Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Arabis alpina
Species name
Gray rockcress (Arabis alpina) is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Arabis_alpina.HIDH.fa
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>rna-gnl|WGS:JNGA|AALP_mrnaAA1G210500
MDSEIAFDYSPRFRIYKNGRIERLSPETIVPPSLNPENGVVSKDTVYSPEKNLSLRIYLPHKTVEQENKKKKLPLLVYFHGGAFIMESAFSLSYNTFLTSXXXXXDCIAISVDYRRAPEHPIPIAYEDSWEAIKWVFTHISGSGPDDWINEYTDFSRVFIAGDSAGANIAHNMGIRAGTEKLKISGIVLFHPYFWSKAPIDEKETKARRYYEELWEIASPNSVDGGDDPWINVVGSGSDVSGLGCDRVLVMVAEKDVLVRQGLGYVAKLEKSGWVGRVEVMETKDEGHVFHIRNHDTDNAREVVQRFAEFLKD
>rna-gnl|WGS:JNGA|AALP_mrnaAA2G110100
MGATKLTHVTTINPNNTNIHGPVVDEVEGLIRVYKDGHVERSQIVPCVGPSLALELGVACSDVHIDKLNNVWARLYVPMVTKSSSVSKLPLLVYFHGGGFCVGSASWSCYHEFLARLSSRSQCLVMSVNYRLAPENPLPAAYEDGFNAIRWLNKSRNDNLWAKLCDFDRIFLAGDSAGGNIAHRVAAKLAEADLKPMNIEGTILIQPFFGGEARTESERRVENNKSSVLTLAASDAWWRLALRCGANREHPYCKPVKIKTRTLVCVAEMDLLVDRNMEMCDIGNNEKLIKRVVYRGVGHAFQILGKSQLAHTTTLEMLCHIDAFIHHYDQFN
>rna-gnl|WGS:JNGA|AALP_mrnaAA4G063900
MLRTLTFPSSHSLFFHFFRHFPHSLPPLPLSLISITVSDQNLRRKLTPTTLRCISSHSPSDILSEHPPFIRIYKDGHIERLSNTETIPASLTPQNDVITKDIIYSPDLNLSVRLFLPHKSITTSNTNNNKLPLLIYIHGGAWLIGSPFSPIYHNFLTKVTKSSNCLTVSLQYRLAPENPVPAAYEDSWSAIQWIYTHEEDWINEYADFKKVFLAGDSAGGNMCHHMAVKAGEEKLEPRFKGVVIVHPAFWGKDPIDEEDLQDLEESDRIGEVWEKLVSPTSVDGVDDPLFNVVGSGSGSGFGVLGCEKVLVAVAGKDVFVRQGLGYAAKLEKSGWGGEVEVMVEEDEGHCFHLLNPDSENAPKFMKRFVEFITG
>rna-gnl|WGS:JNGA|AALP_mrnaAA4G063700
MEEEEESEIASELLPFVRIYKSGHIKRFSGNEIIPPSLDPLNDVITKDVIYSPDLNLSVRLFLPHKSISDNTKLPLLIYIHGGAWIIESPFSPIYHNYLTEVTKSANCLTVSIQYRRAPENPVPAAYEDSWLAIQWIYSHVNRSGSEDWINEYADFKKVYLAGDSAGGNMCHHMAVKAGEEKLDLRFKGIVIVHPAFWSKDPIDEEDVQDGEIRNGIGEVWEKLVSPNSVDGVDDPLFNVNGYGSGFDELSCEKVLVAVAGKDVFVRQGLGYAAKLEKSEWGGEVEVVLEEDEGHVFHLQNPESEKALKFFKKFVEFITC
>rna-gnl|WGS:JNGA|AALP_mrnaAA4G083200
MEIMKKQVSLELFPWLVVHSDGTLERLVGNEICPPGLDQETKVLSKDIIIDPKTGLAARIYRPDTIQPGQKLPLVLYFHGGAFVIASASFPNYHTSLNKLVGQANIIAISVDYRLAPEHPLPMAYEDSWNALQAIQAGNEPWINDYADLDRFFLVGDSAGANISHHLAFRSKQSDLGTGHTVKIKGIGMIHPYFWGTEPIGLEVTDEARKQMVDGWWKFVCPSDKGSDDPLINPFADGSPEIDGLGCEGVMITVAEKDILSERGKMYYERLVKSKWGGKAEIMETKGKDHVFHIFEPDCDEATEMLRRLALFINQVET
>rna-gnl|WGS:JNGA|AALP_mrnaAA5G109700
MDSEIILDASPFLKLYTNGRVERLMGETTVPPSSTPQNGVVSKDVVYSPDNNLSVRIYLPEKTVEKLPLLVYFHGGGFIIETAFSPTYHTFLTAAVSASNCVAVSVDYRRAPEHPIPISYDDSWTVLKWVFSHIAGSGSEDWLNKHADFNKVFLAGDSAGANIAHHMAVRAAKEKLSPALSDSSSGISGIILVHPYFWSKTPIDDKEYQDVVARGKIDAIWKMASPSSKDGSDDPWINVVQSESVDLSGLGCGKVLVMVAEKDALGRQGWGYAAKLEKCGWKGEVKVVESEGEDHVFHLSKPDCEKALEAMEHFAGFIKGDK
>rna-gnl|WGS:JNGA|AALP_mrnaAA8G060400
MGSLGEQLQVMEDCMGLLQLLSNGTVLRSQTIDLITQQIPLNNHKTVLFKDSIYHKPNNLHLRLYKPISTSNLTDTATRLPVVVFFHGGGFCFGSRSWPLFHNFCHNLASSLHALVVAPDYRLAPEHRLPAAFEDSEAVLTWLRDEAVSGGVDHWFESGPGVDFERVFVLGDSSGGNIAHQLAVRFGSGSIDLKPVKVRGYVLLGPFFGGEERTESEDGPSEASINLDLLDK
>rna-gnl|WGS:JNGA|AALP_mrnaAA8G169600
MAAISFSHHHQSSDNRXXGSHHHRHGPVVEEIEGLIKVFNDGCVERPPIVPTVSPTLHPSAKVTAFDITLSNDIWTRVYIPDAGASPSVTLPLLVYFHGGGFCVGSAAWSCYHDFLTDLAVKARCIVVSVNYRLAPEHRLPRAYEDGVNVVSWLVKQKSNGGCSWLSKCNLSNVFLAGDSAGANIAYQVAVRITTNASGKSVNTLNLKGIILIHPFFGGESRTTSEKQQQHSKSSALTLSASDTYWRLALPRGASRDHPWCNPMVNSAGYLREAKLPATMVFVAEYDIMKDRNLEICRVMRSHGKRVEGVVHGGVGHAFHILDNSLVSRDRIHDMMCRLQNFINP
>rna-gnl|WGS:JNGA|AALP_mrnaAA8G220200
MDSEIVFDNPPNYRVYKNGRIERLKGETFVPPSLTPQNGVVSKDTLYSREKNLSCRIYLPEKISDTDKKLPVLVYVHGGGFIIETAFSPTYHTFLTTTVATAKCLAISVDYRRAPEFPIPIPYQDSWDALKWVFSHISGYGPEHWINKHADFTKVYLAGDSAGANISHHLAIRAKTEKLELEISGMILIHPFFWGKTPIDELEMKNEKKRKRIEGVWGIASPNSVNGADDPLMNVVGSGSDLSRLGCGRVLVMVAGDDFLVRRGLCYAKELEKSEWEGEVEVMEIENEGHVFHLKDPNSDNARRLVKRFAEFINKQDCKQIKCRY
MDSEIAFDYSPRFRIYKNGRIERLSPETIVPPSLNPENGVVSKDTVYSPEKNLSLRIYLPHKTVEQENKKKKLPLLVYFHGGAFIMESAFSLSYNTFLTSXXXXXDCIAISVDYRRAPEHPIPIAYEDSWEAIKWVFTHISGSGPDDWINEYTDFSRVFIAGDSAGANIAHNMGIRAGTEKLKISGIVLFHPYFWSKAPIDEKETKARRYYEELWEIASPNSVDGGDDPWINVVGSGSDVSGLGCDRVLVMVAEKDVLVRQGLGYVAKLEKSGWVGRVEVMETKDEGHVFHIRNHDTDNAREVVQRFAEFLKD
>rna-gnl|WGS:JNGA|AALP_mrnaAA2G110100
MGATKLTHVTTINPNNTNIHGPVVDEVEGLIRVYKDGHVERSQIVPCVGPSLALELGVACSDVHIDKLNNVWARLYVPMVTKSSSVSKLPLLVYFHGGGFCVGSASWSCYHEFLARLSSRSQCLVMSVNYRLAPENPLPAAYEDGFNAIRWLNKSRNDNLWAKLCDFDRIFLAGDSAGGNIAHRVAAKLAEADLKPMNIEGTILIQPFFGGEARTESERRVENNKSSVLTLAASDAWWRLALRCGANREHPYCKPVKIKTRTLVCVAEMDLLVDRNMEMCDIGNNEKLIKRVVYRGVGHAFQILGKSQLAHTTTLEMLCHIDAFIHHYDQFN
>rna-gnl|WGS:JNGA|AALP_mrnaAA4G063900
MLRTLTFPSSHSLFFHFFRHFPHSLPPLPLSLISITVSDQNLRRKLTPTTLRCISSHSPSDILSEHPPFIRIYKDGHIERLSNTETIPASLTPQNDVITKDIIYSPDLNLSVRLFLPHKSITTSNTNNNKLPLLIYIHGGAWLIGSPFSPIYHNFLTKVTKSSNCLTVSLQYRLAPENPVPAAYEDSWSAIQWIYTHEEDWINEYADFKKVFLAGDSAGGNMCHHMAVKAGEEKLEPRFKGVVIVHPAFWGKDPIDEEDLQDLEESDRIGEVWEKLVSPTSVDGVDDPLFNVVGSGSGSGFGVLGCEKVLVAVAGKDVFVRQGLGYAAKLEKSGWGGEVEVMVEEDEGHCFHLLNPDSENAPKFMKRFVEFITG
>rna-gnl|WGS:JNGA|AALP_mrnaAA4G063700
MEEEEESEIASELLPFVRIYKSGHIKRFSGNEIIPPSLDPLNDVITKDVIYSPDLNLSVRLFLPHKSISDNTKLPLLIYIHGGAWIIESPFSPIYHNYLTEVTKSANCLTVSIQYRRAPENPVPAAYEDSWLAIQWIYSHVNRSGSEDWINEYADFKKVYLAGDSAGGNMCHHMAVKAGEEKLDLRFKGIVIVHPAFWSKDPIDEEDVQDGEIRNGIGEVWEKLVSPNSVDGVDDPLFNVNGYGSGFDELSCEKVLVAVAGKDVFVRQGLGYAAKLEKSEWGGEVEVVLEEDEGHVFHLQNPESEKALKFFKKFVEFITC
>rna-gnl|WGS:JNGA|AALP_mrnaAA4G083200
MEIMKKQVSLELFPWLVVHSDGTLERLVGNEICPPGLDQETKVLSKDIIIDPKTGLAARIYRPDTIQPGQKLPLVLYFHGGAFVIASASFPNYHTSLNKLVGQANIIAISVDYRLAPEHPLPMAYEDSWNALQAIQAGNEPWINDYADLDRFFLVGDSAGANISHHLAFRSKQSDLGTGHTVKIKGIGMIHPYFWGTEPIGLEVTDEARKQMVDGWWKFVCPSDKGSDDPLINPFADGSPEIDGLGCEGVMITVAEKDILSERGKMYYERLVKSKWGGKAEIMETKGKDHVFHIFEPDCDEATEMLRRLALFINQVET
>rna-gnl|WGS:JNGA|AALP_mrnaAA5G109700
MDSEIILDASPFLKLYTNGRVERLMGETTVPPSSTPQNGVVSKDVVYSPDNNLSVRIYLPEKTVEKLPLLVYFHGGGFIIETAFSPTYHTFLTAAVSASNCVAVSVDYRRAPEHPIPISYDDSWTVLKWVFSHIAGSGSEDWLNKHADFNKVFLAGDSAGANIAHHMAVRAAKEKLSPALSDSSSGISGIILVHPYFWSKTPIDDKEYQDVVARGKIDAIWKMASPSSKDGSDDPWINVVQSESVDLSGLGCGKVLVMVAEKDALGRQGWGYAAKLEKCGWKGEVKVVESEGEDHVFHLSKPDCEKALEAMEHFAGFIKGDK
>rna-gnl|WGS:JNGA|AALP_mrnaAA8G060400
MGSLGEQLQVMEDCMGLLQLLSNGTVLRSQTIDLITQQIPLNNHKTVLFKDSIYHKPNNLHLRLYKPISTSNLTDTATRLPVVVFFHGGGFCFGSRSWPLFHNFCHNLASSLHALVVAPDYRLAPEHRLPAAFEDSEAVLTWLRDEAVSGGVDHWFESGPGVDFERVFVLGDSSGGNIAHQLAVRFGSGSIDLKPVKVRGYVLLGPFFGGEERTESEDGPSEASINLDLLDK
>rna-gnl|WGS:JNGA|AALP_mrnaAA8G169600
MAAISFSHHHQSSDNRXXGSHHHRHGPVVEEIEGLIKVFNDGCVERPPIVPTVSPTLHPSAKVTAFDITLSNDIWTRVYIPDAGASPSVTLPLLVYFHGGGFCVGSAAWSCYHDFLTDLAVKARCIVVSVNYRLAPEHRLPRAYEDGVNVVSWLVKQKSNGGCSWLSKCNLSNVFLAGDSAGANIAYQVAVRITTNASGKSVNTLNLKGIILIHPFFGGESRTTSEKQQQHSKSSALTLSASDTYWRLALPRGASRDHPWCNPMVNSAGYLREAKLPATMVFVAEYDIMKDRNLEICRVMRSHGKRVEGVVHGGVGHAFHILDNSLVSRDRIHDMMCRLQNFINP
>rna-gnl|WGS:JNGA|AALP_mrnaAA8G220200
MDSEIVFDNPPNYRVYKNGRIERLKGETFVPPSLTPQNGVVSKDTLYSREKNLSCRIYLPEKISDTDKKLPVLVYVHGGGFIIETAFSPTYHTFLTTTVATAKCLAISVDYRRAPEFPIPIPYQDSWDALKWVFSHISGYGPEHWINKHADFTKVYLAGDSAGANISHHLAIRAKTEKLELEISGMILIHPFFWGKTPIDELEMKNEKKRKRIEGVWGIASPNSVNGADDPLMNVVGSGSDLSRLGCGRVLVMVAGDDFLVRRGLCYAKELEKSEWEGEVEVMEIENEGHVFHLKDPNSDNARRLVKRFAEFINKQDCKQIKCRY
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University