGLSARLYVFCPTASTRRPILFYLHGGAFVAESAFSPTYHTFLNNVVARADVVAVSVEYRRAPEDPLPAAYDDAFAALRWVASGGGGEAWLTERGDLDRVFLAGDSAGANIAHNILVRTLAEPLEIEIAGLALIHMYFWGKEAVGAEPTDPAFREWMETTWGFVCGWSAGIEDPRVDPFRDEAALRALPCRRVLVSVTEKDLFRERGKAYYEKLRASGWEGEAELVETEGEEHVYFLSNPNCEKASAEVARLVAFLSHDS
MASSDALSLPPPHVVDDCRGILRVLSDGTVLRSANTGFSVPVADDGSVEWKDVPFFPGPDALCLRLYRPRRAPGTRFPVFFYFHGGGFCIGSRTWPNCQNYCLRLASDLGAFVVAPDYRLAPEHRLPAAIDDSVAALEWLRSGDPWLSESADLGRVFISGDSAGGNIAHHLAFRFGSPAGRAALAPIRLRGFVLLMPFFGGSRRTRSEAECPDDAFLNRDLNDRYWRLSIPAGATLDHPLVNPFGPESPDLEAAELEPILVVVGERDLLRDRAAEYAARLKGWKMPVELAEFARQQHGFFTLDPRSEASDELMRRIKRFMEENQGYA
>Avi01G002062.t1
MASSDALSLPPPHVVDDCRGILRVLSDGTVLRSANTGFSVPVADDGSVEWKDVPFFPGPDALCLRLYRPRRAPGTRFPVFFYFHGGGFCIGSRTWPNCQNYCLRLASDLGAFVVAPDYRLAPEHRLPAAIDDSVAALEWLRSGDPWLSESADLGRVFISGDSAGGNIAHHLAFRFGSPAGRAALAPIRLRGFVLLMPFFGGSRRTRSEAECPDDAFLNRDLNDRYWRLSIPAGATLDHPLVNPFGPESPDLEAAELEPILVVVGERDLLRDRAAEYAARLKGWKMPVELAEFARQQHGFFTLDPRSEVSDELMRRIKRFMEENQGYA
>Avi12G001288.t1
MGASPCAQLRDDQINPQRQPVTGDDHGPATEEVRGLIRLYKDGHVERLPAVASVPSTLTMDSGVVCEELTVAGGLPARLYLLPDPKLQALPLLVYFHGGGFCVGSVAWGCYHEFAARLAARANCAVLSVDYRLAPEHPLPAAYEDGVAVLRWVTHRASGELARWRRLCDFSRVFLAGDSAGAAIAYHAALKHDAKSEAAAPLRGAILIQPFFGGAVRTWSETNLPQSSKSALSLATSDCYWRMALPAGADRDHRWCNPLTEKLPAEEASRRRLPALLVCDSELDILRDRSREFCKAMRGAGVRVDQVTMAGVGHAFQILHNYPSSHARTTEMLTYIRDFINDT
>Avi13G000317.t1
MRKRRLGAVPHHLIADLRINTNIQTSNNADHGAVLEEIEGLIKVYKDGYVERMPAVPHVPCTWASQPGVTSEDVALDGSSTDLWARLHMPAHRHQRFPLLVYFHGGGFCIGSPSWRCYHEFLARLAAHAACAVLSVNYRLAPEHRLPAALEDGVAALRWVRQQAAGSRCEDLGSWRARFDFGRVFLAGDSAGAVIAYHVAAAVGAEAAALLRPACLKGVILIQPFFCGVERTWSEKNLAQAAERSALSLAASDCYWRMALPPGANQDHPWCNPLAKGASPLEGLHLPPLLVCVSELDILRDRNLAFCKALRNAGKGVEHKTYAGVGHAFQILHNYQMWQVRTNEMLIHIKSFITNVR
>Avi19G001690.t1
MASFPSGHVEDDEVVYQVSQFLTIYKSGRVDRPLDAVIVPADTADPAGSADTVGVAFKDLVISSDTGHVSARLYLPKRAATQARKVPLLLYFHGGGFCIGNPFMRSFHDYVVSLVAQANVVAVSVDYRLAPEHPIPAAYDDAWTALRWGTAGPAADRWLADHADFGRVFLAGESAGANIAHNMAMRAAKEALLPGGVGLQGIVLVHPYLLGSNPLPSEKISPDMTAGLKRMWEIAYPTGAGDVDHPWINPLAAGAPSLSGLGCRRVLVCLAEEDVMRDRGREYFQRLRESGWEGESELYESPAKGHAFHLFDADSEQRLALDEAICNFLNR
>Avi19G001631.t1
MDPDAEIAYDYSPYLYLFKSGRVKRLDPPDLIPASANDSVVASRDVIVDSATGVSVRLFRPNNINANTKLPVLIYLHGGGFVIGSPFSYTYHHFVHALVARARVLAVSLGYRLAPEHPLPAAYDDALSAIRWVACHAGGSGPDSWLAEHGDLRRIFLAGDSAGANIAHNVLVQMGAGGLGGGARIEGVVLIHPYFWGKHPLDGETASVGQREWQESSWRFVSAGAIELEDPRADPSKEAANRLKAMPCRRALVVVAENDFYAARGRAYYETVRRSGWSGSVELYVTAGERHVFHLRTPESRKAVAMLKKISAFLHADKPLNKLTAKFQFTSKLLDFFRNAK
>Avi02G001532.t1
MAPLGGGNPVVDDFSPYFRVYKDGSVERLMSEERTPASLDPRTGVNSKDVRISPDVSGRVYLPPEAAEAAYRGGRKLPLVLYFRGGAFCMLSSASPILHAHLNALAAATSAVILSVDYRRAPEHHIPVPYDDSWAALEWAASHRAGVGRSISSAEPWLVEHADFDRVYLAGDSAGGNIAHNLGLRAASRQLPGGVKLAAIVLVDPYFWGTLPTASEGSADPAKLELLDRLWRLVCPSTEAGNDDPRVNPLVEGAPSLTGMACGRVLVCTAEKDAMRDRAWMYYEALRKSGWRGEAEMYETAAEDHGFYLYRPDGHGAAMLLKRIAAFLA
>Avi02G001531.t1
MGSLSAVAADANANPVVDDFSPYFRVYKDGSVERLREEEHTPASLDPRTGVDSKDIAISAFVSARIYLPPASASSGGDSGNKLPLVLYFRGGGFCVLSASSPVVHTHLNALAAASSVIVLSVDYRRAPEHSIPIPYDDSWAALHWAASHRAAGLEGIDFDFSPESWLVEHADFDRVYLAGDSAGGNIAHNLAMRAATLPLPGAVKLAGIVLLEPYFWGTRPTASAAAADPVKRALLDRLWRVVCPASEAGNDDPLVNPLAVRAPSLSVLGCGRVLVYTAERDAMRDWAWMYYEALRESRWRGEAEIFEAVGEDHGFYLHRPNGDCVALLLKRIAAFLA
>Avi02G003015.t1
MAAVAPADSADEIAVDAFPFVRIYKSGRIERFMGTSVVPAGVDSATGVVSKDVLVDPATKLSARLYLPGHPHPDRALPVLVYFHGGGFVIESAASPTYHNYLNALVAAAGVVAVSVEYRRAPECPLPVAYDDSFAALRWVASRPAEEPWLAEGRADLGRLFLAGDSAGANIVHHVALRAASEGLGRDEAAIVGLLLIHPFFWGSEPIGSEPKALPEREKVDQLWQLTCPGTNGADDPLINPAAEGASSLAALPARRVMVAVAEKDMLKDRGRAYHVLLSRSGWKGEALLEEAEGPDASHVFHLHNPACEISTNMLKTVAAFLNSVD
>Avi02G003014.t1
MAAAAPAESADEIAVDGFPFVRVYKSGRIERFLGTSVVPAGVDSATGVVSKDVVIDPATKLSARLYLPGHPHPDRALPVLLYFHGGGFVVESASSPTYHNYLNALVAAAGVVAVSVEYRLAPECPLPAAYDDCFAALRWVASRPAEEPWLAEGRADLGRLFLAGDSAGANIVHHVALRAAAEGLGRDEAAIVGLLLIHPFFWGSEPIGSEPKAPAEREKTGQLWQLACPGTNGADDPLINLAAEGASSLAALPARRVMVAVAEKDMFKDRGRAYHVLLSRSGWKGEARLEEAEGPDASHVFHLHNPACEISTNMLKTVAAFLNSVD
>Avi21G000084.t1
MKRRRIRMGAVSQQLTQLSISGGVKDDAAHGAVVEEINGLIRLYKDGHVERLPAVADVPCTWTPHPGVVSQDVSLAPSAALWARLHLPAHPLLQSRLPLPAHPLLQSRLPLLVYFHGGGFCVGSPAWRCYHEFLARLAAHAACAVLSVSYRLAPEHRLPAAFQDGLSALRWVRQQAAPSLREDSAGSWHARCDFGRVFLGGDSAGAAIAYHVAAAGGMDPVAPRPSFCLRGVVLIQPFVGGVERKWSEKNHQTPKSSALSPSTSDCYWRMALPAGADRDHPWCNPLSKKAPPVEDQRLPPLLVCISDLDILRDRNLELCKALRYSGQRVEEKTYADVGHAFQVLHNCPMSQNRTIDMLTDIKAFINTCLF
>Avi03G001086.t1
MLTSSPPPCPSDPTGVSFKGLVIFLDSGVPAPLYLPNRAAAKSEKVHLLVYFHGGGFCIGNPLHARLKRLRLYVISLVARANIAAVAVNYRLELEHSIPAACDDS
>Avi05G001538.t1
MDPDSEVVFDFPPFLRLYKNGSVHRLIGNDYIPAGIDPSTGVVSKDVLIDPHTVLSARLYLRRLSASTRRPIFVYCHGGAFVIESAFSPTYHTFLNNLVAQTDVVAVSIEYRRAPEHPLPAAYHDAFAVLRWVASHASGGGSGQTWLAERGDFGRLFLAGDSAGGNIAHNILVRARAEPLENEIKVAGLLLIHPFFWGKEAVGSEPTDPVFRQWLETTWGFVCGWSAGIEDPRVDPFRDEAALRELPCRRVLVSITERDWFRERGKEYYERLRASGWEGEAELVETAEEEHVYFLSEPKCDKALAEMARFVAFISRD
>Avi07G000122.t1
MDPDSEIVFDFPPFLRLYKSGRVHRLIGTDLVPAGVDPATGVASKDVHIDPRTGLSARLYVFCPTASTRRPILFYLHGGAFVAESAFSPTYHTFLNNVVARADVVAVSVEYRRAPEDPLPAAYDDAFAALRWVASGGGGEAWLTERGDLDRVFLAGDSAGANIAHNILVRTLAEPLEIEIAGLALIHMYFWGKEAVGAEPTDPAFREWMETTWGFVCGWSAGIEDPRVDPFRDEAALRALPCRRVLVSVTEKDLFRERGKAYYEKLRASGWEGEAELVETEGEEHVYFLSNPNCEKASAEVARLVAFLSHDS
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University