Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Trochodendron aralioides
Species name
Trochodendron aralioides is a species of flowering plant in the family Trochodendraceae.
Species info
Gene sequence info
Trochodendron_aralioides.4CL.fa
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>evm.model.group1.4695
METQTKQQEFIYRSKLPDIYIPNHLPLHSYCFENISEFSSRPCLINGATGEIHTYADVELISRKVAAGLNKLGIQQHQVIMLLLPNSPEFVFAFLGASYLGATTTTANQFYTPAEISKQAKASNARLIITQASYVDKLKDLVQENDVKVICIDSPPEGCLHFSELTQSDENNVPGVKISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFSSDDVVLCVLPLFHIYSLNSVLLCALRVGAAILIMQKFEIVTMMELVQKYKVTIAPFVPPIVLAIAKSPAVDDYDLSSIRTVMSGAAPMGKELEDTLRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGSCGTVVRNAEMKIVDPDTGACLPRKQPGEICIRGAQIMKGYLNDPEATKGTIDQEGWLHTGDVGYIDDDEELFIVDRLKELIKYKGFQVAPAELEAMLLAHPNISDAAVVPMKDDLAGEVPVAFVVKSNGSKIKEDEIKQYISKQVVFYKRINRVFFTEAIPKAPSGKILRKDLRAKLAAGYPK
>evm.model.group3.777
METQTKQQDFIYRSKLPDIYIPNHLPLHSYCFENISQFSSRPCLINGATGEIHTYADVELTARKVATGLHKLGIQQGQVIMLLLPNSPEFVFAFFGASYRGATITTANPFYTAAEISKQAKASNARLIITLACCVEKLKDFAHENDVKIMCIDSPPEGCFHFSELTQSDEKDIPDVKISSDDVVAMPYSSGTTGLPKGVMLSHKGLVTSVAQQVDGENPNLYFHSEDVILCLLPLFHIYSLNSVLLCGLRVGAAILIMQKFEIIALMDLVQKYKVTIAPFVPPIVVDIAKSPVVDNYDLSSIRMVISGAAPLGKELEDTVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKESYDIKAGACGTVVRNAEMKIVEPETGVSLPRNQPGEICIRGAQIMKGYLNDPDSTEKTIDKEGWLHTGDIGYVDEDDEIFIVDRLKELIKYKGFQVAPAELEAMLLAHANISDAAVVPMKDDISGEVPVAFIVRSNGSEITEDDIKQYISKQVVFYKRIKRVFFTDAIPKAPSGKILRKDLRAKLAISVPN
>evm.model.group7.1649
MEKSGYGRYGIYTSLRPPVVFPRDPNLSMVSFLFRNSSSYSNHLALIDADSSDSLTFNQFKSMVAKVARGLIQLGIKKGDVVLIFAPNSIKFPLCFLGIVALGAIATTVNPLYTVAELSKQVKDSGPKLVITVPELWDKVKDLGLPAVILESSSSSSIVLNAGITYFSDLVKMAGPMMDFPAVSVKQTDTAALLYSSGTTGTSKGVILTHRNFIAASIMANADQDFEGQGHNIFLCFLPMFHIFGLSIITYAQLQRGNTVVSMARFDIEKVLRSIEKYKVTHLFVVPPVMIALAKRSAVKNYDLSSLKQLGSGAAPLGKDIMEECAKNFPQAAIVQGYGMTETCGIVSLENPKEGTRHSGSTGSLVPGVESQIVSVDTLKSLPPNQLGEIWVRGPNMMQGYFNNPQATKLTIDKQGWVHTGDLGYFNEEGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHSEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEEDVQKFIAKQVAPFKRLRRVTFINTVPKSASGKILRRELIEKVRAKL
>evm.model.group8.1795
MYSEGGGIGRDSGTNGEVQLPRDAECSGSVSGDIHAGVATTCGGDDEVRALEVVGKYDLSSLQVLGCGGAPLGKEVSERFMARFPNVEIVDSAGKRIDMTVQVGYGLTETTGGASKLLRPDECKRYGPYGSVGVLSENMEAMIVDPVSGEALPPEQQGELWLRGPTIMKEGWLKTGDLCYFDSDGYLFIVDRLKALIKYKAYQVLILVRKLEKHMVVAVVSVPLKVPPAELEHLLQSHPEIADAAVIPYASDGFIFYQCA
>evm.model.group10.50
MGTHIQDSLEDEQHIFSSRFPAVPVPENMTLPEFVLRDAELYADKVAFVQDVTGKEYTYGQVVRDTKRFAKALRSLGLRKGGVVVVLLPNVAEYAIIALGIMAAGGVFSGANPSAHASEIKKQVEDADAKLIVTNGSTYEKVKGLVVPVIVVGEERVASAISWDGLLEAADRAGTDTVNETINQTDLCALPFSSGTTGTSKGVMLTHRNLVANLCSTLFSVGSDMVGQITTLGLIPFFHIYGITGICCATLRNKGKVVVMGRFELRMFLNALISYEVNFAPIVPPIMLALVKNPVVDEFDLAKLKLKAVMTAAAPLAPELLTAFEKKFPGVQVQEAYGLTEHSCITLTHGDPSKGHGIAKKNSVGFILPNLEIKFIDPDTGRSLPIDTTGEVCVRSQCVMQGYYKNKEETDRTIDSKGWLHTGDIGYIDNDGDVFIVDRIKELIKFKGFQVAPAELEAILLSHPSVEDAAVVPLPDEEAGEIPAACVVMNPDAKESEEEVMEYVASNVASYKRVRVVQFVDTIPKSPSGKIMRRFLRDKMVKKMDTKPSTASHCFSSTA
>evm.model.group15.220
MMSLASPETHPPQISPKIPLAENPSSENHVFKSKLPDIPISNHLPLHTYCFENVSEFSERPCLITGSNGRTYSFAETHLLCQKTAAGFSKLGIKKGDVIMLLLQNCPEFVFSFMGASMIGAFTTTANPFYTPAEIFKQISSSGTKLVVTQSQYVDKLLDSTEKKFPKMGNDFTVITVDDPPENCLHFSVISSADESEIPSVSIDSNDPVALPFSSGTTGLPKGVLLTHKSLISSIAQQVDGENPNLYLKSDDIVLCVLPLFHIYSLNSVLLCSLRAGAGVLLMQKFEIGALLELIQRYRVSVAPVVPPLVLALAKNPMVETFDLSSIRFVLSGAAPLGKELEQALRTRVPHAVLGQGYGMTEAGPVLSMCLGFAKQPIPTKSGSCGTVVRNAELKVIDPDNGFSLGYNQPGEICIRGPQIMKGYLNDTEATATTIDVEGWLHTGDIGYIDDDEEIFIVDRVKELIKFKGFQVPPAELEALLVSHPSIADAAVVPQKDAVSGEVPVAFVVRSNTSELTEEAVKEFIAKQVVFYKKLHTVHFVHAIPKSPSGKILRKDLRAKLASAST
>evm.model.group18.667
MEKSGYGSDGIYRSLRPPVVFPTDPNLSMVSFLFRNSPSYSDHLALIDADSDETLTFYQFKSMVAKVAHGLIQLGIKKGDVVLIFAPNSIRFPLCFLGVIALGAIATTVNPLYTVAELSKQVKDSGPKLVITVPELWDKVKGFGIPSVILGSSSSSSIVSNARITYFSDLVKMADSISDFPAVSVKQSDIAALLYSSGTTGTSKGVILTHRNFIAASIMAASDQDFEGQGHNIFLCFLPMFHIFGLSIITYAQLQRGNTVVSMGKFDIGKVLRSIEKYKVTHMFVVPPVIIALAKLNVVKNYDLSSLKMLGSGAAPLGKDIMEECAKNFPQAAVIQGYGMTETCGIISLENQREGTRHSGSTGTLVPGVESQIVSVETLKPLPPNQLGEIWVRGPNMMKGYFNNPQATKLTIDKQGWVHTGDLGYFNEESQLFVVDRIKELIKCKGYQVAPAELEGLLISHPEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEEDIQKFIAKQVAPFKRLRRVTFINTVPKSASGKILRRELIDKVRSKL
>evm.model.contig818.2
MAGPTPLPKPIFSARKPAAGFSKLGIKKGDVIMLLLQNCPEFVFSFMGASMIGAFTTTANPFYTPAEIFKQISSSGTKLVVTQSQYVDKLLDSTEKKFPKMGNDFTVITVDDPPENCLHFSVISSADESEIPSVSIDSNDPVALPFSSGTTGLPKGVIVDPQELDF
>evm.model.contig818.3
MQKFEIGALLELIQRYRVSVAPVVPPLVLALAKNPMVETFDLSSIRFVLSGAAPLGKELEQALRTRVPHAVLGQGYGMTEAGPVLSMCLGFAKQPIPTKSGSCGTVVRNAELKVIDPDNGFSLGYNQPGEICIRGPQIMKGYLNDTEATATTIDVEGWLHTGDIGYIDDDEEIFIVDRVKELIKFKGFQVPPAELEALLVSHPSIADAAVVPQKDAVSGEVPVAFVVRSSTSELTEEAVKEFIAKQVRDIKYIFFYC
METQTKQQEFIYRSKLPDIYIPNHLPLHSYCFENISEFSSRPCLINGATGEIHTYADVELISRKVAAGLNKLGIQQHQVIMLLLPNSPEFVFAFLGASYLGATTTTANQFYTPAEISKQAKASNARLIITQASYVDKLKDLVQENDVKVICIDSPPEGCLHFSELTQSDENNVPGVKISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFSSDDVVLCVLPLFHIYSLNSVLLCALRVGAAILIMQKFEIVTMMELVQKYKVTIAPFVPPIVLAIAKSPAVDDYDLSSIRTVMSGAAPMGKELEDTLRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGSCGTVVRNAEMKIVDPDTGACLPRKQPGEICIRGAQIMKGYLNDPEATKGTIDQEGWLHTGDVGYIDDDEELFIVDRLKELIKYKGFQVAPAELEAMLLAHPNISDAAVVPMKDDLAGEVPVAFVVKSNGSKIKEDEIKQYISKQVVFYKRINRVFFTEAIPKAPSGKILRKDLRAKLAAGYPK
>evm.model.group3.777
METQTKQQDFIYRSKLPDIYIPNHLPLHSYCFENISQFSSRPCLINGATGEIHTYADVELTARKVATGLHKLGIQQGQVIMLLLPNSPEFVFAFFGASYRGATITTANPFYTAAEISKQAKASNARLIITLACCVEKLKDFAHENDVKIMCIDSPPEGCFHFSELTQSDEKDIPDVKISSDDVVAMPYSSGTTGLPKGVMLSHKGLVTSVAQQVDGENPNLYFHSEDVILCLLPLFHIYSLNSVLLCGLRVGAAILIMQKFEIIALMDLVQKYKVTIAPFVPPIVVDIAKSPVVDNYDLSSIRMVISGAAPLGKELEDTVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKESYDIKAGACGTVVRNAEMKIVEPETGVSLPRNQPGEICIRGAQIMKGYLNDPDSTEKTIDKEGWLHTGDIGYVDEDDEIFIVDRLKELIKYKGFQVAPAELEAMLLAHANISDAAVVPMKDDISGEVPVAFIVRSNGSEITEDDIKQYISKQVVFYKRIKRVFFTDAIPKAPSGKILRKDLRAKLAISVPN
>evm.model.group7.1649
MEKSGYGRYGIYTSLRPPVVFPRDPNLSMVSFLFRNSSSYSNHLALIDADSSDSLTFNQFKSMVAKVARGLIQLGIKKGDVVLIFAPNSIKFPLCFLGIVALGAIATTVNPLYTVAELSKQVKDSGPKLVITVPELWDKVKDLGLPAVILESSSSSSIVLNAGITYFSDLVKMAGPMMDFPAVSVKQTDTAALLYSSGTTGTSKGVILTHRNFIAASIMANADQDFEGQGHNIFLCFLPMFHIFGLSIITYAQLQRGNTVVSMARFDIEKVLRSIEKYKVTHLFVVPPVMIALAKRSAVKNYDLSSLKQLGSGAAPLGKDIMEECAKNFPQAAIVQGYGMTETCGIVSLENPKEGTRHSGSTGSLVPGVESQIVSVDTLKSLPPNQLGEIWVRGPNMMQGYFNNPQATKLTIDKQGWVHTGDLGYFNEEGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHSEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEEDVQKFIAKQVAPFKRLRRVTFINTVPKSASGKILRRELIEKVRAKL
>evm.model.group8.1795
MYSEGGGIGRDSGTNGEVQLPRDAECSGSVSGDIHAGVATTCGGDDEVRALEVVGKYDLSSLQVLGCGGAPLGKEVSERFMARFPNVEIVDSAGKRIDMTVQVGYGLTETTGGASKLLRPDECKRYGPYGSVGVLSENMEAMIVDPVSGEALPPEQQGELWLRGPTIMKEGWLKTGDLCYFDSDGYLFIVDRLKALIKYKAYQVLILVRKLEKHMVVAVVSVPLKVPPAELEHLLQSHPEIADAAVIPYASDGFIFYQCA
>evm.model.group10.50
MGTHIQDSLEDEQHIFSSRFPAVPVPENMTLPEFVLRDAELYADKVAFVQDVTGKEYTYGQVVRDTKRFAKALRSLGLRKGGVVVVLLPNVAEYAIIALGIMAAGGVFSGANPSAHASEIKKQVEDADAKLIVTNGSTYEKVKGLVVPVIVVGEERVASAISWDGLLEAADRAGTDTVNETINQTDLCALPFSSGTTGTSKGVMLTHRNLVANLCSTLFSVGSDMVGQITTLGLIPFFHIYGITGICCATLRNKGKVVVMGRFELRMFLNALISYEVNFAPIVPPIMLALVKNPVVDEFDLAKLKLKAVMTAAAPLAPELLTAFEKKFPGVQVQEAYGLTEHSCITLTHGDPSKGHGIAKKNSVGFILPNLEIKFIDPDTGRSLPIDTTGEVCVRSQCVMQGYYKNKEETDRTIDSKGWLHTGDIGYIDNDGDVFIVDRIKELIKFKGFQVAPAELEAILLSHPSVEDAAVVPLPDEEAGEIPAACVVMNPDAKESEEEVMEYVASNVASYKRVRVVQFVDTIPKSPSGKIMRRFLRDKMVKKMDTKPSTASHCFSSTA
>evm.model.group15.220
MMSLASPETHPPQISPKIPLAENPSSENHVFKSKLPDIPISNHLPLHTYCFENVSEFSERPCLITGSNGRTYSFAETHLLCQKTAAGFSKLGIKKGDVIMLLLQNCPEFVFSFMGASMIGAFTTTANPFYTPAEIFKQISSSGTKLVVTQSQYVDKLLDSTEKKFPKMGNDFTVITVDDPPENCLHFSVISSADESEIPSVSIDSNDPVALPFSSGTTGLPKGVLLTHKSLISSIAQQVDGENPNLYLKSDDIVLCVLPLFHIYSLNSVLLCSLRAGAGVLLMQKFEIGALLELIQRYRVSVAPVVPPLVLALAKNPMVETFDLSSIRFVLSGAAPLGKELEQALRTRVPHAVLGQGYGMTEAGPVLSMCLGFAKQPIPTKSGSCGTVVRNAELKVIDPDNGFSLGYNQPGEICIRGPQIMKGYLNDTEATATTIDVEGWLHTGDIGYIDDDEEIFIVDRVKELIKFKGFQVPPAELEALLVSHPSIADAAVVPQKDAVSGEVPVAFVVRSNTSELTEEAVKEFIAKQVVFYKKLHTVHFVHAIPKSPSGKILRKDLRAKLASAST
>evm.model.group18.667
MEKSGYGSDGIYRSLRPPVVFPTDPNLSMVSFLFRNSPSYSDHLALIDADSDETLTFYQFKSMVAKVAHGLIQLGIKKGDVVLIFAPNSIRFPLCFLGVIALGAIATTVNPLYTVAELSKQVKDSGPKLVITVPELWDKVKGFGIPSVILGSSSSSSIVSNARITYFSDLVKMADSISDFPAVSVKQSDIAALLYSSGTTGTSKGVILTHRNFIAASIMAASDQDFEGQGHNIFLCFLPMFHIFGLSIITYAQLQRGNTVVSMGKFDIGKVLRSIEKYKVTHMFVVPPVIIALAKLNVVKNYDLSSLKMLGSGAAPLGKDIMEECAKNFPQAAVIQGYGMTETCGIISLENQREGTRHSGSTGTLVPGVESQIVSVETLKPLPPNQLGEIWVRGPNMMKGYFNNPQATKLTIDKQGWVHTGDLGYFNEESQLFVVDRIKELIKCKGYQVAPAELEGLLISHPEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEEDIQKFIAKQVAPFKRLRRVTFINTVPKSASGKILRRELIDKVRSKL
>evm.model.contig818.2
MAGPTPLPKPIFSARKPAAGFSKLGIKKGDVIMLLLQNCPEFVFSFMGASMIGAFTTTANPFYTPAEIFKQISSSGTKLVVTQSQYVDKLLDSTEKKFPKMGNDFTVITVDDPPENCLHFSVISSADESEIPSVSIDSNDPVALPFSSGTTGLPKGVIVDPQELDF
>evm.model.contig818.3
MQKFEIGALLELIQRYRVSVAPVVPPLVLALAKNPMVETFDLSSIRFVLSGAAPLGKELEQALRTRVPHAVLGQGYGMTEAGPVLSMCLGFAKQPIPTKSGSCGTVVRNAELKVIDPDNGFSLGYNQPGEICIRGPQIMKGYLNDTEATATTIDVEGWLHTGDIGYIDDDEEIFIVDRVKELIKFKGFQVPPAELEALLVSHPSIADAAVVPQKDAVSGEVPVAFVVRSSTSELTEEAVKEFIAKQVRDIKYIFFYC
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University