Enzyme
A cytochrome P-450 (heme-thiolate) protein found in plants. The enzyme is involved in flavonoid biosynthesis.
C4H
Enzyme
Cinnamate 4-hydroxylase
Enzyme name
EC:1.14.14.91
Entry
Oxidoreductases;Acting on paired donors, with incorporation or reduction of molecular oxygen;With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
Class
trans-cinnamate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating)
Sysname
trans-cinnamate + [reduced NADPH---hemoprotein reductase] + O2 = 4-hydroxycinnamate + [oxidized NADPH---hemoprotein reductase] + H2O[RN:R02253]
Reaction
4-hydroxycinnamate [CPD:C00811];[oxidized NADPH---hemoprotein reductase] [CPD:C03161];H2O [CPD:C00001]
Product
Species information
Areca catechu
Species name
Areca-nut (Areca catechu) is a species of monocot in the family Arecaceae (palm family).
Species info
Gene sequence info
Areca_catechu.C4H.fa
Download
>Acat_1g013550
MDLLLLEKALLGLFAAVTLAIAVSKLRGKRLKLPPGPLPVPIFGNWLQVGDDLNHRNLAALAKRFGDILLLRMGQRNLVVISSPDLAREVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNRHGWEEEARRVVENVKANPKAATEGIVLRRRLQLMMYNNMYRIMFDRRFESEDDPLFNKLKALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICQEVKDRRLQLFKDFFVQERKLGSTSGASNMELKCAIDHILEAERKGEINEDNWGIAELVNHPEIQRKLRRELDTVLGPGVQITEPDIHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGCDIPAESKILVNAWWLANNPDNWKNPEEFRPERFLEEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQSKIDTTEKGGQFSLHILKHSTIVCKPGLF
>Acat_1g013570
MAIPLLVPHMNLHDAKLGGCDIPAESKILVNAWLARQQPRQLEEPRGVPPREILRGRSQGRSQWQRFRYLPFGFGRRSCPGIILALPILGITIGRLVKNFELLPPPGPEQDRLPPRREGSSVLHILKHSTIVCKPGLFAHDTFIIKEACWKISELKDFVIGQTEIKRARDASIGEPLSLPWMAVIDHNSQLKIHGTCGTRQQKHAITPTRQNLSSRFGYMTNR
>Acat_1g005680
MDLVLLEKALLGLFASVVVAIAISKLRGKRLCLPPGPLPVPVFGNWLQVGDDLNHRNLTALARRFGNILLLRMGQRNLVVVSSPSLAREVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQYRTGWEDEAARVVADVKADPKAATEGIVLRRRLQLMMYNNMYRIMFDRRFESEQDPLFLRLRALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICKELASTKPADNAGLKCAIDHILDAEKKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQQKLRNELDTVLGPGVQITEPDTQKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDIPAESKILVNAWCLANNPDHWKKPEEFRPERFLQEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQKKLDTAEKGGQFSLHILKHSTIVAKPRVF
>Acat_2g013710
MSSLGSKAPIVKLPLPIPVFGNKLRVSDDLNHRNLSTLARCFGNILLLCMGQCNLIVVSSPTLTREVLYT
>Acat_2g013720
MVFTIYGEHWQKMRRIMTIPFFTNKVVQQYRAGWEDEVARVITDVKADPKAVTKGIMLRRRLQLMIYNNMYRIMFDRRFESELDPLFLWLRALNGERSRLAKSFEYNYEDFIPILRPFLRGYLKIYKEVKERRLQLFKDYFLDERKKLASTKPTNNAGLKGKPCRVHLFWSPPAAIGGLPHSMHWYGRPAIDLKLLLSTGVDHQRNRLLPHTSKLCNLETALLLHSPGILHPSSSNSKRGTRPTLISSNNR
>Acat_6g008310
MDLVFVEKALLGLFAAVTLAITLSKLRGKRFKLPPGPLPVPIFGNWLQVGDDLNHRNLTALARRFGDIFLLRMGQRNLVVVSSPEPAREVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNRHGWEDEARRVVEDVEANPKAATEGIVLRRRLQLMMYNNMFRIMFDRRFESEDDPLFNKLKALNGERSRLAQSFEYNYGDFIPILRPFLKGYLKICQEVKDRRLQLFKDYFISERKKLASTKGATSVDLKCAMDHILDAERKGEINEANVLYIVENINTTLWSIEWGIAELVNHQEIQRKLRHELDTVLGPGAQITEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDIPAESKVLVNAWWLANNPDSWKNPEEFRPERFLEEEAKVEANGNDFKYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQSKIDTTEKGGQFSLHILKHSTIVCKPRVL
>Acat_8g007930
MDLVLLEKALLGLFAAIIVAITVSKLRGKRFRLPPGPLSVPVFGNWLQVGDDLNHRNLSALARRFGDILLLRMGQRNLVVVSSPAHAREVLHTQGVEFGSRTRNVVFDIFTGQGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQYRTGWEDEAARVVADVKADPKAATEGIVLRRRLQLMMYNNMYRIMFDRRFESEADPLFLRLRALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICKEVKERRLQLFKDYFLDERKKVASTKPTDNAGLKCAIDHILDAEKKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQQKLRNELDTVLGPGVQVTEPDTYKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDIPAESKILVNAWWLANNPGHWKKPEEFRPERFLEEESKVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPAGQKKLDTSEKGGQFSLHILKHSTIVAKPRVF
>Acat_13g004350
MAVAPGKLALSTLLSLAFILVARSLFPTQLSPIALSIAFLILFISSLFPNSKRSNTPPGPLSLPIFGNWLQVGNDLDHRFLANLSEKYGNVFLLELGARNLVVVSDPKLATEVLHTQGVEFGSRPRNVVFDIFTGNGQDMVFTVYGDHWRKMRRIMTLPFFTNKVVQQYREMWEEEMDLVVQDLAGDDDRIAQEQGMVIRRRLQLMLYNIMYRMMFDARFESAADPLFLEATRFNSERSRLAQSFEYNYGDFIPILRPFLRGYLNKCRDLQSRRLAFFNNYYVEKRRKVMAAGGDRHKPRCAIDHILEAEKNGEITAENVIYIVENINVAAIETTLWSMEWAIAELVNRPAVQEKLRREIADVLKGEAVTESNLQRLPYLQAVVRETLRLHTPIPLLVPHMNLEEAKLGGYTIPEGSKVVVNAWWLANNPAWWDRPEEFRPERFLEEEKAVDAVVGGKVDFRFLPFGVGRRSCPGIILALPILGLILGKLVTNFEMSPPPGVEKIDVSEKGGQFSLHIAKHSVVAFRPIQK
>Acat_14g019800
MAFSMKSVAISTLVSLGFILAAKPLLPIQSLVPISVFLFLASLTLISNSRPSNIPPGPVSIPIFGNWLQVGNDLNHRFLASMAKKYGSVFLLRLGARNLVVVSDPKLATEVLHTQGVEFGSRPRNVVFDIFTGNAQDMVFTVYGEHWRRMRRIMTLPFFTNKVVQQYREMWVEEMDAVVEDLRGNKRAQAEGMVIRRRLQLMLYNIMYRMMFDARFESDSDPLFQQATRFNSERSRLAQSFEYNYGDFIPILRPFLREKNGEITSENVIYIVENINVAAIETTLWSMEWTIAELVNHPTVQDKLRREIVDVLGDEPVTESNLPRLPYLQAVVKETLRLHSPIPLLVPHMNLEEAKLGGYTIPRGSKVVVNAWWLANNPELWDKPEEFRPERFLEEETEVDAAVGGKVDFRFLPFGVGRRSCPGIILALPILGIVVGKLVRNFELVPPPGVDKIDVSEKGGQFSLHIATHSVIAFRPIAA
MDLLLLEKALLGLFAAVTLAIAVSKLRGKRLKLPPGPLPVPIFGNWLQVGDDLNHRNLAALAKRFGDILLLRMGQRNLVVISSPDLAREVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNRHGWEEEARRVVENVKANPKAATEGIVLRRRLQLMMYNNMYRIMFDRRFESEDDPLFNKLKALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICQEVKDRRLQLFKDFFVQERKLGSTSGASNMELKCAIDHILEAERKGEINEDNWGIAELVNHPEIQRKLRRELDTVLGPGVQITEPDIHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGCDIPAESKILVNAWWLANNPDNWKNPEEFRPERFLEEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQSKIDTTEKGGQFSLHILKHSTIVCKPGLF
>Acat_1g013570
MAIPLLVPHMNLHDAKLGGCDIPAESKILVNAWLARQQPRQLEEPRGVPPREILRGRSQGRSQWQRFRYLPFGFGRRSCPGIILALPILGITIGRLVKNFELLPPPGPEQDRLPPRREGSSVLHILKHSTIVCKPGLFAHDTFIIKEACWKISELKDFVIGQTEIKRARDASIGEPLSLPWMAVIDHNSQLKIHGTCGTRQQKHAITPTRQNLSSRFGYMTNR
>Acat_1g005680
MDLVLLEKALLGLFASVVVAIAISKLRGKRLCLPPGPLPVPVFGNWLQVGDDLNHRNLTALARRFGNILLLRMGQRNLVVVSSPSLAREVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQYRTGWEDEAARVVADVKADPKAATEGIVLRRRLQLMMYNNMYRIMFDRRFESEQDPLFLRLRALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICKELASTKPADNAGLKCAIDHILDAEKKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQQKLRNELDTVLGPGVQITEPDTQKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDIPAESKILVNAWCLANNPDHWKKPEEFRPERFLQEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQKKLDTAEKGGQFSLHILKHSTIVAKPRVF
>Acat_2g013710
MSSLGSKAPIVKLPLPIPVFGNKLRVSDDLNHRNLSTLARCFGNILLLCMGQCNLIVVSSPTLTREVLYT
>Acat_2g013720
MVFTIYGEHWQKMRRIMTIPFFTNKVVQQYRAGWEDEVARVITDVKADPKAVTKGIMLRRRLQLMIYNNMYRIMFDRRFESELDPLFLWLRALNGERSRLAKSFEYNYEDFIPILRPFLRGYLKIYKEVKERRLQLFKDYFLDERKKLASTKPTNNAGLKGKPCRVHLFWSPPAAIGGLPHSMHWYGRPAIDLKLLLSTGVDHQRNRLLPHTSKLCNLETALLLHSPGILHPSSSNSKRGTRPTLISSNNR
>Acat_6g008310
MDLVFVEKALLGLFAAVTLAITLSKLRGKRFKLPPGPLPVPIFGNWLQVGDDLNHRNLTALARRFGDIFLLRMGQRNLVVVSSPEPAREVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQNRHGWEDEARRVVEDVEANPKAATEGIVLRRRLQLMMYNNMFRIMFDRRFESEDDPLFNKLKALNGERSRLAQSFEYNYGDFIPILRPFLKGYLKICQEVKDRRLQLFKDYFISERKKLASTKGATSVDLKCAMDHILDAERKGEINEANVLYIVENINTTLWSIEWGIAELVNHQEIQRKLRHELDTVLGPGAQITEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDIPAESKVLVNAWWLANNPDSWKNPEEFRPERFLEEEAKVEANGNDFKYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPPGQSKIDTTEKGGQFSLHILKHSTIVCKPRVL
>Acat_8g007930
MDLVLLEKALLGLFAAIIVAITVSKLRGKRFRLPPGPLSVPVFGNWLQVGDDLNHRNLSALARRFGDILLLRMGQRNLVVVSSPAHAREVLHTQGVEFGSRTRNVVFDIFTGQGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQYRTGWEDEAARVVADVKADPKAATEGIVLRRRLQLMMYNNMYRIMFDRRFESEADPLFLRLRALNGERSRLAQSFEYNYGDFIPILRPFLRGYLKICKEVKERRLQLFKDYFLDERKKVASTKPTDNAGLKCAIDHILDAEKKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQQKLRNELDTVLGPGVQVTEPDTYKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDIPAESKILVNAWWLANNPGHWKKPEEFRPERFLEEESKVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFELLPPAGQKKLDTSEKGGQFSLHILKHSTIVAKPRVF
>Acat_13g004350
MAVAPGKLALSTLLSLAFILVARSLFPTQLSPIALSIAFLILFISSLFPNSKRSNTPPGPLSLPIFGNWLQVGNDLDHRFLANLSEKYGNVFLLELGARNLVVVSDPKLATEVLHTQGVEFGSRPRNVVFDIFTGNGQDMVFTVYGDHWRKMRRIMTLPFFTNKVVQQYREMWEEEMDLVVQDLAGDDDRIAQEQGMVIRRRLQLMLYNIMYRMMFDARFESAADPLFLEATRFNSERSRLAQSFEYNYGDFIPILRPFLRGYLNKCRDLQSRRLAFFNNYYVEKRRKVMAAGGDRHKPRCAIDHILEAEKNGEITAENVIYIVENINVAAIETTLWSMEWAIAELVNRPAVQEKLRREIADVLKGEAVTESNLQRLPYLQAVVRETLRLHTPIPLLVPHMNLEEAKLGGYTIPEGSKVVVNAWWLANNPAWWDRPEEFRPERFLEEEKAVDAVVGGKVDFRFLPFGVGRRSCPGIILALPILGLILGKLVTNFEMSPPPGVEKIDVSEKGGQFSLHIAKHSVVAFRPIQK
>Acat_14g019800
MAFSMKSVAISTLVSLGFILAAKPLLPIQSLVPISVFLFLASLTLISNSRPSNIPPGPVSIPIFGNWLQVGNDLNHRFLASMAKKYGSVFLLRLGARNLVVVSDPKLATEVLHTQGVEFGSRPRNVVFDIFTGNAQDMVFTVYGEHWRRMRRIMTLPFFTNKVVQQYREMWVEEMDAVVEDLRGNKRAQAEGMVIRRRLQLMLYNIMYRMMFDARFESDSDPLFQQATRFNSERSRLAQSFEYNYGDFIPILRPFLREKNGEITSENVIYIVENINVAAIETTLWSMEWTIAELVNHPTVQDKLRREIVDVLGDEPVTESNLPRLPYLQAVVKETLRLHSPIPLLVPHMNLEEAKLGGYTIPRGSKVVVNAWWLANNPELWDKPEEFRPERFLEEETEVDAAVGGKVDFRFLPFGVGRRSCPGIILALPILGIVVGKLVRNFELVPPPGVDKIDVSEKGGQFSLHIATHSVIAFRPIAA
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University