Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Taraxacum kok-saghyz
Species name
Taraxacum kok-saghyz is a species of eudicot in the family Asteraceae (daisy family).
Species info
Gene sequence info
Taraxacum_kok-saghyz.COMT.fa
Download
>evm.model.utg12692.5
MLKLFNSTTNWILHDWSDAHCLKILKNCYEALPDNGKVIVAECMLPEAPDSTPATQNVVHIDVIMLAHNPGGKERTEKDFEALAKGAGFKGFRKAACALNTWVMEFSK
>evm.model.utg12692.4
MESWYHLKDAVVDGGIPFNKAYGMSAFEYHGKDQRFNKVFNSGMFNHSTMTMEKITLVDVGGGIGASLNKIIAKHSSVKGVNFDLPHVIEDAASFPGIEHVGGDMFESVPKEMPFS
>evm.model.utg12692.3
MGSTTAPASFPAESNHDDEAFLFAMNLATASVLPMVVKTAIELNLLEIISKSGAGASLSSSDLASQIPNTNPEAPAMLERICSLLASHSVLTCTLKETDDGGV
>evm.model.utg23284.9
MESLGEDYNMSTEEEGMLKMMEINGGIVLPMVIKTAIELDLFEIMAKTPNGQFSSFDLASSLPKQNPQTPVLIERILRYLASQSILSSTLVRDESGNSKNVYGMTPLSNNYVRNKDGTSHASTVLLIYDKILVDCWYHLKDAIVEGGIPFNKAHGVNAFEYHAMDNRYNQVFNKSMYDNTTIVMKMILEKYKGFEGVKQLVDVGGGLGANLDTILSKYPNIKGINFDLPFVIKDAPSSLGVEHVGGDMFESVPKGDVIFMKWILHDWGDSYCATLLKNCWAALPESGKVVVVEAVIPDLENQPSDATNNDVSKAAIGSDMIMLIANPGGKERTIKEYNTLAKEAGFTSLKIVCSVSMFTIMEFYKSV
>evm.model.utg23284.5
MVAGTILPMVMKTAIELNLFEIMVKVTNNGGGGQFTSSDIVSCLPTQNPQTPIIIERILRYLASKSILTSKISTNENGDTNKSYAMTPICKYFVNNEEGASFASFFLFQNDKVVIDSWYHLKDAVLEGGTPFNKAHGENVFEYQARDKRFGEIFNKAMYGNTAILMKMVLEKYKGFEGVEKLVDVGGGLGATLGIIHSKYPNIKGVNFDMPHVIKDAPLCLGVEHVGGDMFLSVPKGDVIFMKALPEGGKVVVLETIVPEQHPTNNGESEVMSNLDGDMVMLTINPGGKERTAKEYETLAKESGFVSSNIVCSVSFYSIMEFRKKT
>evm.model.utg13838.2
MEIPDGETPPPTGNAARLAIMELANMISVPMSLNAVVRLKVADAIWQNGSNKPLSASEIIPLILPSSDGDPENLQRILRMLTSYGVFNEHISSGDTIQRRYSLTDIGKTLVTDENGLSYGAYVLQHHQEELMKAWAMVHEAVEDSSTEPFVKANGGETAYGMYGKKPEMNDLMLKAMSGVTVPFMKAVLEGYDGFKGVERLVDVGGSAGDCLRMILEKHPHIKEGVNFDLPEVVAKAPNIDGVSHVGGDMFTSIPKGDAIFMKWVLTTWTDDEVKAIMINCFKAIPIGGKLVACEPVLPDQTNDSHRTRALLEGDIFVMTIYRAKGKHRTEQEYCQLGKSAGFTTFRSIYVDDFYTLLEFGK
>evm.model.utg17128.2
MGSTTAPASFPAESNHDDEAFLFAMNLATASVLPMVVKTAIELNLLEIISKSGTGASLSSSDLASQIPNTNPEAPAMLERICSLLASHSVLTCTLKETDDGGVERLYGLAPVCKFLTKNENGVSLAPLLLMNQDKILMESWYHLKDAVVDGGIPFNKAYGMSAFEYHGKDQRFNKVFNSGMFNHSTMTMEKIVDLYDGFNGVKTLVDVGGGIGASLNKIIAKHSSVKGVNFDLPHVIEDAASFPGIEHVGGDMFESVPKGDAIFMKWILHDWSDAHCLKILKNCYEALPDNGKVIVAECMLPEAPDSTPATQNVVHIDVIMLAHNPGGKERTEKDFEALAKGAGFKGFRKAACALNTWVMEFSK
MLKLFNSTTNWILHDWSDAHCLKILKNCYEALPDNGKVIVAECMLPEAPDSTPATQNVVHIDVIMLAHNPGGKERTEKDFEALAKGAGFKGFRKAACALNTWVMEFSK
>evm.model.utg12692.4
MESWYHLKDAVVDGGIPFNKAYGMSAFEYHGKDQRFNKVFNSGMFNHSTMTMEKITLVDVGGGIGASLNKIIAKHSSVKGVNFDLPHVIEDAASFPGIEHVGGDMFESVPKEMPFS
>evm.model.utg12692.3
MGSTTAPASFPAESNHDDEAFLFAMNLATASVLPMVVKTAIELNLLEIISKSGAGASLSSSDLASQIPNTNPEAPAMLERICSLLASHSVLTCTLKETDDGGV
>evm.model.utg23284.9
MESLGEDYNMSTEEEGMLKMMEINGGIVLPMVIKTAIELDLFEIMAKTPNGQFSSFDLASSLPKQNPQTPVLIERILRYLASQSILSSTLVRDESGNSKNVYGMTPLSNNYVRNKDGTSHASTVLLIYDKILVDCWYHLKDAIVEGGIPFNKAHGVNAFEYHAMDNRYNQVFNKSMYDNTTIVMKMILEKYKGFEGVKQLVDVGGGLGANLDTILSKYPNIKGINFDLPFVIKDAPSSLGVEHVGGDMFESVPKGDVIFMKWILHDWGDSYCATLLKNCWAALPESGKVVVVEAVIPDLENQPSDATNNDVSKAAIGSDMIMLIANPGGKERTIKEYNTLAKEAGFTSLKIVCSVSMFTIMEFYKSV
>evm.model.utg23284.5
MVAGTILPMVMKTAIELNLFEIMVKVTNNGGGGQFTSSDIVSCLPTQNPQTPIIIERILRYLASKSILTSKISTNENGDTNKSYAMTPICKYFVNNEEGASFASFFLFQNDKVVIDSWYHLKDAVLEGGTPFNKAHGENVFEYQARDKRFGEIFNKAMYGNTAILMKMVLEKYKGFEGVEKLVDVGGGLGATLGIIHSKYPNIKGVNFDMPHVIKDAPLCLGVEHVGGDMFLSVPKGDVIFMKALPEGGKVVVLETIVPEQHPTNNGESEVMSNLDGDMVMLTINPGGKERTAKEYETLAKESGFVSSNIVCSVSFYSIMEFRKKT
>evm.model.utg13838.2
MEIPDGETPPPTGNAARLAIMELANMISVPMSLNAVVRLKVADAIWQNGSNKPLSASEIIPLILPSSDGDPENLQRILRMLTSYGVFNEHISSGDTIQRRYSLTDIGKTLVTDENGLSYGAYVLQHHQEELMKAWAMVHEAVEDSSTEPFVKANGGETAYGMYGKKPEMNDLMLKAMSGVTVPFMKAVLEGYDGFKGVERLVDVGGSAGDCLRMILEKHPHIKEGVNFDLPEVVAKAPNIDGVSHVGGDMFTSIPKGDAIFMKWVLTTWTDDEVKAIMINCFKAIPIGGKLVACEPVLPDQTNDSHRTRALLEGDIFVMTIYRAKGKHRTEQEYCQLGKSAGFTTFRSIYVDDFYTLLEFGK
>evm.model.utg17128.2
MGSTTAPASFPAESNHDDEAFLFAMNLATASVLPMVVKTAIELNLLEIISKSGTGASLSSSDLASQIPNTNPEAPAMLERICSLLASHSVLTCTLKETDDGGVERLYGLAPVCKFLTKNENGVSLAPLLLMNQDKILMESWYHLKDAVVDGGIPFNKAYGMSAFEYHGKDQRFNKVFNSGMFNHSTMTMEKIVDLYDGFNGVKTLVDVGGGIGASLNKIIAKHSSVKGVNFDLPHVIEDAASFPGIEHVGGDMFESVPKGDAIFMKWILHDWSDAHCLKILKNCYEALPDNGKVIVAECMLPEAPDSTPATQNVVHIDVIMLAHNPGGKERTEKDFEALAKGAGFKGFRKAACALNTWVMEFSK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University