Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Toona sinensis
Species name
Toona sinensis is a species of eudicot in the family Meliaceae (mahogany family).
Species info
Gene sequence info
Toona_sinensis.OMT.fa
Download
>Maker00018192
MDRIEDQGHGARELFQAQAHLYKHVFSYMSSMLLKCAVELGIPDIISQHGRPITLPDPELVSALGIQPTKTNGLLRLMRFLAHAGFFSATKVQNAQEEEGYALTSSSMLLLKDKSYCLSPFVLALVHPAFVTPCHFLSNWFRGDELAAFETAHGMNFWDYVEQNPEFNNVFNQGMASDSQMANLIVKDCKPIFERLGSMVDVGGGTGSFARIISEAFPDIKCTVLDLPHVVANLPETENLKFIAGFFSWTKVVVNDQEEEEAYVLTSSSMLLLKDKSNCLSPFVLSMLDPAILTPCQFFGTVSVKQWPVILKWQTWVLECKPIFDGLGSSVDVGGCTGSFARISGISSHQMHGFFATRKIDDEDQDQEGYFLTPFSKFLDKDNVISLSPVVLVMLDPVLVNPWHSLDDWFLGNEFTPFETVHGISYWDYGNKIWSLWKNKNELMARDPQITSSVIKDH
>Maker00018156
MDPMHDQGAREMFEAQAHLYKLMYNRVSSMSVKCAVELGIPDVIHSHGRPITLPELVSALGIQPTRTASLCRLMRLLVHSGGINLQHWNCSWMNLWDYVVQNPEFNSSFNQGMASDSQMENLVL
>Maker00021846
MDRACFNELVLTMGRNLIAHIKVQDHPRICATFFNDFKSLLIWDGMEKVSALAIQPTKTTSLCRLMRLLVHSDLFSTTKVQSDRGEEEEEAYPLTPLSMLLLKDKSTVFHHMLWECFTLGNELTVFETAHGMNLWDYMMQNTEFNSSFNQAMASDSQMANLVVKDCKPIFEGLGSLVDLGGGTGSFSRIISEAFPGIKSKVLDLPHVVANLPETENLKFIAGKGEICRSMDHMKSANELFQGQSHLYKHLFNYISSMSLKCAVELGIPEIIHNHGKPITLPELVSAIPLHPTKTSSVYRLMRLLVHSGIFSATKVVVNDQEEEQAYVLTSSSMLLLKDKSNCLSPFVLSMLDPAILTPWQFLGNWFQGNETTPFESAHGLNFWDYGEQNSEFNSGFSQAMASDSQMANLVVKDCKSIFEGLGSLVDVGGCTGSFARKISQEFPHIKCTVFDLPHVVANLPDNENLNFVGGDMFQSIPPADAFLFKYSNMDLNLRHGSTDELFQAQSYIYKHMCHFIDSMALKCAIQLKIPDIIYTHKKPITISELASALQISPTKTSCLQRLMNILVHSGFFATSKIDDEDQEQEGYVLTPFSKFLVKDNVISLSPVVLAMLDPVLVNPWHSLDDWFRGNEFTPFETGHGISFWEYGKQNLEFMESLNELMARDSQITSLVIKDHKQIFEGLDSLVDVGGGTGTLARTISEAFPELKCTSDRGEEEEEAYALTPISMLLLKDKSYCLSPYVAGMLHSVLTNPFHFLSSWFRGNELTAFETAHGMNLCYMMQNPEFNSSFNQAMASDSQMANLVVKDCRPIFEGLGSLVDLGGGTGSFSRIISEAFPGIKSKVLDLPHVVANLPETENLKFIAGKGEICRSMDHMKSANELFQGQSLLYKTIRKYSNMDLNLRHGSTDELFQAQSYIYKHMCHFIDSMALKCAVQLKIPDIIYTHKKPITISDTPKTSCLQRLMNILVHSGFFATSKTDDEDQEQEGYVLTPFSKFLVKDNVISLLPVVLAMLDPVLVNPWHSLDDWFRGNEFTPFETGHGISFWEYGKQNLEFMESLNELMARDSQITSLVIKDHKQIFEGLDSLVDVGGGTGTLARTISEAFPELKCRGARELFGAQAHLYKLMYNYVSSMSVMCAAELGIPDIIHSHGRPITLPELVSALAIQPTKTTSLCRLMRLLVHSGLFSATKVQCDRGEEEEEAYALTPLSMMLLKGKSYCLSPYVVGMLHSVLTNPFHFLSSWFRGNELTAFETAHGMNLWDYMMQNPEFNSSFNQAMASDSQMANLVVKDCKPIFEGLGSLVDLGGGTGSFSRIISEAFPGIKSKVLDLPHVVANLPETENLKFIAGKGEICRSMDHMKSANELFQGQSHLYKSMDPMKDLGARELFAAQAHLYKLMYNYVSSMSMKCAAELGIPDIIHSHGRPITIPELVSALAIQPTKTTSLCRLMRLLVHSGLFSATKVQSDRGEEEEEAYALTPLSMLLLKDKSYCLSPYVVGLLHSVVINPFHFLSSWFRGNELTAFETACGMNLWDYMVQNPEFNSSFNQAMASDSQMANLVVKDCKPIFEGLGSLVDLGGGTGSFSRIISEAFPGIKSKVLDLPHVVANLPETENLKFIAGDMLQYLQHPHTTALGFENNDKRAWVERAEKKDIKAALSVLSSNISAATFLSSVSLTLSSLIGAWLGSASNNNMFESKLIFGDTRASTISVKYISLLSCFLLAFSCFVESTRYYVHSNYLISMPDSNIPIRYVEMAVIKGGDFWSLGLRALYFALNLLLWFFGPIPMFLSSIFMVIILYYLDTNKIPLHYYNSPESPSSKRVSERISGKVTFNDQHQRGCGCGCGCGLR
>Maker00021921
MVLPVLKLGALALKTLSKPLAAKLKQQAAIHPRFRQSIISMAQANQYRVTTRMQRRIHSHATDVEIRPLNEEKAVQAAVDLIGEVLIFTVAGAAVIFEVQRSARSEVRKEEIRKQDLEANQYRITTRMQRRIHSHATDVEIRPLNEEKAVQAAVDLIGEVFIFTVAGAAVIFEVQRSARSEVRKEEIRKQDLEGARELFGALAHLYKLMYNYVSSMSVKCAAELGIPDIIHSHGRPITLPELVSALAIQPTKTNSLCRLMRLLVHSGLFSATKVQCDRGEEEEEALSPLSILLLKVLLFVTICCGNASLCFNKSNPFSVMFHEYNRLGALALKTLSKPLAAKLKQQAAIHPRFRQSIISMAQLFVRALILQVPDHLLFLSKSVDLISNCLHFLQIIESQQECKDASNSHATDVEIRPLNEEKAVQAAVDLIGEVFIFTVAGAAVIFEVQRSARSEARKEEIRKQELEALRQRDEGLAREVELLRQKLEELEQLAKSRGLSGIFNFKDATTENGKLAKPA
>Maker00020762
MTLNQLLTALPIHPIKIQSVHHLMRILVHSGFFAIQKLGRDSQEEGYILTGASQLLLKDNPLSVTPFLLAVLDPVLTTPWHHVSTWFQNDDPSPFSTAHGTTHGLATIVVIHKCKHMDMFFTDGEYESELLKAQAHVWNHIFNFINSMSLKCAVQLGISEIIHIHKKPMTLDELVSALPIHATKTHCVYRLMRILVHSGFFAIQKLGQDSQEEGYILTKASQLLLKDNPLSVTPFLLAMLDPVLTTPWHHIVYIGRKMDMFFTDGVHESELLQAQAHVWNHIFNFINSMSLKCAIQLGIPDIVHNHKKPMTLNQLLTAIPIHPTKIQCVHRLMRILVHSGFFAKQKLGQDSQEEGYILTRASLLLLKDNPLSVTPFLLAMLDPVLTTPWHHVSTWLQNDDPSPFSTAHGTTLWDYAGHEPNLNNFFNEAMASDARLATSVLIHKCTHVFEGLNSLVDVGGGTGTMAKAIAKAFQQMECTVFDLPHVVADLKDDGNLKYAGGDLFEAIPPADAVLLKLLQAQAHVWNSSFNYINSMSLKCAVQLGIPDIIHKHGKPMPLSQMVSALNFTLASLFFEHLAKMSKMKSIFLHLLLDSSKGRIVYIGRKMDMFFTDGVHESELLQAQAHVWNHIFNFINSMSLKCAIQLGIPDIVRNHKKPMTLNQLLTALPIHPTKIQCVHRLMRILVHSGFFAKQKLGQDSQEEGYILTRASLLLLKDNPLSVTPFLLAMLDPVLTTPWHHVSTWLQNDDPSPFSTAHGTTFWDYAGHEPNLNNFFNEAMASDARLATSVLIHKCTHVFEGLNSLVDVGGGTGTMAKAIAKAFQQMECTVFDLPHVVADLKDDGNLKYAGGDLFEAIPPADAVLLKKKLFIIIIIIILKF
>Maker00013289
MTKKKAIFLLILLRDNPLSDVFRWLNTLVDVGGGTETLAKAIAKPFPHLECTIFYLPLVVAYLKGEENLKYVGGDMFEAGGSSSELLHAQAQVWNSAFNYINSMSLKCAVQLGIPDVIHKHGKPMPLSQMVSALNVHPSKAQCIQRLMRILVHSGFFAQPTFGKNEQEEEYFLTPASRLLLKNDPLSAAPFVLLAFIYTGYHQQRLWPIHDTLSDNHGTQCPPKQRSLDSTPYGPFSSHSVFFAQHKLARRRVFPYPASRILLKDKPLKAAPVVLLVVDMAITTSFNFLSTWLQNDDPTLFQTANGKNIWVPYSELIARVVIEAVKRCSRVDVPGLLERWHRMTKANATAFPLRYHVVDTEEV
>Maker00003580
MEEMRREEIMEEEEAEVEIWKYVFGFVNMAVVKCAIELGIAEAIENHGSPMTITELSSTLNCTPSLLHRIMRFLVHHRFFKENPTSQGLVAYEQMPLSRRLIRRGENSMAAFILLESSQVMLAPWHSLSARVIANGMSAFNTAHGKDVWGFAAADAGHNKLINDAMACDARVAVPAIVKGCPEVFDGIETLVDVGGGDGTTLRILVKAFPWIKGINFDLPHVVNVAENFHGVKHVGGDMFDCVPRADATLIKVRNIFFYFFLRYLLQNIDSKAEIQIIKML
>Maker00033255
MRRESIMEEEDAEVEIWKYVFGFVNMAVAKCAIELGIAEAIENHGSPMTISELSSTLNCAPSLLHRIMRFLVHHRFFKEKPTSQGLIAYEQTPLSLRLMKHGENSMAAFILLESSQVMLAPWHSLSARVLANGTSAFNTAHGKDVWGFAAADAGHNKLFNEAMACDARVAVPAIIKGCLQVFDGVETLVDVGGGDGTTLRILVEAFPWIKGINFDLPHVVNVAENFHGVEHVGGDMFDCVPRADAILIKVGSFQMREFVLFKM
MDRIEDQGHGARELFQAQAHLYKHVFSYMSSMLLKCAVELGIPDIISQHGRPITLPDPELVSALGIQPTKTNGLLRLMRFLAHAGFFSATKVQNAQEEEGYALTSSSMLLLKDKSYCLSPFVLALVHPAFVTPCHFLSNWFRGDELAAFETAHGMNFWDYVEQNPEFNNVFNQGMASDSQMANLIVKDCKPIFERLGSMVDVGGGTGSFARIISEAFPDIKCTVLDLPHVVANLPETENLKFIAGFFSWTKVVVNDQEEEEAYVLTSSSMLLLKDKSNCLSPFVLSMLDPAILTPCQFFGTVSVKQWPVILKWQTWVLECKPIFDGLGSSVDVGGCTGSFARISGISSHQMHGFFATRKIDDEDQDQEGYFLTPFSKFLDKDNVISLSPVVLVMLDPVLVNPWHSLDDWFLGNEFTPFETVHGISYWDYGNKIWSLWKNKNELMARDPQITSSVIKDH
>Maker00018156
MDPMHDQGAREMFEAQAHLYKLMYNRVSSMSVKCAVELGIPDVIHSHGRPITLPELVSALGIQPTRTASLCRLMRLLVHSGGINLQHWNCSWMNLWDYVVQNPEFNSSFNQGMASDSQMENLVL
>Maker00021846
MDRACFNELVLTMGRNLIAHIKVQDHPRICATFFNDFKSLLIWDGMEKVSALAIQPTKTTSLCRLMRLLVHSDLFSTTKVQSDRGEEEEEAYPLTPLSMLLLKDKSTVFHHMLWECFTLGNELTVFETAHGMNLWDYMMQNTEFNSSFNQAMASDSQMANLVVKDCKPIFEGLGSLVDLGGGTGSFSRIISEAFPGIKSKVLDLPHVVANLPETENLKFIAGKGEICRSMDHMKSANELFQGQSHLYKHLFNYISSMSLKCAVELGIPEIIHNHGKPITLPELVSAIPLHPTKTSSVYRLMRLLVHSGIFSATKVVVNDQEEEQAYVLTSSSMLLLKDKSNCLSPFVLSMLDPAILTPWQFLGNWFQGNETTPFESAHGLNFWDYGEQNSEFNSGFSQAMASDSQMANLVVKDCKSIFEGLGSLVDVGGCTGSFARKISQEFPHIKCTVFDLPHVVANLPDNENLNFVGGDMFQSIPPADAFLFKYSNMDLNLRHGSTDELFQAQSYIYKHMCHFIDSMALKCAIQLKIPDIIYTHKKPITISELASALQISPTKTSCLQRLMNILVHSGFFATSKIDDEDQEQEGYVLTPFSKFLVKDNVISLSPVVLAMLDPVLVNPWHSLDDWFRGNEFTPFETGHGISFWEYGKQNLEFMESLNELMARDSQITSLVIKDHKQIFEGLDSLVDVGGGTGTLARTISEAFPELKCTSDRGEEEEEAYALTPISMLLLKDKSYCLSPYVAGMLHSVLTNPFHFLSSWFRGNELTAFETAHGMNLCYMMQNPEFNSSFNQAMASDSQMANLVVKDCRPIFEGLGSLVDLGGGTGSFSRIISEAFPGIKSKVLDLPHVVANLPETENLKFIAGKGEICRSMDHMKSANELFQGQSLLYKTIRKYSNMDLNLRHGSTDELFQAQSYIYKHMCHFIDSMALKCAVQLKIPDIIYTHKKPITISDTPKTSCLQRLMNILVHSGFFATSKTDDEDQEQEGYVLTPFSKFLVKDNVISLLPVVLAMLDPVLVNPWHSLDDWFRGNEFTPFETGHGISFWEYGKQNLEFMESLNELMARDSQITSLVIKDHKQIFEGLDSLVDVGGGTGTLARTISEAFPELKCRGARELFGAQAHLYKLMYNYVSSMSVMCAAELGIPDIIHSHGRPITLPELVSALAIQPTKTTSLCRLMRLLVHSGLFSATKVQCDRGEEEEEAYALTPLSMMLLKGKSYCLSPYVVGMLHSVLTNPFHFLSSWFRGNELTAFETAHGMNLWDYMMQNPEFNSSFNQAMASDSQMANLVVKDCKPIFEGLGSLVDLGGGTGSFSRIISEAFPGIKSKVLDLPHVVANLPETENLKFIAGKGEICRSMDHMKSANELFQGQSHLYKSMDPMKDLGARELFAAQAHLYKLMYNYVSSMSMKCAAELGIPDIIHSHGRPITIPELVSALAIQPTKTTSLCRLMRLLVHSGLFSATKVQSDRGEEEEEAYALTPLSMLLLKDKSYCLSPYVVGLLHSVVINPFHFLSSWFRGNELTAFETACGMNLWDYMVQNPEFNSSFNQAMASDSQMANLVVKDCKPIFEGLGSLVDLGGGTGSFSRIISEAFPGIKSKVLDLPHVVANLPETENLKFIAGDMLQYLQHPHTTALGFENNDKRAWVERAEKKDIKAALSVLSSNISAATFLSSVSLTLSSLIGAWLGSASNNNMFESKLIFGDTRASTISVKYISLLSCFLLAFSCFVESTRYYVHSNYLISMPDSNIPIRYVEMAVIKGGDFWSLGLRALYFALNLLLWFFGPIPMFLSSIFMVIILYYLDTNKIPLHYYNSPESPSSKRVSERISGKVTFNDQHQRGCGCGCGCGLR
>Maker00021921
MVLPVLKLGALALKTLSKPLAAKLKQQAAIHPRFRQSIISMAQANQYRVTTRMQRRIHSHATDVEIRPLNEEKAVQAAVDLIGEVLIFTVAGAAVIFEVQRSARSEVRKEEIRKQDLEANQYRITTRMQRRIHSHATDVEIRPLNEEKAVQAAVDLIGEVFIFTVAGAAVIFEVQRSARSEVRKEEIRKQDLEGARELFGALAHLYKLMYNYVSSMSVKCAAELGIPDIIHSHGRPITLPELVSALAIQPTKTNSLCRLMRLLVHSGLFSATKVQCDRGEEEEEALSPLSILLLKVLLFVTICCGNASLCFNKSNPFSVMFHEYNRLGALALKTLSKPLAAKLKQQAAIHPRFRQSIISMAQLFVRALILQVPDHLLFLSKSVDLISNCLHFLQIIESQQECKDASNSHATDVEIRPLNEEKAVQAAVDLIGEVFIFTVAGAAVIFEVQRSARSEARKEEIRKQELEALRQRDEGLAREVELLRQKLEELEQLAKSRGLSGIFNFKDATTENGKLAKPA
>Maker00020762
MTLNQLLTALPIHPIKIQSVHHLMRILVHSGFFAIQKLGRDSQEEGYILTGASQLLLKDNPLSVTPFLLAVLDPVLTTPWHHVSTWFQNDDPSPFSTAHGTTHGLATIVVIHKCKHMDMFFTDGEYESELLKAQAHVWNHIFNFINSMSLKCAVQLGISEIIHIHKKPMTLDELVSALPIHATKTHCVYRLMRILVHSGFFAIQKLGQDSQEEGYILTKASQLLLKDNPLSVTPFLLAMLDPVLTTPWHHIVYIGRKMDMFFTDGVHESELLQAQAHVWNHIFNFINSMSLKCAIQLGIPDIVHNHKKPMTLNQLLTAIPIHPTKIQCVHRLMRILVHSGFFAKQKLGQDSQEEGYILTRASLLLLKDNPLSVTPFLLAMLDPVLTTPWHHVSTWLQNDDPSPFSTAHGTTLWDYAGHEPNLNNFFNEAMASDARLATSVLIHKCTHVFEGLNSLVDVGGGTGTMAKAIAKAFQQMECTVFDLPHVVADLKDDGNLKYAGGDLFEAIPPADAVLLKLLQAQAHVWNSSFNYINSMSLKCAVQLGIPDIIHKHGKPMPLSQMVSALNFTLASLFFEHLAKMSKMKSIFLHLLLDSSKGRIVYIGRKMDMFFTDGVHESELLQAQAHVWNHIFNFINSMSLKCAIQLGIPDIVRNHKKPMTLNQLLTALPIHPTKIQCVHRLMRILVHSGFFAKQKLGQDSQEEGYILTRASLLLLKDNPLSVTPFLLAMLDPVLTTPWHHVSTWLQNDDPSPFSTAHGTTFWDYAGHEPNLNNFFNEAMASDARLATSVLIHKCTHVFEGLNSLVDVGGGTGTMAKAIAKAFQQMECTVFDLPHVVADLKDDGNLKYAGGDLFEAIPPADAVLLKKKLFIIIIIIILKF
>Maker00013289
MTKKKAIFLLILLRDNPLSDVFRWLNTLVDVGGGTETLAKAIAKPFPHLECTIFYLPLVVAYLKGEENLKYVGGDMFEAGGSSSELLHAQAQVWNSAFNYINSMSLKCAVQLGIPDVIHKHGKPMPLSQMVSALNVHPSKAQCIQRLMRILVHSGFFAQPTFGKNEQEEEYFLTPASRLLLKNDPLSAAPFVLLAFIYTGYHQQRLWPIHDTLSDNHGTQCPPKQRSLDSTPYGPFSSHSVFFAQHKLARRRVFPYPASRILLKDKPLKAAPVVLLVVDMAITTSFNFLSTWLQNDDPTLFQTANGKNIWVPYSELIARVVIEAVKRCSRVDVPGLLERWHRMTKANATAFPLRYHVVDTEEV
>Maker00003580
MEEMRREEIMEEEEAEVEIWKYVFGFVNMAVVKCAIELGIAEAIENHGSPMTITELSSTLNCTPSLLHRIMRFLVHHRFFKENPTSQGLVAYEQMPLSRRLIRRGENSMAAFILLESSQVMLAPWHSLSARVIANGMSAFNTAHGKDVWGFAAADAGHNKLINDAMACDARVAVPAIVKGCPEVFDGIETLVDVGGGDGTTLRILVKAFPWIKGINFDLPHVVNVAENFHGVKHVGGDMFDCVPRADATLIKVRNIFFYFFLRYLLQNIDSKAEIQIIKML
>Maker00033255
MRRESIMEEEDAEVEIWKYVFGFVNMAVAKCAIELGIAEAIENHGSPMTISELSSTLNCAPSLLHRIMRFLVHHRFFKEKPTSQGLIAYEQTPLSLRLMKHGENSMAAFILLESSQVMLAPWHSLSARVLANGTSAFNTAHGKDVWGFAAADAGHNKLFNEAMACDARVAVPAIIKGCLQVFDGVETLVDVGGGDGTTLRILVEAFPWIKGINFDLPHVVNVAENFHGVEHVGGDMFDCVPRADAILIKVGSFQMREFVLFKM
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University