Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Spatholobus suberectus
Species name
Spatholobus suberectus is a species of eudicot in the family Fabaceae (pea family).
Species info
Gene sequence info
Spatholobus_suberectus.CHS.fa
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>rna-gnl|WGS:QUWT|mrna.E2542_SST02976
MDTIALHHITSLSLGVKQDEPLHASLLKKKINHLLAHVINLSSNEMAYLEEIREKQRARGPATILAIGTATPPNCVYQADFTDYYFQVTKSEHMTELKAKLKRICKIRIIIYKFMRHLNIVSVCVHVHLHSSLGFTFI
>rna-gnl|WGS:QUWT|mrna.E2542_SST02977
MERVEQIREGKGVATVLAIGTSNPPNFILQADYPDFYFRVTNSDHLHRLKQKFKSICMFLISPSHPLTYIFLE
>rna-gnl|WGS:QUWT|mrna.E2542_SST03544
MVSVDEICKAQRAEGPATVLAIGTTTPPNCFDQITYPDYYFRITNSEHKTELKEKFKRIFFLPS
>rna-gnl|WGS:QUWT|mrna.E2542_SST10673
MGNEGIMKGVTKLRVNPGKATILALGKAFPHQLVMQEYLVDGYFRDTNCDNPELKQKLTRLCKTTTVKTRYVVMSEDILNKYPELAAEGIPTVKQRLEICNEAVTEMAIEASQACIKNWGGSLSDITHLVYVSSSEARLPGGDLYLAKGLGLSPDTQRIMLYFAGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGSDPVLETERPLFELHTAVQEFLPHTEKKIDGRLTEEGISFKLARELPQIIEDNVKGFCDKLMSVVGFQNQEYNKLFWAVHPGGPAILNRIEKRLDLLPEKLSASRRALMDYGNASSNTIVYVLEYMIEEGVKIRKDGREDPEWGLILAFGPGITFEGIVARNLCG
>rna-gnl|WGS:QUWT|mrna.E2542_SST09170
MPQGDSNSSSMQHAAVTRRVPTSGKATILAIGKAFPSQIIPQECLVEGYIRDTKCEDAYIKEKLERLCKNTTVKTRYTVMSKEILDKYPELATEGSPTIKQKLEIANPAVVEMATKASLSCIKEWGRPAQDITHIVYVSSSEIRLPGGDLYLANELGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGANPVLGQESPFMELSYAVQQFLPETHNVIDGRLSEEGINFKLGRDLPQKIEDNIEEFCRKLMAQSNVKEFNDLFWAVHPGGPAILNKLENTLKLSSEKLECSRKALMDYGNVSSNTIFYVMEYMREYLKEGGEEWGLGLAFGPGITFEGILLRSL
>rna-gnl|WGS:QUWT|mrna.E2542_SST12829
MVTVEEIRNAQRSHGPATILAFGTATPSNCVIQADYPDYYFRITNSEHKTDLKEKFKRMCEKSMIKKRYMHLTEEFLKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDAHLDSLVGQALFGDGAAAVIVGADPDPAVERPVFELVSAAQTILPDSEGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLVEAFAPIGISDWNSIFWVAHPGGPAILDQVEEKLRLKEEKLRSTRHVLSEYGNMSSACVLFILDEVRKRSKEEGKGTTGEGLEWGVLFGFGPGLTVETVVLHSVPLEG
MDTIALHHITSLSLGVKQDEPLHASLLKKKINHLLAHVINLSSNEMAYLEEIREKQRARGPATILAIGTATPPNCVYQADFTDYYFQVTKSEHMTELKAKLKRICKIRIIIYKFMRHLNIVSVCVHVHLHSSLGFTFI
>rna-gnl|WGS:QUWT|mrna.E2542_SST02977
MERVEQIREGKGVATVLAIGTSNPPNFILQADYPDFYFRVTNSDHLHRLKQKFKSICMFLISPSHPLTYIFLE
>rna-gnl|WGS:QUWT|mrna.E2542_SST03544
MVSVDEICKAQRAEGPATVLAIGTTTPPNCFDQITYPDYYFRITNSEHKTELKEKFKRIFFLPS
>rna-gnl|WGS:QUWT|mrna.E2542_SST10673
MGNEGIMKGVTKLRVNPGKATILALGKAFPHQLVMQEYLVDGYFRDTNCDNPELKQKLTRLCKTTTVKTRYVVMSEDILNKYPELAAEGIPTVKQRLEICNEAVTEMAIEASQACIKNWGGSLSDITHLVYVSSSEARLPGGDLYLAKGLGLSPDTQRIMLYFAGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGSDPVLETERPLFELHTAVQEFLPHTEKKIDGRLTEEGISFKLARELPQIIEDNVKGFCDKLMSVVGFQNQEYNKLFWAVHPGGPAILNRIEKRLDLLPEKLSASRRALMDYGNASSNTIVYVLEYMIEEGVKIRKDGREDPEWGLILAFGPGITFEGIVARNLCG
>rna-gnl|WGS:QUWT|mrna.E2542_SST09170
MPQGDSNSSSMQHAAVTRRVPTSGKATILAIGKAFPSQIIPQECLVEGYIRDTKCEDAYIKEKLERLCKNTTVKTRYTVMSKEILDKYPELATEGSPTIKQKLEIANPAVVEMATKASLSCIKEWGRPAQDITHIVYVSSSEIRLPGGDLYLANELGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGANPVLGQESPFMELSYAVQQFLPETHNVIDGRLSEEGINFKLGRDLPQKIEDNIEEFCRKLMAQSNVKEFNDLFWAVHPGGPAILNKLENTLKLSSEKLECSRKALMDYGNVSSNTIFYVMEYMREYLKEGGEEWGLGLAFGPGITFEGILLRSL
>rna-gnl|WGS:QUWT|mrna.E2542_SST12829
MVTVEEIRNAQRSHGPATILAFGTATPSNCVIQADYPDYYFRITNSEHKTDLKEKFKRMCEKSMIKKRYMHLTEEFLKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDAHLDSLVGQALFGDGAAAVIVGADPDPAVERPVFELVSAAQTILPDSEGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLVEAFAPIGISDWNSIFWVAHPGGPAILDQVEEKLRLKEEKLRSTRHVLSEYGNMSSACVLFILDEVRKRSKEEGKGTTGEGLEWGVLFGFGPGLTVETVVLHSVPLEG
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University