Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Trema orientalis
Species name
Trema orientale is a species of eudicot in the family Cannabaceae (hemp family).
Species info
Gene sequence info
Trema_orientalis.CHS.fa
Download
>rna-gnl|WGS:JXTC|TorRG33x02_089860.1
MGTVDKIQAGNPRAQGVASILAIGTANPFNTVIQADYPDYYFKVTNSEDKTKLKDKFKQICEKSMIKKRYMDLTEDILKANPNMCLYSAPSLDVRHHLKIKEIIP
>rna-gnl|WGS:JXTC|TorRG33x02_140380.1
MIKKRYMHLTEEVLKENPNLCAYAAPSLDVRQDLKVSEVPKLGEKAAVKAIKEWGQPLSNITHIVFNATSGVDMPGADYHLAKSLGLKPSVRRVMLYHQGCFAGGTVLRIAKDLAENNPGARVLVVCSEITVTTFRGPAEGDNACLVGQAIFGDGAASIIIGADDSLLPSERALFRLMSSLETVLPDCEEAIQGHLREVGLTFQLIPEVPALIRDNIEKCLDDAFTPFGIDDWNSLFWVPHPGGAAILREIEGRLNLDKDRLRATWHVLKEYGNMSSATVFFILDEMRKKSIQEGKSTTGEGLKWGVLFGFGPGITVETVVLQSVPISVE
>rna-gnl|WGS:JXTC|TorRG33x02_140390.1
MATVEKIQPVNPRGKGVASILAIGTTNPNNVVYQADYPDYYFNITNSEDKPKLKEKFKRICKKNITFKL
>rna-gnl|WGS:JXTC|TorRG33x02_185790.1
MSKVEGSGAPKQYPERTRRIPTPGKATILAMGKAFPSQLIPQECLVEGYIRDTKCQDISVKEKLERLCKTTTVKTRYTVMSKDILEKYPELATEGIPTIKQRLDIANPAVVEMAKEASLACVEEWGRPAQDITHIVYVSSSEIRLPGGDLYLASQLGLRNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGTDPVMGRESPFMEINYAIQQFLPDTQNVIDGKLSEEGINFKLGRDLPQKIEENIEEFCKKIMAKAELKEYNDLFWAVHPGGPAILNKLESTLKLSSDKLECSRRALMDYGNVSSNTIFYVMENMREHLKREGGEEWGLGLAFGPGITFEGVLIRSL
>rna-gnl|WGS:JXTC|TorRG33x02_195850.1
MPGAEFQLIKSLGLKPTVKRVMLYHQGCFAGGTVLRIAKDLAENNAGARVLVVCSEITVSTFRGPSEDDMACLVGQAIFGDGAAAVVIGADDHKLLPDETPLFRLVSASQTIIPSSEGAIEGRVREVGLTFHLSHKVPKVIGENIEKYLEDVFGPFGISDWNSLFWAPHPGGAAILREIEGRVGLGKEKLRATWHVLSEYGNMSSACVFFILDEMRKKSFEEGKGSSGEFCLGLDLGSRWRPLFCRVSLIVEEN
>rna-gnl|WGS:JXTC|TorRG33x02_208210.1
MGSQDNAQVIFPKKANPGKATILALGKAFPHQLVMQEYLVDGYFRDTNCDDPDLKRKLTRLCKTTTVKTRYVVMSEEILRKYPELALEGKPTVKQRLDICNDAVTEMAIEASRSCIKNWGRPVSDITHLVYVSSSEVRLPGGDLFLATGLGLSPETQRVMLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGYKPPSADRPYDLVGVALFGDGAGAMIIGSDPDSDTEKGLFELHVAAQEFLPGTDKTIDGRLSEEGISFKLDRELPQVIEDNVEGFCKKLMGVIGFGKEYYNKLFWAVHPGGPAILNRIEKRLDLVPEKLIASRRALMDYGNASSNTIVYVLEYMIEESSKMKKADHVKEESEWGLILAFGPGVTFEGILARNLTTVRE
>rna-gnl|WGS:JXTC|TorRG33x02_250770.1
MVTVSEVRNAQRAEGPATIMAIGTATPPNCVEQSSYPDYYFRITNSEHKTELKEKFKRMFCSKGEKSMIKKRYMYLTEEILKENPSVCAYEAPSLDARQDMVVVEVPKLGKEAATRAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDSHLDSLVGQALFGDGSAAIIIGADPIPGVEKPLFELVSTAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVEIKLGLKPEKLRSTRHVLSEFGNMSSACVLFILDEMRKSCAKNGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVAI
>rna-gnl|WGS:JXTC|TorRG33x02_314210.1
MASVTVDEIRKAQRAEGPATVLAIGTATPHNCVSQADYPDYYFRITNSEHMTELKEKFKRMCEKSMIKKRYMHLTEEILKENPKMCEYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGLPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSMVGQALFGDGAAAVIVGADPDPSAGERPLFEMVSAAQTILPDSEGAIDGHLREAGLTFHLLKDVPGLISKNIEKSLTEAFSPLGISDWNSLFWIAHPGGPAILDQVEAKLKLKEEKLRATRHVLSEYGNMSSACVLFILDEMRKKSAEDGKPTTGEGLDWGVLFGFGPGLTVETVVLHSVAATATN
>rna-gnl|WGS:JXTC|TorRG33x02_326810.1
MIKKRYMDLTEDILKANPNMCVYSAPSLDVRHHLKIKEIPKLGERAAVKAIQEWGQPVSKITHVIFSSTSGVHMPGADFQITKSLGLNPSVKRVMLYHQGCYAGGTVLRIAKDLAENNPGARVLVVCSETTHTTFRGPSEDDMACLVEQALFGDGAAAVIIGADNGLLSSEAPLFRVVSTLETIIPDSEEAIQGHLREIGLTLQLTPKLPNLVGGNIEKCLEDAFSPLGVSDWNSLFWAPHPGGAAILREIEGGAKLEKEKLRAAWHVLEEYGNMSSATVFFILDEMRKKSTQERKSTTGEGLKWGVLFGFGPGVTVETVVLQSVPIKTE
MGTVDKIQAGNPRAQGVASILAIGTANPFNTVIQADYPDYYFKVTNSEDKTKLKDKFKQICEKSMIKKRYMDLTEDILKANPNMCLYSAPSLDVRHHLKIKEIIP
>rna-gnl|WGS:JXTC|TorRG33x02_140380.1
MIKKRYMHLTEEVLKENPNLCAYAAPSLDVRQDLKVSEVPKLGEKAAVKAIKEWGQPLSNITHIVFNATSGVDMPGADYHLAKSLGLKPSVRRVMLYHQGCFAGGTVLRIAKDLAENNPGARVLVVCSEITVTTFRGPAEGDNACLVGQAIFGDGAASIIIGADDSLLPSERALFRLMSSLETVLPDCEEAIQGHLREVGLTFQLIPEVPALIRDNIEKCLDDAFTPFGIDDWNSLFWVPHPGGAAILREIEGRLNLDKDRLRATWHVLKEYGNMSSATVFFILDEMRKKSIQEGKSTTGEGLKWGVLFGFGPGITVETVVLQSVPISVE
>rna-gnl|WGS:JXTC|TorRG33x02_140390.1
MATVEKIQPVNPRGKGVASILAIGTTNPNNVVYQADYPDYYFNITNSEDKPKLKEKFKRICKKNITFKL
>rna-gnl|WGS:JXTC|TorRG33x02_185790.1
MSKVEGSGAPKQYPERTRRIPTPGKATILAMGKAFPSQLIPQECLVEGYIRDTKCQDISVKEKLERLCKTTTVKTRYTVMSKDILEKYPELATEGIPTIKQRLDIANPAVVEMAKEASLACVEEWGRPAQDITHIVYVSSSEIRLPGGDLYLASQLGLRNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGTDPVMGRESPFMEINYAIQQFLPDTQNVIDGKLSEEGINFKLGRDLPQKIEENIEEFCKKIMAKAELKEYNDLFWAVHPGGPAILNKLESTLKLSSDKLECSRRALMDYGNVSSNTIFYVMENMREHLKREGGEEWGLGLAFGPGITFEGVLIRSL
>rna-gnl|WGS:JXTC|TorRG33x02_195850.1
MPGAEFQLIKSLGLKPTVKRVMLYHQGCFAGGTVLRIAKDLAENNAGARVLVVCSEITVSTFRGPSEDDMACLVGQAIFGDGAAAVVIGADDHKLLPDETPLFRLVSASQTIIPSSEGAIEGRVREVGLTFHLSHKVPKVIGENIEKYLEDVFGPFGISDWNSLFWAPHPGGAAILREIEGRVGLGKEKLRATWHVLSEYGNMSSACVFFILDEMRKKSFEEGKGSSGEFCLGLDLGSRWRPLFCRVSLIVEEN
>rna-gnl|WGS:JXTC|TorRG33x02_208210.1
MGSQDNAQVIFPKKANPGKATILALGKAFPHQLVMQEYLVDGYFRDTNCDDPDLKRKLTRLCKTTTVKTRYVVMSEEILRKYPELALEGKPTVKQRLDICNDAVTEMAIEASRSCIKNWGRPVSDITHLVYVSSSEVRLPGGDLFLATGLGLSPETQRVMLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGYKPPSADRPYDLVGVALFGDGAGAMIIGSDPDSDTEKGLFELHVAAQEFLPGTDKTIDGRLSEEGISFKLDRELPQVIEDNVEGFCKKLMGVIGFGKEYYNKLFWAVHPGGPAILNRIEKRLDLVPEKLIASRRALMDYGNASSNTIVYVLEYMIEESSKMKKADHVKEESEWGLILAFGPGVTFEGILARNLTTVRE
>rna-gnl|WGS:JXTC|TorRG33x02_250770.1
MVTVSEVRNAQRAEGPATIMAIGTATPPNCVEQSSYPDYYFRITNSEHKTELKEKFKRMFCSKGEKSMIKKRYMYLTEEILKENPSVCAYEAPSLDARQDMVVVEVPKLGKEAATRAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDSHLDSLVGQALFGDGSAAIIIGADPIPGVEKPLFELVSTAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVEIKLGLKPEKLRSTRHVLSEFGNMSSACVLFILDEMRKSCAKNGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVAI
>rna-gnl|WGS:JXTC|TorRG33x02_314210.1
MASVTVDEIRKAQRAEGPATVLAIGTATPHNCVSQADYPDYYFRITNSEHMTELKEKFKRMCEKSMIKKRYMHLTEEILKENPKMCEYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGLPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSMVGQALFGDGAAAVIVGADPDPSAGERPLFEMVSAAQTILPDSEGAIDGHLREAGLTFHLLKDVPGLISKNIEKSLTEAFSPLGISDWNSLFWIAHPGGPAILDQVEAKLKLKEEKLRATRHVLSEYGNMSSACVLFILDEMRKKSAEDGKPTTGEGLDWGVLFGFGPGLTVETVVLHSVAATATN
>rna-gnl|WGS:JXTC|TorRG33x02_326810.1
MIKKRYMDLTEDILKANPNMCVYSAPSLDVRHHLKIKEIPKLGERAAVKAIQEWGQPVSKITHVIFSSTSGVHMPGADFQITKSLGLNPSVKRVMLYHQGCYAGGTVLRIAKDLAENNPGARVLVVCSETTHTTFRGPSEDDMACLVEQALFGDGAAAVIIGADNGLLSSEAPLFRVVSTLETIIPDSEEAIQGHLREIGLTLQLTPKLPNLVGGNIEKCLEDAFSPLGVSDWNSLFWAPHPGGAAILREIEGGAKLEKEKLRAAWHVLEEYGNMSSATVFFILDEMRKKSTQERKSTTGEGLKWGVLFGFGPGVTVETVVLQSVPIKTE
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University