Enzyme
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
ROMT
Enzyme
Trans-resveratrol di-O-methyltransferase
Enzyme name
EC:2.1.1.240
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase
Sysname
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction) [RN:R09872];(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene [RN:R09870];(1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene [RN:R09871]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];pterostilbene [CPD:C10287];3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Product
Species information
Stevia rebaudiana
Species name
Stevia rebaudiana is a species of eudicot in the family Asteraceae (daisy family).
Species info
Gene sequence info
Stevia_rebaudiana.ROMT.fa
Download
>Streb.11G005270.1
MSLQNNEPSNNLLESQAHIWNHIFSFIKSMSLKCAVQLEIPDIIDGHGSPMLLSELVEALPINQERTQFVYRLMRILVHSGFFVKQSVSTTKKTNEEEDVGYLLAPSSRLLLKEDPVSLRPYLLALLDPILMDPWQDMSKWFQNDDVIPFHTTHGKSIYNMAGQEPTLNMLFNEAMASDAKLVMSVVLEQCPDVFRGLDSIVDVGGGTGTVAEAIAKAFPDISCMCFDLPHVVKGLDGTRNLTFVVGDMFEAIPNASATLLKWILHNWNDEECLKILKNCKEAIQDGGKLIIIDMVVKVDQDDNKLFETQLFFDMLMMNCLTGRQRSEKDWAKLFHDSGFSDYKITPSLGLRSLIEVYP
>Streb.11G005480.1
MALQDADEQSKCLLQSQAHIWSHIFSFINSMTLKCAIQLQIPDIINHHGAPMLLSELVEALSISKQKSHFVYRLMRILVHSGFFMKQRVSTIGGDENDDDEEEGEGYLLTPTSRLLLKEDPLSMRPFVLAMLDPLLMDPWQHMSQWFKNDDLNPFQTAHGKIIWDFSFQEPMLNKFLNEAMASDARLVAEVILKQRRGVFEGLDSIVDVGGGTGILAKSIAKSFPDVNCICFDLPHVIKGLEGSKNLTYVGGDMFEEIPKADAVFMKWILHDWNDEECIKILKKCKEAIPSKDNGGKVIIIDMVVTNAEQGNKTLETQLRSDMTMMTLATGKERTKEEWEKLFLDADFSDYKITPILGFRSVIEAFP
>Streb.11G007680.1
MRLLVHSGFFVKQSVQGYDKEEGEGYLLTSASRLLLKEDPLSIRPFLISMLDPIIMDPWQQMSKWLKSDDATPVHTTHGKGLWDLIVQEPGFNQLVTEAMANDSRLVMSVVLEQCVGVFQGLDSIVDVGGRTGNVAKAIADAFPNISCICFDLPHVINGLVGSKNLTYLGGDMFEAVPNANAIFMKWTLHDWGDEECKKILKNCKEAIPTKEKGGKLVIIDMVMKLKEGDNDSLETQILFDMLSMNALNGMQRSEQEWAKLFFDAGFSDYTITPILGLRSLIEVYP
>Streb.11G005450.1
MAMQNTELSKNLLHSQAHIWNHIFGFIKSMSLKCAIELQIPDIINRHGSPMLLSELVEALPIKHERIKFVYRLMRILVHSGFFVKQSVSPTIKGYDEAEAEGYLVTPASQLLLKDDPLSLRPFLLAMLDPVLMDPWQHMNQWFQHNDVTPFHTTHGGSLWDLAGQEPRLNQFFNEAMACDAKFVMNVILEQCQGVFQGLESIVDVGGGTGTVSKAIAKAFPNTNCICFDLPHVVDSLVGSKNLSYVGGDMFEAIPNANAILLKWILHDWSDEECKKILKNCKEVIPTRENGGKLVIIDMVLKVDQGDNQLFETQLFFDMLMMTCVTGRERSEKDWAKLFLDSGFSGYKITPVLGLRSLIEVYP
>Streb.5G026000.1
MSMQNDELSKSLLHSQAHIWNHIFSFIKSMSLKCAIQLQIPDIIDCHGSPMLLSELVEALPIKHERTQSVYRLMRILVHSSFFMKQSVSPARASHDDEEEEEEGYLLAPASQLLLKENPLSLRPYLLAMLDPLLMDPWQDMSKWFQNDDVTPFHTTHGRSFYDPAGKEPNLDKLFNESMANDSKLVMSGVLEQCKSVFQGLDSIVDVGGGTGTVTEAIAKAFPNTRCICFDLPHVVNGLVGTTKNLTYVGGDMFEAIPNANAALLKWIMHNWNDEECIKILKNCKAVIPSGGKLIIIDMVVKVDQGDDKLYETQLFFDMVMMTYLTGRQRSEKDWANLFLNGGFSDYKITPILSSRSLIEVYL
>Streb.7G005780.1
MALQNDDQSRVLLDSQAHILNHAYSFVKSMSLKCAIELEIPDIINRHATPMPLSELVNALHISKSRSQHVYRLMRFLVHSGFFATQSLQSTEGVDGEDKEGYLLTPASRLLLKEDALNITPLFLVFLDPIMMDPWQNMSRWFKNDDDINPFHTTHGTMVYELALQEPKLNQSINEGMASDGRLVASVILKNCEGIFQGLDSLVDVGGGTGTFARCIVEAFPNINYINFDLPQVVHGLKGSKNLSFVGGNMFEAIPKAQAVLFKWVFHNWSDKECIEVLKRCKEAIPTKENGGKVIIIEIVVNDKQTSSKMLETQLFFDMFEMTLAKGSQRSEKDWAKLFYDAGFNDYKIFPVLGLRSAIEVYP
>Streb.7G005710.1
MALQNGELSNVLLDSQAHIWNHIFSFICSMSLKCAVELQIPDIINRHGSPMLLSELMEALGLKHERSQFVYRLMRILVHSGFFVKQRVLPKENEEERREGYMLAPTSRLLLKDEPLSIRPFLLAMLDPVLLDPWQQMSKWFQNNDVTPFHTTHGMRLWDLASQEPKLNELFNEGMASDSRLVASVILKHCGNVFEGIDSIVDVGGGTGTVTKAIAEAFPGIRCICFDLPHVVNGLVGGNNLSYVGGDMFESIPNADAVLLKWILHDWSDEDCIKILKQCKESIPSKENGGKLIIIDMVVKVHKEENNLLETQLFFDMLMMTLVGGRERSEKDWAKLFLDAGFSNYKITPILGLRSLIEVYP
>Streb.7G005720.1
MELQSGELSKELLNSQTHIWNHIFSYINSMSLKCAIQLQIPDVIDRHGSPMLLSELVKALNISDDRTQSVYRLMRILVHSGFFVKQTLSATSGGNDEEEGEGYLLAPASRLLLKDEPLSMRPFLLAVLDPIFMDPWQHMSKWFQNDNVTPFYTTHGRMIWDMASLEPNLNQFLNEAMCSDTRLVTSVVSEHCRGVFEGLGSIVDVGGGTGTFSQAIVKAFSNIRCICFDLPHVVAGLVESKNLSYVGGDMFKAIPKADAVLLKSILHDWDDEECMKVLKQCKIAIPSKEKGGKLIIIDMVLKVTKGENELLKTQLLCDMHMMSLVTGRERSEEDWAKLFTIVGFSNYKITPILGLRSLIEVYP
>Streb.Contig05420G000010.1
MALQNHELSKNLLHSQAHIWNHILNFIKSMSLKCAIQLDIPDIIHRHGSPMLLSELVETLAIKKERTQSVYRLMRLLIHSGFFVKQSVQGYDKEEGEGYLLTPASRLLLKEDPLSIGPFVLSILDPIVMDPWQHMSKWLQSDDATPMHTTHGKSLWDLIDQEPTFNRLVTEAMSNDSRLVMSVVLEKCVGVFQGLDSIVDVGGRTGDVAKAIADAFPDISCICFDLPHVVNGLVGSKNLTYVGGDMFEAVPNANAILIKWTLHDWSDEECKKI
>Streb.6G017590.1
MALQNHELSKNLLHSQAHIWNHILNFIKSMSLKCAIQLDIPDIIHRHGSPMLLSELVEALAIKKERTQSVYRLMRLLINSGFFVKQSVQGYDKEEGEGYLLTPASRLLLKEDPLSIGPFVLSMLDPIMMDPWQHISKWLQSDDATPMHTTHGKSLWDLIDQEPTFNRLVTEAMSNDSRLVMSVVLEKCVGVFQGLYSIVDVGGRTGDVAKAIADAFPDISCVCFDLPHVVNGLMGSKNLTYVGGDMFEAVPNANAILIKWTLHDWNDEECKKILKNCKEAIPTKEKGGKLVIIDMVIKLDEGDNQLLETQILFDMLMMNSLTGRERSEHEWAKLFFDAGFNDYKITPILGLRSLIEVYP
>Streb.6G017580.1
MALQNHELSKNLLHSQAHIWNHILNFIKSMSLKCAIQLDIPDIIHRHGSPMLLSELVEALAIKNERTQSVYRLMRLLIHSGFFVKQSVQGYDKEEGEGYLLTPASRLLLKEDPLSIGPFVLSILDPIVTDPWQHMSKWLQSDDATPMHTTHGKSLWDLIDQEPTFNRLVTEAMSNDSRLVMRLDSIVDVGGRTGDVGKAIADAFPDISCVCFDLPHVVNGLVGSKNLTYVGGDMFEAVPNANAILIKWTLHDWSDEECKKILKNCKEAIPTKEKGGKLVIIDMVIKLDEGDNQLLETQILFDMLVMNSLTGRERSEHEWAKLFFDAGFNDYKITPILGLRSLIEVYP
>Streb.Contig03065G000010.1
MRISSLASFPPYILDVCEDIRPYQTVFHAYIESKIAEMALQDADEQSKCLLQSQAHIWSHIFSFINSMTLKCAIQLQIPDIINHHGAPMLLSELVEALSISKQKSHFVYRLMRILVHSGFFMKQRVSTIGGDENDDDEEEGEGYLLTPTSRLLLKEDPLSMRPFVLAMLDPLLMDPWQHMSQWFKNDDLNPFQTAHGKIIWDFSFQEPMLNKFLNEAMASDARLVAEVILKQRRGVFEGLDSIVDVGGGTGILAKSIAKSFPDVNCICFDLPHVIKGLEGSKNLTYVGGDMFEEIPKADAVFMKWILHDWNDEECIKILKKCKEAIPSKDNGGKVIIIDMVVTNAEQGNKTLETQLRSDMTMMTLATGKERTKEEWEKLFLDADFSDYKITPILGFRSVIEAFP
>Streb.Contig05442G000010.1
MALCEQSKELRDSQAHIWNHIFSFINSMSLKCAVELQIPDIIDRHSSPMLLSELVKALGLKQERTQFVYRLMRILIHSGNDEEGGEGYMLTPASRLLLKDKPLSIRPFLLAMLDPLLLDPWQQISKWFQNDDITPFHTTHGMMLWDLAGQEPTLNQFFNEGMASDAKLVTSVILKHCKGVFDGLDSIVDVGGGTGSVAKAIAESFPDINCINFDLAHVVNGLVGSKNLSYVGGDMFEAIPNAHAVLLKWILHDWSDEDCIKILKQCKESIPSKENGGKLIIIDMVVKVHKEENNLLETQLFFDMSEKDWAKLFLDAGFSNYKITPILGLRSLIEVYP
>Streb.Contig04872G000010.1
MFSHFSLYIDKVCRTCQFVSRDGLCKQSKELLDSQAHIWNHIFSFINSMSLKCAVELQIPDIIDRHSSPMLLSELVKALGLKQERTQFVYWLMRILIHSGFFVKQRVSASGGNDEEGGEGYMLTPASRLLLKDKPLSIRPFLLAMLDPLLLDPWQQISKWFQNDDITPFQTTHGMMLWDLAGQEPTLNQFFNEGMASDAKLVTSVILKHCKGVFDGLDSIVDVGGGTGSVAKAIAESFPDIKCINFDLAHVVNGLVGSKNLSYVGGDMFEAIPNAHAVLLKWILHDWRDEDCIKILKQCKESIPSKENGGKLIIIDMVVKVHKEENNLLETQLFFDMLMITLVGGRERSEKDWAKLFLDAGFSNYKITPILGLRSLIEVYP
MSLQNNEPSNNLLESQAHIWNHIFSFIKSMSLKCAVQLEIPDIIDGHGSPMLLSELVEALPINQERTQFVYRLMRILVHSGFFVKQSVSTTKKTNEEEDVGYLLAPSSRLLLKEDPVSLRPYLLALLDPILMDPWQDMSKWFQNDDVIPFHTTHGKSIYNMAGQEPTLNMLFNEAMASDAKLVMSVVLEQCPDVFRGLDSIVDVGGGTGTVAEAIAKAFPDISCMCFDLPHVVKGLDGTRNLTFVVGDMFEAIPNASATLLKWILHNWNDEECLKILKNCKEAIQDGGKLIIIDMVVKVDQDDNKLFETQLFFDMLMMNCLTGRQRSEKDWAKLFHDSGFSDYKITPSLGLRSLIEVYP
>Streb.11G005480.1
MALQDADEQSKCLLQSQAHIWSHIFSFINSMTLKCAIQLQIPDIINHHGAPMLLSELVEALSISKQKSHFVYRLMRILVHSGFFMKQRVSTIGGDENDDDEEEGEGYLLTPTSRLLLKEDPLSMRPFVLAMLDPLLMDPWQHMSQWFKNDDLNPFQTAHGKIIWDFSFQEPMLNKFLNEAMASDARLVAEVILKQRRGVFEGLDSIVDVGGGTGILAKSIAKSFPDVNCICFDLPHVIKGLEGSKNLTYVGGDMFEEIPKADAVFMKWILHDWNDEECIKILKKCKEAIPSKDNGGKVIIIDMVVTNAEQGNKTLETQLRSDMTMMTLATGKERTKEEWEKLFLDADFSDYKITPILGFRSVIEAFP
>Streb.11G007680.1
MRLLVHSGFFVKQSVQGYDKEEGEGYLLTSASRLLLKEDPLSIRPFLISMLDPIIMDPWQQMSKWLKSDDATPVHTTHGKGLWDLIVQEPGFNQLVTEAMANDSRLVMSVVLEQCVGVFQGLDSIVDVGGRTGNVAKAIADAFPNISCICFDLPHVINGLVGSKNLTYLGGDMFEAVPNANAIFMKWTLHDWGDEECKKILKNCKEAIPTKEKGGKLVIIDMVMKLKEGDNDSLETQILFDMLSMNALNGMQRSEQEWAKLFFDAGFSDYTITPILGLRSLIEVYP
>Streb.11G005450.1
MAMQNTELSKNLLHSQAHIWNHIFGFIKSMSLKCAIELQIPDIINRHGSPMLLSELVEALPIKHERIKFVYRLMRILVHSGFFVKQSVSPTIKGYDEAEAEGYLVTPASQLLLKDDPLSLRPFLLAMLDPVLMDPWQHMNQWFQHNDVTPFHTTHGGSLWDLAGQEPRLNQFFNEAMACDAKFVMNVILEQCQGVFQGLESIVDVGGGTGTVSKAIAKAFPNTNCICFDLPHVVDSLVGSKNLSYVGGDMFEAIPNANAILLKWILHDWSDEECKKILKNCKEVIPTRENGGKLVIIDMVLKVDQGDNQLFETQLFFDMLMMTCVTGRERSEKDWAKLFLDSGFSGYKITPVLGLRSLIEVYP
>Streb.5G026000.1
MSMQNDELSKSLLHSQAHIWNHIFSFIKSMSLKCAIQLQIPDIIDCHGSPMLLSELVEALPIKHERTQSVYRLMRILVHSSFFMKQSVSPARASHDDEEEEEEGYLLAPASQLLLKENPLSLRPYLLAMLDPLLMDPWQDMSKWFQNDDVTPFHTTHGRSFYDPAGKEPNLDKLFNESMANDSKLVMSGVLEQCKSVFQGLDSIVDVGGGTGTVTEAIAKAFPNTRCICFDLPHVVNGLVGTTKNLTYVGGDMFEAIPNANAALLKWIMHNWNDEECIKILKNCKAVIPSGGKLIIIDMVVKVDQGDDKLYETQLFFDMVMMTYLTGRQRSEKDWANLFLNGGFSDYKITPILSSRSLIEVYL
>Streb.7G005780.1
MALQNDDQSRVLLDSQAHILNHAYSFVKSMSLKCAIELEIPDIINRHATPMPLSELVNALHISKSRSQHVYRLMRFLVHSGFFATQSLQSTEGVDGEDKEGYLLTPASRLLLKEDALNITPLFLVFLDPIMMDPWQNMSRWFKNDDDINPFHTTHGTMVYELALQEPKLNQSINEGMASDGRLVASVILKNCEGIFQGLDSLVDVGGGTGTFARCIVEAFPNINYINFDLPQVVHGLKGSKNLSFVGGNMFEAIPKAQAVLFKWVFHNWSDKECIEVLKRCKEAIPTKENGGKVIIIEIVVNDKQTSSKMLETQLFFDMFEMTLAKGSQRSEKDWAKLFYDAGFNDYKIFPVLGLRSAIEVYP
>Streb.7G005710.1
MALQNGELSNVLLDSQAHIWNHIFSFICSMSLKCAVELQIPDIINRHGSPMLLSELMEALGLKHERSQFVYRLMRILVHSGFFVKQRVLPKENEEERREGYMLAPTSRLLLKDEPLSIRPFLLAMLDPVLLDPWQQMSKWFQNNDVTPFHTTHGMRLWDLASQEPKLNELFNEGMASDSRLVASVILKHCGNVFEGIDSIVDVGGGTGTVTKAIAEAFPGIRCICFDLPHVVNGLVGGNNLSYVGGDMFESIPNADAVLLKWILHDWSDEDCIKILKQCKESIPSKENGGKLIIIDMVVKVHKEENNLLETQLFFDMLMMTLVGGRERSEKDWAKLFLDAGFSNYKITPILGLRSLIEVYP
>Streb.7G005720.1
MELQSGELSKELLNSQTHIWNHIFSYINSMSLKCAIQLQIPDVIDRHGSPMLLSELVKALNISDDRTQSVYRLMRILVHSGFFVKQTLSATSGGNDEEEGEGYLLAPASRLLLKDEPLSMRPFLLAVLDPIFMDPWQHMSKWFQNDNVTPFYTTHGRMIWDMASLEPNLNQFLNEAMCSDTRLVTSVVSEHCRGVFEGLGSIVDVGGGTGTFSQAIVKAFSNIRCICFDLPHVVAGLVESKNLSYVGGDMFKAIPKADAVLLKSILHDWDDEECMKVLKQCKIAIPSKEKGGKLIIIDMVLKVTKGENELLKTQLLCDMHMMSLVTGRERSEEDWAKLFTIVGFSNYKITPILGLRSLIEVYP
>Streb.Contig05420G000010.1
MALQNHELSKNLLHSQAHIWNHILNFIKSMSLKCAIQLDIPDIIHRHGSPMLLSELVETLAIKKERTQSVYRLMRLLIHSGFFVKQSVQGYDKEEGEGYLLTPASRLLLKEDPLSIGPFVLSILDPIVMDPWQHMSKWLQSDDATPMHTTHGKSLWDLIDQEPTFNRLVTEAMSNDSRLVMSVVLEKCVGVFQGLDSIVDVGGRTGDVAKAIADAFPDISCICFDLPHVVNGLVGSKNLTYVGGDMFEAVPNANAILIKWTLHDWSDEECKKI
>Streb.6G017590.1
MALQNHELSKNLLHSQAHIWNHILNFIKSMSLKCAIQLDIPDIIHRHGSPMLLSELVEALAIKKERTQSVYRLMRLLINSGFFVKQSVQGYDKEEGEGYLLTPASRLLLKEDPLSIGPFVLSMLDPIMMDPWQHISKWLQSDDATPMHTTHGKSLWDLIDQEPTFNRLVTEAMSNDSRLVMSVVLEKCVGVFQGLYSIVDVGGRTGDVAKAIADAFPDISCVCFDLPHVVNGLMGSKNLTYVGGDMFEAVPNANAILIKWTLHDWNDEECKKILKNCKEAIPTKEKGGKLVIIDMVIKLDEGDNQLLETQILFDMLMMNSLTGRERSEHEWAKLFFDAGFNDYKITPILGLRSLIEVYP
>Streb.6G017580.1
MALQNHELSKNLLHSQAHIWNHILNFIKSMSLKCAIQLDIPDIIHRHGSPMLLSELVEALAIKNERTQSVYRLMRLLIHSGFFVKQSVQGYDKEEGEGYLLTPASRLLLKEDPLSIGPFVLSILDPIVTDPWQHMSKWLQSDDATPMHTTHGKSLWDLIDQEPTFNRLVTEAMSNDSRLVMRLDSIVDVGGRTGDVGKAIADAFPDISCVCFDLPHVVNGLVGSKNLTYVGGDMFEAVPNANAILIKWTLHDWSDEECKKILKNCKEAIPTKEKGGKLVIIDMVIKLDEGDNQLLETQILFDMLVMNSLTGRERSEHEWAKLFFDAGFNDYKITPILGLRSLIEVYP
>Streb.Contig03065G000010.1
MRISSLASFPPYILDVCEDIRPYQTVFHAYIESKIAEMALQDADEQSKCLLQSQAHIWSHIFSFINSMTLKCAIQLQIPDIINHHGAPMLLSELVEALSISKQKSHFVYRLMRILVHSGFFMKQRVSTIGGDENDDDEEEGEGYLLTPTSRLLLKEDPLSMRPFVLAMLDPLLMDPWQHMSQWFKNDDLNPFQTAHGKIIWDFSFQEPMLNKFLNEAMASDARLVAEVILKQRRGVFEGLDSIVDVGGGTGILAKSIAKSFPDVNCICFDLPHVIKGLEGSKNLTYVGGDMFEEIPKADAVFMKWILHDWNDEECIKILKKCKEAIPSKDNGGKVIIIDMVVTNAEQGNKTLETQLRSDMTMMTLATGKERTKEEWEKLFLDADFSDYKITPILGFRSVIEAFP
>Streb.Contig05442G000010.1
MALCEQSKELRDSQAHIWNHIFSFINSMSLKCAVELQIPDIIDRHSSPMLLSELVKALGLKQERTQFVYRLMRILIHSGNDEEGGEGYMLTPASRLLLKDKPLSIRPFLLAMLDPLLLDPWQQISKWFQNDDITPFHTTHGMMLWDLAGQEPTLNQFFNEGMASDAKLVTSVILKHCKGVFDGLDSIVDVGGGTGSVAKAIAESFPDINCINFDLAHVVNGLVGSKNLSYVGGDMFEAIPNAHAVLLKWILHDWSDEDCIKILKQCKESIPSKENGGKLIIIDMVVKVHKEENNLLETQLFFDMSEKDWAKLFLDAGFSNYKITPILGLRSLIEVYP
>Streb.Contig04872G000010.1
MFSHFSLYIDKVCRTCQFVSRDGLCKQSKELLDSQAHIWNHIFSFINSMSLKCAVELQIPDIIDRHSSPMLLSELVKALGLKQERTQFVYWLMRILIHSGFFVKQRVSASGGNDEEGGEGYMLTPASRLLLKDKPLSIRPFLLAMLDPLLLDPWQQISKWFQNDDITPFQTTHGMMLWDLAGQEPTLNQFFNEGMASDAKLVTSVILKHCKGVFDGLDSIVDVGGGTGSVAKAIAESFPDIKCINFDLAHVVNGLVGSKNLSYVGGDMFEAIPNAHAVLLKWILHDWRDEDCIKILKQCKESIPSKENGGKLIIIDMVVKVHKEENNLLETQLFFDMLMITLVGGRERSEKDWAKLFLDAGFSNYKITPILGLRSLIEVYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University