Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Tectona grandis
Species name
Tectona grandis is a species of eudicot in the family Lamiaceae (mint family).
Species info
Gene sequence info
Tectona_grandis.COMT.fa
Download
>Tg06g17720.t1
MGSNINNLGASTVNSDEEESFLFAMQLASASVLPMVLKSAIELDLLELIKKAGPGAFVSPAELAAQLPTTNPEAPVMLDRILRLLTTYSVLNCTLKTLPDGGVQRLYGLAPVCKFLTKNDDGVSNAALLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNQGMSNHSTMTMKKILETYDGFKGLKTVVDVGGGTGATLNMIISKYPSIKGINFDLPHVIEDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCHKFLKTSYDALPENGKVILAECVLPEAPDTGLATRNVVHIDVIMLAHNPGGKERTEKEFQALAKGAGFREFKKVCCAYNCWIMELLK
>Tg11g07510.t1
MNAAGNPITTSSNEEDDHFHCQYAMQLANASVLPMVLKACIELDVLEIIRRTGPNAQLSPSQIACQLPCQNPDAAAAMLDRMLGVLASYSILKCLVVDCENYTNSSHKVDQVQRLYSLALVSKYFLSNANGVSLATMLLANQDKIMMDMWYHTKDAVIEGELPFNRAYGMNASEYIVKNPSYLQLFKASMNDFNSLFMEKLLETYEGFEGLKSIVDVGGGDGSILKTILSKYPAIKGINFDIAVVTQNKATYPDFLAGIEYVAGDMFVGIPKGDAIFLKWMLHSWDDDHCVRILKNCYEALPDHGKVMVVELVVPDSPETTVDIRSKLQLDLIMMNMNPGGKERTEKEFKTLAEAAGFSSIEVTCSAYNFSLVEFYK
>Tg13g10580.t1
MVSVPMSLNAVVRLNVADAIWQGGSNAPLTAAEILSAIASGPTADAENLQRILRMLTSYGIFNEHLSKDNLERRYSLTEVGKTLVTEEDGSSCAALVLQRHQEALMRAWPLVHEAVVDPSSEPFVKANGEPAYIYYGKKPEMNGLMQKAMGGVSAPFMKAFLDNYKGFESVETLVDVGGSAGDCLRMIMNKNPRIKEGINFDLPEVVGIAPKLPGITHVGGDVLKYIPPADAIFLKWVLLTFLDDECKQILKNCYDALPPGGKVIACDPVLPSRTDNSHKTRAILEADIVVMTMYRTKGKHRTELEYKELGASVGFPKFKAKYYVDHFFTILEFQK
>Tg13g10570.t1
MEMESIQSNSPIAVIMELANMISVPMSLNAVVRLNVADAIWQGGSNTPLTAVEILSSTASGPTADAENLQRILRMLTSYGVFNEHLSKDNSERRYSLTDVGKTLVTDENGLSYAPYVLQHHQDALMRAWPLVHEAVVDPSSEPFVKANGEAAYSYYGKKPEMNGLMQKAMAGVSVPFMNALLDSYDGFEGVETLVDVGGSAGDCLRVIMNKNPRIKEGVNFDLPEVVGKAPNIPGITHVGGDMLKSIPPGDAIFLKWVLTTWTDDECKQILKNCYNALPPGGKVTACEPVLPSHTDDSHRSRALLEGDIFVMTIYRSKGKHRTEMEYKELGASVGFPKFKAKLYMDHFFTVLEFQK
>Tg13g10600.t1
MESSQSNSPIIAFMELANMISVPMSLNAVVRLNVADAIWQGGSNAPLTAAEILSTIACGPTADAENLQRILRLLTSYGVFNEHLSKDNSERRYSLTEVGKTLVTDEDGLSYAPLVLQRHQDALMRVWPLVHEAVVDPSSEPFVKVNGEAAYSYYGKQPEMNGLMQKAMAGLSVPFMKAFLDGYDGFEGVETLVDVGGSAGDCLRMIMNKNPRIKIGVNFDLPEVVGIAPKIPGITHVGGDMLKSIPPGDAIFLKWVLLTFPEDEFKQILKNCYNALPPGGKVVACDPVLPSHTDDSHRTRAILENDIMVMTIYRTKGKERTELEYKELGASVGFSKFKAKLYMDHFFTILEFQK
>Tg15g06180.t1
MVSSMGEKLANSTMDYSSSSEEETCLYAMQLVTASVLPAALKSAIELDLLELIKKAGPGAFVSPVELATRMSTTNPEAHVMLDRILRLLATNNILNCSLRQLPDGGGVERLYSLAPVCKYLTRNDDGVSMAPLLLMNQDRVFMETWYHLKDAVLEGGIPFNRAHGMSAFEYAATDPRLNKVFNQAMSQQSTLIMKKILEMYQGFEGLKSLVDVGGGIGASLNMILSKYPSIKGINFDLPHVIQHAPSHPGMEHVSGDMFVTVPRGDAIFMKWICHDWSDAKCLKLLKNCYEALPDNGKVIIAERILSDIPNKALLSSIGFTIDAIMLAYNPGGKERTENEFQALAESSGFREFRKVCCGFSLWIMEFYK
>Tg15g06150.t1
MDESEEEANFLFAMNLACGAVLPMALKSAIELDLLEMIRKAGPATASELAAQLPTTNPQAADMIDRILRLLAVNSVLTCSLKTLPHGGVERRYSLAPVSKFLTENEDGVSVAPVSLLIQDRVFMETWYHLKDTVLEGRVPFDRAHGMNAFEYPATDPRFNKIFNQVMHNQSIIFMKKILKIYRGFEGLKSLVDVGGGVGASLKMIISKYPSIKGINFDLPHVIQDAPPHPGIEHIGGDMFVGVPEADAIFMKWICHDWSDAHCEKLLKNCYRALPENGKVVIAESILPEGPNSGPIDSWTIRGDVQMLAYNPGGKERTEKEFQVLAEKAGFKQFIKVCYAFALWIMELHK
>Tg15g06170.t1
MDSITENNTKIITSMDESEEEATFLFAMQLASGSVLAMVLKSAIELDLLELIKKAGPEASASASELAAQLPTNNHQAADMIDRLLRLLASYSVLTCSLKTLPDGGVERRYALAPVCKFLTRNEDGVSVAPISLMIQDRVLMEPWYHLKDAILEGGVPFDRAYGMNAFEYPATDLRFNKVFNLAMYEQSTIFMKKILEKYKGFEGLKSLVDVGGGTGASLKMIISKYPSIMGINFDLPHVIQDAPPLPGVEHVGGDMFVSVPKAEAIFMKWICHDWSDAHCEKLLKNCYEALPENGKVIVAETIIPEDPNSGWAASRAIIGDVIMLAYNPGGKERTEKEFRTLAKKAGFKQFIKVCHAFNIWIIEFHK
>Tg17g12710.t1
MAGDAGFVSSILTKECKQVFEGFKSLVDVGGGPGFVAKAISDAFPGLKCTVLELPHVVAGLEGADNLTYVSGDMFEFIPHADAVFLKVRVLCLYN
>Tg17g12810.t1
MFESIPHAHAVFLKWIFHDWTDEDCVKILEKCKEATIPVKNNGGKVIIVEMVVDDQKEDRRATKTQLFFDMLMMTGV
MGSNINNLGASTVNSDEEESFLFAMQLASASVLPMVLKSAIELDLLELIKKAGPGAFVSPAELAAQLPTTNPEAPVMLDRILRLLTTYSVLNCTLKTLPDGGVQRLYGLAPVCKFLTKNDDGVSNAALLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNQGMSNHSTMTMKKILETYDGFKGLKTVVDVGGGTGATLNMIISKYPSIKGINFDLPHVIEDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCHKFLKTSYDALPENGKVILAECVLPEAPDTGLATRNVVHIDVIMLAHNPGGKERTEKEFQALAKGAGFREFKKVCCAYNCWIMELLK
>Tg11g07510.t1
MNAAGNPITTSSNEEDDHFHCQYAMQLANASVLPMVLKACIELDVLEIIRRTGPNAQLSPSQIACQLPCQNPDAAAAMLDRMLGVLASYSILKCLVVDCENYTNSSHKVDQVQRLYSLALVSKYFLSNANGVSLATMLLANQDKIMMDMWYHTKDAVIEGELPFNRAYGMNASEYIVKNPSYLQLFKASMNDFNSLFMEKLLETYEGFEGLKSIVDVGGGDGSILKTILSKYPAIKGINFDIAVVTQNKATYPDFLAGIEYVAGDMFVGIPKGDAIFLKWMLHSWDDDHCVRILKNCYEALPDHGKVMVVELVVPDSPETTVDIRSKLQLDLIMMNMNPGGKERTEKEFKTLAEAAGFSSIEVTCSAYNFSLVEFYK
>Tg13g10580.t1
MVSVPMSLNAVVRLNVADAIWQGGSNAPLTAAEILSAIASGPTADAENLQRILRMLTSYGIFNEHLSKDNLERRYSLTEVGKTLVTEEDGSSCAALVLQRHQEALMRAWPLVHEAVVDPSSEPFVKANGEPAYIYYGKKPEMNGLMQKAMGGVSAPFMKAFLDNYKGFESVETLVDVGGSAGDCLRMIMNKNPRIKEGINFDLPEVVGIAPKLPGITHVGGDVLKYIPPADAIFLKWVLLTFLDDECKQILKNCYDALPPGGKVIACDPVLPSRTDNSHKTRAILEADIVVMTMYRTKGKHRTELEYKELGASVGFPKFKAKYYVDHFFTILEFQK
>Tg13g10570.t1
MEMESIQSNSPIAVIMELANMISVPMSLNAVVRLNVADAIWQGGSNTPLTAVEILSSTASGPTADAENLQRILRMLTSYGVFNEHLSKDNSERRYSLTDVGKTLVTDENGLSYAPYVLQHHQDALMRAWPLVHEAVVDPSSEPFVKANGEAAYSYYGKKPEMNGLMQKAMAGVSVPFMNALLDSYDGFEGVETLVDVGGSAGDCLRVIMNKNPRIKEGVNFDLPEVVGKAPNIPGITHVGGDMLKSIPPGDAIFLKWVLTTWTDDECKQILKNCYNALPPGGKVTACEPVLPSHTDDSHRSRALLEGDIFVMTIYRSKGKHRTEMEYKELGASVGFPKFKAKLYMDHFFTVLEFQK
>Tg13g10600.t1
MESSQSNSPIIAFMELANMISVPMSLNAVVRLNVADAIWQGGSNAPLTAAEILSTIACGPTADAENLQRILRLLTSYGVFNEHLSKDNSERRYSLTEVGKTLVTDEDGLSYAPLVLQRHQDALMRVWPLVHEAVVDPSSEPFVKVNGEAAYSYYGKQPEMNGLMQKAMAGLSVPFMKAFLDGYDGFEGVETLVDVGGSAGDCLRMIMNKNPRIKIGVNFDLPEVVGIAPKIPGITHVGGDMLKSIPPGDAIFLKWVLLTFPEDEFKQILKNCYNALPPGGKVVACDPVLPSHTDDSHRTRAILENDIMVMTIYRTKGKERTELEYKELGASVGFSKFKAKLYMDHFFTILEFQK
>Tg15g06180.t1
MVSSMGEKLANSTMDYSSSSEEETCLYAMQLVTASVLPAALKSAIELDLLELIKKAGPGAFVSPVELATRMSTTNPEAHVMLDRILRLLATNNILNCSLRQLPDGGGVERLYSLAPVCKYLTRNDDGVSMAPLLLMNQDRVFMETWYHLKDAVLEGGIPFNRAHGMSAFEYAATDPRLNKVFNQAMSQQSTLIMKKILEMYQGFEGLKSLVDVGGGIGASLNMILSKYPSIKGINFDLPHVIQHAPSHPGMEHVSGDMFVTVPRGDAIFMKWICHDWSDAKCLKLLKNCYEALPDNGKVIIAERILSDIPNKALLSSIGFTIDAIMLAYNPGGKERTENEFQALAESSGFREFRKVCCGFSLWIMEFYK
>Tg15g06150.t1
MDESEEEANFLFAMNLACGAVLPMALKSAIELDLLEMIRKAGPATASELAAQLPTTNPQAADMIDRILRLLAVNSVLTCSLKTLPHGGVERRYSLAPVSKFLTENEDGVSVAPVSLLIQDRVFMETWYHLKDTVLEGRVPFDRAHGMNAFEYPATDPRFNKIFNQVMHNQSIIFMKKILKIYRGFEGLKSLVDVGGGVGASLKMIISKYPSIKGINFDLPHVIQDAPPHPGIEHIGGDMFVGVPEADAIFMKWICHDWSDAHCEKLLKNCYRALPENGKVVIAESILPEGPNSGPIDSWTIRGDVQMLAYNPGGKERTEKEFQVLAEKAGFKQFIKVCYAFALWIMELHK
>Tg15g06170.t1
MDSITENNTKIITSMDESEEEATFLFAMQLASGSVLAMVLKSAIELDLLELIKKAGPEASASASELAAQLPTNNHQAADMIDRLLRLLASYSVLTCSLKTLPDGGVERRYALAPVCKFLTRNEDGVSVAPISLMIQDRVLMEPWYHLKDAILEGGVPFDRAYGMNAFEYPATDLRFNKVFNLAMYEQSTIFMKKILEKYKGFEGLKSLVDVGGGTGASLKMIISKYPSIMGINFDLPHVIQDAPPLPGVEHVGGDMFVSVPKAEAIFMKWICHDWSDAHCEKLLKNCYEALPENGKVIVAETIIPEDPNSGWAASRAIIGDVIMLAYNPGGKERTEKEFRTLAKKAGFKQFIKVCHAFNIWIIEFHK
>Tg17g12710.t1
MAGDAGFVSSILTKECKQVFEGFKSLVDVGGGPGFVAKAISDAFPGLKCTVLELPHVVAGLEGADNLTYVSGDMFEFIPHADAVFLKVRVLCLYN
>Tg17g12810.t1
MFESIPHAHAVFLKWIFHDWTDEDCVKILEKCKEATIPVKNNGGKVIIVEMVVDDQKEDRRATKTQLFFDMLMMTGV
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University