Enzyme
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
ROMT
Enzyme
Trans-resveratrol di-O-methyltransferase
Enzyme name
EC:2.1.1.240
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase
Sysname
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction) [RN:R09872];(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene [RN:R09870];(1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene [RN:R09871]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];pterostilbene [CPD:C10287];3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Product
Species information
Strobilanthes cusia
Species name
Strobilanthes cusia is a species of eudicot in the family Acanthaceae.
Species info
Gene sequence info
Strobilanthes_cusia.ROMT.fa
Download
>EVM0011221.1
MAVANEETQFPKYEETSPEQLLQAQAHIWSHMFSFMNSMSLKCALQLGIPDIIHSHTKPMTLSQLVGALGINKAKSQCIFHLMRILTHSKFFIAITIPGTNSDKEEEESYWLTPASLLLLKDKPWTLAPLVLVELDPILTESSHHMSEWILSEDHGLSSFEFTNGKTVWEHAGQDSTFNALFNRAVSYDTLLVTHTLVKECKQVFEGIELVVDVAGGIGTMAKAIVDAFPGIKCTVLDLPHVVAGLEGTSKITYVGGDMFQSIPPADAVLLKLVLHDWNDEDSVRILKKCKEAITKRGNVGGKVIIIDMVVDDLGKGRGNEETQAKLLCDIAMMSAVNGMERSEKEWAKLFVDAGFNTTYKIHSCFAMKSLIEVYL
>EVM0003789.1
MSSDVPSTNKLLEAHIHVCNIISGSIKSSCLKCALELGILDIIHAYGNQMKLSELIDALSINKAKSDHLARVLRVLVHSDFLSRLRIREVNDDSGDDLEEEGYFLTPISRILLRDEPNNLVSYVIGVTDPDLAASPASHLTQWFLGQVPNPFFAAHGMEFWDYLSHNSRMDKLFLHVFEGLTSIVDVGGASGIMASAISNALPHMKCIVLDLPNVVGDMVGKNNLTYVSGDMFKFIPHADGILLKWIMHNWDDEKCVAILKRCRDAIPSDPKGGKVIIIDVVVDENDGPKALETQLALDIIMMMHYNGKERTKKEWTRLFFDGGFTSYKFTKGLGLESIIEVYP
>EVM0000936.1
MALDTNGMHSTQLLLDAQAHIWNHVFNFINSMSLKCTLELGIPDIIHSHGKPMLLYELIDALSIHEGKSLCIERLMRIMIHSKFFVKAKISEEEEDDKEGYWLTPSSVLLLKDEPSSFKPLVLTMLDPILMDPWHQLSKWFGTDHATPFVTTNGETFWERAAHDEKLNMLFNESMGSDARLTSGIIIKDCRDVFDGLKSLVDVGGGTGALAKAITDAFPGLKGTVLDLPHVVADLEGTKDLTYVGGDMFESIPAADAVFMKWILHDWPDDKCVTILKKCKEAITGKEKMGKVIIVDIVLGGDESAGHESMETQLMLDMQMMTLASGKERNEKEWANLFLAAGFTDYKITKVLGLRSLIEVYP
>EVM0014786.1
MPQLSNRQQEAQLQVYNIQSHFVENIMAHSTGMNLSHQELLDAQDHIWNHTFNYINSLSLKCIIQLGIPDMIHKHGKPMMLSELVHALSIHEPKSHCLERLMSLMVHSKFFVKVKISEEEDKEGYWLTPSSLVLLKDDPLSMAPFTQNILDPVFIDLWYSVSKWFVNDDATPFVTTHGTIVWEHMQRNARLNTFFNESMASDAQLVSTILIEDYRHVFEGLKSIVDVGGGTGTIAKALAGAFPGLKCNVLDLPHVVAGLGGSADDVTYIGGDMFEFIPPADCVFMKWILHDWSNEECVKILRKCKDAIPSREKGGKVIIVDMVIGQEKGQKSIETQLLIDMMMMSYTSGRERSEHEWANLFVAAAFTSYKITNNLGLRSLIELFP
>EVM0009191.1
MAVVNGVHSTQELMDAQSHIWNHIFNFINSMSLKCTILLGIPDIIHNHGKPMALSELTHALSINGPKMLCIERLMRIMIHSNFFIKAKISADDDKEGYWLTPSSFLLLKDEPLSVAPFALVMLDPILTDPWHHLSKWFGTDHSTPFVTVHGTTAIEHADLDARFNRMFNEGMASDARFVSSIIVKECRHVFGGLKSIVDVGGGTGTVAKALVDAFPGLKGIVLELPHVITSLETTTDLTYVAGDMFESIPSADAVFMKWILHDWADEECVKILRNCREAIPNKGRGGKVIIIDMVVEDDKKTTDFMRTQLCFDMLMMTVIGGKERTKKEWEALFFAAGFTSCKITDILGFRSLIEVFP
>EVM0005552.1
MALDNGMHSTQVLLDAQAHIWNHIFNFINSMSLKCTLELGIPDIIHNHGKPMLLSELIDALPINEGKSLCIERLMRIMIHSMFFVKAKISEEDDTKEGYWLTPSSLLLLRDEPSSVKPFVLAMLDPILMDPWHQLSEWFGTDHSTPYVTTHGATFWEHAGHDEKLNMLFNKSMASDARLMSSVIIKDCRHVFDGLKSLVDVGGGTGTVTKAIIDAFPGLKGSVFDLPHVVAELEGTKDLTYIGGDMFESIPPAEAVFMKWILHDWPDDKCVTILKKCKEAITGKEKMGKVIIVDMVVDHDEAAGHESMETQLFFDMLMMILASGRERNEKEWENLFLAAGFTSYKITKMLGLRSLIEVYP
>EVM0009463.1
MAFLDATLSTPEILDAQAHIWSHIFNFISSMSLKCTIQLGIPDIIHNHGKPMMLSELTDALSINGEKVLYIERLMRIMIHSKFFTKAKISTNDDKEGYWLTPSSLLLLRDESSSVAPFALAMLDPILTDPWHHLSTWFASDHPTPFVTVYGKSFFEYAGHDARFNKIFNESMASDSRMVASILIKDCKHVFEGLKSMVDVGGGTGAVTKGLVDAFPGLKGIVLELPHVVAGLEGGKDLAYVGGDMFESIPSADAVFMKWTLHSWADEECVKILKNCRKAIPRKENGGKVIIVDMVVDEEIEAELRKTQLCIDMLMMTVNSGKERTKKEWDSLFVAAGFTSYKITNILGLRSLIEVFP
>EVM0008122.1
MALLDGTFSTQDYLDSQAHIWNQIFNFINSMSLKCTIQLGIPDIIHNHGKPMLLSELTDALSINGAKALCIERLMRIMIHSKFFIKAKISTKDDKEGYWLTPSSFLLLRDEPLSVAPFALAMLDPLLMDPWHHLSKWFGTDHPTTFFKVSGMTFWEQAGLDARLNTFFNESLASDCRLVSSVIIKECRHIFYGLKSMVDVGGGTGTMAKALVDGFQGMKCVVLDLPHVVAGLETSKDLTYVGGDMFKSIPSADAVFMKWILHDWPNEECVEILKNCKAAIANKENGGKVIIVDMVLDENIEAERKETQLFFDMLMMNLTSGKERTEKEWANLFATAGFMNYKITKIIGVRSLIEVFP
>EVM0015434.1
MKFLKYEEASTEQVLQAQSHIWNHMFSIINSMSLNCAVQLGIPDIIHSHGKPITLSQLLVALRIDNTKSRFVHRLMRVLCHCKFFTILNIPCTGTDGEEEEEEFYWLTPASHFLLKDGPLTIAPYVRLVMDPTMNKPWDHMSEWLVTREHGSLFEEAYGRSFWEFCGQDSRFNDLFNQGMSSDAGLVMHILLKECKKVFEGIELMVDVGGGAGTAAKAILGTFPNMKCIVLDLPHVVAGLEGTENFTYIGGDMFQSIPPADAILLKWILHDWSDENCKSFCVITTVDVNQFLCIVCV
>EVM0009555.1
MALLNDASKFPEHEEESTEQLLQAQAHIWNTMFSFINSMSLKCAIQLGIPDIIHSHGRPMALSRLVSALPVNQSKAQCIHRLMRILTHSKFFITLNLSNTSSQDEEGEECYWLTPSSRLLLRDRPLNLAPLVLVELDPILTKPWDHMSEWLVSGTLGSAFEVAHGRKFWELAGEELSLNELFNQAMSSDARFIVRTLFKECKQVLEGIELVVDVGGGVGTMAKEIVDEFRGVKCIVLDLPHVVAGLEGTHNLTYIAGDMFESIPPGDAILLKWILHNWKDEDCLRILKKCKEAITEKRKGTDPGKGGGKVIIMDMVLDEFPEKRDNEKTQTQLFFDMAMMALLNGKQRSEKEWAKLFTDAGFTSYKIYPSSGMRPLIEVYP
MAVANEETQFPKYEETSPEQLLQAQAHIWSHMFSFMNSMSLKCALQLGIPDIIHSHTKPMTLSQLVGALGINKAKSQCIFHLMRILTHSKFFIAITIPGTNSDKEEEESYWLTPASLLLLKDKPWTLAPLVLVELDPILTESSHHMSEWILSEDHGLSSFEFTNGKTVWEHAGQDSTFNALFNRAVSYDTLLVTHTLVKECKQVFEGIELVVDVAGGIGTMAKAIVDAFPGIKCTVLDLPHVVAGLEGTSKITYVGGDMFQSIPPADAVLLKLVLHDWNDEDSVRILKKCKEAITKRGNVGGKVIIIDMVVDDLGKGRGNEETQAKLLCDIAMMSAVNGMERSEKEWAKLFVDAGFNTTYKIHSCFAMKSLIEVYL
>EVM0003789.1
MSSDVPSTNKLLEAHIHVCNIISGSIKSSCLKCALELGILDIIHAYGNQMKLSELIDALSINKAKSDHLARVLRVLVHSDFLSRLRIREVNDDSGDDLEEEGYFLTPISRILLRDEPNNLVSYVIGVTDPDLAASPASHLTQWFLGQVPNPFFAAHGMEFWDYLSHNSRMDKLFLHVFEGLTSIVDVGGASGIMASAISNALPHMKCIVLDLPNVVGDMVGKNNLTYVSGDMFKFIPHADGILLKWIMHNWDDEKCVAILKRCRDAIPSDPKGGKVIIIDVVVDENDGPKALETQLALDIIMMMHYNGKERTKKEWTRLFFDGGFTSYKFTKGLGLESIIEVYP
>EVM0000936.1
MALDTNGMHSTQLLLDAQAHIWNHVFNFINSMSLKCTLELGIPDIIHSHGKPMLLYELIDALSIHEGKSLCIERLMRIMIHSKFFVKAKISEEEEDDKEGYWLTPSSVLLLKDEPSSFKPLVLTMLDPILMDPWHQLSKWFGTDHATPFVTTNGETFWERAAHDEKLNMLFNESMGSDARLTSGIIIKDCRDVFDGLKSLVDVGGGTGALAKAITDAFPGLKGTVLDLPHVVADLEGTKDLTYVGGDMFESIPAADAVFMKWILHDWPDDKCVTILKKCKEAITGKEKMGKVIIVDIVLGGDESAGHESMETQLMLDMQMMTLASGKERNEKEWANLFLAAGFTDYKITKVLGLRSLIEVYP
>EVM0014786.1
MPQLSNRQQEAQLQVYNIQSHFVENIMAHSTGMNLSHQELLDAQDHIWNHTFNYINSLSLKCIIQLGIPDMIHKHGKPMMLSELVHALSIHEPKSHCLERLMSLMVHSKFFVKVKISEEEDKEGYWLTPSSLVLLKDDPLSMAPFTQNILDPVFIDLWYSVSKWFVNDDATPFVTTHGTIVWEHMQRNARLNTFFNESMASDAQLVSTILIEDYRHVFEGLKSIVDVGGGTGTIAKALAGAFPGLKCNVLDLPHVVAGLGGSADDVTYIGGDMFEFIPPADCVFMKWILHDWSNEECVKILRKCKDAIPSREKGGKVIIVDMVIGQEKGQKSIETQLLIDMMMMSYTSGRERSEHEWANLFVAAAFTSYKITNNLGLRSLIELFP
>EVM0009191.1
MAVVNGVHSTQELMDAQSHIWNHIFNFINSMSLKCTILLGIPDIIHNHGKPMALSELTHALSINGPKMLCIERLMRIMIHSNFFIKAKISADDDKEGYWLTPSSFLLLKDEPLSVAPFALVMLDPILTDPWHHLSKWFGTDHSTPFVTVHGTTAIEHADLDARFNRMFNEGMASDARFVSSIIVKECRHVFGGLKSIVDVGGGTGTVAKALVDAFPGLKGIVLELPHVITSLETTTDLTYVAGDMFESIPSADAVFMKWILHDWADEECVKILRNCREAIPNKGRGGKVIIIDMVVEDDKKTTDFMRTQLCFDMLMMTVIGGKERTKKEWEALFFAAGFTSCKITDILGFRSLIEVFP
>EVM0005552.1
MALDNGMHSTQVLLDAQAHIWNHIFNFINSMSLKCTLELGIPDIIHNHGKPMLLSELIDALPINEGKSLCIERLMRIMIHSMFFVKAKISEEDDTKEGYWLTPSSLLLLRDEPSSVKPFVLAMLDPILMDPWHQLSEWFGTDHSTPYVTTHGATFWEHAGHDEKLNMLFNKSMASDARLMSSVIIKDCRHVFDGLKSLVDVGGGTGTVTKAIIDAFPGLKGSVFDLPHVVAELEGTKDLTYIGGDMFESIPPAEAVFMKWILHDWPDDKCVTILKKCKEAITGKEKMGKVIIVDMVVDHDEAAGHESMETQLFFDMLMMILASGRERNEKEWENLFLAAGFTSYKITKMLGLRSLIEVYP
>EVM0009463.1
MAFLDATLSTPEILDAQAHIWSHIFNFISSMSLKCTIQLGIPDIIHNHGKPMMLSELTDALSINGEKVLYIERLMRIMIHSKFFTKAKISTNDDKEGYWLTPSSLLLLRDESSSVAPFALAMLDPILTDPWHHLSTWFASDHPTPFVTVYGKSFFEYAGHDARFNKIFNESMASDSRMVASILIKDCKHVFEGLKSMVDVGGGTGAVTKGLVDAFPGLKGIVLELPHVVAGLEGGKDLAYVGGDMFESIPSADAVFMKWTLHSWADEECVKILKNCRKAIPRKENGGKVIIVDMVVDEEIEAELRKTQLCIDMLMMTVNSGKERTKKEWDSLFVAAGFTSYKITNILGLRSLIEVFP
>EVM0008122.1
MALLDGTFSTQDYLDSQAHIWNQIFNFINSMSLKCTIQLGIPDIIHNHGKPMLLSELTDALSINGAKALCIERLMRIMIHSKFFIKAKISTKDDKEGYWLTPSSFLLLRDEPLSVAPFALAMLDPLLMDPWHHLSKWFGTDHPTTFFKVSGMTFWEQAGLDARLNTFFNESLASDCRLVSSVIIKECRHIFYGLKSMVDVGGGTGTMAKALVDGFQGMKCVVLDLPHVVAGLETSKDLTYVGGDMFKSIPSADAVFMKWILHDWPNEECVEILKNCKAAIANKENGGKVIIVDMVLDENIEAERKETQLFFDMLMMNLTSGKERTEKEWANLFATAGFMNYKITKIIGVRSLIEVFP
>EVM0015434.1
MKFLKYEEASTEQVLQAQSHIWNHMFSIINSMSLNCAVQLGIPDIIHSHGKPITLSQLLVALRIDNTKSRFVHRLMRVLCHCKFFTILNIPCTGTDGEEEEEEFYWLTPASHFLLKDGPLTIAPYVRLVMDPTMNKPWDHMSEWLVTREHGSLFEEAYGRSFWEFCGQDSRFNDLFNQGMSSDAGLVMHILLKECKKVFEGIELMVDVGGGAGTAAKAILGTFPNMKCIVLDLPHVVAGLEGTENFTYIGGDMFQSIPPADAILLKWILHDWSDENCKSFCVITTVDVNQFLCIVCV
>EVM0009555.1
MALLNDASKFPEHEEESTEQLLQAQAHIWNTMFSFINSMSLKCAIQLGIPDIIHSHGRPMALSRLVSALPVNQSKAQCIHRLMRILTHSKFFITLNLSNTSSQDEEGEECYWLTPSSRLLLRDRPLNLAPLVLVELDPILTKPWDHMSEWLVSGTLGSAFEVAHGRKFWELAGEELSLNELFNQAMSSDARFIVRTLFKECKQVLEGIELVVDVGGGVGTMAKEIVDEFRGVKCIVLDLPHVVAGLEGTHNLTYIAGDMFESIPPGDAILLKWILHNWKDEDCLRILKKCKEAITEKRKGTDPGKGGGKVIIMDMVLDEFPEKRDNEKTQTQLFFDMAMMALLNGKQRSEKEWAKLFTDAGFTSYKIYPSSGMRPLIEVYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University