Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Trichosanthes anguina
Species name
Trichosanthes anguina is a species of eudicot in the family Cucurbitaceae (cucumber family).
Species info
Gene sequence info
Trichosanthes_anguina.HIDH.fa
Download
>Tan0001069.1
MLYTYIFFQPYNFPFPFFKLFSVFFIPSSSLKKSDMAAADSNNPELELELELELFPYLRLYKNGVVQRLVGTRVTPPGLDPLTGVDSKDIIIVPETGVSARLYRPPAVHPRRKLPLVVYFHGGAFLITSSAEPIYHNNCLIPLAAATESVVVSVNYRLAPEHPLPAAYDDSWAALEWIAEQSQFSGDDAGQEPWLKQLVDFEKVFLVGDSAGANISHHMALRAKNSDVAGKIKIVGIGLIQPYFWGEEPIGSEIREPEKKALVDGWWNFVCPSDKGNDDLLINPFADGSPAIEGLAGEKVVVIVAEKDILRERGKLYYENLAKSDWKGKVEFFETEGEDHAFQLLDPNSEKAKSLLKRLASFVNNED
>Tan0007791.1
MAAVDSNIPELDLELLPYLRLYKNGVVERLAGTRVTPPGLDPLSGVHSKDIIIVPETGVSARLYRPTTAFDPRRKLPLVVYFHGGAFLIASSADPVYHNNCLIPLVAQAQTVVVSVNYRLAPEHPLPAAYDDSWAALQWIAAQSQSSDDQPAHEPWLKQHVDFEKVFLVGDSAGANISHHMGLRAQNSDLAGKIKIIGIALIHPYFWGQEPIGSEITEPEKKALVDRWWNFVCPSDRGNDDLLINPFADGSPAIEGLAGEKVVVIVAEKDILKNRGKLYYENLAKSEWKGNVEIFETEGEDHVFHIFDPTSEKAKILIKRLALFVNED
>Tan0018850.1
MALIGEAPGYLEVYSDGSVRRSIPEVIASSETQSSKNYKFKDVITDPKKPVTGRLFLPDITNAATKLPVLVYFHGGGFCIGSTTWIGYHHFLGDLAAASQSVILSVDYRLAPENRLPAAYEDCYSSLEWLSHQSSSEPWLQNADLSRVFLSGDSAGGNIVHHVAVKTIKCNISNLTIKGLLLIHPYFGSEKRTEKEKAQGAEGFVEMNDMFWRLSIPEGQDREYFGCNYENVPITNEEWSEFPSVVVFVAGLDFLKERGELYAKFLQQMKVKEVKLVEAAEESHIFHVFHPESEATRLLQKQMSQFMKSY
>Tan0019739.1
MDSSEPEIVIELLPLLRVYKNGRIERFIGTDFVPPSTDPLTGVTSKDVTILPESGVSARLFLPNLTHPTQRLPLVVYFHGGCFCTQSPFTAKFHNYLNALTAEARVVAVSVNYSKAPEHPIPAAYEDSWAALQWAISHRDREGPEIWLNKHVDFRRVFLAGVSAGANIAHNLAMVAGDPDCGVNIELTGVALEHPYFWGSVRIGKEAGDPVRAELFDRLWEFICPARPENDDPWVNPVAEGAARLARMRSGRVLVCVAEKDVLRDRGRLYYEALGDSGWMGVAEIVETEDEDHMFHLNDLEGQKAKDLIRRLGAFFNRDMPPSLLL
>Tan0002446.1
MTIGKNLILDVSGWLRLFDDGSVDRTWTGPPEVKFVAESVPPHDEFIDGVAVRDVVIDRKSGLRVRIYLPELKCGDGKKLPIVVHFHGGGFCISEADWFMYYHTYTGLVKSAEAICVSVYLRRAPEHRLPAALDDALSALRWLQSVALGDEIEPWITVNADFNRVFLIGDSSGGNLVHSVAALAGDADLAPLKLAGGIPIHPGFVRAKRSKSEMENPQSPFLTLDMVDKFLSLALPTGSSKDHPITCPMGTDAPPLESLNLPPFLLCIAEKDLIIDTEMEYYEAMKAANKEVEILMSKGMGHSFYLNKIALKIDPETAAESDHLFTGIARFIQQH
>Tan0014528.1
MKFKRMAAMYMDPRHKLQMPKLHLQNGVTSEEIEGLIRVYADGHVERPPIIPNVSCSPTASDKGVTAKDVLIDNFTNTWARIYIPNSQRNLPLLVYFHGGGFCVGSAAWSCYHEFLLNLASKTKCVILSINYRLSPENRLPAAYEDGFNALMWLKQQALTDPIEHKWWLGNCKPSKLFLAGDSAGANIAYNIATRLGLNESPILKPLTLKGIILIQPFFGGESRTKSEKLAAQFSSASALTLPTADTYWRLSLPPAANRDHPWSNPLVNGGAKLRETKLPPLMVCISELDILLDRNLEFCAAMAAAGKKVERVILKGVGHCFQILNKDQISTLRTQEMMGSIQAFILHQ
>Tan0004627.1
MRRKRMPTINLDQIPSFEEHVNGFKQHDVLVEEIEGLIRVYGNGYVERAQIVPCVSNALQPELGVTSWDVVVDKLNNIWARFYIPQQCQEKLPLLVYFHGGGFCVGSAAWSCYHEFLAKLSAKADCIIMSVNYRLAPENPLPAPYEDGLKILSWLKQVALVGAKQNWWSRYCDFTRIFLGGDSAGGNIAFNVAARVGGKTTASGAVVLKPLVIKGNILIQPFFGGESRTKSEKFLVQPPRSALTMAVSDTYWRLALPSGANRDHPWCNPSANGLFKVEDLRALPSLVCISEMDILKDRNLDFCSALHRAGKLVNYVVYEGVGHAFQVLNKSQLSQTRTLEMIDHIKDFLSV
>Tan0000342.1
MASNEIALNAAPWFVIYKDGRIDRLIGNDIDPPGLDPKTGVDSKDVVISPEDSVTVRIYRPKSTAAAGKQAQKLPLLVYFHGGGFCIETAFSPFYHQHINPWVAEANIVAVSVDYRRAPEHQLPIPFEDSWTALKWIAAHSNGTGPDEWLNEIADLNQVYLAGDSAGGNIAHRMALRAGTEGLAGVKIRGLQLIHPHFWGEKLIGEEKEWDPKDIFVVENLWYLVSKDIKGLDDPIVNPEHDPDLGRLAAERVAVYVAEKDNLKVRGRHYAECLRKSGWGGEIEVVETDGEGHVFHLFNPTCDSAADLVGQLAAFISGGRRG
>Tan0002801.1
MASNEIAHNFTPMLIAYKDGRIDRLVGNDLTPPSLDPLTGVESKDVVISPETAVSARIYKPKPAAAQAQKLPLLIYIHGGGFCIESAFSPTYHCHLNSLVAKGNIVAVSIDYRRAPEHPLPIAYEDSWAAVKWVAAHSAGTGPDEWLNGIPDLDRVYFAGDSAGANIANHMAVRMGVEGLAGLNLRGLILVHPYFWGGKLIGDEEKLNPKEREFIEKLWYLACPTISGLDDPIVNPEFDPKLGRLAAERVAVYVAEKDGLKDRGWFYSDCLKKSGWRGSVEVVETKDQGHVFHLFNPTSDVAVDFVEKLAAFINGGSGE
>Tan0012108.1
MSVIASPPPPIPKSHLHPLFQQMDSTDPAGEEVVFQFLPIFRVFKSGRVERLIPADRVPPSTDPPTGVQSKDILIDPNTQLSVRIYLPNISDSTKKLPLLIYIHGGAFSVGSVASPIYHTHLLSLAAEANAVAVSVEYRLAPEHPLPAAYEDAWTAVEWAASHSNRDGAETWLNEHADFDRVFVVGDSAGANISYNVVGRASENDNGPKGLKIIGLGLVHPFFMIDKPDKLIEYIFPTSAGLEDPRMNPLSNPGLGSLRCNRVLIVAAEHDWLKDRARGFHAALRESGWKGSVEMVENEGEDHVFHLFNPTCENAVALVKRLASFIQSA
>Tan0022869.1
MDSEDEVVYELPRDFRILKSGRVERLILTDRVPPSTDQLTGVQSKDVLIDPQTGVSVRIYLPQLSDSTIKLPLLIYIHGGAFAIGSPAASMFHRHLVTLSAEANAVALSVEYRLAPENPLPAAYDDAWTAVEWAASHANRDGAETWLNEHADFDRVSVVGDSAGANICYNVVGRASESDNGPKGMKIIGLGLVHPYFLIDKLDKLIEFVFPTSAGLEDPRLNPKANPRLGRFRCERVLVLAAENDFLRDRARGVYVAFRESGFEGSLEMAETEGEDHGFHLFNPDTEKAAAVVKQLAFFIQSA
>Tan0005825.1
MAATSSPVEVDECRGVLRVYSDGSIVRSSNPSFNAPVLDDGSVLWKDLLFDPINDLHLRLYKPAISSSRLPVFFYIHGGGFCIGSRTWPNCQNYCFRLALELPALVISPDYRLAPENRLPAAIDDGFAAVRWLQAQARSDHPDPWLADVADYSRVFISGDSAGGNIAHHLAVGLGLGSPELAPVRVRGYVLLAPFFGGMVRTRSEAEGPKDAFLNLELIDRFWRLSIPIGSSTDHPVVNVFGPWSRDLEAVEVDPIMVVVGGGDLLKDRAAEYAEKLKKQGKKIELVEFEGKQHGFFTIDPNSEASNELMIVIKQFIAQHSH
MLYTYIFFQPYNFPFPFFKLFSVFFIPSSSLKKSDMAAADSNNPELELELELELFPYLRLYKNGVVQRLVGTRVTPPGLDPLTGVDSKDIIIVPETGVSARLYRPPAVHPRRKLPLVVYFHGGAFLITSSAEPIYHNNCLIPLAAATESVVVSVNYRLAPEHPLPAAYDDSWAALEWIAEQSQFSGDDAGQEPWLKQLVDFEKVFLVGDSAGANISHHMALRAKNSDVAGKIKIVGIGLIQPYFWGEEPIGSEIREPEKKALVDGWWNFVCPSDKGNDDLLINPFADGSPAIEGLAGEKVVVIVAEKDILRERGKLYYENLAKSDWKGKVEFFETEGEDHAFQLLDPNSEKAKSLLKRLASFVNNED
>Tan0007791.1
MAAVDSNIPELDLELLPYLRLYKNGVVERLAGTRVTPPGLDPLSGVHSKDIIIVPETGVSARLYRPTTAFDPRRKLPLVVYFHGGAFLIASSADPVYHNNCLIPLVAQAQTVVVSVNYRLAPEHPLPAAYDDSWAALQWIAAQSQSSDDQPAHEPWLKQHVDFEKVFLVGDSAGANISHHMGLRAQNSDLAGKIKIIGIALIHPYFWGQEPIGSEITEPEKKALVDRWWNFVCPSDRGNDDLLINPFADGSPAIEGLAGEKVVVIVAEKDILKNRGKLYYENLAKSEWKGNVEIFETEGEDHVFHIFDPTSEKAKILIKRLALFVNED
>Tan0018850.1
MALIGEAPGYLEVYSDGSVRRSIPEVIASSETQSSKNYKFKDVITDPKKPVTGRLFLPDITNAATKLPVLVYFHGGGFCIGSTTWIGYHHFLGDLAAASQSVILSVDYRLAPENRLPAAYEDCYSSLEWLSHQSSSEPWLQNADLSRVFLSGDSAGGNIVHHVAVKTIKCNISNLTIKGLLLIHPYFGSEKRTEKEKAQGAEGFVEMNDMFWRLSIPEGQDREYFGCNYENVPITNEEWSEFPSVVVFVAGLDFLKERGELYAKFLQQMKVKEVKLVEAAEESHIFHVFHPESEATRLLQKQMSQFMKSY
>Tan0019739.1
MDSSEPEIVIELLPLLRVYKNGRIERFIGTDFVPPSTDPLTGVTSKDVTILPESGVSARLFLPNLTHPTQRLPLVVYFHGGCFCTQSPFTAKFHNYLNALTAEARVVAVSVNYSKAPEHPIPAAYEDSWAALQWAISHRDREGPEIWLNKHVDFRRVFLAGVSAGANIAHNLAMVAGDPDCGVNIELTGVALEHPYFWGSVRIGKEAGDPVRAELFDRLWEFICPARPENDDPWVNPVAEGAARLARMRSGRVLVCVAEKDVLRDRGRLYYEALGDSGWMGVAEIVETEDEDHMFHLNDLEGQKAKDLIRRLGAFFNRDMPPSLLL
>Tan0002446.1
MTIGKNLILDVSGWLRLFDDGSVDRTWTGPPEVKFVAESVPPHDEFIDGVAVRDVVIDRKSGLRVRIYLPELKCGDGKKLPIVVHFHGGGFCISEADWFMYYHTYTGLVKSAEAICVSVYLRRAPEHRLPAALDDALSALRWLQSVALGDEIEPWITVNADFNRVFLIGDSSGGNLVHSVAALAGDADLAPLKLAGGIPIHPGFVRAKRSKSEMENPQSPFLTLDMVDKFLSLALPTGSSKDHPITCPMGTDAPPLESLNLPPFLLCIAEKDLIIDTEMEYYEAMKAANKEVEILMSKGMGHSFYLNKIALKIDPETAAESDHLFTGIARFIQQH
>Tan0014528.1
MKFKRMAAMYMDPRHKLQMPKLHLQNGVTSEEIEGLIRVYADGHVERPPIIPNVSCSPTASDKGVTAKDVLIDNFTNTWARIYIPNSQRNLPLLVYFHGGGFCVGSAAWSCYHEFLLNLASKTKCVILSINYRLSPENRLPAAYEDGFNALMWLKQQALTDPIEHKWWLGNCKPSKLFLAGDSAGANIAYNIATRLGLNESPILKPLTLKGIILIQPFFGGESRTKSEKLAAQFSSASALTLPTADTYWRLSLPPAANRDHPWSNPLVNGGAKLRETKLPPLMVCISELDILLDRNLEFCAAMAAAGKKVERVILKGVGHCFQILNKDQISTLRTQEMMGSIQAFILHQ
>Tan0004627.1
MRRKRMPTINLDQIPSFEEHVNGFKQHDVLVEEIEGLIRVYGNGYVERAQIVPCVSNALQPELGVTSWDVVVDKLNNIWARFYIPQQCQEKLPLLVYFHGGGFCVGSAAWSCYHEFLAKLSAKADCIIMSVNYRLAPENPLPAPYEDGLKILSWLKQVALVGAKQNWWSRYCDFTRIFLGGDSAGGNIAFNVAARVGGKTTASGAVVLKPLVIKGNILIQPFFGGESRTKSEKFLVQPPRSALTMAVSDTYWRLALPSGANRDHPWCNPSANGLFKVEDLRALPSLVCISEMDILKDRNLDFCSALHRAGKLVNYVVYEGVGHAFQVLNKSQLSQTRTLEMIDHIKDFLSV
>Tan0000342.1
MASNEIALNAAPWFVIYKDGRIDRLIGNDIDPPGLDPKTGVDSKDVVISPEDSVTVRIYRPKSTAAAGKQAQKLPLLVYFHGGGFCIETAFSPFYHQHINPWVAEANIVAVSVDYRRAPEHQLPIPFEDSWTALKWIAAHSNGTGPDEWLNEIADLNQVYLAGDSAGGNIAHRMALRAGTEGLAGVKIRGLQLIHPHFWGEKLIGEEKEWDPKDIFVVENLWYLVSKDIKGLDDPIVNPEHDPDLGRLAAERVAVYVAEKDNLKVRGRHYAECLRKSGWGGEIEVVETDGEGHVFHLFNPTCDSAADLVGQLAAFISGGRRG
>Tan0002801.1
MASNEIAHNFTPMLIAYKDGRIDRLVGNDLTPPSLDPLTGVESKDVVISPETAVSARIYKPKPAAAQAQKLPLLIYIHGGGFCIESAFSPTYHCHLNSLVAKGNIVAVSIDYRRAPEHPLPIAYEDSWAAVKWVAAHSAGTGPDEWLNGIPDLDRVYFAGDSAGANIANHMAVRMGVEGLAGLNLRGLILVHPYFWGGKLIGDEEKLNPKEREFIEKLWYLACPTISGLDDPIVNPEFDPKLGRLAAERVAVYVAEKDGLKDRGWFYSDCLKKSGWRGSVEVVETKDQGHVFHLFNPTSDVAVDFVEKLAAFINGGSGE
>Tan0012108.1
MSVIASPPPPIPKSHLHPLFQQMDSTDPAGEEVVFQFLPIFRVFKSGRVERLIPADRVPPSTDPPTGVQSKDILIDPNTQLSVRIYLPNISDSTKKLPLLIYIHGGAFSVGSVASPIYHTHLLSLAAEANAVAVSVEYRLAPEHPLPAAYEDAWTAVEWAASHSNRDGAETWLNEHADFDRVFVVGDSAGANISYNVVGRASENDNGPKGLKIIGLGLVHPFFMIDKPDKLIEYIFPTSAGLEDPRMNPLSNPGLGSLRCNRVLIVAAEHDWLKDRARGFHAALRESGWKGSVEMVENEGEDHVFHLFNPTCENAVALVKRLASFIQSA
>Tan0022869.1
MDSEDEVVYELPRDFRILKSGRVERLILTDRVPPSTDQLTGVQSKDVLIDPQTGVSVRIYLPQLSDSTIKLPLLIYIHGGAFAIGSPAASMFHRHLVTLSAEANAVALSVEYRLAPENPLPAAYDDAWTAVEWAASHANRDGAETWLNEHADFDRVSVVGDSAGANICYNVVGRASESDNGPKGMKIIGLGLVHPYFLIDKLDKLIEFVFPTSAGLEDPRLNPKANPRLGRFRCERVLVLAAENDFLRDRARGVYVAFRESGFEGSLEMAETEGEDHGFHLFNPDTEKAAAVVKQLAFFIQSA
>Tan0005825.1
MAATSSPVEVDECRGVLRVYSDGSIVRSSNPSFNAPVLDDGSVLWKDLLFDPINDLHLRLYKPAISSSRLPVFFYIHGGGFCIGSRTWPNCQNYCFRLALELPALVISPDYRLAPENRLPAAIDDGFAAVRWLQAQARSDHPDPWLADVADYSRVFISGDSAGGNIAHHLAVGLGLGSPELAPVRVRGYVLLAPFFGGMVRTRSEAEGPKDAFLNLELIDRFWRLSIPIGSSTDHPVVNVFGPWSRDLEAVEVDPIMVVVGGGDLLKDRAAEYAEKLKKQGKKIELVEFEGKQHGFFTIDPNSEASNELMIVIKQFIAQHSH
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University