Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Vaccinium macrocarpon
Species name
American cranberry (Vaccinium macrocarpon) is a species of eudicot in the family Ericaceae (heath family).
Species info
Gene sequence info
Vaccinium_macrocarpon.OMT.fa
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>vmacro17268-RA_Vaccinium_macrocarpon_Stevens_v1
MEGETSREEEEVQAQVDIWEYVFGFVDTAVVKCAIELGIPDALEARDIRHFSPHGEDIRRYAAENPGHSQLINDVMASDARVAVLAVIEGCPEVFDGVESVVDVGGGDGTTLRLLVKAFPRIRGINFDLPHVVSVAPDSVGFEHVGGDMFVSVPKADAAYLTVPYVSIRSLDDIGDLFLPLEFLNLYWVLHDWDDDECIKILRKCREAIPKDKGKVTIVEAVVEEDNNNNKLEFVRLMLDMVMMAHTNKGKDRTSKEWAYVLSESGFSRHTIKPTKAVQSVIEAYP
>vmacro17263-RA_Vaccinium_macrocarpon_Stevens_v1
MLSLMLVVRVQCQVDNHQIGHRLVLYPTLCCWFAIGRGAISRDGPTMLSDLSSALGCSPSILHSIMRFLVHSKIFKEGLTGYFQTPLSRLLMKNGEKSLPDFLLYANDPEMLAPWHSLSARVLAMRARHLPCLVGFLGTSLRILLENDFQNGTSVGPSQHLVSGGRRWRRWDHSPVVGQGGGDGTTLRLLAKAFPWIRGINFDLPHVVSIAPDCVGVVHVGGDMFVSVSKADVAYLKRGCSERQRKVIMIEAVVEEDKNDKLEYVRLTLDMVMMTHTNKGKERTAKEWA
>vmacro17267-RA_Vaccinium_macrocarpon_Stevens_v1
MEGEIRREEEEVAQAQVDIWKYVFGYVDMAVVKCAIELGIPDVLETRDGSMTLSELSFGLGCSSSAIHRIMRPAMLAPWHALSAHVLARESPAFELTHGEDMWRYAAENPADSKLINEAMACDARVGVPAIIEGCPEKVLHDWDDDKCIQILRNCREAVPKDKGKVIIVDTVVEEDKNNAGVCEADVRHGDDGSHNQWQRKDCKGMGLRFDPVWIQSTHYNPHQSCSVTYCGLPLICRIMNPCISIFRHKQLRPCLKIILNCYHV
>vmacro17265-RA_Vaccinium_macrocarpon_Stevens_v1
MLQSGKSGIPDWITDTAVVKCAIELGIPDALETRDGPTTLSDLSSALGCSPSALHRIMRFLVHRKIFKEGPTGYLQTPLSRLLMKKGEKSLANFLLCTNDPVMLAPWHSLSSRVLANESPAFESAHGEDVWRYAAKNPAKSKLINDAMASGSRVVVPAIIEECPDVFDGAASVVDVGGGDGTSLRLLAKAFPWIRGINFDLPHVVSVAPDCVGVEHVGGDMFVSVPKADVAYLKWVLHDWDDDECIQILRNCREAIPKDKGKVIIIEAVIEEDKNDKLEYVRLMFDMAMMAHTNKGKERTAKEWAYVLTKSGFSRHTIKPIKTGQSLIEAYP
>vmacro09239-RA_Vaccinium_macrocarpon_Stevens_v1
MRSQPLGVKALRLKSWFPGSEHIQSTEETPAEAKSDGTRHNPSERPDAKRFCIHSVKKTGGGSVYKGTVVFVSCTRNTKAYLKMDMRNAKESKELLHSQTHIWNHIFHFINSMSLKCAVQLDIPDIIKNHGGPMSLSELVSALSINPSKSRCVYRLMRILVHSGFFTKEKILGTTEEEEGYLLTPASSLLLKDEPLSVRPFLLGVLDPISIKPWHNVSEWFQNDHPTPFDTAHGKTFWDYMGHEPRISHAFNEGMASDAQLVTSVVVKDCKGVFEGLNSLVDVGGGNGTLAKAIADAFPKLECTVLDLPHVVAGLEGSGNLKFVGGDMFQAIPSTDAVLLKCVLHDWSDEESIKILKRCKEAIPSKGGKVIIIDMKVEINEKARDAESIETQLFFDMQMMILVTGRERTEKEWAKLFVDAGFSGYKITPILGLRSLIEVYP
>vmacro09240-RA_Vaccinium_macrocarpon_Stevens_v1
MMSMGSGDERSTELLHSQAHLWNQTLNFINLASLKCAVQLGIPDAIHRHGKPMTITQVCRATTTDPPLTPSLPMTLDQLVAALSIKQAKAQSVYRLMRVLVHSGFVIQEKVGDQDGYVLTPASRLLLKDEPLNARALLLHWLDPIITQPWKILSKCFHNDDPTAFDTTYGKSFWLVTEVLIKECKGVFEGLTSLVDVGGGTGTVSRTMHEDIKPHIINLNHGFSEAVATREGDERSGLEKEIESRGGGQRVNEDEDGDGDRDAVVEANAGGRLFRWLSPEEDFSWRRRRCIDQIALASQEDLQEVAIEMWDIILESIANLSLGPTNSIEVKEHQENLTKAIKEMLVMLRQELLDLYEVWVLLLSRLGSNRRRFRMHLDSRISLKTQQPKLQEFLLWNKLKKKISTHQPRSPTKDAKDNSPFVVEGGNTPPDDVIHLEDLEGPPAKLYDLTEDVQDPLEEVNLGSEDKLKPICESGKIPNSLFNYP
>vmacro03899-RA_Vaccinium_macrocarpon_Stevens_v1
MDHQNDQLGAKELCQAQSHICKHVFSFANSMCLKCAVQLGIPDAIHNHKQPITLPELVSSLHLPLEKTSSLHRLLRLLVHFGFFTTKNSNIDEGDQEGYVLTPSSRLLLKSEITNLSPFVRAMVDPVLVTPWHFLGDWFHGSDKTAFETAHGVGVWEFGDQNLKFNRTFNEAMASDSEMMNFVVGECKAVFEGLSSLADVGGGTGPIARIILDAFPHIKCTVFDLPHVVANLPESGNLKYVGGDMFDSIPSADAILLKHVLHNWSDEDCVKILKSCKDAIPSKDDGGKVIIIEMVIDGERDEHDVAETKLVFDVLMMVLLSGRERTEKEWEHIFLQAGFSHYKITPTFGSRSLIEVYP
MEGETSREEEEVQAQVDIWEYVFGFVDTAVVKCAIELGIPDALEARDIRHFSPHGEDIRRYAAENPGHSQLINDVMASDARVAVLAVIEGCPEVFDGVESVVDVGGGDGTTLRLLVKAFPRIRGINFDLPHVVSVAPDSVGFEHVGGDMFVSVPKADAAYLTVPYVSIRSLDDIGDLFLPLEFLNLYWVLHDWDDDECIKILRKCREAIPKDKGKVTIVEAVVEEDNNNNKLEFVRLMLDMVMMAHTNKGKDRTSKEWAYVLSESGFSRHTIKPTKAVQSVIEAYP
>vmacro17263-RA_Vaccinium_macrocarpon_Stevens_v1
MLSLMLVVRVQCQVDNHQIGHRLVLYPTLCCWFAIGRGAISRDGPTMLSDLSSALGCSPSILHSIMRFLVHSKIFKEGLTGYFQTPLSRLLMKNGEKSLPDFLLYANDPEMLAPWHSLSARVLAMRARHLPCLVGFLGTSLRILLENDFQNGTSVGPSQHLVSGGRRWRRWDHSPVVGQGGGDGTTLRLLAKAFPWIRGINFDLPHVVSIAPDCVGVVHVGGDMFVSVSKADVAYLKRGCSERQRKVIMIEAVVEEDKNDKLEYVRLTLDMVMMTHTNKGKERTAKEWA
>vmacro17267-RA_Vaccinium_macrocarpon_Stevens_v1
MEGEIRREEEEVAQAQVDIWKYVFGYVDMAVVKCAIELGIPDVLETRDGSMTLSELSFGLGCSSSAIHRIMRPAMLAPWHALSAHVLARESPAFELTHGEDMWRYAAENPADSKLINEAMACDARVGVPAIIEGCPEKVLHDWDDDKCIQILRNCREAVPKDKGKVIIVDTVVEEDKNNAGVCEADVRHGDDGSHNQWQRKDCKGMGLRFDPVWIQSTHYNPHQSCSVTYCGLPLICRIMNPCISIFRHKQLRPCLKIILNCYHV
>vmacro17265-RA_Vaccinium_macrocarpon_Stevens_v1
MLQSGKSGIPDWITDTAVVKCAIELGIPDALETRDGPTTLSDLSSALGCSPSALHRIMRFLVHRKIFKEGPTGYLQTPLSRLLMKKGEKSLANFLLCTNDPVMLAPWHSLSSRVLANESPAFESAHGEDVWRYAAKNPAKSKLINDAMASGSRVVVPAIIEECPDVFDGAASVVDVGGGDGTSLRLLAKAFPWIRGINFDLPHVVSVAPDCVGVEHVGGDMFVSVPKADVAYLKWVLHDWDDDECIQILRNCREAIPKDKGKVIIIEAVIEEDKNDKLEYVRLMFDMAMMAHTNKGKERTAKEWAYVLTKSGFSRHTIKPIKTGQSLIEAYP
>vmacro09239-RA_Vaccinium_macrocarpon_Stevens_v1
MRSQPLGVKALRLKSWFPGSEHIQSTEETPAEAKSDGTRHNPSERPDAKRFCIHSVKKTGGGSVYKGTVVFVSCTRNTKAYLKMDMRNAKESKELLHSQTHIWNHIFHFINSMSLKCAVQLDIPDIIKNHGGPMSLSELVSALSINPSKSRCVYRLMRILVHSGFFTKEKILGTTEEEEGYLLTPASSLLLKDEPLSVRPFLLGVLDPISIKPWHNVSEWFQNDHPTPFDTAHGKTFWDYMGHEPRISHAFNEGMASDAQLVTSVVVKDCKGVFEGLNSLVDVGGGNGTLAKAIADAFPKLECTVLDLPHVVAGLEGSGNLKFVGGDMFQAIPSTDAVLLKCVLHDWSDEESIKILKRCKEAIPSKGGKVIIIDMKVEINEKARDAESIETQLFFDMQMMILVTGRERTEKEWAKLFVDAGFSGYKITPILGLRSLIEVYP
>vmacro09240-RA_Vaccinium_macrocarpon_Stevens_v1
MMSMGSGDERSTELLHSQAHLWNQTLNFINLASLKCAVQLGIPDAIHRHGKPMTITQVCRATTTDPPLTPSLPMTLDQLVAALSIKQAKAQSVYRLMRVLVHSGFVIQEKVGDQDGYVLTPASRLLLKDEPLNARALLLHWLDPIITQPWKILSKCFHNDDPTAFDTTYGKSFWLVTEVLIKECKGVFEGLTSLVDVGGGTGTVSRTMHEDIKPHIINLNHGFSEAVATREGDERSGLEKEIESRGGGQRVNEDEDGDGDRDAVVEANAGGRLFRWLSPEEDFSWRRRRCIDQIALASQEDLQEVAIEMWDIILESIANLSLGPTNSIEVKEHQENLTKAIKEMLVMLRQELLDLYEVWVLLLSRLGSNRRRFRMHLDSRISLKTQQPKLQEFLLWNKLKKKISTHQPRSPTKDAKDNSPFVVEGGNTPPDDVIHLEDLEGPPAKLYDLTEDVQDPLEEVNLGSEDKLKPICESGKIPNSLFNYP
>vmacro03899-RA_Vaccinium_macrocarpon_Stevens_v1
MDHQNDQLGAKELCQAQSHICKHVFSFANSMCLKCAVQLGIPDAIHNHKQPITLPELVSSLHLPLEKTSSLHRLLRLLVHFGFFTTKNSNIDEGDQEGYVLTPSSRLLLKSEITNLSPFVRAMVDPVLVTPWHFLGDWFHGSDKTAFETAHGVGVWEFGDQNLKFNRTFNEAMASDSEMMNFVVGECKAVFEGLSSLADVGGGTGPIARIILDAFPHIKCTVFDLPHVVANLPESGNLKYVGGDMFDSIPSADAILLKHVLHNWSDEDCVKILKSCKDAIPSKDDGGKVIIIEMVIDGERDEHDVAETKLVFDVLMMVLLSGRERTEKEWEHIFLQAGFSHYKITPTFGSRSLIEVYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University