Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Striga asiatica
Species name
Witchweed (Striga asiatica) is a species of eudicot in the family Orobanchaceae.
Species info
Gene sequence info
Striga_asiatica.HIDH.fa
Download
>SGA_v2.0_scaffold10T05109
MYIYYVFISFFLFIIHRPTLNVIFFIPIACPTCITVIHCLLLPNLSSFPCLTTIKSPTNYTLFTQNPNFRHRPSPPSAMVKQVQTDLSPVLKLYTDGTVERLFGSAHVPPSPEDASTGVSSKDTVISPEVSARIYLPRIAGGRRKIPILVYYHGGGFCLESAFSFLDHRYINLVSAAAGALVVSVEYRLAPEHPLPAAFIDSWEALKWVCSHGAHSDENTHFEKDEWINDHGDLNQIFVGGDSAGGTIAHNIALRAGSVPLPGNAKVAGAILSHPYFWGSDPIGNEPKEGIEETLLYRLWMFAHPTAAGGIDNPLINPLADPAISGLGCSKLMVSLSEKDQLAARGLAYVEKVKESGWKGEIEVVVVDGEDHCFQIFDPETEKAKDLICRIANFISGSGN
>SGA_v2.0_scaffold14T07030
MATSTPKKIVLDIPPYLRAYDDGTVQRLLGTETTPPADPDPATGVSSKDVVLSPDSGVWARLYRPAGPLPGRLPLVVYFHGGAFCISSAADPVYHHMLNAFVREARVLLVSVDYRRAPESPLPAAYDDSWAALRWVAIRADDWIRDSADLGRVFLAGDSAGANICHHMAMRAGPEGPGMEIAGILLVHPYFWGEAAVGPEAESPAFKSVVDAWWRYVCPSEKGCDDPWINPLVDGAPGLDGLSCGRVLVCVAGNDILRERGKMYYRALVDSGWAGKAQIHETDGAAHVFHIIEPDSEDTKKLIQKCAEFVNGV
>SGA_v2.0_scaffold32T13075
MASAPKEVAFDMSPFFRLFKDGTIDRFGPPGFHPTSEDPNAAVRSKDVQIDPATGLSVRIFAPRRRDPPRRLPVVVYIHGGAFCMGSATSPPFHAFVSTVVERADAIAVSIDYRLAPETPLPAAFEDSWAAFRWVAAHAASSGVGDRDPWLAELADLRRVFVGGESAGATIANDVAVRAGAEPIAGVEIAGVFLIHPFFGGREEDALYRFLCPGSSGRDDDPRLFPAADPRIGGMAGRRVMFLVAEKDFLIQGAWGYYEGLKRSAWAGEVEIVETKGEGHCFHLWNPNSEKAVAVMDRLPGPVSYEINPYIKVFKNGTVQRLSGTTTMPASYDNKTQVHSIDIHIPQAQTQAQEPNNITARLYRPANSTAKHKLPLVVYFHGGAFLTGSAFSPSYHEYLNSLVAKANALAISLNYPLAPEQPLPIAYQDSWHALKWVFSHSGGNGIDREAWLEKYVDFEQVYLAGDGAGANIAHNMAIRVGIDTTDGIRINGMFLNCPFFWGEELVGNEGKCPKKVESIWKHAYPNSTGLDDPSLDPGKDSNLSRLGCERVLVYVDEKDIFRDRGFYYEEVLKGSGWEGNVSVVEVKGEDHIFNIKFPDDPKAGVMLEQLALFLDQGRVGDDGFSSNTVGPAWPTPAVSAQIPPIPKYSGAGFVSQTVVILWNVTNGVEQLVIGCHDHPMTP
>SGA_v2.0_scaffold55T19854
MLAAAQISSFIFFLSIATFHSLSRATPTNSTDPILYEILPFIRVYRNGTIQRFIGQDYAPPSPITPDPGGVLSKDVNVSEKLGLSARIYLPPRKPHRSGKLPLVIYYHGGGFVTESAFSPSYHRHLSLLAARAGVLALSVNYRLAPENPLPAAYEDSWLALKWSLNSTEPWLAKFADFRRVYLGGDSAGANIAHHMAIRVGSEDPGFKISGMFLNCPYFLGKRAIGNESAYPYLKTQMQKLWIYAYPNNGLGLDNPLVNPDKDPNLAKLGCGRVAVFVAGNDGLRFRGRNYVASLEKSGWKGKVKVVEFKGEDHVFNLGKPDSPNALLMLKLLAYFLNGRWI
>SGA_v2.0_scaffold64T21916
MSLVTEAPGFLQVFSDGTVKRFNPKTVDPSATLSDKYKSNDVTIDPSKSITARIFSPSDPVSQPKQQQQQQQKLPVIVYFHGGGFCIGSTTWLGYHVFLGNLSAVAQAYIVSIDYRLAPEHRLPIAYNDCIAALEWLGSASGPWLDRADRSRVFLCGDSAGGNIAHRVAALSVKGNIPGIGIRGLLPIHPFFGSDERTELEAAGGGGSADEVAMNDMFWRLSLPEGSGRGFYGCDYTKEDAEWARFPAVLVFVAGMDFLRERGVMYAEFLKGNGVERVNLIEADEEGHVFHVWNPESEATFVLQKQIAIYLHFLRFSSMFSPSETLLVS
>SGA_v2.0_scaffold90T27679
MPLTKTFFLICSFLIFPLLSTPTTSTNSSPIAYQVLPFIRVFKNGTVERLIGTETVPASYDPTTRVLSKDISIPISRALNITARMYRPANATANSRKLPLLFYIHGGAFFVESAFSPTYHNHLNSLVSKANVVGVSVNYRLAPEHPLPAAYQDSWHALKWVFSLGRDS
>SGA_v2.0_scaffold90T27683
MDSTPIVLAHDFPPFFRIHSTGRVERYHRHDFVPPSHEPLTGVASKDVPISPENGATARIYLPTADPDRKLPLLVYIHGGGFCIESAFSSMYHRYVNAFASRSRSVVVSVEYRLALEHPIPACYEDAHAVVEWIGSHSGPEPGPDA
>SGA_v2.0_scaffold90T27684
MSSAPKEIAVDMSPFFRLFKDGTIDRLSPQQFQPPSDDPTSAVRSKDVQIDPATGLSVRIFAPRRLHDPPRRIPVVVYIHGGAFCVGSAFAPVFHAFVSAVAERAGAVAVSIDYRLAPETPLPAAFDDSWAAFRWIASHAGGVGGPEPWLSELADFGRVFVGGESAGATIASDVAVRAGAEPLSGVGIAGVFLIHPFFGGKEEDRLYRFLCPESSGRDDDPRLYPAVDPRIGGMAGRRVMFFAAEKDLLRDRAWGYYEGLRRSAWAGEVEIMETKEEGHCFHLFNPSSEKAVAIMDRLVAFVTTA
>SGA_v2.0_scaffold90T27680
MVVRSSVSGASFGLRFSGLISIHPFFGAGKPEKLWDFLCPDSKGPDDVRLNPAADPDLLARLGCNRVLVCVAEKDFLRNRGLIYFEGLRKSDFRGSVEFFESVGEGHVFHLLDPVYDGSVVLMDRVVEFISGSQVRAHF
>SGA_v2.0_scaffold112T31553
MGSLAHVVEDCLGLIQVFSDGSIFRSYENLKFPMEVQDDGTAVWKDCFYDEEHELQLRLYKPSSAPAGATCLPVLFFFRGGGFCLGDRTWPNAHNCCLRLAAALGVLLVAPDYRLAPEHRLPAAVEDSRRAVRWLREQAMAGEDEWLQGVDFGRVFVAGDSSGGNLAHHLAVELRRGSPGMEPVRVRGYVLMAPFFGGTERTKSEADGPPEKFLNLDMLDRFWRLSLPIGSTADDPWANPFGPLSPNLESTKLDPILVLVGGCEVMKDRIEDYYKRLKAMGKDIEYVEYEGEEHGFFGNQPFSQVSTKVIQDIAHFMHRNSI
>SGA_v2.0_scaffold124T33558
MAAISLKQNLSPRITPEEPQQRTISVEIPGLIRVFKDGHVERPHLVPCVPPSLAPELGVTCGDATVDQSTSVWARIYLPRPAPQLLPLLVYFHGGGFCVGSASWACYHQFLGQLASAANCVVVSVDYRLAPENPLPAAYDDGAAAVGWVRRQAEEEGSGWWASRCDFKRIFLGGDSAGGNIACHVALRQRPEEVRGLILIQPFFGGEERTGSERQASAGSALTLAAADAYWRMALPEGANRDHPWCNPAAPDVDVLVCVSGMDILRDRNLEFCGRRVERVVYEGVGHAFQILDRSPLAQIRARQMICRIKDFVAM
>SGA_v2.0_scaffold155T37214
MCCLSPLYVNNIPSSYKGQSSREAFTTIPKTHQLESTIQNSQIPLTCSIGPLAAQSRELKHPYFWGSDPIGNKPKECIDQTLLYRLWVFAHPTVVRGIDDQVINALSDPTLSGLGCFKLMVCQLEKDQLTTSGLTYAEKVKESGWKGEIEVVVVDDEDHCFHIFDPETEKAKDMICHIANIISRICFMILVSGGGGGPSFIEVAGTEMYVGTIFKIWDYRR
>SGA_v2.0_scaffold206T41845
MLAAAQISSFIFFLSIATFHSLSQAIAPNSTDPILYDILPFIRVYINDTTPDLGGILSKDVKFSDKLGLPARIYLQFRKPRGFGELPLLIYFHGGGFFTESAFSPSYHRHLSLLAVRVGVVALSVKNRLAPENPLP
>SGA_v2.0_scaffold208T42001
MADESNEELDYEFLPFVKVYKNGHVKRLMGTETTPPGNDPQTGVTSKDVTNIIPQTKVYARIYLPNLTLATTNTRHKLPLVVYFHGGGFLANTPSSSTYHNYLNALAAECQVIAVSVNYRKAPEHPLPIAYEDSWAAFQWVASHCNYDGPEDLLNHHADFGRIFLAGDSAGANIAHNLAMAAGNPDARLKLSIHGIVLIDPYFWGSDTIGSEGMEPGMKAYVDRLWPLVCPSCPMDHPWINPMAESGLGLAGLGCRRVLVSVAEKDILKDRGWHYFHVLSRSGWMGMIEIHEAQGEKHVFHLNDSDCDNSKERMKRMADFFNSSFP
MYIYYVFISFFLFIIHRPTLNVIFFIPIACPTCITVIHCLLLPNLSSFPCLTTIKSPTNYTLFTQNPNFRHRPSPPSAMVKQVQTDLSPVLKLYTDGTVERLFGSAHVPPSPEDASTGVSSKDTVISPEVSARIYLPRIAGGRRKIPILVYYHGGGFCLESAFSFLDHRYINLVSAAAGALVVSVEYRLAPEHPLPAAFIDSWEALKWVCSHGAHSDENTHFEKDEWINDHGDLNQIFVGGDSAGGTIAHNIALRAGSVPLPGNAKVAGAILSHPYFWGSDPIGNEPKEGIEETLLYRLWMFAHPTAAGGIDNPLINPLADPAISGLGCSKLMVSLSEKDQLAARGLAYVEKVKESGWKGEIEVVVVDGEDHCFQIFDPETEKAKDLICRIANFISGSGN
>SGA_v2.0_scaffold14T07030
MATSTPKKIVLDIPPYLRAYDDGTVQRLLGTETTPPADPDPATGVSSKDVVLSPDSGVWARLYRPAGPLPGRLPLVVYFHGGAFCISSAADPVYHHMLNAFVREARVLLVSVDYRRAPESPLPAAYDDSWAALRWVAIRADDWIRDSADLGRVFLAGDSAGANICHHMAMRAGPEGPGMEIAGILLVHPYFWGEAAVGPEAESPAFKSVVDAWWRYVCPSEKGCDDPWINPLVDGAPGLDGLSCGRVLVCVAGNDILRERGKMYYRALVDSGWAGKAQIHETDGAAHVFHIIEPDSEDTKKLIQKCAEFVNGV
>SGA_v2.0_scaffold32T13075
MASAPKEVAFDMSPFFRLFKDGTIDRFGPPGFHPTSEDPNAAVRSKDVQIDPATGLSVRIFAPRRRDPPRRLPVVVYIHGGAFCMGSATSPPFHAFVSTVVERADAIAVSIDYRLAPETPLPAAFEDSWAAFRWVAAHAASSGVGDRDPWLAELADLRRVFVGGESAGATIANDVAVRAGAEPIAGVEIAGVFLIHPFFGGREEDALYRFLCPGSSGRDDDPRLFPAADPRIGGMAGRRVMFLVAEKDFLIQGAWGYYEGLKRSAWAGEVEIVETKGEGHCFHLWNPNSEKAVAVMDRLPGPVSYEINPYIKVFKNGTVQRLSGTTTMPASYDNKTQVHSIDIHIPQAQTQAQEPNNITARLYRPANSTAKHKLPLVVYFHGGAFLTGSAFSPSYHEYLNSLVAKANALAISLNYPLAPEQPLPIAYQDSWHALKWVFSHSGGNGIDREAWLEKYVDFEQVYLAGDGAGANIAHNMAIRVGIDTTDGIRINGMFLNCPFFWGEELVGNEGKCPKKVESIWKHAYPNSTGLDDPSLDPGKDSNLSRLGCERVLVYVDEKDIFRDRGFYYEEVLKGSGWEGNVSVVEVKGEDHIFNIKFPDDPKAGVMLEQLALFLDQGRVGDDGFSSNTVGPAWPTPAVSAQIPPIPKYSGAGFVSQTVVILWNVTNGVEQLVIGCHDHPMTP
>SGA_v2.0_scaffold55T19854
MLAAAQISSFIFFLSIATFHSLSRATPTNSTDPILYEILPFIRVYRNGTIQRFIGQDYAPPSPITPDPGGVLSKDVNVSEKLGLSARIYLPPRKPHRSGKLPLVIYYHGGGFVTESAFSPSYHRHLSLLAARAGVLALSVNYRLAPENPLPAAYEDSWLALKWSLNSTEPWLAKFADFRRVYLGGDSAGANIAHHMAIRVGSEDPGFKISGMFLNCPYFLGKRAIGNESAYPYLKTQMQKLWIYAYPNNGLGLDNPLVNPDKDPNLAKLGCGRVAVFVAGNDGLRFRGRNYVASLEKSGWKGKVKVVEFKGEDHVFNLGKPDSPNALLMLKLLAYFLNGRWI
>SGA_v2.0_scaffold64T21916
MSLVTEAPGFLQVFSDGTVKRFNPKTVDPSATLSDKYKSNDVTIDPSKSITARIFSPSDPVSQPKQQQQQQQKLPVIVYFHGGGFCIGSTTWLGYHVFLGNLSAVAQAYIVSIDYRLAPEHRLPIAYNDCIAALEWLGSASGPWLDRADRSRVFLCGDSAGGNIAHRVAALSVKGNIPGIGIRGLLPIHPFFGSDERTELEAAGGGGSADEVAMNDMFWRLSLPEGSGRGFYGCDYTKEDAEWARFPAVLVFVAGMDFLRERGVMYAEFLKGNGVERVNLIEADEEGHVFHVWNPESEATFVLQKQIAIYLHFLRFSSMFSPSETLLVS
>SGA_v2.0_scaffold90T27679
MPLTKTFFLICSFLIFPLLSTPTTSTNSSPIAYQVLPFIRVFKNGTVERLIGTETVPASYDPTTRVLSKDISIPISRALNITARMYRPANATANSRKLPLLFYIHGGAFFVESAFSPTYHNHLNSLVSKANVVGVSVNYRLAPEHPLPAAYQDSWHALKWVFSLGRDS
>SGA_v2.0_scaffold90T27683
MDSTPIVLAHDFPPFFRIHSTGRVERYHRHDFVPPSHEPLTGVASKDVPISPENGATARIYLPTADPDRKLPLLVYIHGGGFCIESAFSSMYHRYVNAFASRSRSVVVSVEYRLALEHPIPACYEDAHAVVEWIGSHSGPEPGPDA
>SGA_v2.0_scaffold90T27684
MSSAPKEIAVDMSPFFRLFKDGTIDRLSPQQFQPPSDDPTSAVRSKDVQIDPATGLSVRIFAPRRLHDPPRRIPVVVYIHGGAFCVGSAFAPVFHAFVSAVAERAGAVAVSIDYRLAPETPLPAAFDDSWAAFRWIASHAGGVGGPEPWLSELADFGRVFVGGESAGATIASDVAVRAGAEPLSGVGIAGVFLIHPFFGGKEEDRLYRFLCPESSGRDDDPRLYPAVDPRIGGMAGRRVMFFAAEKDLLRDRAWGYYEGLRRSAWAGEVEIMETKEEGHCFHLFNPSSEKAVAIMDRLVAFVTTA
>SGA_v2.0_scaffold90T27680
MVVRSSVSGASFGLRFSGLISIHPFFGAGKPEKLWDFLCPDSKGPDDVRLNPAADPDLLARLGCNRVLVCVAEKDFLRNRGLIYFEGLRKSDFRGSVEFFESVGEGHVFHLLDPVYDGSVVLMDRVVEFISGSQVRAHF
>SGA_v2.0_scaffold112T31553
MGSLAHVVEDCLGLIQVFSDGSIFRSYENLKFPMEVQDDGTAVWKDCFYDEEHELQLRLYKPSSAPAGATCLPVLFFFRGGGFCLGDRTWPNAHNCCLRLAAALGVLLVAPDYRLAPEHRLPAAVEDSRRAVRWLREQAMAGEDEWLQGVDFGRVFVAGDSSGGNLAHHLAVELRRGSPGMEPVRVRGYVLMAPFFGGTERTKSEADGPPEKFLNLDMLDRFWRLSLPIGSTADDPWANPFGPLSPNLESTKLDPILVLVGGCEVMKDRIEDYYKRLKAMGKDIEYVEYEGEEHGFFGNQPFSQVSTKVIQDIAHFMHRNSI
>SGA_v2.0_scaffold124T33558
MAAISLKQNLSPRITPEEPQQRTISVEIPGLIRVFKDGHVERPHLVPCVPPSLAPELGVTCGDATVDQSTSVWARIYLPRPAPQLLPLLVYFHGGGFCVGSASWACYHQFLGQLASAANCVVVSVDYRLAPENPLPAAYDDGAAAVGWVRRQAEEEGSGWWASRCDFKRIFLGGDSAGGNIACHVALRQRPEEVRGLILIQPFFGGEERTGSERQASAGSALTLAAADAYWRMALPEGANRDHPWCNPAAPDVDVLVCVSGMDILRDRNLEFCGRRVERVVYEGVGHAFQILDRSPLAQIRARQMICRIKDFVAM
>SGA_v2.0_scaffold155T37214
MCCLSPLYVNNIPSSYKGQSSREAFTTIPKTHQLESTIQNSQIPLTCSIGPLAAQSRELKHPYFWGSDPIGNKPKECIDQTLLYRLWVFAHPTVVRGIDDQVINALSDPTLSGLGCFKLMVCQLEKDQLTTSGLTYAEKVKESGWKGEIEVVVVDDEDHCFHIFDPETEKAKDMICHIANIISRICFMILVSGGGGGPSFIEVAGTEMYVGTIFKIWDYRR
>SGA_v2.0_scaffold206T41845
MLAAAQISSFIFFLSIATFHSLSQAIAPNSTDPILYDILPFIRVYINDTTPDLGGILSKDVKFSDKLGLPARIYLQFRKPRGFGELPLLIYFHGGGFFTESAFSPSYHRHLSLLAVRVGVVALSVKNRLAPENPLP
>SGA_v2.0_scaffold208T42001
MADESNEELDYEFLPFVKVYKNGHVKRLMGTETTPPGNDPQTGVTSKDVTNIIPQTKVYARIYLPNLTLATTNTRHKLPLVVYFHGGGFLANTPSSSTYHNYLNALAAECQVIAVSVNYRKAPEHPLPIAYEDSWAAFQWVASHCNYDGPEDLLNHHADFGRIFLAGDSAGANIAHNLAMAAGNPDARLKLSIHGIVLIDPYFWGSDTIGSEGMEPGMKAYVDRLWPLVCPSCPMDHPWINPMAESGLGLAGLGCRRVLVSVAEKDILKDRGWHYFHVLSRSGWMGMIEIHEAQGEKHVFHLNDSDCDNSKERMKRMADFFNSSFP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University