Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Solanum pennellii
Species name
Solanum pennellii is a species of eudicot in the family Solanaceae (nightshade family).
Species info
Gene sequence info
Solanum_pennellii.COMT.fa
Download
>rna-XM_015215211.1
MGSTSLTQTEDETFLFAMQLASASVLPMVLKSAVELDLLELMAKAGPGASVSPAELAAQLPSKNPDAPVMLDRMLRLLATYSVLNCTLRTLPDGRVERLYSLAPVCKFLTKNADGVSVAPLLLMNQDKVLMQSWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNRGMSDHTTLSIKKILEDYKGFEGLNSIVDVGGGTGATVSMIVSKYPSIKGINFDLPHVIEDAPAYPGVEHIGGDMFVSVPKADAIFMKWICHDWSDEHCLKFLKKCYEAVPANGKVIIAECLLPEVPDTSSSTKNTVHVDVIMLAHNPGGKERTEKEFEALAKGAGFNGFTKACCAYNTWLMEFTK
>rna-XM_015224282.2
MALSMDNIVISNEEEIYMMKAMHIPCGLYLNMVLKAAIELDLFEIIAKSTTQKLSSYEIASQIPTKNPNASSLVLERILRFLASQSFLTCNITKNDDGIVHTSYNLTPLSQSLISDKDGSSIAPFLLLATDPVAVNSWFHFKDAILEGEIPFNKAHGVHAFEYHGKDSRMNGLFNRAMQNVTCTEMKRIVECYNGFQGVKEIIDVGGGLGISLATIISKYPNIKGINFDLPHVIKDAPTYEGIEHVGGDMFKSVPQRELILLKAILHDWDDEYCVKILKNCWRALPKDGKVVVIEQMQPEYPETNLISKNSSSVDMLMMTMLDGGKERTKQQFEDLAKQAGFTVFKIVARAYYCWVIELYK
>rna-XM_015224740.2
MALSMDNIVISNEEEIYMMKAMHIPCGLYLNMVLRAAVELDLFEIIAKSTTQKLSSYEIASQIPTKNPNASSLVLERILRFLASQSLLTCNITKNDDGNVHTSYNLTPLSQSLISDKDGSSLAPFLLLHSESVVVNSCFHLKDAILEGEVPFNKAYGMNAFEYTKKDSRMNGLFNKAMQNVTCIEMKRIVECYNGFKGVKEIIDVGGGLGISLATIISKYPNIKGINFDLPNVIKDAPTYEGIEHVGGDMLKSVPQGELIILKEILHNWDDDDCVKILKNCWRALPNDGKVVVIEQIQPDYPETNLLSKHLFTLDISMMIMFHGGKERTKQQFEDLAKQAGFTSLKVMARAYYYWVIEFYKY
>rna-XM_015223287.2
MEISSTNQSKKIMSKEEEDMLSVMQLPISLALNMVLKVTMELGIFDLLSLNSQLSSSQIASKIPTKNPQAPIMIEKILSFLANQSLLKFTLFKEDDENGPFYSLTPLSRNLVSNNDEMSIAPTFLFINDQAMVNSWFFLKGAILEGEIPFNKAHGMGVFEYHEKNSRYAEVTNKSTQTLNKITITKILETYNGFQEVKQLVDVGGALGSTMASIVSKYPHIKGVNFDLPHVIKDAPVYPGVEHVSGDMFKSVPQGDVIFMKHVIHDWDDDDCIKILKNCWKSLPNFGKVVLVEHIKPNNPQKNDFFSKNAFFLDVLLMVVTHGGKERTMEEFEILAKKSGFSGFKVINSAFLIWIMELYK
>rna-XM_015221838.1
MDMALSMDNIVISNEEEICMMKSMHLPCGLYLNMVIRAAIELDLFEIIAKSTTQKLSSYEIASQIPTKNPNASSLVLERILRFLASQSFLTCNITKNDDGNVHTSYNLTPLSQSLISDKDGTSIAPFLLLNTDPVGVHACFHLKDAILEGEVPFNKAHGVHAYEYHGKDSRMNGVFNKAMQNVTCIDMNRVLECYNGFQGVKEIIDVGGGLGISLASIISKYPNIKGINFDLPHVIKDAPTYEGIEHVGGDMWDSIPQGELIILKAVLHNWDDEDCVKILKNCWRALPNDGKVVVIEQIQPEYPETNPLSKHSFSFDISMMIIFHGGKERTKQQFEDLAKQAGFTSIKVVARAYYSWLIELYKY
>rna-XM_027917954.1
MANNQLPISIGSEKEGNFTYAMQLLSSSVLPFVLHSTIELNVFEILAKANDTQLSSSQIVSKMPCNNPIDAANMLDRMLYVLATYSLLTCSINNNNNVRLYGLSPVGKMFVSDNEDGASLGPLLALLQHKSHNVLYSCDEINHRFGLNDTVLEGGFSFERMHGVNLFEYQKMDPKLSDVFNKAMISHTTLVMKNVLDTYNGFEDIKTLVDVGGGLGINLNMITTKYPTIKGTNFDLPHVVQHAPSYEGVEHVGGDMFESVPKGDAIFMKWILHDWTDSQCVELLKNCYESTPAKNGKVIVVEAILPVQPDPMHTSVVISQTDLIMLAQTSGGKERSQNEFQFLANQAGFNGISFICCASNFWVMEFYK
>rna-XM_015200965.1
MGSTANIQLPTQSENEERNCTYAMQLLSSSVLPFVLHSTIQLDVFEILAKDKAATKLSALEIVSHMPNCKNPDAATMLDRMLYVLASYSLLDCTVVEEGNGVTERRYGLSRVGKFFVRDEDGASMGPLLALLQDKAFINSWFELKDAVLEGGVPFDRVHGVHAFEYPKLDPKFNDVFNQAMINHTTVVMKRILENYKGFENLKTLVDVGGGLGVNLKMITSKYPTIKGTNFDLPHVVQHATSYPGVDHVGGDMFESVPQGDAIFMKWILHDWSDGHCLKLLKNCHKALPDNGKVIVVEANLPVKPDTDTTVVGVSQCDLIMMAQNPGGKERSEQEFRALASEAGFKGVNLICCVCNFWVMEFYK
>rna-XM_015200674.1
MENANGEPSNNNNNDERLAIMELANMISVPMSLNAVVKLKVADAIWGNGSNAPLSPIEILAKIRGPRGGGDAENLQRILRMLTSYGVFKEHVVDDGSQRRYSLTKVGKTLVTDENGLSHGSYVLQHHQDALMRAWTMVHEAVNDSSIEPFAKANGEPAYNYYGKNSEMNSLMLNAMSGVSVPFMKAILQGYDGFQGVKTLVDVGGSGGDCLKMILEKHTNIELGINFDLPEVVEKAPKIPSIKHVGGDMFDYIPKGDAIFMKWVLTTWTDDECKEIMKSCYNALPEKGKFIACEPVLPHHTDDSKRTRALLEGDIFVMTIYRAKGKHRTEEEYRQLGRAAGFNDCKGFYIDHFFTILEFHKS
MGSTSLTQTEDETFLFAMQLASASVLPMVLKSAVELDLLELMAKAGPGASVSPAELAAQLPSKNPDAPVMLDRMLRLLATYSVLNCTLRTLPDGRVERLYSLAPVCKFLTKNADGVSVAPLLLMNQDKVLMQSWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNRGMSDHTTLSIKKILEDYKGFEGLNSIVDVGGGTGATVSMIVSKYPSIKGINFDLPHVIEDAPAYPGVEHIGGDMFVSVPKADAIFMKWICHDWSDEHCLKFLKKCYEAVPANGKVIIAECLLPEVPDTSSSTKNTVHVDVIMLAHNPGGKERTEKEFEALAKGAGFNGFTKACCAYNTWLMEFTK
>rna-XM_015224282.2
MALSMDNIVISNEEEIYMMKAMHIPCGLYLNMVLKAAIELDLFEIIAKSTTQKLSSYEIASQIPTKNPNASSLVLERILRFLASQSFLTCNITKNDDGIVHTSYNLTPLSQSLISDKDGSSIAPFLLLATDPVAVNSWFHFKDAILEGEIPFNKAHGVHAFEYHGKDSRMNGLFNRAMQNVTCTEMKRIVECYNGFQGVKEIIDVGGGLGISLATIISKYPNIKGINFDLPHVIKDAPTYEGIEHVGGDMFKSVPQRELILLKAILHDWDDEYCVKILKNCWRALPKDGKVVVIEQMQPEYPETNLISKNSSSVDMLMMTMLDGGKERTKQQFEDLAKQAGFTVFKIVARAYYCWVIELYK
>rna-XM_015224740.2
MALSMDNIVISNEEEIYMMKAMHIPCGLYLNMVLRAAVELDLFEIIAKSTTQKLSSYEIASQIPTKNPNASSLVLERILRFLASQSLLTCNITKNDDGNVHTSYNLTPLSQSLISDKDGSSLAPFLLLHSESVVVNSCFHLKDAILEGEVPFNKAYGMNAFEYTKKDSRMNGLFNKAMQNVTCIEMKRIVECYNGFKGVKEIIDVGGGLGISLATIISKYPNIKGINFDLPNVIKDAPTYEGIEHVGGDMLKSVPQGELIILKEILHNWDDDDCVKILKNCWRALPNDGKVVVIEQIQPDYPETNLLSKHLFTLDISMMIMFHGGKERTKQQFEDLAKQAGFTSLKVMARAYYYWVIEFYKY
>rna-XM_015223287.2
MEISSTNQSKKIMSKEEEDMLSVMQLPISLALNMVLKVTMELGIFDLLSLNSQLSSSQIASKIPTKNPQAPIMIEKILSFLANQSLLKFTLFKEDDENGPFYSLTPLSRNLVSNNDEMSIAPTFLFINDQAMVNSWFFLKGAILEGEIPFNKAHGMGVFEYHEKNSRYAEVTNKSTQTLNKITITKILETYNGFQEVKQLVDVGGALGSTMASIVSKYPHIKGVNFDLPHVIKDAPVYPGVEHVSGDMFKSVPQGDVIFMKHVIHDWDDDDCIKILKNCWKSLPNFGKVVLVEHIKPNNPQKNDFFSKNAFFLDVLLMVVTHGGKERTMEEFEILAKKSGFSGFKVINSAFLIWIMELYK
>rna-XM_015221838.1
MDMALSMDNIVISNEEEICMMKSMHLPCGLYLNMVIRAAIELDLFEIIAKSTTQKLSSYEIASQIPTKNPNASSLVLERILRFLASQSFLTCNITKNDDGNVHTSYNLTPLSQSLISDKDGTSIAPFLLLNTDPVGVHACFHLKDAILEGEVPFNKAHGVHAYEYHGKDSRMNGVFNKAMQNVTCIDMNRVLECYNGFQGVKEIIDVGGGLGISLASIISKYPNIKGINFDLPHVIKDAPTYEGIEHVGGDMWDSIPQGELIILKAVLHNWDDEDCVKILKNCWRALPNDGKVVVIEQIQPEYPETNPLSKHSFSFDISMMIIFHGGKERTKQQFEDLAKQAGFTSIKVVARAYYSWLIELYKY
>rna-XM_027917954.1
MANNQLPISIGSEKEGNFTYAMQLLSSSVLPFVLHSTIELNVFEILAKANDTQLSSSQIVSKMPCNNPIDAANMLDRMLYVLATYSLLTCSINNNNNVRLYGLSPVGKMFVSDNEDGASLGPLLALLQHKSHNVLYSCDEINHRFGLNDTVLEGGFSFERMHGVNLFEYQKMDPKLSDVFNKAMISHTTLVMKNVLDTYNGFEDIKTLVDVGGGLGINLNMITTKYPTIKGTNFDLPHVVQHAPSYEGVEHVGGDMFESVPKGDAIFMKWILHDWTDSQCVELLKNCYESTPAKNGKVIVVEAILPVQPDPMHTSVVISQTDLIMLAQTSGGKERSQNEFQFLANQAGFNGISFICCASNFWVMEFYK
>rna-XM_015200965.1
MGSTANIQLPTQSENEERNCTYAMQLLSSSVLPFVLHSTIQLDVFEILAKDKAATKLSALEIVSHMPNCKNPDAATMLDRMLYVLASYSLLDCTVVEEGNGVTERRYGLSRVGKFFVRDEDGASMGPLLALLQDKAFINSWFELKDAVLEGGVPFDRVHGVHAFEYPKLDPKFNDVFNQAMINHTTVVMKRILENYKGFENLKTLVDVGGGLGVNLKMITSKYPTIKGTNFDLPHVVQHATSYPGVDHVGGDMFESVPQGDAIFMKWILHDWSDGHCLKLLKNCHKALPDNGKVIVVEANLPVKPDTDTTVVGVSQCDLIMMAQNPGGKERSEQEFRALASEAGFKGVNLICCVCNFWVMEFYK
>rna-XM_015200674.1
MENANGEPSNNNNNDERLAIMELANMISVPMSLNAVVKLKVADAIWGNGSNAPLSPIEILAKIRGPRGGGDAENLQRILRMLTSYGVFKEHVVDDGSQRRYSLTKVGKTLVTDENGLSHGSYVLQHHQDALMRAWTMVHEAVNDSSIEPFAKANGEPAYNYYGKNSEMNSLMLNAMSGVSVPFMKAILQGYDGFQGVKTLVDVGGSGGDCLKMILEKHTNIELGINFDLPEVVEKAPKIPSIKHVGGDMFDYIPKGDAIFMKWVLTTWTDDECKEIMKSCYNALPEKGKFIACEPVLPHHTDDSKRTRALLEGDIFVMTIYRAKGKHRTEEEYRQLGRAAGFNDCKGFYIDHFFTILEFHKS
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University