Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Theobroma cacao
Species name
Cacao (Theobroma cacao) is a species of eudicot in the family Malvaceae (mallow family).
Species info
Gene sequence info
Theobroma_cacao.OMT.fa
Download
>rna-XM_007043656.2
MDVVCVNGEKHINDHELLQAQAHVWNYLFNFINSMSLKCAIDLGIPDVIQNHGKPMTVTELVAALPINATKASSIYRLMRILVHSGFFAQQKLGNNDQEEGYVLTHASRLLLNGDPLSVTPFLKAMLDPILTKPWHFLGAWFQNDDPTPFDTAHGRTFWDYGGHDPMLSHFFNEGMASDARLVSSILIHKCKGVFQGLNSMVDVGGGIGTVAKAISDAFPHLECTVFDLPRVVAGLQDRGNLKYVGGDMFEAVPAADAVLLKWILHDWNDEECVKILKRCKEAISRGGKGGKAIIIDMVLTEKNHKVNDASIETQLFFDMLMMVLVTGKERNEEEWATLFLAAGFSDYKITPIMGLRSLIEVYP
>rna-XM_018115128.1
MRSKKQNLLEKKEMDSKEAKALVQGQATIWQFMFGFADSMALKCAVELRIADIINSHHRPITLAQIASCIDGSASPDITCLARIMRFLIRRKLFIAHHPSDGGECLYGLTHSSRWLLHDSELSLAPLILMQDHPWLMAPWHYFSRCAREGGIAFKVAHGREVFEFASANPTFNKLFNDAMACTSKVVTRAILSEYKDGFSSIGSLVDVGGGTGGMISEIVRAYPHVKGTNFDLPHVIETAPTYHGVCHIGGDMFQAIPNADAVIMKWILHDWSSEDCIKILRNCRDAIPSETGKVILVECVLQPDGSGLFDDVSLILDLVMLAHSSGGKQRTELEWKKLLNEAGFPRYKVLNIPALPCIIEAYPK
>rna-XM_007043481.2
METSKFGEATLQGQAEIWQYMFSFADSMALKSAVELRIADIIHSHGGAITLSQIASCIGGSPPPDNSYLARIMRLLVRRKVFSVQNPSDGGEPLYGLTLSSTWLIHDSDLTLAPMVLMENHPWQMAPWHCFSECVKEGGIAFKKAHGREIWDFASENPEFNRLFNDGMACTSKIVTRAILTGYKEGFSCIGSLVDVGGGIGGLISEIVKANPHIKGVNFDLPHVVSTAPAYHGVCHVGGDMFHAIPDADAVMMKWILHDWGDEDCIKILRNCRKAIPRENGKVIIVECVLKPDGTDPFDDMGFIFDLLMIAHSSGGKERTELEWKKILEEGGFPRYKIINIPAFASIIEAYPE
>rna-XM_007041657.2
MGDQMKMRGVGVGEDAEAAIDVWRYIFGFVEMAVVKCAIELGIADAIENHGSPMTLSELSAALGCEPSRLHRIMRFMVHNQVFKEEPISQGSIGYAQTPLSRRLTSSGVNSMAALVLLESSPVMLAPWHSLRARVLASGDSPFEAAHGKDIWSYAEANPGHSTLINEAMACAARVSVPAIIEGCPEVFDGLGSLVDVGGGNGTALTTLVKAFPWIRGINFDLPHVVAAATQFDGIENVGGDMFESIPKADAAFFMWVLHDWDDEECTKILKKCREAIPEDKGKVIIVEAVLEDDTDDKLDFLRLMLDMVMMAHTNKGKERTLKEWRYVLGHAGFTRINVKRIRAVQSVIEAYP
>rna-XM_018122993.1
MDQGAIESSFQAQAHLYKHMFNYIGSMSLKCAVQLGIPDIVHSHGESIALSELVSALQIHPAKTNCVYRLMRMLVHSGFFGTTKVHEHDQEEEAYVLTPSSKLLLTDKMNCLSPFVLEVLDPVSVNPFHFLGDWIKGDKNTAFEIAHSLSFWDYVDQNLEFKDLFHEAMARDSQMMNLVIKDYKLIFEGLSSLVDVGGGRGCIAKIISKAYPHLKCTVLDLPHVVANLPESENLNFIGGDMFQYIPSTDAILMKHILHDWSDEDCIKILKKCREAIVRNGAGGKVIIIDVVINEKNDKHELTEAKLFIDMLMMVTVNGRERNEKDFGKLFVEAGFTQYNIMPIFGLKSIMEVYP
>rna-XM_007025452.2
MDQEASESFRAQAHLYKHIFNYIGSMSLKCAVQLGIPDIIHNHGGPITLSELVAALHIDPAKDSCIYRIMRLLVHSGFFATTKVDRDQEEEAYVLTPFSKILLKDKINCLSPFVVSMLGPPMMTPWQFLGDWIQGTKQRPFESANGKAFWDYMDQDPEFKNLFHDAMESDSQMMNLVVKDCKPVFEGLSSLIDVGGGTGTVARVISEAYPQLKCTVFDLPHVVADLPASGNLNFIGGDLLQYIPPADAILLKLVLHAFGDEDCIKILKRCREAIPTQGAKGKVIIIDIVINVKKDEHELTEAKLFFDMLMMVVVTGRERTEQDWQKLFMAAGFTDYKISPLFGLRSLIEVYP
MDVVCVNGEKHINDHELLQAQAHVWNYLFNFINSMSLKCAIDLGIPDVIQNHGKPMTVTELVAALPINATKASSIYRLMRILVHSGFFAQQKLGNNDQEEGYVLTHASRLLLNGDPLSVTPFLKAMLDPILTKPWHFLGAWFQNDDPTPFDTAHGRTFWDYGGHDPMLSHFFNEGMASDARLVSSILIHKCKGVFQGLNSMVDVGGGIGTVAKAISDAFPHLECTVFDLPRVVAGLQDRGNLKYVGGDMFEAVPAADAVLLKWILHDWNDEECVKILKRCKEAISRGGKGGKAIIIDMVLTEKNHKVNDASIETQLFFDMLMMVLVTGKERNEEEWATLFLAAGFSDYKITPIMGLRSLIEVYP
>rna-XM_018115128.1
MRSKKQNLLEKKEMDSKEAKALVQGQATIWQFMFGFADSMALKCAVELRIADIINSHHRPITLAQIASCIDGSASPDITCLARIMRFLIRRKLFIAHHPSDGGECLYGLTHSSRWLLHDSELSLAPLILMQDHPWLMAPWHYFSRCAREGGIAFKVAHGREVFEFASANPTFNKLFNDAMACTSKVVTRAILSEYKDGFSSIGSLVDVGGGTGGMISEIVRAYPHVKGTNFDLPHVIETAPTYHGVCHIGGDMFQAIPNADAVIMKWILHDWSSEDCIKILRNCRDAIPSETGKVILVECVLQPDGSGLFDDVSLILDLVMLAHSSGGKQRTELEWKKLLNEAGFPRYKVLNIPALPCIIEAYPK
>rna-XM_007043481.2
METSKFGEATLQGQAEIWQYMFSFADSMALKSAVELRIADIIHSHGGAITLSQIASCIGGSPPPDNSYLARIMRLLVRRKVFSVQNPSDGGEPLYGLTLSSTWLIHDSDLTLAPMVLMENHPWQMAPWHCFSECVKEGGIAFKKAHGREIWDFASENPEFNRLFNDGMACTSKIVTRAILTGYKEGFSCIGSLVDVGGGIGGLISEIVKANPHIKGVNFDLPHVVSTAPAYHGVCHVGGDMFHAIPDADAVMMKWILHDWGDEDCIKILRNCRKAIPRENGKVIIVECVLKPDGTDPFDDMGFIFDLLMIAHSSGGKERTELEWKKILEEGGFPRYKIINIPAFASIIEAYPE
>rna-XM_007041657.2
MGDQMKMRGVGVGEDAEAAIDVWRYIFGFVEMAVVKCAIELGIADAIENHGSPMTLSELSAALGCEPSRLHRIMRFMVHNQVFKEEPISQGSIGYAQTPLSRRLTSSGVNSMAALVLLESSPVMLAPWHSLRARVLASGDSPFEAAHGKDIWSYAEANPGHSTLINEAMACAARVSVPAIIEGCPEVFDGLGSLVDVGGGNGTALTTLVKAFPWIRGINFDLPHVVAAATQFDGIENVGGDMFESIPKADAAFFMWVLHDWDDEECTKILKKCREAIPEDKGKVIIVEAVLEDDTDDKLDFLRLMLDMVMMAHTNKGKERTLKEWRYVLGHAGFTRINVKRIRAVQSVIEAYP
>rna-XM_018122993.1
MDQGAIESSFQAQAHLYKHMFNYIGSMSLKCAVQLGIPDIVHSHGESIALSELVSALQIHPAKTNCVYRLMRMLVHSGFFGTTKVHEHDQEEEAYVLTPSSKLLLTDKMNCLSPFVLEVLDPVSVNPFHFLGDWIKGDKNTAFEIAHSLSFWDYVDQNLEFKDLFHEAMARDSQMMNLVIKDYKLIFEGLSSLVDVGGGRGCIAKIISKAYPHLKCTVLDLPHVVANLPESENLNFIGGDMFQYIPSTDAILMKHILHDWSDEDCIKILKKCREAIVRNGAGGKVIIIDVVINEKNDKHELTEAKLFIDMLMMVTVNGRERNEKDFGKLFVEAGFTQYNIMPIFGLKSIMEVYP
>rna-XM_007025452.2
MDQEASESFRAQAHLYKHIFNYIGSMSLKCAVQLGIPDIIHNHGGPITLSELVAALHIDPAKDSCIYRIMRLLVHSGFFATTKVDRDQEEEAYVLTPFSKILLKDKINCLSPFVVSMLGPPMMTPWQFLGDWIQGTKQRPFESANGKAFWDYMDQDPEFKNLFHDAMESDSQMMNLVVKDCKPVFEGLSSLIDVGGGTGTVARVISEAYPQLKCTVFDLPHVVADLPASGNLNFIGGDLLQYIPPADAILLKLVLHAFGDEDCIKILKRCREAIPTQGAKGKVIIIDIVINVKKDEHELTEAKLFFDMLMMVVVTGRERTEQDWQKLFMAAGFTDYKISPLFGLRSLIEVYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University