Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Solanum pennellii
Species name
Solanum pennellii is a species of eudicot in the family Solanaceae (nightshade family).
Species info
Gene sequence info
Solanum_pennellii.OMT.fa
Download
>rna-XM_015232593.2
MSSSESTSSELLHAQAQIWNYIFNFVSSSVIRCAFQLGILDVLYKHDKPMCLSDIFAQLSVVNSSKVSFLPILMQFLVQSGFLNQHEDHYFLTPASRLLAKDDPFNVRSLLLLNHGQAFSKAWPELSDWFQNDSPTPFHTAHGKSLWDYIGEEQPSVLGDIFNDALASDSRLNTNVLITECKHVFEGLTSLVDVGGGTGTVSIAIAKAFPNIKCTVLDLPQVVGDLKGSGNLDFVGGDMFDMIPHANAILLKCVLHDWNDEDCVKILKKCRESIPSRGKGGKVIIIDTVLEDPKQSNEFVRAQHNMGMLMMVLFAATERTEKEWEKLFSEAGFTEYKIFPALGLRSLIEIYP
>rna-XM_015232704.2
MAKEINGLNHIGSGEEEESQVQADIWRCISGFAEMAVAKCAIELGISEFLESHQEPVPLRQLSSALGCSASSLHRILRFLINRGMFKLVSITGNGEMGYVQTPVSRLLKRDGENSMAALVLLESSPVMLAPWHYLSARVLSKENSTGAFCAAHGKDLWEYAKTNPEHSKLVNDALACHARVTMHAIINNCGEIFKGIESLVDVGGGNGTTVGMLVKAFPWINGINFDLPHVVSVAPPCHGVVHVEGDMFHSVPKAQAVFLMSVLHDWGDDECIHILKKCIEAIPKDTGKVIIVEAVIDEKIGKGKNLKDVGLMLDMIMMAHTSNGKERSAKEWDHILSAAGFSSHSIRQIPAIEPVILAYP
>rna-XM_015227484.2
MAKETNELIMSQVQADIWRCISGFTEMAVAKCAIELGISDFLESHQEPVPLRQLSTALGCSASSLYRILRFLINRGMFKLVSTGNGEMGYVQTPVSRLLKRDGENSMAALVLLESSPVMLAPWHYLSARVLSKENSTGAFCAAHGKDLWEYAKTNPEHSKLINDALACHARVTMHAIMNNCAEIFKGIESLVDVGGGNGTTVGMLVKAFPWINGINFDLTHVVSVAPPCHGVVHVEGDMFHSVPKAQAAFLMWVLHDWSDEECIKILKKCIEAIPKERGIVIIVEAVVDEKIGKEKGVKDVGLMLDMIMMAHTSNGKERSAKEWDHILSAAGFSSHSIRQTTAIEPLILAYP
>rna-XM_015209772.2
METNNNVERVSELFKAQAHIYKHVFAYANSMALNCAIQLGIPDIIHNHKKPITLPDLLSGLKLHSSKSNAIHRLMRLLVHAQFFDIIKLEENSETEGYVLTTSSRLLLKSEIPNLSPCVRLMVDPVFVTPWQLLEGWFHKNEEATPFETAHGMPMWDLCAQNPIFDRVFNEAMASDSQMMRLVVKDCREVFEGLSSLVDVGGGTGIVAKTILEAIPHLKCTVLDLPHVVANMPQTENLIYVGGNMFQCIPHADAILLKHVMHNWSDEDCVKILKRCREAIEDKDEGRKGKVLIIDMVLGRDEEEANMTEVKLIFDVLMMVVATGRQRTEKEWEKLFTEAGFMSYKITPLLGLRSLIQVFP
>rna-XM_015209873.2
MDVPMSSEMFEAQAHIYKHAFSFANSMVLGCAIQLGIPDVIHSHKQPMTLSQLVSELKLPLEKSEAIHRLMRLLVYSGFFATTDFLDENSESQQGYVLTPSSKLLLKSEIPNLSPFARAMIDPVMVNPWQSLGDWFLGNETTPFETAHGAPMWKFCDQNPRFNNVFNEAMASDSQMMCLVVNDCKQVFQEIDSLVDVGGGTGIIANTILAAFPHLKCTVLDLPHVVANMPDTHNVQYVGGDMFHSIPSADAILFKHVMHNWSDENCVKILKRCGEAIKDKNEGRKGKVLIIDMVLDRDKEEANMTEVKLIFDVLMMVLLTGRERTEKEWEKLFLEAGFMSYKITPLFGLRSLIEVFP
>rna-XM_027915458.1
MSCHLSNFSYKYRFHSPNITHLKEKMALSDNIGDETNEVLAAQAHIANHVFNYINSMSLKCAIQLGIPDIIHNHGRAMTQSDLVNALPINKSKGHDCIYRLMRILIHAGFFTQGEEGYLLTPTSRLLLKNGPLSLAPFVQAQLDPVLMDPWHSLGEWFANEDSTPFATAHGKPLFEYAGDDQRLNNLFNEAMGCDARLIMSVLIKNGKGVFEGLKSLVDVGGGIGTVAKAISNAFPELQCSVFDLPHVVEGLEGGKNLSYIGGDMFKFVPSADAVLLKWVLHDWSDENCVKILKKCKEAIPSKENGGKVIVIDIVIDNQKGDNKSFETQLFSDVLMMVHVSGKERNEQEWAKLFSDAGFSDYKISPILGLRSVIEVYP
>rna-XM_015222142.2
MANNNNICAYELIEAEAQSWDYILSYLRPSCIKCAIQLGIPDILHKNAHPIMSLSDLIAALPNLNPSKTTFIPILMRVLVDFGLFNYHHQQGDGYSLTSVGRLLVENHLSGSNRSFFLFAQHPVVLNTAASVGDWLKDDLRTAFETAHGKSHWDYCGEDAEFNGVFNDAMAGDSRFISNLLISDCCAGVFEGLTSLVDIGGGTGAVAMAIAGAFPSLKCIVLDLPHVIADRKGSGNLEFVAGSMFDKIPNANAILLKWILHNWNDEDCVKLLKKCKESISSKENGGKVIIIDMIMEDNCNNKQLVQSQHLMDLIMRITCASKERTEKEWEKLFLEAGFNGYKIITSLGIRSLIEIYP
>rna-XM_015222455.2
MANKNNMYANELIEAEAQSWDYILTYLRPPCVRCAIQLGIPDILHKNADPIMSLSDLIAALPNLNPSKTTFIPILMRVLVDLGLFNYHHQQGDGYSLTSVGRLFVENDPSNKRSIFTFLTQFEIVDSMSDWLRNDLPTAFETAHGKSIWDYCAGESEYSGVFNDAMASDSKLISNLLISDCCSGVFEGLTSLVDVGGGTGTVAMAIAGAFPSLKCAVLDLPHAIGDRKGTQNLEFVAGNMFDKIPHANAILLKWILHDWNDEDCVKILKKCKESIPSKEKGGKLIIIDIVMEDNCSNNERLVQSQHLMDLLVRIIYASKERSNKEWEKLFLDAGFSGYKIITSLGLRSLMEVYP
>rna-XM_015230944.2
MALPNNIGDETNEVLAAQAHILNHVLNYVISMSLKCAIQLEIPDIIYSHGRAMTLSDLLNALPINKLKGHKCIYRLMRILIHVDFFIQGEEGYLHTPTSRLLLKNEPLSLSPFVQAELDPILMDPWHSLTEWFMNGDSTTFATTHGKLLFEYAGDDPRVNRLLNEAMGSDARLIIRVLIKNGKGVFEGLKSLVDVGGGTRTVARAISNAFPELKCSVFDLPHVVEGLEGGNNLSYIGGDMFKSVPSAHAILLKWILHDWSDEDCVKILKKCKEAIPSKENGGKVIVIDIVIDNEKRDNKSFETQLFSDVLMMVHVSGKERNEQEWAKLFSDSGFSHYNISHILGLRSVIEVYP
>rna-XM_015233922.2
MADHNENLTPSELLQAETQSWNQLYFFIEHVALKCALQLDIPNVITKHDKPMTISKLMSSLPISPSKYPYFHRLTRILIHYGFLILQKHDDNNVDDDKGCYSLAPADCYVAKDGPWNSMEDQDTFFFKAWSCLGDWFKNDDPSAFYTAYGDLFWSKLSSDSSTGNWFNENMSRDSRSFMNVLIGNEYKDVFKGLTSLVDVGGGTGTVAMSIAKSFPDMKCIVLDLPPVVANLQGSENLEFVAGDMFQKIPPANAVLLKSILHDWNDEECVKILKNCKEALRGSGKVIIIDMVMENTELDDETVHAKLFIDMLMMVFVGSKERNKKEWEKLFLISGFTSYKIVLTLGLRSVIELYP
>rna-XM_015233317.2
MVVPIVGEHETEILHAQTHIWNHIFSFINSMSLKSAIQLNIPDIIHKHGKPMTLDELANALSINHSKITHLRRLMRILVHSGFFLKSGSGSGSESGSVEGGYVLAPPARLLLKDEPLTVTPFLLAMLDPILVKPWHNVSEWFTSDEPTAFEVAHGRTFWDYAGHEPRLNHFFNDAMASDAKLVMSVVMKYSKDVFEGLNSIVDVGGGTGTVAKTIAKTFPNLQCTVFDLPHVVEGLEGSDNLTYVGGDFFVSIPHAEALLLKWILHDWSDEESVKILKKCKEAIPSKEKGGKVIIIDMMVDNKIGDDESIETQIFFDMLMMVLVTGRERSEKGWAKIFFEAGFSDYKVTPILGLRSLIEVYP
>rna-XM_015204456.2
MTLPNDNMTREMLAAQAHIWNHTFSYVKSMSLKCAIQLGIPDIIHSHGRAMTLPDLVDALPINNNAKTLDYIFRLMRILIHGGFFNQIKVNDTEEGYLLTPASCLLLKDEPLSQVAFVQMELDPNFIDPWHSLSKWIRSDNDDSSTPFAIAHGKSLFEYDERQPNINRQFNEIMASDSRLLISVVIKNCRGVFEGLKSFVDVGGGIGIVAKVIADAFLDMNCIVFDLPHVIEGCEGSKNIIYVGGDMFKFIPYADAILLKWILHDWSDEKCIKILKKCKDAIPSKEKGGKVIIIDMVLMDHNLENVDDKSYETQLFFDMLMMVHVSGKERNQQDWAKLISGAGFSDYNIIPILGLRSIIDVFP
>rna-XM_015204394.2
MEKETNGKAKRNDEKIQESHEAQANMWKFVFGFTEMAVIKCAIELGIADFLEKNQEPISLNQLSIALGCCSTSLYRILRFLINRGIFKETSTKSGKNGYVQTPLSRLLIKEGENSMAAFLLFESSPVMLAPWHNLSARISSKDNSTPAFDAAHGKDIWKYAEADSGLSNLLNNAMACDAKVTVSAIIDSCPEIFEGVNTMVDVGGGDGTTLRLLVEAFPWINGINFDLPHVASVAPHAIGVVHVGGDMFNYVPKADAAFLMWVLHDWGDEECIQILTKCREAIPKDKGKVIILEAIIGEKEENNIIRGSNNEKLKDVGLMLDMVMMAHTSNGKERTSKEWAYVLNEAGFGRHTISHINAVQSVIQAYPS
MSSSESTSSELLHAQAQIWNYIFNFVSSSVIRCAFQLGILDVLYKHDKPMCLSDIFAQLSVVNSSKVSFLPILMQFLVQSGFLNQHEDHYFLTPASRLLAKDDPFNVRSLLLLNHGQAFSKAWPELSDWFQNDSPTPFHTAHGKSLWDYIGEEQPSVLGDIFNDALASDSRLNTNVLITECKHVFEGLTSLVDVGGGTGTVSIAIAKAFPNIKCTVLDLPQVVGDLKGSGNLDFVGGDMFDMIPHANAILLKCVLHDWNDEDCVKILKKCRESIPSRGKGGKVIIIDTVLEDPKQSNEFVRAQHNMGMLMMVLFAATERTEKEWEKLFSEAGFTEYKIFPALGLRSLIEIYP
>rna-XM_015232704.2
MAKEINGLNHIGSGEEEESQVQADIWRCISGFAEMAVAKCAIELGISEFLESHQEPVPLRQLSSALGCSASSLHRILRFLINRGMFKLVSITGNGEMGYVQTPVSRLLKRDGENSMAALVLLESSPVMLAPWHYLSARVLSKENSTGAFCAAHGKDLWEYAKTNPEHSKLVNDALACHARVTMHAIINNCGEIFKGIESLVDVGGGNGTTVGMLVKAFPWINGINFDLPHVVSVAPPCHGVVHVEGDMFHSVPKAQAVFLMSVLHDWGDDECIHILKKCIEAIPKDTGKVIIVEAVIDEKIGKGKNLKDVGLMLDMIMMAHTSNGKERSAKEWDHILSAAGFSSHSIRQIPAIEPVILAYP
>rna-XM_015227484.2
MAKETNELIMSQVQADIWRCISGFTEMAVAKCAIELGISDFLESHQEPVPLRQLSTALGCSASSLYRILRFLINRGMFKLVSTGNGEMGYVQTPVSRLLKRDGENSMAALVLLESSPVMLAPWHYLSARVLSKENSTGAFCAAHGKDLWEYAKTNPEHSKLINDALACHARVTMHAIMNNCAEIFKGIESLVDVGGGNGTTVGMLVKAFPWINGINFDLTHVVSVAPPCHGVVHVEGDMFHSVPKAQAAFLMWVLHDWSDEECIKILKKCIEAIPKERGIVIIVEAVVDEKIGKEKGVKDVGLMLDMIMMAHTSNGKERSAKEWDHILSAAGFSSHSIRQTTAIEPLILAYP
>rna-XM_015209772.2
METNNNVERVSELFKAQAHIYKHVFAYANSMALNCAIQLGIPDIIHNHKKPITLPDLLSGLKLHSSKSNAIHRLMRLLVHAQFFDIIKLEENSETEGYVLTTSSRLLLKSEIPNLSPCVRLMVDPVFVTPWQLLEGWFHKNEEATPFETAHGMPMWDLCAQNPIFDRVFNEAMASDSQMMRLVVKDCREVFEGLSSLVDVGGGTGIVAKTILEAIPHLKCTVLDLPHVVANMPQTENLIYVGGNMFQCIPHADAILLKHVMHNWSDEDCVKILKRCREAIEDKDEGRKGKVLIIDMVLGRDEEEANMTEVKLIFDVLMMVVATGRQRTEKEWEKLFTEAGFMSYKITPLLGLRSLIQVFP
>rna-XM_015209873.2
MDVPMSSEMFEAQAHIYKHAFSFANSMVLGCAIQLGIPDVIHSHKQPMTLSQLVSELKLPLEKSEAIHRLMRLLVYSGFFATTDFLDENSESQQGYVLTPSSKLLLKSEIPNLSPFARAMIDPVMVNPWQSLGDWFLGNETTPFETAHGAPMWKFCDQNPRFNNVFNEAMASDSQMMCLVVNDCKQVFQEIDSLVDVGGGTGIIANTILAAFPHLKCTVLDLPHVVANMPDTHNVQYVGGDMFHSIPSADAILFKHVMHNWSDENCVKILKRCGEAIKDKNEGRKGKVLIIDMVLDRDKEEANMTEVKLIFDVLMMVLLTGRERTEKEWEKLFLEAGFMSYKITPLFGLRSLIEVFP
>rna-XM_027915458.1
MSCHLSNFSYKYRFHSPNITHLKEKMALSDNIGDETNEVLAAQAHIANHVFNYINSMSLKCAIQLGIPDIIHNHGRAMTQSDLVNALPINKSKGHDCIYRLMRILIHAGFFTQGEEGYLLTPTSRLLLKNGPLSLAPFVQAQLDPVLMDPWHSLGEWFANEDSTPFATAHGKPLFEYAGDDQRLNNLFNEAMGCDARLIMSVLIKNGKGVFEGLKSLVDVGGGIGTVAKAISNAFPELQCSVFDLPHVVEGLEGGKNLSYIGGDMFKFVPSADAVLLKWVLHDWSDENCVKILKKCKEAIPSKENGGKVIVIDIVIDNQKGDNKSFETQLFSDVLMMVHVSGKERNEQEWAKLFSDAGFSDYKISPILGLRSVIEVYP
>rna-XM_015222142.2
MANNNNICAYELIEAEAQSWDYILSYLRPSCIKCAIQLGIPDILHKNAHPIMSLSDLIAALPNLNPSKTTFIPILMRVLVDFGLFNYHHQQGDGYSLTSVGRLLVENHLSGSNRSFFLFAQHPVVLNTAASVGDWLKDDLRTAFETAHGKSHWDYCGEDAEFNGVFNDAMAGDSRFISNLLISDCCAGVFEGLTSLVDIGGGTGAVAMAIAGAFPSLKCIVLDLPHVIADRKGSGNLEFVAGSMFDKIPNANAILLKWILHNWNDEDCVKLLKKCKESISSKENGGKVIIIDMIMEDNCNNKQLVQSQHLMDLIMRITCASKERTEKEWEKLFLEAGFNGYKIITSLGIRSLIEIYP
>rna-XM_015222455.2
MANKNNMYANELIEAEAQSWDYILTYLRPPCVRCAIQLGIPDILHKNADPIMSLSDLIAALPNLNPSKTTFIPILMRVLVDLGLFNYHHQQGDGYSLTSVGRLFVENDPSNKRSIFTFLTQFEIVDSMSDWLRNDLPTAFETAHGKSIWDYCAGESEYSGVFNDAMASDSKLISNLLISDCCSGVFEGLTSLVDVGGGTGTVAMAIAGAFPSLKCAVLDLPHAIGDRKGTQNLEFVAGNMFDKIPHANAILLKWILHDWNDEDCVKILKKCKESIPSKEKGGKLIIIDIVMEDNCSNNERLVQSQHLMDLLVRIIYASKERSNKEWEKLFLDAGFSGYKIITSLGLRSLMEVYP
>rna-XM_015230944.2
MALPNNIGDETNEVLAAQAHILNHVLNYVISMSLKCAIQLEIPDIIYSHGRAMTLSDLLNALPINKLKGHKCIYRLMRILIHVDFFIQGEEGYLHTPTSRLLLKNEPLSLSPFVQAELDPILMDPWHSLTEWFMNGDSTTFATTHGKLLFEYAGDDPRVNRLLNEAMGSDARLIIRVLIKNGKGVFEGLKSLVDVGGGTRTVARAISNAFPELKCSVFDLPHVVEGLEGGNNLSYIGGDMFKSVPSAHAILLKWILHDWSDEDCVKILKKCKEAIPSKENGGKVIVIDIVIDNEKRDNKSFETQLFSDVLMMVHVSGKERNEQEWAKLFSDSGFSHYNISHILGLRSVIEVYP
>rna-XM_015233922.2
MADHNENLTPSELLQAETQSWNQLYFFIEHVALKCALQLDIPNVITKHDKPMTISKLMSSLPISPSKYPYFHRLTRILIHYGFLILQKHDDNNVDDDKGCYSLAPADCYVAKDGPWNSMEDQDTFFFKAWSCLGDWFKNDDPSAFYTAYGDLFWSKLSSDSSTGNWFNENMSRDSRSFMNVLIGNEYKDVFKGLTSLVDVGGGTGTVAMSIAKSFPDMKCIVLDLPPVVANLQGSENLEFVAGDMFQKIPPANAVLLKSILHDWNDEECVKILKNCKEALRGSGKVIIIDMVMENTELDDETVHAKLFIDMLMMVFVGSKERNKKEWEKLFLISGFTSYKIVLTLGLRSVIELYP
>rna-XM_015233317.2
MVVPIVGEHETEILHAQTHIWNHIFSFINSMSLKSAIQLNIPDIIHKHGKPMTLDELANALSINHSKITHLRRLMRILVHSGFFLKSGSGSGSESGSVEGGYVLAPPARLLLKDEPLTVTPFLLAMLDPILVKPWHNVSEWFTSDEPTAFEVAHGRTFWDYAGHEPRLNHFFNDAMASDAKLVMSVVMKYSKDVFEGLNSIVDVGGGTGTVAKTIAKTFPNLQCTVFDLPHVVEGLEGSDNLTYVGGDFFVSIPHAEALLLKWILHDWSDEESVKILKKCKEAIPSKEKGGKVIIIDMMVDNKIGDDESIETQIFFDMLMMVLVTGRERSEKGWAKIFFEAGFSDYKVTPILGLRSLIEVYP
>rna-XM_015204456.2
MTLPNDNMTREMLAAQAHIWNHTFSYVKSMSLKCAIQLGIPDIIHSHGRAMTLPDLVDALPINNNAKTLDYIFRLMRILIHGGFFNQIKVNDTEEGYLLTPASCLLLKDEPLSQVAFVQMELDPNFIDPWHSLSKWIRSDNDDSSTPFAIAHGKSLFEYDERQPNINRQFNEIMASDSRLLISVVIKNCRGVFEGLKSFVDVGGGIGIVAKVIADAFLDMNCIVFDLPHVIEGCEGSKNIIYVGGDMFKFIPYADAILLKWILHDWSDEKCIKILKKCKDAIPSKEKGGKVIIIDMVLMDHNLENVDDKSYETQLFFDMLMMVHVSGKERNQQDWAKLISGAGFSDYNIIPILGLRSIIDVFP
>rna-XM_015204394.2
MEKETNGKAKRNDEKIQESHEAQANMWKFVFGFTEMAVIKCAIELGIADFLEKNQEPISLNQLSIALGCCSTSLYRILRFLINRGIFKETSTKSGKNGYVQTPLSRLLIKEGENSMAAFLLFESSPVMLAPWHNLSARISSKDNSTPAFDAAHGKDIWKYAEADSGLSNLLNNAMACDAKVTVSAIIDSCPEIFEGVNTMVDVGGGDGTTLRLLVEAFPWINGINFDLPHVASVAPHAIGVVHVGGDMFNYVPKADAAFLMWVLHDWGDEECIQILTKCREAIPKDKGKVIILEAIIGEKEENNIIRGSNNEKLKDVGLMLDMVMMAHTSNGKERTSKEWAYVLNEAGFGRHTISHINAVQSVIQAYPS
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University