Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Urochloa fusca
Species name
Urochloa fusca is a species of monocot in the family Poaceae (grass family).
Species info
Gene sequence info
Urochloa_fusca.COMT.fa
Download
>Urofu.1G081900.1.v1.1
MAAHGEGFYGYLSRDLEFGELFGDAMGADSRFVAEIVVRECGEAFAGVTSLVDAGGGDGTTAKAIARSFPHVRCSVLELPQVVESVVVDGAVEFVAGDMMEFIPPVDVVLLKFVLHNWSDEDCVKILERSREAISTREPKGKVIIIDTVVGSASKQTLEAQLLMDLCMMVLTTGEE
>Urofu.1G304200.1.v1.1
MSPPPPPPAEARLAMMELANMISVPMALTAVIRLGVPSAVWAGGANAPLSAAELLPEGHPDPSVLERLLRLLAARGVFSEHGGSPRRFALTAVGRTLVPGPSGASYADYVLQHHQDALVAAWPRLHEAVLDPTGPEPFARANAGVPAYAYYGKDREANEVMLRAMTGVSEPFMEALLDGYAGGFDGVATLVDVGGSSGACLEMIMRRVGTITEGINFDLPDVVAAAPTIAGVSHVGGDMFKSIPSGDAIFMKWVLTTWTNDECTAILRNCHGALPDGGKVIACEPVVPEETDTSTRTRALLENDIFVMTTYRTQGRERSEDEFRQLGLAAGFTGFRAIYLDPFYAILEYKK
>Urofu.1G390000.1.v1.1
MAAARHLRSGLPLLRAHLAASESAAVAQGSRGFSSQVAKPTGKQVKVPEALYGGTGNYASALFLTAAKANTLDKVESEIKTVVEASKKSPLFSQFIKDLSVPKETRVKAITEIFAEAGFSDVTKNFLAVLADNGRLKYIERIAERFVDLTMAHKGEVKVVVRTVIPLPEKEEKELKETLQDILGKNKTILVEQKIDYSIMGGLVIEFGQKVFDMSIKTRAKQMEAFLRQPLEI
>Urofu.2G386300.1.v1.1
MGTATADDMAAVADEEACLYALHLSSSSILPMTLKSAIELGLLDVLETARKVEGGDAAAATTLLAPEQVVGRLPVAPNNPDAPGMVDRMLRLLASYDVVRCQVEEGEDGRLSRRYGAAPVCKWLTPNEDGVSMAALALMNQDKVLMESWYHLKDAVLEGGIPFNKAYGMTAFEYHGTDPRFNRVFNEGMRNNSVIITKKLLEFYTGFDGVGTLVDVGGGVGTTLHAITSRHPHIKGVNFDLPHVISEAPPLPGVEHVGGDMFESVPSGDAILMKWILHDWGDARCAALLRNCYNALPAHGKVIAVECILPTNPENTPKTQLVFHADMIMLAHNPGGKERYEREFEELVRGAGFIGIKATYIYANVWAIEFTK
>Urofu.2G127900.1.v1.1
MAEQEQSSSAAPASNDDDDHERMHALALLDGYVLPMTLKAAIELGLIDHLVAAEGRAVAVEELAAGMPRPAEAAARVDRMLRFLASHSVVRCAVEVAPDGEARRSYAAAPVCKWLAVNAGKKDSVAPAARMSLNKVFMDSWQYLKDAVLDGGSSFQRAHGVPMFEYLNSNDSSNKLFNEGIASRSTVINRKFVELLFSGFEGVGVLVDVGGGTGATLQMIKAQHKHLRGVNFDLPHVIAQSPPVEGVEHVGGNMFENVPCGDAILLKWILHNWGDEDCVKILKNCYTALPANGKVIVLEHILPGSPEHTLSAQFGFRLDVIMLNNFGSGKERTEREYTELIKKAGFSGEFKATYIFNNFWALEFMK
>Urofu.6G018900.1.v1.1
MGSTAADVAAVADEEACMYAMQLVSSSILPMTLKNAIELGLLEVLQKDPAAWLSPEEVVARLPVAPTNPDAAVMVDRMLRLLASYDVARCQMEDKDGKYSRRYAAAPVGKWLTPNEDGVSMAALALMNQDKVLMESWYYLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNRVFNEGMKNHSVIITKKLLEFYTGFQGVGTLVDVGGGIGATLHAITSHYPQIKGVNFDLPHVISEAPPFPGVTHVGGDMFKSVPAGDAILMKWILHDWSDAHCATILKNCYDALPTNGKVIIVECVLPVNTEATPKAQGVFHVDMIMLAHNPGGKERYEREFQELAKGAGFTGFKATYIYANAWAIEFTK
>Urofu.7G029900.1.v1.1
MSNPAAGAAGDGDEATCLHALELISASYISMTVKAAIELGLIDALSTAAGRSMTADELSAQLPAADKAEAAASVDRLLRFLASYNVVKCSTETGQNGEALRRYTAAPVCRWLTSNSTEGSLAPLAMFAVDEGYLPTWQHLGAAVAGGGPSAFERAHGMPMFPYMGTNARLNMVFNKAMAQQTVMVIRKLLERFKGFDSVGVLVDVGGGTGTALEMITFRYKHVRGINFDLPHALSKAPAIPGVQHVPGNMFEEVPHGDAIFLKSMLHLQNDDDCVKILKNCHRALPEHGKVIAMEIVLPAIPEATPVAQNPFRLDVIMLNNFRGGKERTEQEFLKLARDSDFGGEFRSTYIFANYWALEFSK
>Urofu.8G154300.1.v1.1
MATSSAEIMQAEAELCCHTIGYLKSTALHTAVKLGIPNIIHRHGGAASLSDLLAALPLLPPTRRPYLSRLMRVLAVAGIITAEDDVPAAAGETTAACVYRLNPVSHLLVDDDAGIHGGSGGCGGGGSSSLSPCVLVSTTPLYLLASLKFHQWLLCEGDDATPPAATPFAMAHGGDTFYGVAGRDAGVNKLFNEAMGASSQLLSGLVVRECGGVFAGVTSLVDVGGGDGTMARAIAEGFPHVRCSVLDLPQVVDASPPPRLVSAPRLSLLLVT
>Urofu.9G519100.1.v1.1
MAGYANATVAASHGHDTTSDDEACKHALELLSGFVVPMTLKAVIELGLIDELLAAGGRAVTPEHLVAARRWPRPAEAAAAVDRMLRFLASHSVVRCTTEAAAGPGGKPRRSDAAAPVCKWLATRDARQGSMAPLGLMNLDKAFMETWYYMKDAVSEGVTPTEKAYGTPLFEHLGSNEASNTLFNEAMAGHSEVITKKLLELYRGFDGLDVLVDVGGGTGATLRMITAQHEHLRGVNYDLPHVIAQAPPVQGVEHVGGSMFDYIPSGNAILLKWILHLWRDEECIKILKNCHRALPANGKVIVIEYVLPASPEPTLAAQGAFHLDVVMLNRLAGAKERTEQEFAELAAEAGFSGGCRATYIFAYAWALEFTK
MAAHGEGFYGYLSRDLEFGELFGDAMGADSRFVAEIVVRECGEAFAGVTSLVDAGGGDGTTAKAIARSFPHVRCSVLELPQVVESVVVDGAVEFVAGDMMEFIPPVDVVLLKFVLHNWSDEDCVKILERSREAISTREPKGKVIIIDTVVGSASKQTLEAQLLMDLCMMVLTTGEE
>Urofu.1G304200.1.v1.1
MSPPPPPPAEARLAMMELANMISVPMALTAVIRLGVPSAVWAGGANAPLSAAELLPEGHPDPSVLERLLRLLAARGVFSEHGGSPRRFALTAVGRTLVPGPSGASYADYVLQHHQDALVAAWPRLHEAVLDPTGPEPFARANAGVPAYAYYGKDREANEVMLRAMTGVSEPFMEALLDGYAGGFDGVATLVDVGGSSGACLEMIMRRVGTITEGINFDLPDVVAAAPTIAGVSHVGGDMFKSIPSGDAIFMKWVLTTWTNDECTAILRNCHGALPDGGKVIACEPVVPEETDTSTRTRALLENDIFVMTTYRTQGRERSEDEFRQLGLAAGFTGFRAIYLDPFYAILEYKK
>Urofu.1G390000.1.v1.1
MAAARHLRSGLPLLRAHLAASESAAVAQGSRGFSSQVAKPTGKQVKVPEALYGGTGNYASALFLTAAKANTLDKVESEIKTVVEASKKSPLFSQFIKDLSVPKETRVKAITEIFAEAGFSDVTKNFLAVLADNGRLKYIERIAERFVDLTMAHKGEVKVVVRTVIPLPEKEEKELKETLQDILGKNKTILVEQKIDYSIMGGLVIEFGQKVFDMSIKTRAKQMEAFLRQPLEI
>Urofu.2G386300.1.v1.1
MGTATADDMAAVADEEACLYALHLSSSSILPMTLKSAIELGLLDVLETARKVEGGDAAAATTLLAPEQVVGRLPVAPNNPDAPGMVDRMLRLLASYDVVRCQVEEGEDGRLSRRYGAAPVCKWLTPNEDGVSMAALALMNQDKVLMESWYHLKDAVLEGGIPFNKAYGMTAFEYHGTDPRFNRVFNEGMRNNSVIITKKLLEFYTGFDGVGTLVDVGGGVGTTLHAITSRHPHIKGVNFDLPHVISEAPPLPGVEHVGGDMFESVPSGDAILMKWILHDWGDARCAALLRNCYNALPAHGKVIAVECILPTNPENTPKTQLVFHADMIMLAHNPGGKERYEREFEELVRGAGFIGIKATYIYANVWAIEFTK
>Urofu.2G127900.1.v1.1
MAEQEQSSSAAPASNDDDDHERMHALALLDGYVLPMTLKAAIELGLIDHLVAAEGRAVAVEELAAGMPRPAEAAARVDRMLRFLASHSVVRCAVEVAPDGEARRSYAAAPVCKWLAVNAGKKDSVAPAARMSLNKVFMDSWQYLKDAVLDGGSSFQRAHGVPMFEYLNSNDSSNKLFNEGIASRSTVINRKFVELLFSGFEGVGVLVDVGGGTGATLQMIKAQHKHLRGVNFDLPHVIAQSPPVEGVEHVGGNMFENVPCGDAILLKWILHNWGDEDCVKILKNCYTALPANGKVIVLEHILPGSPEHTLSAQFGFRLDVIMLNNFGSGKERTEREYTELIKKAGFSGEFKATYIFNNFWALEFMK
>Urofu.6G018900.1.v1.1
MGSTAADVAAVADEEACMYAMQLVSSSILPMTLKNAIELGLLEVLQKDPAAWLSPEEVVARLPVAPTNPDAAVMVDRMLRLLASYDVARCQMEDKDGKYSRRYAAAPVGKWLTPNEDGVSMAALALMNQDKVLMESWYYLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNRVFNEGMKNHSVIITKKLLEFYTGFQGVGTLVDVGGGIGATLHAITSHYPQIKGVNFDLPHVISEAPPFPGVTHVGGDMFKSVPAGDAILMKWILHDWSDAHCATILKNCYDALPTNGKVIIVECVLPVNTEATPKAQGVFHVDMIMLAHNPGGKERYEREFQELAKGAGFTGFKATYIYANAWAIEFTK
>Urofu.7G029900.1.v1.1
MSNPAAGAAGDGDEATCLHALELISASYISMTVKAAIELGLIDALSTAAGRSMTADELSAQLPAADKAEAAASVDRLLRFLASYNVVKCSTETGQNGEALRRYTAAPVCRWLTSNSTEGSLAPLAMFAVDEGYLPTWQHLGAAVAGGGPSAFERAHGMPMFPYMGTNARLNMVFNKAMAQQTVMVIRKLLERFKGFDSVGVLVDVGGGTGTALEMITFRYKHVRGINFDLPHALSKAPAIPGVQHVPGNMFEEVPHGDAIFLKSMLHLQNDDDCVKILKNCHRALPEHGKVIAMEIVLPAIPEATPVAQNPFRLDVIMLNNFRGGKERTEQEFLKLARDSDFGGEFRSTYIFANYWALEFSK
>Urofu.8G154300.1.v1.1
MATSSAEIMQAEAELCCHTIGYLKSTALHTAVKLGIPNIIHRHGGAASLSDLLAALPLLPPTRRPYLSRLMRVLAVAGIITAEDDVPAAAGETTAACVYRLNPVSHLLVDDDAGIHGGSGGCGGGGSSSLSPCVLVSTTPLYLLASLKFHQWLLCEGDDATPPAATPFAMAHGGDTFYGVAGRDAGVNKLFNEAMGASSQLLSGLVVRECGGVFAGVTSLVDVGGGDGTMARAIAEGFPHVRCSVLDLPQVVDASPPPRLVSAPRLSLLLVT
>Urofu.9G519100.1.v1.1
MAGYANATVAASHGHDTTSDDEACKHALELLSGFVVPMTLKAVIELGLIDELLAAGGRAVTPEHLVAARRWPRPAEAAAAVDRMLRFLASHSVVRCTTEAAAGPGGKPRRSDAAAPVCKWLATRDARQGSMAPLGLMNLDKAFMETWYYMKDAVSEGVTPTEKAYGTPLFEHLGSNEASNTLFNEAMAGHSEVITKKLLELYRGFDGLDVLVDVGGGTGATLRMITAQHEHLRGVNYDLPHVIAQAPPVQGVEHVGGSMFDYIPSGNAILLKWILHLWRDEECIKILKNCHRALPANGKVIVIEYVLPASPEPTLAAQGAFHLDVVMLNRLAGAKERTEQEFAELAAEAGFSGGCRATYIFAYAWALEFTK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University