Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Wurfbainia villosum
Species name
Species info
Gene sequence info
Wurfbainia_villosum.4CL.fa
Download
>Avi01G000181.t1
MGSHLVPEEIIFRSKLPDIAIDNCRPLHTYCFERLADLGDRPCLIDGASGTVMSYAEVDLASRRVASGLRRIGVGRREVIMILLQNSPEFVLAFLGASHHGAVPTTANPFYTPAEIHKQAADAGARVIVTESRYVDKVREFARERGVVIVCVDDPLPEGCRSFSELMKEEEETEEEIDADEVVALLYSSGTTGLPKGVMLTHRSLITSVAQQVDGDNPNLYFRKEDVLLCVLPLFHIYSLNSVLLCGLRVGAAILLMRRFEISTMLELVQRYRVTVAPFVPPIVLEFVKSSLVDSYDLSSIRIVMSGAAPMGKELEDKFMAKLPNATLGQGYGMTEAGPVVAMCLAFAREPFPVKSGACGTVVRNAELKIVDPDTGLALGRNQRGEICIRGEQIMKGYLNDPEATKNTIDKEGWLHTGDIGLVDDDDEIFIVDRLKEIIKYKGFQVAPAELEALLTTHPDIADAGVVPMKDEAAGEIPVAFVVRSNGSRITDDEIKQYVSKQVIFYKRIGKVFFVEAIPKAPSGKILRKDLRARLSSPFS
>Avi16G000134.t2
MGSIAVEEETIFRSKLPDIEIKNDIPLHAYCFERLSEFADRPCIMDGASGDVLTYAQVDAAARRFAAGLLRAGVGRGDVFMILLRNSPEFVIAFLAASHAGAVATTANPFYTPGEIHKQAAAAGARLIVTESCYVEKIREFAEERRVAIVTVDDDGGVGCRRFSELLAADAGELAAVDIDPDDVVALPYSSGTTGLPKGVMLTHRSLITSVAQQVDGDNPNLYFHEDDVLLCVLPLFHIYSLNSVLLCGLRVGAAILIMRRFEVAPLLDLVQRYRVTVAPVVPPIVLELAKSPLMDGYDLSSIRMVMSGAAPMGKELEEKFMAKLPNARLGQGYGMTEAGPVLSMCLAFAKEPFEVKSGACGTVVRNAEMKIVDPDTGASLGRNQRGEICIRGSQIMKGYINDAEATNNTIDKDGWLHTGDIGYVDDDDEVFIVDRLKEIIKYKGFQVAPAELEALLVAHPNIADAAVVQMKDEAAGEVPVAFVVRSNGSHIAEDEIKQYISKQVVFYKRINKVCFTDAIPKAPSGKILRKDLRAKLAVLFP
>Avi18G000132.t1
MTIASSGYGPDGVYRSLQRPIALPEDPTLSMVPFLFRGAAAFPDRLAVADADSGDTLSFSELRSAVLSAASGLASACGVRKGDVVLIFAPNSLHYPVAFLAILSLGAVVTTVNPAYTIQELSKQASDACAKLVVTVTDLWPKAAALHLPAVIIGPKGFTSSLSSVSPFTYFSDLMSHPIPSGFSLPSVYQSDVAALLYSSGTTGASKGVVLTHRNFICTALMVTANQDARGEGPNTFLCFLPMFHIFGLSLITYAQLQRGNTIVSMPRFEMEATLKALEKYRVTYFFCVPPVMIALAKRGKMTKYDLSSLKFVGSGAAPLGKDVMEDVSKNLPNAIIIQGYGMTETCGFISLEEPTKGEVRKYGSTGNLAPHMEAKVVNVDTSKLLPANEVGELCFRGPNIMKEYHNNPQATNLTLREGWLHSGDLGYFDETGQLFVVDRIKELIKYKGFQVAPAELEGLLLSHPEILDSVVIPFPDAEAGEVPIAYVVRSANSSLTEVDVQDFIANQVAPYKRLRRVTFVTSVPKSASGKILRRELIQKVRSNL
>Avi23G001340.t1
MHLPSLRGFFREESEPQADALFSLVVTLLIDMAPLPEETIFRSKLPDIDIDNRRPLHAFCFERLAEFSDQPCLIDGSSGAIMSYAEVDSASRRAAAGLHRFGVGRGQVIMILLRNSPEFVLTFLGASRRGAVATTANPFYTPAEIHKQAAASGARVIVTESCFVDKVRDFARERGVVVVCVDDPLPEGCRRFSELLEEEEKTEEEEEEEEGIDPDDMVALPYSSGTTGLPKGVMLTHRSLITSVAQQVDGENPNLYFRSDDVLLCVLPLFHIYSLNSVLLCGLRAGAAILLVRKFEISAVLELVQRFRVTVAPFVPPIVLEFVKSSLVDAYDLSSIRIVKSGAAPMGKELEDKFMAKLPNATLGQGYGMTEAGPVLSMSLAFAKEPFPVKSGACGTVVRNAELKIVDPDTGVALARNQRGEICIRGEQIMKGYLNDPEATRNTIDKEGWLHTGDVGFVDDDDEIFIVDRLKELIKYKGFQVAPAELEALLIAHPNVADAAVVPMKDEAAGEIPVAFVVQSNGSQTTEEELKQYISKQVIFYKRIGKVFFVETIPKAPTGKILRKDLKAKLTSPF
>Avi24G001007.t1
MISVASHESEPLVDVAAAIQTPETVIFRSRLPDIELPNYLPVHTYCFQRLSEFADFACLISANDGKVYSFAETHRLCRKAAAGLTKVGVRKGDVIMLLLHNSPEFIFTFMGVSMLGAAATTANPYSTPSEIYKQIKAAGAKLVVTQSVYVDKLRNEEMFPRVGEGLTVVTTDEVAPAGCTSFWEVVGSAEEIEDEAEVEAEELMALPFSSGTTGLPKGVMLTHKSLVSSIAQQVDGENPNVHLKPGEDVVLCVLPLFHIFALNSVLLCALRSGAATVLMPKFEMGVMLQVIERHRVSMAAVVPPLVMALAKNPEVEKYDLSSIRFIISGAAPLGKELEDALRNRVPQAILGQGYGMTEAGPVLSMCSAFAKHPTPVKSGSCGTVVRNAEMKVVDPDTGFSLGRNKPGEICIRGPQIMKGYLNDVDATSKTIDVEGWMHTGDIGYIDDDDEVFIVDRVKELIKVKGFQVPPAELESLLLNHPEIVDAAVVPQKDAAAGEVPVAFVVRAIDSDIEEEAIKEFIAKQVVFYKRLQRIYFVHSIPKSAAGKIMRKELRAKLANAS
>Avi06G000995.t4
MGSLPEETIFRSKLPDIVIDNHRPLHAYCFERLPEFGDRPCLIDASGGAFMSYSEVDRMARLAAAGLRRLGLGRGQVIMILLRNSPEFVLAFLGASRCGAVATTANPFYTRAEIHKQAAAAGARVIVTESCYVDKVWDFARERGIIIVCVDDPLPEGCRRFSELLEAEEKTKEAEEDEIVDPDDVVALPYSSGTTGLPKGVMLTHRSLITSVAQQVDGENPNLYFHPDDVLLCVLPLFHIYSLNSVLLCGLRAGAAILLVRKFEISAVLELVQRYRVTVAPFVPPIVLEFVKSPLVDAYDLSSIRIVMSGAAPMGKELEDKFMTKLPNATLGQVTNRSPSSIIDSSVQISCFTHAPQFNNEQGYGMTEAGPVLSMCLAFAKEPLPVKSGACGTVVRNAELKIVDPDTGAALARNQCGEICIRGEQIMKGYLNDPEATRNTIDKEGWLHTGDIGFVDDDDEVFIVDRLKEIIKYKGFQVAPAELEALLVAHPDIVDAAVVPMRDEAAGEIPVAFAVRSSGSQITEDEVKHYVSKQVIFYKRIGKVFFVEAIPKAPSGKILRKDLRAKLASPIQTL
>Avi06G001354.t1
MGSIAPPEETIFRSKLPDIEITNGIPLHAYCFERLGEFADRPCIIDGATGAVFTYSEVEASARRFAAGLHSVGIRRGDVFMILLRNSPEFVIAFLAASFGGALATTANPFYTPGEIHKQAEGAGARLIITDSCYVDKIRHFAEERGVTIVTVGDYPATEGCRAFTDLLAVDACALPAVEFDPDDVVTLPYSSGTTGLPKGVMLTHRSLITSVAQQVDGENPNLYYHPEDVLLCVLPLFHIYSLHTVLLCGLRVGASILIMRRFEVGQLLELIQRFRVTIAPFVPPIVLEFVKSPLVDSYDLSSIRIVMSGAAPMGKELEDKFMAKLPNARLGQGYGMTEAGPVLSMCLAFAKAPFEVKSGACGTVVRNAEMKIVDPETGAVLGRNQRGEICIRGAQIMKGYINDPEATRNTIDKDGWLRTGDVGYVDDDDEVFIVDRLKEIIKYKGFQVAPAELEALLVTHPNICEAAVVPMKDEAAGEVPVAFVVRSNGSKITEDEIKQYISRQVIFYKRINKVFFIEAIPKAPSGKILRKDLRAKLAEQFPIGPFP
>Avi08G001506.t1
MGSIARPEETIFRSKLPDIEINNDISLHAYCFKRLEEFADRPCVIDGSTGTVLTYAQVEASARRFAAGLHSVGIGRGDVFMILLRNSVEFVIAFLAASFRGAVATTANPFYTPGEIHKQADGSGARLILTESCYVDKIRDYAADRGVTIIAVGDGPVPDGCHAFVDLLAPDVGALPAVVFDPDDVVALPYSSGTTGLPKGVMLTHRSLVTSVAQQVDGENPNLNFRPDDVLLCVLPLFHIYSLNSVLLCSLRVGAAILIMRRFEVGPLLELIQRFKVTIAPLVPPIVLEFIKSPLVDSYDLSSIRMVMSGAAPMGKEVEEKFMAKLPNARLGQGYGMTEAGPVLSMCLAFAKNPFEVKSGACGTVVRNAEMKIVDPETGAALARNQRGEICIRGAQIMKGYINDPEATRNTIDKDGWLHTGDVGYVDDDDEVFIVDRLKEIIKYKGFQVAPAELEALLVTHPKITDAAVVPMKDEVAGEVPVAFVVRSNGSKITEDEIKQYISRQVVFYKRISKVFFTEVIPKAPSGKILRKDLRAKLAEQFAIGPFP
MGSHLVPEEIIFRSKLPDIAIDNCRPLHTYCFERLADLGDRPCLIDGASGTVMSYAEVDLASRRVASGLRRIGVGRREVIMILLQNSPEFVLAFLGASHHGAVPTTANPFYTPAEIHKQAADAGARVIVTESRYVDKVREFARERGVVIVCVDDPLPEGCRSFSELMKEEEETEEEIDADEVVALLYSSGTTGLPKGVMLTHRSLITSVAQQVDGDNPNLYFRKEDVLLCVLPLFHIYSLNSVLLCGLRVGAAILLMRRFEISTMLELVQRYRVTVAPFVPPIVLEFVKSSLVDSYDLSSIRIVMSGAAPMGKELEDKFMAKLPNATLGQGYGMTEAGPVVAMCLAFAREPFPVKSGACGTVVRNAELKIVDPDTGLALGRNQRGEICIRGEQIMKGYLNDPEATKNTIDKEGWLHTGDIGLVDDDDEIFIVDRLKEIIKYKGFQVAPAELEALLTTHPDIADAGVVPMKDEAAGEIPVAFVVRSNGSRITDDEIKQYVSKQVIFYKRIGKVFFVEAIPKAPSGKILRKDLRARLSSPFS
>Avi16G000134.t2
MGSIAVEEETIFRSKLPDIEIKNDIPLHAYCFERLSEFADRPCIMDGASGDVLTYAQVDAAARRFAAGLLRAGVGRGDVFMILLRNSPEFVIAFLAASHAGAVATTANPFYTPGEIHKQAAAAGARLIVTESCYVEKIREFAEERRVAIVTVDDDGGVGCRRFSELLAADAGELAAVDIDPDDVVALPYSSGTTGLPKGVMLTHRSLITSVAQQVDGDNPNLYFHEDDVLLCVLPLFHIYSLNSVLLCGLRVGAAILIMRRFEVAPLLDLVQRYRVTVAPVVPPIVLELAKSPLMDGYDLSSIRMVMSGAAPMGKELEEKFMAKLPNARLGQGYGMTEAGPVLSMCLAFAKEPFEVKSGACGTVVRNAEMKIVDPDTGASLGRNQRGEICIRGSQIMKGYINDAEATNNTIDKDGWLHTGDIGYVDDDDEVFIVDRLKEIIKYKGFQVAPAELEALLVAHPNIADAAVVQMKDEAAGEVPVAFVVRSNGSHIAEDEIKQYISKQVVFYKRINKVCFTDAIPKAPSGKILRKDLRAKLAVLFP
>Avi18G000132.t1
MTIASSGYGPDGVYRSLQRPIALPEDPTLSMVPFLFRGAAAFPDRLAVADADSGDTLSFSELRSAVLSAASGLASACGVRKGDVVLIFAPNSLHYPVAFLAILSLGAVVTTVNPAYTIQELSKQASDACAKLVVTVTDLWPKAAALHLPAVIIGPKGFTSSLSSVSPFTYFSDLMSHPIPSGFSLPSVYQSDVAALLYSSGTTGASKGVVLTHRNFICTALMVTANQDARGEGPNTFLCFLPMFHIFGLSLITYAQLQRGNTIVSMPRFEMEATLKALEKYRVTYFFCVPPVMIALAKRGKMTKYDLSSLKFVGSGAAPLGKDVMEDVSKNLPNAIIIQGYGMTETCGFISLEEPTKGEVRKYGSTGNLAPHMEAKVVNVDTSKLLPANEVGELCFRGPNIMKEYHNNPQATNLTLREGWLHSGDLGYFDETGQLFVVDRIKELIKYKGFQVAPAELEGLLLSHPEILDSVVIPFPDAEAGEVPIAYVVRSANSSLTEVDVQDFIANQVAPYKRLRRVTFVTSVPKSASGKILRRELIQKVRSNL
>Avi23G001340.t1
MHLPSLRGFFREESEPQADALFSLVVTLLIDMAPLPEETIFRSKLPDIDIDNRRPLHAFCFERLAEFSDQPCLIDGSSGAIMSYAEVDSASRRAAAGLHRFGVGRGQVIMILLRNSPEFVLTFLGASRRGAVATTANPFYTPAEIHKQAAASGARVIVTESCFVDKVRDFARERGVVVVCVDDPLPEGCRRFSELLEEEEKTEEEEEEEEGIDPDDMVALPYSSGTTGLPKGVMLTHRSLITSVAQQVDGENPNLYFRSDDVLLCVLPLFHIYSLNSVLLCGLRAGAAILLVRKFEISAVLELVQRFRVTVAPFVPPIVLEFVKSSLVDAYDLSSIRIVKSGAAPMGKELEDKFMAKLPNATLGQGYGMTEAGPVLSMSLAFAKEPFPVKSGACGTVVRNAELKIVDPDTGVALARNQRGEICIRGEQIMKGYLNDPEATRNTIDKEGWLHTGDVGFVDDDDEIFIVDRLKELIKYKGFQVAPAELEALLIAHPNVADAAVVPMKDEAAGEIPVAFVVQSNGSQTTEEELKQYISKQVIFYKRIGKVFFVETIPKAPTGKILRKDLKAKLTSPF
>Avi24G001007.t1
MISVASHESEPLVDVAAAIQTPETVIFRSRLPDIELPNYLPVHTYCFQRLSEFADFACLISANDGKVYSFAETHRLCRKAAAGLTKVGVRKGDVIMLLLHNSPEFIFTFMGVSMLGAAATTANPYSTPSEIYKQIKAAGAKLVVTQSVYVDKLRNEEMFPRVGEGLTVVTTDEVAPAGCTSFWEVVGSAEEIEDEAEVEAEELMALPFSSGTTGLPKGVMLTHKSLVSSIAQQVDGENPNVHLKPGEDVVLCVLPLFHIFALNSVLLCALRSGAATVLMPKFEMGVMLQVIERHRVSMAAVVPPLVMALAKNPEVEKYDLSSIRFIISGAAPLGKELEDALRNRVPQAILGQGYGMTEAGPVLSMCSAFAKHPTPVKSGSCGTVVRNAEMKVVDPDTGFSLGRNKPGEICIRGPQIMKGYLNDVDATSKTIDVEGWMHTGDIGYIDDDDEVFIVDRVKELIKVKGFQVPPAELESLLLNHPEIVDAAVVPQKDAAAGEVPVAFVVRAIDSDIEEEAIKEFIAKQVVFYKRLQRIYFVHSIPKSAAGKIMRKELRAKLANAS
>Avi06G000995.t4
MGSLPEETIFRSKLPDIVIDNHRPLHAYCFERLPEFGDRPCLIDASGGAFMSYSEVDRMARLAAAGLRRLGLGRGQVIMILLRNSPEFVLAFLGASRCGAVATTANPFYTRAEIHKQAAAAGARVIVTESCYVDKVWDFARERGIIIVCVDDPLPEGCRRFSELLEAEEKTKEAEEDEIVDPDDVVALPYSSGTTGLPKGVMLTHRSLITSVAQQVDGENPNLYFHPDDVLLCVLPLFHIYSLNSVLLCGLRAGAAILLVRKFEISAVLELVQRYRVTVAPFVPPIVLEFVKSPLVDAYDLSSIRIVMSGAAPMGKELEDKFMTKLPNATLGQVTNRSPSSIIDSSVQISCFTHAPQFNNEQGYGMTEAGPVLSMCLAFAKEPLPVKSGACGTVVRNAELKIVDPDTGAALARNQCGEICIRGEQIMKGYLNDPEATRNTIDKEGWLHTGDIGFVDDDDEVFIVDRLKEIIKYKGFQVAPAELEALLVAHPDIVDAAVVPMRDEAAGEIPVAFAVRSSGSQITEDEVKHYVSKQVIFYKRIGKVFFVEAIPKAPSGKILRKDLRAKLASPIQTL
>Avi06G001354.t1
MGSIAPPEETIFRSKLPDIEITNGIPLHAYCFERLGEFADRPCIIDGATGAVFTYSEVEASARRFAAGLHSVGIRRGDVFMILLRNSPEFVIAFLAASFGGALATTANPFYTPGEIHKQAEGAGARLIITDSCYVDKIRHFAEERGVTIVTVGDYPATEGCRAFTDLLAVDACALPAVEFDPDDVVTLPYSSGTTGLPKGVMLTHRSLITSVAQQVDGENPNLYYHPEDVLLCVLPLFHIYSLHTVLLCGLRVGASILIMRRFEVGQLLELIQRFRVTIAPFVPPIVLEFVKSPLVDSYDLSSIRIVMSGAAPMGKELEDKFMAKLPNARLGQGYGMTEAGPVLSMCLAFAKAPFEVKSGACGTVVRNAEMKIVDPETGAVLGRNQRGEICIRGAQIMKGYINDPEATRNTIDKDGWLRTGDVGYVDDDDEVFIVDRLKEIIKYKGFQVAPAELEALLVTHPNICEAAVVPMKDEAAGEVPVAFVVRSNGSKITEDEIKQYISRQVIFYKRINKVFFIEAIPKAPSGKILRKDLRAKLAEQFPIGPFP
>Avi08G001506.t1
MGSIARPEETIFRSKLPDIEINNDISLHAYCFKRLEEFADRPCVIDGSTGTVLTYAQVEASARRFAAGLHSVGIGRGDVFMILLRNSVEFVIAFLAASFRGAVATTANPFYTPGEIHKQADGSGARLILTESCYVDKIRDYAADRGVTIIAVGDGPVPDGCHAFVDLLAPDVGALPAVVFDPDDVVALPYSSGTTGLPKGVMLTHRSLVTSVAQQVDGENPNLNFRPDDVLLCVLPLFHIYSLNSVLLCSLRVGAAILIMRRFEVGPLLELIQRFKVTIAPLVPPIVLEFIKSPLVDSYDLSSIRMVMSGAAPMGKEVEEKFMAKLPNARLGQGYGMTEAGPVLSMCLAFAKNPFEVKSGACGTVVRNAEMKIVDPETGAALARNQRGEICIRGAQIMKGYINDPEATRNTIDKDGWLHTGDVGYVDDDDEVFIVDRLKEIIKYKGFQVAPAELEALLVTHPKITDAAVVPMKDEVAGEVPVAFVVRSNGSKITEDEIKQYISRQVVFYKRISKVFFTEVIPKAPSGKILRKDLRAKLAEQFAIGPFP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University