Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Trichosanthes anguina
Species name
Trichosanthes anguina is a species of eudicot in the family Cucurbitaceae (cucumber family).
Species info
Gene sequence info
Trichosanthes_anguina.CHS.fa
Download
>Tan0003975.1
MATVEEILKGQRAEGPATVMAIGTAVPPNCIEQSTYPDFYFRITNNEHKIELKHKFKRMCEKSRIKKRYMVLTEELLKQNPEICAYEAPSLNSRQDIAILEVPKLGKQAAVNAITEWGRPTADITHLIFCTSSGVDMPGADYRLTKLLGLRPSVKRFMLYQQGCFAGATVLRLLKDLAENNRSARVLAVCSEITAVTFRGPSDFHLDSLVGQALFGDGAAAIIVGSDPIPGLERPIFEIISATQSILPNSDGAIDGHLREVGLTFHLLKDVPGLVSNNIQRLLLEAFGPLGHSDWNSIFWAVHPGGPAILDGIEMELGLGPEKLRASRHVLREYGNMSSACVLFVLDEMRKKSTENGLKTTGDGLEWGVLFGFGPGLTVETVVLRSVPI
>Tan0004897.1
MASVNEIVKAQRAEGPATVLGIGTATPPHSVLQSDYPDYYFRITNSEHMTNLKEKFTRMCEKSMIRKRHMCVTEEILRENPNMCAYMAPSLDARQDIVVVEVPKLGKEAAAKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLLKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSETHLDSMVGQALFGDGAAAVVIGSDPDLSVERPLYEVVWTGATILPESEGAIDGHLREVGLTFHLLKDVPGLISKNVEKSLKEAFTPLGITDWNSIFWIAHPGGPAILDQVEKKLGLKEEKMRATREVLREYGNMSSACVLFILDQMRKNSMEEGNSTTGEGLEWGVLFGFGPGLTVETVVLHSVDINETTVKANGTAAYY
>Tan0022541.1
MSNISCEGSAKLDHARARRIPTPGKATILAIGKAFPCQLVPQECLVEGYIRDTKCEDTTIKEKLERLCKTTTVRTRYTVMCKEILDKYPELVTEGSPTIRQRLEIANPAVVEMATEASKACIKEWGRSVEDITHIVYVSSSEIRLPGGDLYIANRLGLKNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRILLTTSETTILGFRPPNNARPYDLVGAALFGDGAAAVIIGTDPVPGQESPFMELNYAMQQFLPDTHNVIDGRLSEEGINFKLGRDLPQRIDDNIEEFCRKLTGKGKLVDFNDLFWAVHPGGPAILNKLESTLRLKIEKLECSRKALMDYGNVSSNTIFYVIENMRENLKREDGEEWGLALAFGPGITFEGILIRSL
>Tan0017333.1
MAEKKETNQSDEMRATILGIGTVVPTNCIHQSQYPDFYFRVTNSHHMTQLKQKFDTICKKSSIHKRYFHLNEEILKANPNICKYGAPSLDARQEMMAKEVPKLGKEAALKAIEEWGQPISNITHLIVSTSSCNSMPGVDTQLSNLLGLKPSVERFMLFQIGCHAAGSALRLAKNVVENTNNNVGARVLVVCIDITTMYFHAPSETHLDILVGQAIFSDGAAAVILGLGATANANPNVEVERGLFQIVSASQTLLPNSENGVIGNFREMGLSYHLSRNVPKYIGQNIKKILVDLCGSIESIIMDDIDFNSLFYVIHPGGRAILDEIEANLGLGEGKLEASRHVLHEYGNMAGPSVVFVLDEMRNKSIREGKSNTGEGLKWGLLIAFGPGITMEILVLQSLPLCSSLIHSQ
>Tan0018678.1
MASVYEIRKAQRADGPATILAIGTATPPHFILQSDYPDYYFRITNSQHMTNLKEKFTRMCEKSMIRKRHMYLTEEILRENPNMCAYMAPSLDARQDIVVVEVPKLGKEAAAKAIKEWGQPKSKITHLVFCTTSGVDMPGSDYQLLKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSETHLDSMVGQALFGDGAGAVIIGSDPDLSVERPLYELVWTGATILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFTPLGITDWNSIFWIAHPGGPAILDQVEAKLGLREEKMRTTREVLSEYGNMSSACVLFILDQMRKNSMEEGNSTTGEGLEWGVLFGFGPGLTVETVVLHSVDIKETTVKAH
>Tan0003678.1
MECKMLEREEGNESCEYNNNNKRATLLGIGTAVPPNFLYQTQYPDFYFRVTNSQHMTHSIRKFNRIWPDCQLSKLLSVGRFVLYQHGCNAAGTALGLAKDVAENNVNNNINARVLVVAVDMMSMYFHAPSEKRKKSMREGKSSTGEGLEWGALVALGPGLTLETLILHSVSML
MATVEEILKGQRAEGPATVMAIGTAVPPNCIEQSTYPDFYFRITNNEHKIELKHKFKRMCEKSRIKKRYMVLTEELLKQNPEICAYEAPSLNSRQDIAILEVPKLGKQAAVNAITEWGRPTADITHLIFCTSSGVDMPGADYRLTKLLGLRPSVKRFMLYQQGCFAGATVLRLLKDLAENNRSARVLAVCSEITAVTFRGPSDFHLDSLVGQALFGDGAAAIIVGSDPIPGLERPIFEIISATQSILPNSDGAIDGHLREVGLTFHLLKDVPGLVSNNIQRLLLEAFGPLGHSDWNSIFWAVHPGGPAILDGIEMELGLGPEKLRASRHVLREYGNMSSACVLFVLDEMRKKSTENGLKTTGDGLEWGVLFGFGPGLTVETVVLRSVPI
>Tan0004897.1
MASVNEIVKAQRAEGPATVLGIGTATPPHSVLQSDYPDYYFRITNSEHMTNLKEKFTRMCEKSMIRKRHMCVTEEILRENPNMCAYMAPSLDARQDIVVVEVPKLGKEAAAKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLLKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSETHLDSMVGQALFGDGAAAVVIGSDPDLSVERPLYEVVWTGATILPESEGAIDGHLREVGLTFHLLKDVPGLISKNVEKSLKEAFTPLGITDWNSIFWIAHPGGPAILDQVEKKLGLKEEKMRATREVLREYGNMSSACVLFILDQMRKNSMEEGNSTTGEGLEWGVLFGFGPGLTVETVVLHSVDINETTVKANGTAAYY
>Tan0022541.1
MSNISCEGSAKLDHARARRIPTPGKATILAIGKAFPCQLVPQECLVEGYIRDTKCEDTTIKEKLERLCKTTTVRTRYTVMCKEILDKYPELVTEGSPTIRQRLEIANPAVVEMATEASKACIKEWGRSVEDITHIVYVSSSEIRLPGGDLYIANRLGLKNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRILLTTSETTILGFRPPNNARPYDLVGAALFGDGAAAVIIGTDPVPGQESPFMELNYAMQQFLPDTHNVIDGRLSEEGINFKLGRDLPQRIDDNIEEFCRKLTGKGKLVDFNDLFWAVHPGGPAILNKLESTLRLKIEKLECSRKALMDYGNVSSNTIFYVIENMRENLKREDGEEWGLALAFGPGITFEGILIRSL
>Tan0017333.1
MAEKKETNQSDEMRATILGIGTVVPTNCIHQSQYPDFYFRVTNSHHMTQLKQKFDTICKKSSIHKRYFHLNEEILKANPNICKYGAPSLDARQEMMAKEVPKLGKEAALKAIEEWGQPISNITHLIVSTSSCNSMPGVDTQLSNLLGLKPSVERFMLFQIGCHAAGSALRLAKNVVENTNNNVGARVLVVCIDITTMYFHAPSETHLDILVGQAIFSDGAAAVILGLGATANANPNVEVERGLFQIVSASQTLLPNSENGVIGNFREMGLSYHLSRNVPKYIGQNIKKILVDLCGSIESIIMDDIDFNSLFYVIHPGGRAILDEIEANLGLGEGKLEASRHVLHEYGNMAGPSVVFVLDEMRNKSIREGKSNTGEGLKWGLLIAFGPGITMEILVLQSLPLCSSLIHSQ
>Tan0018678.1
MASVYEIRKAQRADGPATILAIGTATPPHFILQSDYPDYYFRITNSQHMTNLKEKFTRMCEKSMIRKRHMYLTEEILRENPNMCAYMAPSLDARQDIVVVEVPKLGKEAAAKAIKEWGQPKSKITHLVFCTTSGVDMPGSDYQLLKLLGLRPSVKRYMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSETHLDSMVGQALFGDGAGAVIIGSDPDLSVERPLYELVWTGATILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFTPLGITDWNSIFWIAHPGGPAILDQVEAKLGLREEKMRTTREVLSEYGNMSSACVLFILDQMRKNSMEEGNSTTGEGLEWGVLFGFGPGLTVETVVLHSVDIKETTVKAH
>Tan0003678.1
MECKMLEREEGNESCEYNNNNKRATLLGIGTAVPPNFLYQTQYPDFYFRVTNSQHMTHSIRKFNRIWPDCQLSKLLSVGRFVLYQHGCNAAGTALGLAKDVAENNVNNNINARVLVVAVDMMSMYFHAPSEKRKKSMREGKSSTGEGLEWGALVALGPGLTLETLILHSVSML
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University