Enzyme
A cytochrome P-450 (heme-thiolate) protein found in plants. Acts on a number of flavonoids, including the flavanone naringenin and the flavone apigenin. Does not act on 4-coumarate or 4-coumaroyl-CoA.
F3'H
Enzyme
Flavonoid 3'-hydroxylase
Enzyme name
EC:1.14.14.82
Entry
Oxidoreductases;Acting on paired donors, with incorporation or reduction of molecular oxygen;With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
Class
flavonoid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (3'-hydroxylating)
Sysname
a flavonoid + [reduced NADPH---hemoprotein reductase] + O2 = a 3'-hydroxyflavonoid + [oxidized NADPH---hemoprotein reductase] + H2O [RN:R03615]
Reaction
3'-hydroxyflavonoid [CPD:C02790];[oxidized NADPH---hemoprotein reductase] [CPD:C03161];H2O [CPD:C00001]
Product
Species information
Vanilla planifolia
Species name
Cultivated vanilla (Vanilla planifolia) is a species of monocot in the family Orchidaceae (orchid family).
Species info
Gene sequence info
Vanilla_planifolia.F3_H.fa
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>rna-gnl|WGS:JADCNL|Vpl01Ag02594.1
MLPLLFKVLIINLLFYVLISSLGALRAVYYGERRAFPTLRHPLGCLSVQAQSPEVSPLPPGPRGLPLLGYLTKVGPNPHQTFYNLSKIYGPLLHLRFGIVDVVVPSSAEVAAKLFRNDLKVVNRPKNSGAEHILYNYQDIGFVPYGPRWRMLRKLCALHLFSPKALDDLQDTRREEMDLFVGELAGKGGAVEVDVSREVAKCVANSLSRLLIGRRVFDAGQEKEAGEFKWMVMELMHLSGSFCVADFLPGLGWLDPQGLISRMKKLNRRFDAFLNRFMAEHREPNAAGDNNNSGKRDLLSVMLEQQENADGEGGKLTDVDIKALLVAMFAAGSDSTSITSEWALAELIRKPEILARAQAELDSAVGRNRLVMESDLSNLPMLQDIVKETLRLHPPAPISVPRVAVEDCEVDGYLIPKGSTILLNIWAIGRDPVAWPDEPNEFRPDRFLPGGKHEGEDLKGSHFGLIPFGAGRRICVGMNLGLRMVTFMTATMIHSFDWFLPEGQTGEDLDMVERANGLTLIKAVPLVARPVPRLKPEVYANL
>rna-gnl|WGS:JADCNL|Vpl04Ag08965.1
MDPALLFVILTVFCSTLFLTAIKRWNSHRLPLPPGPKGLPLLGYLTQLGPLPHQTFHRLSEKYGPLLHVRLGVVPVVVPCTATVAEKLLRNDIKFVNRPKNSSAEHVAYNYQDIGFLPYGPKWRMQRRLCSLHLFSSKALDDFQHSRQSELARLVYSMAEQSGRALRRRWTSARSWRNVSATRCLCFWLAAECSRRVRRWKSSGTW
>rna-gnl|WGS:JADCNL|Vpl04Ag08964.1
MKKLNQKFDKFLGMFIAEHRAELTSERHKGAVEDGKPCNRDLLSVMLELQENADGEDDKLTDIDIKALLLSMFSAGSDSNSILAEWALAELIRVPDVLSRAQTELDSVVGRDRLVSESDLPNLPLLQAIIKETLRLHPPAPISIPRMAVEDCEVDGYLIPKGATLLLNIWAIGRDPVAWPDTPLAFRPDRFLPGGRHEGWTSREPLRVAAFRHGKKDVRWDESRPALAWDVNGYFGALVRLVLTGG
>rna-gnl|WGS:JADCNL|Vpl07Ag15058.1
MGGRMFRRTIEKILNHFIMPNVADFYPVVAPLDPQRYGRKVKRFQVWMDEYLNRIVQSRETSLSEREVEEKKMPKDLLEKLLELMHEGDPLVSSFSVADLRHLFASIIGASTDNNTTTIEWAMAELLYEPDRMRKAQHELDTVVGRDRPVEESDIPQLRYLGAVVKETLRLHPPVPLLVPHRPSSDCVAGGFAIPAGTAVIINAWAIHRDPSRWEDPDEFRPERFLQEGREQCESLGGNEFGYLPFGAGRRACAAMVLAERMTLFALASLLHSFEWGLPEGAHLELADTFGIVLRKAEPLVVVPKARLSKPELYV
>rna-gnl|WGS:JADCNL|Vpl09Ag18227.1
MAPILVLVSFFTLIFLLSNFQKLKKSKSRRRPLPPGPKGWPILGYLPFLGPKPHQTFHALSNTYGPLLHLRLGTVDVIVPCSADMASKLLRNDMNFIQRPPNSAAKHIAYNYMGLGFSPYGPRWRMLRKLCTLQLFSTKALDGLQHARRGEVSRFVRRLAEANDRKNGSAATVDVSSEIAACVVNSLSQLLVGRRVFDDGEEVKEFKEMIMDLMYLTGAFHVGDFVPGIGWLDPQGLVKRMKRLHRNFDDFLNKVIEDYRGTTRSDNEKKASVDDGKGNEEGTNRRRNLLSVLLDLKENADGKDGSLKDIDIKTLFQDVFAAGSDTTTITAEWTLAELIRHPDMLARAQAELDDVVGRNRLVEESDLPNLPYLQAVLKETFRLHPPGPLSVPRMAVADCEVGGYLIPKGSNLLLNVWAIGRDPEVWPDEPLEFRPDRFLPGGRHEGVEVRGNHFGLVPFGAGRRMCAGINLGLRMVHLVTATMMHSFDWSLPNGLQPCDLDMEEKFNGLTLHRIEPLLACPLPRLAPHVYQNL
>rna-gnl|WGS:JADCNL|Vpl09Ag18232.1
MFSNKVIDDYRATTTSEKEKKALVDGRKNDDEGKNRTRNLLSVLLDLKENADGNGGSLNGIDIKALVQNVCDAGRESTTITKEWALAGLLRHPDVMARAQAELDDVVGRNRPVEESDMLNLPYLQTVTKEAFRLHPLGLLSVPQMAVVDCEVGLYLVLKGSTLLLNIWAVGRHPEAWSDEPLEFRPDRFLPEGGYTWG
>rna-gnl|WGS:JADCNL|Vpl09Ag18229.1
MTWSAETDSWKNRTYPIWPYLQAVLKETFRLHPPGPLSVPRMAVADCEVGGYLIPKGSNLLLNIWAIGRDPEAWPDKPLEFRPDRFLPGGRHEGVEVRGNHFGLVPFGAGRRMCVGMNLGLRMVHLVTATILHSFDWGLPNGLQPCDLDMEENSNGLTLHRVEPILACPLPRLAPHVYQNL
>rna-gnl|WGS:JADCNL|Vpl09Ag18230.1
MASKLLRNDMNFIERPPNSAAEHIAYNYMDLGFSPYGPRWRMLRKLCSLQLFSTKALDDFQHARRGEVSRFVRRLAEANDRKNGSAATVDVSREIAACVVNSLSQLLVGRRVFDDGEEVKEFKEMVMDLMYLTGAFHVGDFVPGIGWLDPQGLVKRMKRLHRNFDDFLNKVIEDYRETTRSDNEKKASVDDGKGNEEGTNRTRNLLNVLLDLKENADGNDGSLNDIDIKALLQVPPIP
>rna-gnl|WGS:JADCNL|Vpl12Ag23632.1
MALIGAVILLSFLVSVLLLRGSVQRSRRGHLPLPPGPKGWPVLGNLLQVGPNFHQTLYNLSKIHGPILHLRLGSVDFIIVNSKAAAETMLRIDLKFSSRPRTSATYHVSYKQQDMVFTPYGPRWRMLRKLCAVHLFSNKAMEHLRPIREDEVTRLVQKLSRNSSSLVDLSKEIHACATNAISRVLVGRRVFEAGDKAQEFKGMIEELMILASSINIGDFIDVLRWFDLHGLVAKMKKFHQRFDNFLERLIEEHRAGLTETGSANGDMLSILIDLANSQGNGDVVALTDADIKPLLQNMFIAGTETSSNTVEFAIVELIRQPELLARAQQEMDAVVGRGRLVTEGDLHNLPFLQAVVKETFRCHPVAPLSLPAWSPRTSRSMAI
>rna-gnl|WGS:JADCNL|Vpl13Ag24919.1
MTSFLILFFFALLLASLLLARDRRSHRHCRLPPGPTGWPLLGNILQLGSKPHQTLHALSKTYGPLLHLRFGSVHVIVASNATTAAHFLRTHDANFSSRPPNSGAEHIAYNYRDLVFAPYGPRWRMLRRLCALQLFSAKALENLRHVREEEVVCLVQGLARAGKPVDVGAAVNTCATNALSRALVGRRVFSVDGSGEGPEEFKEMVVELMRLAGVFNVGDFVPAIAWLDPQGLVRKMKKLHKRFDEFLNKLITEHQEMADKSNNDMLSLLVKLKDETDGEDVKLTDTEIKALLLNLFTAGTDTTSSTVEWALVELIRAPGLLGRLQDELDSVVGRDRLVSESDLSELPLLQAVVKETFRLHPSTPLSLPRVATEDCKVDGFFIPSGTTLLVNVWAIGRDPESWPDEPLAFRPDRFLPNGRHHGVDVKGGDFELIPFGAGRRVCAGLSLGLRMVQFMVATLVHAYNWVLMEGDQADGLDMEEAFGLTLRRAMPFVAHPVPRLSRKAYD
>rna-gnl|WGS:JADCNL|Vpl13Ag24920.1
MTSLLILFFLALLASLFFAGCRRSHSHRRLPPGPKGWPVLGSIPHLGSKPHQTLYALSKNHGPLLHLRLGSVHVIVVSTATTAAHFLRTHDANFSNRPSNSGAEHIAYNYRDLVFAPYGPRWRMLRRLCALQLFSAKALEDLRHVRGEEIARLVRLFSRAGKPMDVGANVNTCVTNALSLAVVGRRVFGSDDGAAEFKEMVVELMRLAGVFNVGDFVPALAWLDPQGIVKKMKKLHKRFDGFLNKLIIEHQKMADKSNDLLSVLLKLKEETDEERTKLTDIEIKALLLNLFVAGTETTSIAIEWALVELIRSPGLLGRVQEELDSVVGRDRLVSESDLSGLPLLQAVVKETFRLHPSTPLSLPREAAEDCEVDGFFIPRGATLLVNVWAIGRDPVAWPDEPLAFQPDRFLPGGLHHGVDVKGGDFELIPFGAGRRICAGLSLGLRMVQFMVATLVHAFDWASDDQFDMEEASGLSLRRAVPLVVRPVPRLSREAYDKEFYT
>rna-gnl|WGS:JADCNL|Vpl_s027Ag26252.1
MDPALLFVILTVFCSTLFLTAIKRWSSHRLPLPPGPKGLPLLGYLTQLGPLPHQTFHRLSEKYGPLLHVRLGVVPVVVPCTATVAEKLLRNDIKFINRPKNSSAEHVAYNYQDIGFLPYGPKWRMQRRLCSLHLFSSKALDDFQHSRQSELARLVYSMAEQSGKGSKATVDVGKELAECVGNALSLLLVGRRVFEEGPEVEEFRNMVMELMTLTGSFCIADFLPGIGWLDPQGLISRMKKLNQKFDKFLGMFIAEHRAELTSERPKGAVEDGKPCNRDLLSVMLELQENADGEGDKLTDIDIKALLLSMFSAGSDSNSILAEWALAELIRVPDVLSRAQAELDSVVGRDRLVSESDLPNLPLLQAIIKETLRLHPPAPISIPRMAVEDCEVDGYLIPKGATLLLNIWAIGRDPVAWPDTPLAFRPDRFLPGGRHEGVDLKGSHFGLLPFGTGRRMCVGMNLGLRLLGMLTATLVHSFDWYLPEGERIEDLDMEEKANGLSVIRATPLVARPVPRLAPQAYLKT
MLPLLFKVLIINLLFYVLISSLGALRAVYYGERRAFPTLRHPLGCLSVQAQSPEVSPLPPGPRGLPLLGYLTKVGPNPHQTFYNLSKIYGPLLHLRFGIVDVVVPSSAEVAAKLFRNDLKVVNRPKNSGAEHILYNYQDIGFVPYGPRWRMLRKLCALHLFSPKALDDLQDTRREEMDLFVGELAGKGGAVEVDVSREVAKCVANSLSRLLIGRRVFDAGQEKEAGEFKWMVMELMHLSGSFCVADFLPGLGWLDPQGLISRMKKLNRRFDAFLNRFMAEHREPNAAGDNNNSGKRDLLSVMLEQQENADGEGGKLTDVDIKALLVAMFAAGSDSTSITSEWALAELIRKPEILARAQAELDSAVGRNRLVMESDLSNLPMLQDIVKETLRLHPPAPISVPRVAVEDCEVDGYLIPKGSTILLNIWAIGRDPVAWPDEPNEFRPDRFLPGGKHEGEDLKGSHFGLIPFGAGRRICVGMNLGLRMVTFMTATMIHSFDWFLPEGQTGEDLDMVERANGLTLIKAVPLVARPVPRLKPEVYANL
>rna-gnl|WGS:JADCNL|Vpl04Ag08965.1
MDPALLFVILTVFCSTLFLTAIKRWNSHRLPLPPGPKGLPLLGYLTQLGPLPHQTFHRLSEKYGPLLHVRLGVVPVVVPCTATVAEKLLRNDIKFVNRPKNSSAEHVAYNYQDIGFLPYGPKWRMQRRLCSLHLFSSKALDDFQHSRQSELARLVYSMAEQSGRALRRRWTSARSWRNVSATRCLCFWLAAECSRRVRRWKSSGTW
>rna-gnl|WGS:JADCNL|Vpl04Ag08964.1
MKKLNQKFDKFLGMFIAEHRAELTSERHKGAVEDGKPCNRDLLSVMLELQENADGEDDKLTDIDIKALLLSMFSAGSDSNSILAEWALAELIRVPDVLSRAQTELDSVVGRDRLVSESDLPNLPLLQAIIKETLRLHPPAPISIPRMAVEDCEVDGYLIPKGATLLLNIWAIGRDPVAWPDTPLAFRPDRFLPGGRHEGWTSREPLRVAAFRHGKKDVRWDESRPALAWDVNGYFGALVRLVLTGG
>rna-gnl|WGS:JADCNL|Vpl07Ag15058.1
MGGRMFRRTIEKILNHFIMPNVADFYPVVAPLDPQRYGRKVKRFQVWMDEYLNRIVQSRETSLSEREVEEKKMPKDLLEKLLELMHEGDPLVSSFSVADLRHLFASIIGASTDNNTTTIEWAMAELLYEPDRMRKAQHELDTVVGRDRPVEESDIPQLRYLGAVVKETLRLHPPVPLLVPHRPSSDCVAGGFAIPAGTAVIINAWAIHRDPSRWEDPDEFRPERFLQEGREQCESLGGNEFGYLPFGAGRRACAAMVLAERMTLFALASLLHSFEWGLPEGAHLELADTFGIVLRKAEPLVVVPKARLSKPELYV
>rna-gnl|WGS:JADCNL|Vpl09Ag18227.1
MAPILVLVSFFTLIFLLSNFQKLKKSKSRRRPLPPGPKGWPILGYLPFLGPKPHQTFHALSNTYGPLLHLRLGTVDVIVPCSADMASKLLRNDMNFIQRPPNSAAKHIAYNYMGLGFSPYGPRWRMLRKLCTLQLFSTKALDGLQHARRGEVSRFVRRLAEANDRKNGSAATVDVSSEIAACVVNSLSQLLVGRRVFDDGEEVKEFKEMIMDLMYLTGAFHVGDFVPGIGWLDPQGLVKRMKRLHRNFDDFLNKVIEDYRGTTRSDNEKKASVDDGKGNEEGTNRRRNLLSVLLDLKENADGKDGSLKDIDIKTLFQDVFAAGSDTTTITAEWTLAELIRHPDMLARAQAELDDVVGRNRLVEESDLPNLPYLQAVLKETFRLHPPGPLSVPRMAVADCEVGGYLIPKGSNLLLNVWAIGRDPEVWPDEPLEFRPDRFLPGGRHEGVEVRGNHFGLVPFGAGRRMCAGINLGLRMVHLVTATMMHSFDWSLPNGLQPCDLDMEEKFNGLTLHRIEPLLACPLPRLAPHVYQNL
>rna-gnl|WGS:JADCNL|Vpl09Ag18232.1
MFSNKVIDDYRATTTSEKEKKALVDGRKNDDEGKNRTRNLLSVLLDLKENADGNGGSLNGIDIKALVQNVCDAGRESTTITKEWALAGLLRHPDVMARAQAELDDVVGRNRPVEESDMLNLPYLQTVTKEAFRLHPLGLLSVPQMAVVDCEVGLYLVLKGSTLLLNIWAVGRHPEAWSDEPLEFRPDRFLPEGGYTWG
>rna-gnl|WGS:JADCNL|Vpl09Ag18229.1
MTWSAETDSWKNRTYPIWPYLQAVLKETFRLHPPGPLSVPRMAVADCEVGGYLIPKGSNLLLNIWAIGRDPEAWPDKPLEFRPDRFLPGGRHEGVEVRGNHFGLVPFGAGRRMCVGMNLGLRMVHLVTATILHSFDWGLPNGLQPCDLDMEENSNGLTLHRVEPILACPLPRLAPHVYQNL
>rna-gnl|WGS:JADCNL|Vpl09Ag18230.1
MASKLLRNDMNFIERPPNSAAEHIAYNYMDLGFSPYGPRWRMLRKLCSLQLFSTKALDDFQHARRGEVSRFVRRLAEANDRKNGSAATVDVSREIAACVVNSLSQLLVGRRVFDDGEEVKEFKEMVMDLMYLTGAFHVGDFVPGIGWLDPQGLVKRMKRLHRNFDDFLNKVIEDYRETTRSDNEKKASVDDGKGNEEGTNRTRNLLNVLLDLKENADGNDGSLNDIDIKALLQVPPIP
>rna-gnl|WGS:JADCNL|Vpl12Ag23632.1
MALIGAVILLSFLVSVLLLRGSVQRSRRGHLPLPPGPKGWPVLGNLLQVGPNFHQTLYNLSKIHGPILHLRLGSVDFIIVNSKAAAETMLRIDLKFSSRPRTSATYHVSYKQQDMVFTPYGPRWRMLRKLCAVHLFSNKAMEHLRPIREDEVTRLVQKLSRNSSSLVDLSKEIHACATNAISRVLVGRRVFEAGDKAQEFKGMIEELMILASSINIGDFIDVLRWFDLHGLVAKMKKFHQRFDNFLERLIEEHRAGLTETGSANGDMLSILIDLANSQGNGDVVALTDADIKPLLQNMFIAGTETSSNTVEFAIVELIRQPELLARAQQEMDAVVGRGRLVTEGDLHNLPFLQAVVKETFRCHPVAPLSLPAWSPRTSRSMAI
>rna-gnl|WGS:JADCNL|Vpl13Ag24919.1
MTSFLILFFFALLLASLLLARDRRSHRHCRLPPGPTGWPLLGNILQLGSKPHQTLHALSKTYGPLLHLRFGSVHVIVASNATTAAHFLRTHDANFSSRPPNSGAEHIAYNYRDLVFAPYGPRWRMLRRLCALQLFSAKALENLRHVREEEVVCLVQGLARAGKPVDVGAAVNTCATNALSRALVGRRVFSVDGSGEGPEEFKEMVVELMRLAGVFNVGDFVPAIAWLDPQGLVRKMKKLHKRFDEFLNKLITEHQEMADKSNNDMLSLLVKLKDETDGEDVKLTDTEIKALLLNLFTAGTDTTSSTVEWALVELIRAPGLLGRLQDELDSVVGRDRLVSESDLSELPLLQAVVKETFRLHPSTPLSLPRVATEDCKVDGFFIPSGTTLLVNVWAIGRDPESWPDEPLAFRPDRFLPNGRHHGVDVKGGDFELIPFGAGRRVCAGLSLGLRMVQFMVATLVHAYNWVLMEGDQADGLDMEEAFGLTLRRAMPFVAHPVPRLSRKAYD
>rna-gnl|WGS:JADCNL|Vpl13Ag24920.1
MTSLLILFFLALLASLFFAGCRRSHSHRRLPPGPKGWPVLGSIPHLGSKPHQTLYALSKNHGPLLHLRLGSVHVIVVSTATTAAHFLRTHDANFSNRPSNSGAEHIAYNYRDLVFAPYGPRWRMLRRLCALQLFSAKALEDLRHVRGEEIARLVRLFSRAGKPMDVGANVNTCVTNALSLAVVGRRVFGSDDGAAEFKEMVVELMRLAGVFNVGDFVPALAWLDPQGIVKKMKKLHKRFDGFLNKLIIEHQKMADKSNDLLSVLLKLKEETDEERTKLTDIEIKALLLNLFVAGTETTSIAIEWALVELIRSPGLLGRVQEELDSVVGRDRLVSESDLSGLPLLQAVVKETFRLHPSTPLSLPREAAEDCEVDGFFIPRGATLLVNVWAIGRDPVAWPDEPLAFQPDRFLPGGLHHGVDVKGGDFELIPFGAGRRICAGLSLGLRMVQFMVATLVHAFDWASDDQFDMEEASGLSLRRAVPLVVRPVPRLSREAYDKEFYT
>rna-gnl|WGS:JADCNL|Vpl_s027Ag26252.1
MDPALLFVILTVFCSTLFLTAIKRWSSHRLPLPPGPKGLPLLGYLTQLGPLPHQTFHRLSEKYGPLLHVRLGVVPVVVPCTATVAEKLLRNDIKFINRPKNSSAEHVAYNYQDIGFLPYGPKWRMQRRLCSLHLFSSKALDDFQHSRQSELARLVYSMAEQSGKGSKATVDVGKELAECVGNALSLLLVGRRVFEEGPEVEEFRNMVMELMTLTGSFCIADFLPGIGWLDPQGLISRMKKLNQKFDKFLGMFIAEHRAELTSERPKGAVEDGKPCNRDLLSVMLELQENADGEGDKLTDIDIKALLLSMFSAGSDSNSILAEWALAELIRVPDVLSRAQAELDSVVGRDRLVSESDLPNLPLLQAIIKETLRLHPPAPISIPRMAVEDCEVDGYLIPKGATLLLNIWAIGRDPVAWPDTPLAFRPDRFLPGGRHEGVDLKGSHFGLLPFGTGRRMCVGMNLGLRLLGMLTATLVHSFDWYLPEGERIEDLDMEEKANGLSVIRATPLVARPVPRLAPQAYLKT
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University