Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Tripterygium wilfordii
Species name
Tripterygium wilfordii is a species of eudicot in the family Celastraceae (bittersweet family).
Species info
Gene sequence info
Tripterygium_wilfordii.CHS.fa
Download
>rna-XM_038854595.1
MGSGETAQVFSTKKANPGKATILALGKAFPHQLVMQEFLVDGYFKNTNCDDPELKEKLTRLCKTTTVKTRYVVMSEEILKKYPELAVEGLPTVKQRLDICNNAVTQMAIEASQACIKNWGRSLSDITHIVYVSSSEVRLPGGDLYLARGLGISPETQRVMLYFSGCSGGVAGIRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGTDPVQGTERPLFELHTAIQNFLPNTEKTIDGKLTEEGISFKLARELPQIIEDHIEGFCDKLMRVIGLTDKEYNKMFWAVHPGGPAILNRMEKRLDLLPEKLNASRRALMDYGNASSNTIVYVLEYMIEEEGLKIKGNQEDSEWGLILAFGPGITFEGILARNLTV
>rna-XM_038844329.1
MATCRAQGVASILAIGTANPPNCFYQADYPDFYFGITQSEHMTQLKEKFKRICEKTTIIKRYMYLNEDIIRENPSIATSNAPSLDSRQEILVPEVPKLGKEAAVKAIKEWGKPISRITHLIFCTSSGIIMPGADFRLTQLLGLNPSVKRFMLYQSGCFAGAASLRLAKDIAENNVGSRILIVCSENMVTSFHAPSETHLDILVGSAIFSDGAAAVIVGADPVLDSEHPLFELVSASQTIIPDSEDGIIGEVREIGMKYYLSKGLSEIIARKIQQCMVENFTPLGINDWNSLFYIVHPGGPAVLRVVEENLGLSKGKLKASWHVLQEYGNMWSAGVLFVLDEIRKKSMKEGKPTTGEGLNLGALFGFGPGVTVETVVLRSVAIDSPFSSIA
>rna-XM_038849582.1
MCTKSLQNGLSENLASQLLFSNPYILCKICWHHNSLSAYYSTLIMQHSTVYIQSSHTLVLQVEGVEKTIALRIRRDMGSGEIAQVCSTKKANPGKAAILALGKAFPHQLVMQEFLVDGYFKNTNCEDPELKEKLTRLCKTTTVKTRYVVMSEEILKKYPELAVEGLPTVKQRLDICNNAVTQMAVEASQACIKNWGRSLSDITHIVYVSSSEARLPGGDLYLARELGISPETKRVMLYFSGCSGGVAGIRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGTGPVPGTERPLFELHTAIQNFLPNTEKTIDGKLTEEGISFKLARDLPQIIEDHIEGFCDKLMRVVGLTDKEYNKMFWAVHPGGPAILNRMEKRLDLLPEKLNASRRALMDYGNASSNTIVYVLEYMIEESLKMKGNQEDSEWGLILAFGPGITFEGILARNLTV
>rna-XM_038864630.1
MVTVDEVRKAQRAEGPATIMAIGTATPPNCVDQSAYPDYYFRITNSEHKTELKEKFRRMCDKSMIKKRYMYLTEEILKENPSMCEYMAPSLDARQDMVVVEVPKLGKEAATKAIKQWGQPKSKITHLVFCTTSGVDMPGCDYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPNDTHLDSLVGQALFGDGAAAIIVGSDPIPDVERPLFELVWTAQTILPDSHGAIDGHLREVGLTFHLLKDVPGLISKNIGKSMEEAFKPLNISDWNSLFWIAHPGGPAILDQVEEKLGLKPEKLRATRQVLSDYGNMSSACVLFILDEMRRKSAEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVAT
>rna-XM_038867427.1
MVTVDEVRKAQRAEGPATIMAIGTATPPNCVDQSAYPNYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMYLTEDILKENPSMCEYMAPSLDARQDMVVVEVPKLGKEAATKAIKQWGQPKSKITHLVFCTTSGVDMPGCDYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIVGSDPVPGVERPLYELVSTAQTILPDSHGAIDGHLREVGLTFHLLKDVPGLISKNIAKSLEEAFQPLNISDWNSLFWIAHPGGRPILDQVEEKLGLKPEKLRATRQVLSDYGNMSSACVLFILDEMRKKSAEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVAN
>rna-XM_038825725.1
MSRADNNGVPKHYPGHARRTPTPGKATILALGKAFPRQLIPQDCLVEGYVRDTKCEDASIKEKLERLCKTTTVKTRYTVLSKDILDKYPELATEGSSTIKQRLDIANPAVVEMALEASLACIEEWGRPAEDITHIVYVSSSEIRLPGGDLYLASQLGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAAIIGTNPITGRESPFMELNYAVQQFLPGTQNVIDGHLSEEGINFKLGRDLPQKIDENIEDFCKKLMSKAGLKEFNDLFWAVHPGGPAILNRLESTLKLKAQKLECGRRALMNYGNVSSNTIFYVMDYMRDELKREGGEEWGLALAFGPGITFEGILIRSL
>rna-XM_038828187.1
MAALSSSHSRAELLSLSLSQLLKHRGSTDLNLLPSSLRFFSTQKIRGKHGVENDEDSDGGEELDGRKFKPKRSSTKTKRAKSMARLINTKPWSRDLESSLASLAPSPSKTTVVQTLHFINSLPKAMQFFDWVQKIGFTHDQQSYFFMLEILGRARNLNVARNFLNSIERRSNGVVKLEDKFFNSLIRSYGRAGLFQEACKVFEMMKAIGVSPSVFSFNSLLLILLKRGRTNMAKSLFDEMLKTYGVTPDTYTFNILIRGFCKNSMVEEGFRFFKEMRKFNCDADVITYNTLVDGMCRAGKVRIAHNLVKGMDKRDVDLSPNVVTYTTLIRGYCMKQEIDAALDVFREMVDRGLKPNEITYNTLVKGLSEVQEIDKLKELLAGKIGGGVFTPDTCTFNTLMDAQCNAGNLNEALKIFEKMLELHVQPDSASYSALIRNLCQKGDFERAEELFDELSEKEILLRDLRCRPLVAAFNPMFEYLCRNGKTMKAEKVFRQLMKSGKQDPPSYKTLIMGHCREATFQAGYDLLVLMLRRDFVPDYETYQSLIDGLLQKGEPILAYRALESMLKSCHLPATFTFHSVLAELLKRSCASESASSILLMLETRIRQNIYLSTQTVRLLFSCGKRDKAYQIVGLLYDNGFMVEMGELIDFLFLSKRLFDAYKMLLFSLEKHQTTDVKMCSTVIEGLCKSKRLCEAFALYYELVEKGIHQQLSCIEELRIALHAGGKFEEANFVSKRLQTHWLSDNSEQISSEIHRHQSMYKPKVCRHRKGVSDERFLIRSGVSSLVALVCLLQYVVLHFLDNSVFSNILMLHAVGLGMLDDFYYEIPFECMRLVLGIKTDSVALAQENGWGKTLDTLSSLTPTSLQDLANLSFICPFVKSPTISSAYFPSSLLLNLLKMLRTDNNGVSKHYPVHIRRTPTPGKATVLALGKAFPKQLIPQDCLVEGYIHDTKCEDASIKEKLERLCKITTVKTRYTVMSKDILDKYPELATEGSPTIKQRLEIANPAVVEMALEASIACIKEWGRPVEDITHIVYVSSSEIRLPGGDLYLASQLGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGYRPPNKARPYDLVGAALFGDGAAAAIIGTNPLTRTESPFMELHYAVQQFLPGTQNVIDGRLSEEGIHFKLGRDLPQKIDENIEDFCKKLMSKAGLKEFNDLFWAVHPGGPAILNRLEITLELNAQKLECSRRALMDYGNVSSNTIFYVMDYMREKLKRDGSEEWGLALAFGPGITFEGILVRSL
MGSGETAQVFSTKKANPGKATILALGKAFPHQLVMQEFLVDGYFKNTNCDDPELKEKLTRLCKTTTVKTRYVVMSEEILKKYPELAVEGLPTVKQRLDICNNAVTQMAIEASQACIKNWGRSLSDITHIVYVSSSEVRLPGGDLYLARGLGISPETQRVMLYFSGCSGGVAGIRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGTDPVQGTERPLFELHTAIQNFLPNTEKTIDGKLTEEGISFKLARELPQIIEDHIEGFCDKLMRVIGLTDKEYNKMFWAVHPGGPAILNRMEKRLDLLPEKLNASRRALMDYGNASSNTIVYVLEYMIEEEGLKIKGNQEDSEWGLILAFGPGITFEGILARNLTV
>rna-XM_038844329.1
MATCRAQGVASILAIGTANPPNCFYQADYPDFYFGITQSEHMTQLKEKFKRICEKTTIIKRYMYLNEDIIRENPSIATSNAPSLDSRQEILVPEVPKLGKEAAVKAIKEWGKPISRITHLIFCTSSGIIMPGADFRLTQLLGLNPSVKRFMLYQSGCFAGAASLRLAKDIAENNVGSRILIVCSENMVTSFHAPSETHLDILVGSAIFSDGAAAVIVGADPVLDSEHPLFELVSASQTIIPDSEDGIIGEVREIGMKYYLSKGLSEIIARKIQQCMVENFTPLGINDWNSLFYIVHPGGPAVLRVVEENLGLSKGKLKASWHVLQEYGNMWSAGVLFVLDEIRKKSMKEGKPTTGEGLNLGALFGFGPGVTVETVVLRSVAIDSPFSSIA
>rna-XM_038849582.1
MCTKSLQNGLSENLASQLLFSNPYILCKICWHHNSLSAYYSTLIMQHSTVYIQSSHTLVLQVEGVEKTIALRIRRDMGSGEIAQVCSTKKANPGKAAILALGKAFPHQLVMQEFLVDGYFKNTNCEDPELKEKLTRLCKTTTVKTRYVVMSEEILKKYPELAVEGLPTVKQRLDICNNAVTQMAVEASQACIKNWGRSLSDITHIVYVSSSEARLPGGDLYLARELGISPETKRVMLYFSGCSGGVAGIRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGTGPVPGTERPLFELHTAIQNFLPNTEKTIDGKLTEEGISFKLARDLPQIIEDHIEGFCDKLMRVVGLTDKEYNKMFWAVHPGGPAILNRMEKRLDLLPEKLNASRRALMDYGNASSNTIVYVLEYMIEESLKMKGNQEDSEWGLILAFGPGITFEGILARNLTV
>rna-XM_038864630.1
MVTVDEVRKAQRAEGPATIMAIGTATPPNCVDQSAYPDYYFRITNSEHKTELKEKFRRMCDKSMIKKRYMYLTEEILKENPSMCEYMAPSLDARQDMVVVEVPKLGKEAATKAIKQWGQPKSKITHLVFCTTSGVDMPGCDYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPNDTHLDSLVGQALFGDGAAAIIVGSDPIPDVERPLFELVWTAQTILPDSHGAIDGHLREVGLTFHLLKDVPGLISKNIGKSMEEAFKPLNISDWNSLFWIAHPGGPAILDQVEEKLGLKPEKLRATRQVLSDYGNMSSACVLFILDEMRRKSAEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVAT
>rna-XM_038867427.1
MVTVDEVRKAQRAEGPATIMAIGTATPPNCVDQSAYPNYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMYLTEDILKENPSMCEYMAPSLDARQDMVVVEVPKLGKEAATKAIKQWGQPKSKITHLVFCTTSGVDMPGCDYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIVGSDPVPGVERPLYELVSTAQTILPDSHGAIDGHLREVGLTFHLLKDVPGLISKNIAKSLEEAFQPLNISDWNSLFWIAHPGGRPILDQVEEKLGLKPEKLRATRQVLSDYGNMSSACVLFILDEMRKKSAEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVAN
>rna-XM_038825725.1
MSRADNNGVPKHYPGHARRTPTPGKATILALGKAFPRQLIPQDCLVEGYVRDTKCEDASIKEKLERLCKTTTVKTRYTVLSKDILDKYPELATEGSSTIKQRLDIANPAVVEMALEASLACIEEWGRPAEDITHIVYVSSSEIRLPGGDLYLASQLGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAAIIGTNPITGRESPFMELNYAVQQFLPGTQNVIDGHLSEEGINFKLGRDLPQKIDENIEDFCKKLMSKAGLKEFNDLFWAVHPGGPAILNRLESTLKLKAQKLECGRRALMNYGNVSSNTIFYVMDYMRDELKREGGEEWGLALAFGPGITFEGILIRSL
>rna-XM_038828187.1
MAALSSSHSRAELLSLSLSQLLKHRGSTDLNLLPSSLRFFSTQKIRGKHGVENDEDSDGGEELDGRKFKPKRSSTKTKRAKSMARLINTKPWSRDLESSLASLAPSPSKTTVVQTLHFINSLPKAMQFFDWVQKIGFTHDQQSYFFMLEILGRARNLNVARNFLNSIERRSNGVVKLEDKFFNSLIRSYGRAGLFQEACKVFEMMKAIGVSPSVFSFNSLLLILLKRGRTNMAKSLFDEMLKTYGVTPDTYTFNILIRGFCKNSMVEEGFRFFKEMRKFNCDADVITYNTLVDGMCRAGKVRIAHNLVKGMDKRDVDLSPNVVTYTTLIRGYCMKQEIDAALDVFREMVDRGLKPNEITYNTLVKGLSEVQEIDKLKELLAGKIGGGVFTPDTCTFNTLMDAQCNAGNLNEALKIFEKMLELHVQPDSASYSALIRNLCQKGDFERAEELFDELSEKEILLRDLRCRPLVAAFNPMFEYLCRNGKTMKAEKVFRQLMKSGKQDPPSYKTLIMGHCREATFQAGYDLLVLMLRRDFVPDYETYQSLIDGLLQKGEPILAYRALESMLKSCHLPATFTFHSVLAELLKRSCASESASSILLMLETRIRQNIYLSTQTVRLLFSCGKRDKAYQIVGLLYDNGFMVEMGELIDFLFLSKRLFDAYKMLLFSLEKHQTTDVKMCSTVIEGLCKSKRLCEAFALYYELVEKGIHQQLSCIEELRIALHAGGKFEEANFVSKRLQTHWLSDNSEQISSEIHRHQSMYKPKVCRHRKGVSDERFLIRSGVSSLVALVCLLQYVVLHFLDNSVFSNILMLHAVGLGMLDDFYYEIPFECMRLVLGIKTDSVALAQENGWGKTLDTLSSLTPTSLQDLANLSFICPFVKSPTISSAYFPSSLLLNLLKMLRTDNNGVSKHYPVHIRRTPTPGKATVLALGKAFPKQLIPQDCLVEGYIHDTKCEDASIKEKLERLCKITTVKTRYTVMSKDILDKYPELATEGSPTIKQRLEIANPAVVEMALEASIACIKEWGRPVEDITHIVYVSSSEIRLPGGDLYLASQLGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGYRPPNKARPYDLVGAALFGDGAAAAIIGTNPLTRTESPFMELHYAVQQFLPGTQNVIDGRLSEEGIHFKLGRDLPQKIDENIEDFCKKLMSKAGLKEFNDLFWAVHPGGPAILNRLEITLELNAQKLECSRRALMDYGNVSSNTIFYVMDYMREKLKRDGSEEWGLALAFGPGITFEGILVRSL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University