Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Vigna radiata
Species name
Mung bean (Vigna radiata) is a species of eudicot in the family Fabaceae (pea family).
Species info
Gene sequence info
Vigna_radiata.COMT.fa
Download
>rna-XM_014642055.2
MELCFSEKDTETTLRAMVLGSNVVFPAALNAAIELNVFDIIAKEGSAESGGFMSPPEIASKLLIPRQQQHHRDLANRLERLLRLLASYSLLTVSSRSDGDGGSVRVYGVSESGKYFVRDENGDGYLASFTSFLCHPALSGVWLNFKEVVIDPEIDLFKKVHGMSKFEYFGKYPEINHVFNTAMHDICTTHMKKILEVYTGYEGISTLVDVGGGIGQCLKIIISKYPSIKGINFDLPHVIENSSPIPGVEHVGGNMFEGVPQGDAIMLKAITHNWSDEKVIELLSNCHKALPPKGKVIVGDFILPEDPEPTNEHKMISILDNIMFITPGGRERTEKEFDSLGKSSGFSRFEVVCRAFSTMAVMEFYK
>rna-XM_014643619.2
MTSLPNSRLNGEEKKKEAEEREDEESFSRAMQLVSSXVLPMAVQSATELGVFEVLKEAGEGAKLSAKDIXSKISCTNPEAASMLDRLLXLLSSHSILHSXLXSDNLVPPTFHRLYSITPLATFFARNSDGVSLGPLMAVTLDKIFLHSWSELKNAIREGGIPFNRVYGTHAFEYPRLDSRFNKVFNTGMINHTTLVMKRVLESYKGFDGIKSLVDVGGGLGINIKMITSKYPHIHGINFDLPHVIQDAPSYPGVDHVCGDMFENVPKGDAIFLKWILHDWSDEQCVKLLKNCYDAIPDDGKVIVMEAVLPTTPETNSAVYKAILELDVSMMTQNPGGKERCEQEFMDLATAAGFSGIRYECRANIFSVMEFFK
>rna-XM_014643970.1
MGSNCEEIDGEENDPCLSALLLSFSPMVYTAVLNASIELNLFEIIAKATKTTTPLGVSASEIASQLPIQHKKLPQRLDRMLSVLASHSLLTCSTLTNQDGKVQRLFQLSPSGKYFTNAEATASLALFTTFMNHPKLVQAFLNFKEIVLDCDKGLYMKVHGMPIFEGIQSDPTWNHIFNEAMANICRIEMTKILEIYSGFEGISLLIDVGGGVGQSLNIIISKYPSIKGVNFDLPQVIKQAPPYPGIEHVEGDMFESVPKGDAILLKGILHNWSDENCLKVLNNCYKALPENGKVVVVDFIMPEAIGSSEADKMVASFDNLMFLDGGSERTEKEFMNLCQISAFSSFRVVSRAFTALGVMEFYKN
>rna-XM_014643622.2
MENLPNSKLNGEEKKKEAEEREDEESFSRAMQLVSSXVLPMAVQSATELGVFEVLKEAGEGAKLSAKDIXSKISCTNPEAASMLDRLLXLLSSHSILHSSLVSDNLVPPTFHRLYSITPLATFFARNSDGVSLGPLMALLQDKIFLHSWTELKDAIREGGIPFNRAYGTHAFEYPRLDSRFNNVFNTAMINHTTLVMKRVLESYKGFEGIKRLVDVGGGLGINISLITSKYPHIHGINFDLPHVIQDAPSYPGVEHVGGDMFENVPKGDATFMKWILHDWSDEQCVKLLKNCYDAIPDDGKVIVVEAVLPKTPETNDAYKAVSQMDVLMMTQNPGGKERCEQEFMDLATAAGFSGIRYECHVNLFWVMEFFK
>rna-XM_014644264.2
MAEEATDSRKQARLAIMELANMISVPMALNAVVRLNVADAIWNSGANIPISAAQILPRILPAGDAENLQRLLRILTSYGVFKEHVDAGERKYSLTDVGKTLVTDEQGLSYGAYVLQHHQDALMRAWTLVHEAVVDPTKEPFERANGEGAYGYYLKQEEMNELMVKAMSGVSVPFMRAMLEGYDGFQGVERLVDVGGSGGDCLRMILQKHPSIKEGINFDLPEVVAKAPPTPYVTHVGGDMFKSIPQGDAIFMKWVLTTWTDEEIKQIMRNCHKALPEGGKVIACEPVLPEHSDESHRTRALLEGDIFVMTIYRAKGKHRTEEQFRQLAIDAGFPRFRAIHVDHFYTVLEFQK
>rna-XM_014643624.2
MAEMLESSRKVVNGREEYLKREEEEEEEDELAFCMEKTVSFVVPMALKTLSELRVFDILAKGGKLCAKEIAVEIGSKNPEAPAMLDRLLSLLVSHSLLSCSISQQEPHPQKFYTLSPASRYFVTDPQAVSLGSSVKLLLDDIFLKSWSELKGAILEGGVAFDRAHGMHAFEYPRVDPRFNEVFNNGMIGLTTVFMKRILELYNGFEHVTRLVDVGGGYGVNLKLIKSKHPHIQAINFDLPHVVENAPLHSGVEHVGGDMFESVPSGDAIFMKWVLHDWSDEHCVKLLKNCYKGIPDDGKVIVVDSIVSTVPERSVTAKSALGSDVIMMTENPGGKERTRQQIIELAEASGFSGIRFICSICGNWVMEFYK
>rna-XM_014648712.2
MAEQSMKEESAEEVVSDEEAFLFAMELAGGSALPMVLKSAIELGILETIAKAGPGAHLSPSEIAAQIPNIKNPNAPAMLDRMFRLLASYNILKLRFPDGNMSERHYGLHPKAKYLVNNQDAVSVAAYFLMEHDKALKEMWYKLTESVEEGGFPFNKAYGMNVFEFHDANPRFNRLFNKGLSDCSSITMKKILEIYKGFEGVGSLVDVGGGTGAVISMIASKYSSMKCLNFDLPHVIKEAPPYAGVEHVGGDMFVSVPKADAIFMKWVCHDWNDEQCLKLLKNCYDSLPDTGKVILVEGLIPETPNSKLASKCEFQMDIVMLCHSPNGKERTKKEYEALAKGTGFHGFRIACCVFNTYVIEFLKKA
>rna-XM_014647574.1
MVDSFIDVERVTEPTFKVPLDVVYAGCNRKVNHLFNDAMENDTRLISSLMIEKCKGTFTRLKSLVDVGGGTGTMAKAIAKSFPKMQCIVLDLPHVVAGLQGAENLKYVGGDMFEAIPPADSILLKWIMHDWSDEECMKILKKCKEAIRKEGKKGKVIIIETVMDDEKRDDDDEFVETQLLFDILMMGFFVESSHQTSKSLECSGMKMMSDSIVISENLIQELIKKTVVICLLGVSLKETCIELTI
>rna-XM_014658510.2
MGESTVVSTNNLFTTCPKKCDEGARLSAMLLSTTVVYPAVLNAAIELNLFEIIAKGTPHGSFMSSHEIASKLPNQHPDLPNRLDRMLRLLASYSVLTSSTRTTQHGATETVXXLSQIGQYYAPDATRGYFASFASFLSCPALSPLWLNFKEXVVDADVDLFKKLHXVTTYQYMEKNPKMXEIFNKSMAXXCVTDMNRILDIYXGFEGISTLVDXGGGNGQNLKMIVSKYPSIKGINFDLPQVIENAPLLSGVEHVGGDMFARVPEGDAMTLKAVLHNWSDEKCVEILSNCRKALSRDGKVVVLEFIMPEKPEATEQSQLVSSLDNLMFITAGGKERTEKEYENLCKLAGFSKFNVACHASSGPGVMEFYK
>rna-XM_022785244.1
MLTWECYSFNRGDAGFSSQICISISIRNNHFIHTSQPYNTNQKQSSTRPRLDGKAKTAKLVRKTEHKLFLRQHSASINEFNTILQKVQKCPFLCQHISLVDVGGGTGAIINMIVSKVSQYQGFLTSNFTLTFLLVFQKPTLFL
>rna-XM_014658511.2
MEESKVVSKNSLFTICPQKCDEDARVSAMLLSATMVYPAVLNAAIELNLFEIIAKATPHGSLMSSHEIASKLPNQHPDLPNRLDRMLRLLASYSVLTSSTRTTQHGATETVYGLSQLGQYYAPDATRGYFASFASFLSCPALSPLWLNFKEAVVDADVDLFKKLHGVTTYQYMEKNPKMNEIFNXXMADLXXXDMNRILDIYXGFEGISTLVDXGGGNGQNXKMIVSKYPSIKGINFDLPQVIENAPLLSGVEHVGGDMFARVPEGDAMTLKAVLHNWSDEKCVEILSNCRKALSGDGKVVVLEFIMPEKPEATEQSQLVSSLDNLMFITAGGKERTEKEYENLCKLAGFSKFNVSCHASSGPGVMEFYK
>rna-XM_022776075.1
MAPSEETNNGDAIQLKHVEEEQDGLLFALNMVSSMAFPLSVKTANELGIFDIIAKAGEGAKLSAEEITEKVGIKNPQAPTMVDRILRLLASHSMLSSCLGEEGHNSGKRLYSLTYASKYFVSDSDGVSFGPSLDLILGKVFLDSWTELKGAIAEGGIAFNRVYGMNPFEYQAVDPTYNDVFNKAMFNITTIITNRILELYDGFKNINRLVDVGGSLGINLKLITSKYPNVQGVNFDLPHVIQHAPTYPGVEHVAGDMFESVPNGDAIFMKWILHDWGDEECVKLLKNCYKAIPSDGKVIVVDTIVPALPDSTVTARNGFQADLLMMAQNPGGKERTQNEFMELALSSGFTGIRFVCFVSGFWIMEFFK
>rna-XM_014635401.2
MGSNSKEVEKVDDAYRSAVLLCFSRVLPAILNAAIDINLFDVIAKAKGSSDDSSFSASEIASLLPNQHPQLANRLERMLPLLVSYSLLRCSIRTNQDGKRERVYSLTPVGQYFAYDHQGISLAPLSTLLHRGFHDLWKDAKGAFLDPNCSNHFESVFGMLSYQYMEKDAELNQMFYKAMAHAGPIEVKRVLKVYKGFEGLSTLVDVGGGVGETLKLILSAYPSIKGINFDLPQMIQDAPPHPGVEHVGGDMFESVPSGDAILVKSICHNWADEDCIKFLRNCHKALPAHGKVIVLDYIIQEIPDSSDASKHSTIVDNHMLLAHGGRERTESEFENLCKSSGFFKFRVACNDISATVGVMEFYK
MELCFSEKDTETTLRAMVLGSNVVFPAALNAAIELNVFDIIAKEGSAESGGFMSPPEIASKLLIPRQQQHHRDLANRLERLLRLLASYSLLTVSSRSDGDGGSVRVYGVSESGKYFVRDENGDGYLASFTSFLCHPALSGVWLNFKEVVIDPEIDLFKKVHGMSKFEYFGKYPEINHVFNTAMHDICTTHMKKILEVYTGYEGISTLVDVGGGIGQCLKIIISKYPSIKGINFDLPHVIENSSPIPGVEHVGGNMFEGVPQGDAIMLKAITHNWSDEKVIELLSNCHKALPPKGKVIVGDFILPEDPEPTNEHKMISILDNIMFITPGGRERTEKEFDSLGKSSGFSRFEVVCRAFSTMAVMEFYK
>rna-XM_014643619.2
MTSLPNSRLNGEEKKKEAEEREDEESFSRAMQLVSSXVLPMAVQSATELGVFEVLKEAGEGAKLSAKDIXSKISCTNPEAASMLDRLLXLLSSHSILHSXLXSDNLVPPTFHRLYSITPLATFFARNSDGVSLGPLMAVTLDKIFLHSWSELKNAIREGGIPFNRVYGTHAFEYPRLDSRFNKVFNTGMINHTTLVMKRVLESYKGFDGIKSLVDVGGGLGINIKMITSKYPHIHGINFDLPHVIQDAPSYPGVDHVCGDMFENVPKGDAIFLKWILHDWSDEQCVKLLKNCYDAIPDDGKVIVMEAVLPTTPETNSAVYKAILELDVSMMTQNPGGKERCEQEFMDLATAAGFSGIRYECRANIFSVMEFFK
>rna-XM_014643970.1
MGSNCEEIDGEENDPCLSALLLSFSPMVYTAVLNASIELNLFEIIAKATKTTTPLGVSASEIASQLPIQHKKLPQRLDRMLSVLASHSLLTCSTLTNQDGKVQRLFQLSPSGKYFTNAEATASLALFTTFMNHPKLVQAFLNFKEIVLDCDKGLYMKVHGMPIFEGIQSDPTWNHIFNEAMANICRIEMTKILEIYSGFEGISLLIDVGGGVGQSLNIIISKYPSIKGVNFDLPQVIKQAPPYPGIEHVEGDMFESVPKGDAILLKGILHNWSDENCLKVLNNCYKALPENGKVVVVDFIMPEAIGSSEADKMVASFDNLMFLDGGSERTEKEFMNLCQISAFSSFRVVSRAFTALGVMEFYKN
>rna-XM_014643622.2
MENLPNSKLNGEEKKKEAEEREDEESFSRAMQLVSSXVLPMAVQSATELGVFEVLKEAGEGAKLSAKDIXSKISCTNPEAASMLDRLLXLLSSHSILHSSLVSDNLVPPTFHRLYSITPLATFFARNSDGVSLGPLMALLQDKIFLHSWTELKDAIREGGIPFNRAYGTHAFEYPRLDSRFNNVFNTAMINHTTLVMKRVLESYKGFEGIKRLVDVGGGLGINISLITSKYPHIHGINFDLPHVIQDAPSYPGVEHVGGDMFENVPKGDATFMKWILHDWSDEQCVKLLKNCYDAIPDDGKVIVVEAVLPKTPETNDAYKAVSQMDVLMMTQNPGGKERCEQEFMDLATAAGFSGIRYECHVNLFWVMEFFK
>rna-XM_014644264.2
MAEEATDSRKQARLAIMELANMISVPMALNAVVRLNVADAIWNSGANIPISAAQILPRILPAGDAENLQRLLRILTSYGVFKEHVDAGERKYSLTDVGKTLVTDEQGLSYGAYVLQHHQDALMRAWTLVHEAVVDPTKEPFERANGEGAYGYYLKQEEMNELMVKAMSGVSVPFMRAMLEGYDGFQGVERLVDVGGSGGDCLRMILQKHPSIKEGINFDLPEVVAKAPPTPYVTHVGGDMFKSIPQGDAIFMKWVLTTWTDEEIKQIMRNCHKALPEGGKVIACEPVLPEHSDESHRTRALLEGDIFVMTIYRAKGKHRTEEQFRQLAIDAGFPRFRAIHVDHFYTVLEFQK
>rna-XM_014643624.2
MAEMLESSRKVVNGREEYLKREEEEEEEDELAFCMEKTVSFVVPMALKTLSELRVFDILAKGGKLCAKEIAVEIGSKNPEAPAMLDRLLSLLVSHSLLSCSISQQEPHPQKFYTLSPASRYFVTDPQAVSLGSSVKLLLDDIFLKSWSELKGAILEGGVAFDRAHGMHAFEYPRVDPRFNEVFNNGMIGLTTVFMKRILELYNGFEHVTRLVDVGGGYGVNLKLIKSKHPHIQAINFDLPHVVENAPLHSGVEHVGGDMFESVPSGDAIFMKWVLHDWSDEHCVKLLKNCYKGIPDDGKVIVVDSIVSTVPERSVTAKSALGSDVIMMTENPGGKERTRQQIIELAEASGFSGIRFICSICGNWVMEFYK
>rna-XM_014648712.2
MAEQSMKEESAEEVVSDEEAFLFAMELAGGSALPMVLKSAIELGILETIAKAGPGAHLSPSEIAAQIPNIKNPNAPAMLDRMFRLLASYNILKLRFPDGNMSERHYGLHPKAKYLVNNQDAVSVAAYFLMEHDKALKEMWYKLTESVEEGGFPFNKAYGMNVFEFHDANPRFNRLFNKGLSDCSSITMKKILEIYKGFEGVGSLVDVGGGTGAVISMIASKYSSMKCLNFDLPHVIKEAPPYAGVEHVGGDMFVSVPKADAIFMKWVCHDWNDEQCLKLLKNCYDSLPDTGKVILVEGLIPETPNSKLASKCEFQMDIVMLCHSPNGKERTKKEYEALAKGTGFHGFRIACCVFNTYVIEFLKKA
>rna-XM_014647574.1
MVDSFIDVERVTEPTFKVPLDVVYAGCNRKVNHLFNDAMENDTRLISSLMIEKCKGTFTRLKSLVDVGGGTGTMAKAIAKSFPKMQCIVLDLPHVVAGLQGAENLKYVGGDMFEAIPPADSILLKWIMHDWSDEECMKILKKCKEAIRKEGKKGKVIIIETVMDDEKRDDDDEFVETQLLFDILMMGFFVESSHQTSKSLECSGMKMMSDSIVISENLIQELIKKTVVICLLGVSLKETCIELTI
>rna-XM_014658510.2
MGESTVVSTNNLFTTCPKKCDEGARLSAMLLSTTVVYPAVLNAAIELNLFEIIAKGTPHGSFMSSHEIASKLPNQHPDLPNRLDRMLRLLASYSVLTSSTRTTQHGATETVXXLSQIGQYYAPDATRGYFASFASFLSCPALSPLWLNFKEXVVDADVDLFKKLHXVTTYQYMEKNPKMXEIFNKSMAXXCVTDMNRILDIYXGFEGISTLVDXGGGNGQNLKMIVSKYPSIKGINFDLPQVIENAPLLSGVEHVGGDMFARVPEGDAMTLKAVLHNWSDEKCVEILSNCRKALSRDGKVVVLEFIMPEKPEATEQSQLVSSLDNLMFITAGGKERTEKEYENLCKLAGFSKFNVACHASSGPGVMEFYK
>rna-XM_022785244.1
MLTWECYSFNRGDAGFSSQICISISIRNNHFIHTSQPYNTNQKQSSTRPRLDGKAKTAKLVRKTEHKLFLRQHSASINEFNTILQKVQKCPFLCQHISLVDVGGGTGAIINMIVSKVSQYQGFLTSNFTLTFLLVFQKPTLFL
>rna-XM_014658511.2
MEESKVVSKNSLFTICPQKCDEDARVSAMLLSATMVYPAVLNAAIELNLFEIIAKATPHGSLMSSHEIASKLPNQHPDLPNRLDRMLRLLASYSVLTSSTRTTQHGATETVYGLSQLGQYYAPDATRGYFASFASFLSCPALSPLWLNFKEAVVDADVDLFKKLHGVTTYQYMEKNPKMNEIFNXXMADLXXXDMNRILDIYXGFEGISTLVDXGGGNGQNXKMIVSKYPSIKGINFDLPQVIENAPLLSGVEHVGGDMFARVPEGDAMTLKAVLHNWSDEKCVEILSNCRKALSGDGKVVVLEFIMPEKPEATEQSQLVSSLDNLMFITAGGKERTEKEYENLCKLAGFSKFNVSCHASSGPGVMEFYK
>rna-XM_022776075.1
MAPSEETNNGDAIQLKHVEEEQDGLLFALNMVSSMAFPLSVKTANELGIFDIIAKAGEGAKLSAEEITEKVGIKNPQAPTMVDRILRLLASHSMLSSCLGEEGHNSGKRLYSLTYASKYFVSDSDGVSFGPSLDLILGKVFLDSWTELKGAIAEGGIAFNRVYGMNPFEYQAVDPTYNDVFNKAMFNITTIITNRILELYDGFKNINRLVDVGGSLGINLKLITSKYPNVQGVNFDLPHVIQHAPTYPGVEHVAGDMFESVPNGDAIFMKWILHDWGDEECVKLLKNCYKAIPSDGKVIVVDTIVPALPDSTVTARNGFQADLLMMAQNPGGKERTQNEFMELALSSGFTGIRFVCFVSGFWIMEFFK
>rna-XM_014635401.2
MGSNSKEVEKVDDAYRSAVLLCFSRVLPAILNAAIDINLFDVIAKAKGSSDDSSFSASEIASLLPNQHPQLANRLERMLPLLVSYSLLRCSIRTNQDGKRERVYSLTPVGQYFAYDHQGISLAPLSTLLHRGFHDLWKDAKGAFLDPNCSNHFESVFGMLSYQYMEKDAELNQMFYKAMAHAGPIEVKRVLKVYKGFEGLSTLVDVGGGVGETLKLILSAYPSIKGINFDLPQMIQDAPPHPGVEHVGGDMFESVPSGDAILVKSICHNWADEDCIKFLRNCHKALPAHGKVIVLDYIIQEIPDSSDASKHSTIVDNHMLLAHGGRERTESEFENLCKSSGFFKFRVACNDISATVGVMEFYK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University