Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Sisymbrium irio
Species name
Sisymbrium irio is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Sisymbrium_irio.HIDH.fa
Download
>SI_scaffold28_27.mRNA1
MEATKTQVSLEVLPWLVVHSDGTLERLAGTEVCPPGLDPETGVLSKDIIIDPKTGLSARIYRPDSVQTGQKLPLVLYFHGGAFLIASASLPNYHTSVNKLVAQANIIAVSVDYRLAPEHPLPTAYEDSWNALRGIQATNEPWINEYADFDRFFLAGDSAGANISHHLSFRAKQSDQTVKIKGIGMIHPYFWGTQPIGSEGSEVTDVARKQMVDGWWRFVCPSEKGSDDPWINPFADGSPDLEGLGCEKVMVTVAEKDILSERGKMYYERLVKSKWRGKAEIMETKGKDHVFHIFEPDCDEAKEMVRCLALFINQDVEA
>SI_scaffold421_1.mRNA1
MDTEIAVDCSPLLKIYKSGRIERLMGETTVPASLTPQSGVVSKDVVYSPEHNLSVRIYLPEKASETGEKLPLLVYFHGGGFIIETAFSPTYHTFLTAAVSASNCVAVSVDYRRAPEHPIPVSYDDSWTSLKWVFTHIAGSGPESWLNKHADFSKVFLAGDSAGANIAHHMAVRAAEEKLSPDLSGSGVSGAILVHPYFWSKTSIDDKETKDV
>SI_scaffold421_4.mRNA1
MDSEIAVDYSPFLKMYKSGRIERLMGETTVPASLTPQSGVVSKDVVYSPADNLSVRIYLPDKAAETGEKLPLLVYFHGGGFILETAFSPTYHTFLTAAVSASDCVAVSVDYRRAPENPIPVPYDDSWTSLKWVFTHIAGSGQESWLNKHADFSKVFLAGDSAGANIVHHMAVRAAKEKLSPELNGSGISGAILVHPYFWSKTPIDDKETKDVTSRSKIEGLWTMASPNSKDGVDDPFINVVQSESVDLSGLGCGKVHVMVAEKDALVRQGWGYVAKLEKSGWKGKVELVESEGEDHVFHLTRPDCEKALEAMKILRRFLKEEM
>SI_scaffold689_41.mRNA1
MESEIASEFLPFGRIYKDGRVERLTGTEIIPTSLDTANDVVSKDVLYSPEHNLSVRIFLPHKSTQLSTAGGNKLPLLIYIHGGAWIIESPFSPIYHNYLTQVVKSSNCLGVSIQYRRAPEHPIPAAYEDTWSAIQWVFSHLHGSGPEEWINKHADFSRVFIGGDSAGANMTHHMAMRAGKEKLGPKIKGIAVVHPAFWGTDPVDEEDVQDKDMRSGIAEVWEKIASPNSVKGTDDPLFNVVGSDSDLSGLGCEKVLVAVAGKDVFVRQGLGYAAKVKKSGWKGDVEVVVDDEEGHVFHLQNPSCENASNFLKKFVKFITG
>SI_scaffold689_42.mRNA1
MQMLRRIAISSSRPHVFRFLCHSPRLYLSPSFSKTAVIVSRHRLTTLRCICSHSSSDLLSEHPPFVKIYKDGHVERLSGTETVPASLTPQNGVVSKDVVYSQEHNLSVRLFLPHKATELAACNNKLPLLIYIHGGAWIIESPFSPNYHNFLTEVVKSAGCLAVSIQYRRAPEHPIPAAFEDAWSAIQWVFSHADGTGPEEWINRYADFNRVFLAGDSAGANMSHHMAMRAGKEKLKPRIKGTAIVHPAFWGKDPIDEQDLQDREARSRVAEVWEKLASPNSVDGVDDPLFNVVGSESEFSELGCEKVLVAVAGKDVFVRQGLGYAAKLKKSGWKGDVEVMEEEDEDHCFHLLNPSSENAPTFMKKFVQFISG
>SI_scaffold689_43.mRNA1
MESHLTSNHLPSIRIHKNGRVERLRGNDVVSASLDPQNDVISKDVMYSPEHNLSVRLFLPHKSTQLVSSEKLPLLIYFHGGAYIMESPFSPVYNNYLTEVVKTSNCLAVSVQYRRAPEHPVPAAYDDAWSAVQWTFTHSDGFGEDVWINEFADFDRVFVAGDSAGANISHHMVMRAGKEKLNPRIKGVAMVHPGFWGKDPVDEKDVQDERTRSQVAEIWEKIVSPNSVDGVDDPWINVVGSGSDISGLGCERVLVAVAGKDVFGRQGLAYAAKLKKSGWEGDLEVVEEEEEGHCFHLRNPNSENALKLMKAFVAFIIASSVENEIMILRTMSTILDSPGGFIYHCVDFMPLNLYTSKTLVSLKLSSSGLEDPGFVSMPKHLVGIQWHELTLLRDNDGEVAVMRLRSRSLKRLCSVEYKTFCKSNVEYTLEIDAPGLEYMSVKEDHFDRYVVKNHLNSLFKIDLDIKFVVKFDMFLDPEDLSKSNEIRDFLIGISSVRHLVMSTCRGKKNGGPVRAGLLGHNGPGRHRPVILPPSKAGGGRCSVKPASRNLLRSKRGRTTSFRPSPNPQLPTWNGQASKQPRTEPGPIEQPIIPPFYSLHSDYKPKLLSSTRINREYMILIAENFVLCIWCQSNGFVMLLSYDMFVDASKYKRVMKIHKAFDGFAYANDSQVALKKEQLCTKIQFLESEYESIPCISGFFLWLLNLLRQEQFLSL
>SI_scaffold843_226.mRNA1
MAAISFTHNHQSSGNRRGGSHHHRHGPVVEEIEGLIKVFNDGCVERPPIVPTVSPTVHPSAKVTAFDIKLSSDTSARVYIPDAAAFSPSVTLPLLVYFHGGGFCVGSAAWSCYHDFLTDLAVKARCIVVSVNYRLAPEHRLPAAYDDGVNVVSWLMKQGSNGGYSWVSKCNLSNVFLAGDSAGANIAYQVAVRITGGGKSVHTSNLKGVILIHPFFGGEPRTSSEKQQHSKSSALTLSASDTYWRLALPRGASRDHPWCNPLVSSSAGSFREARLPTTMVFMAEFDILIDRNLEMCKVMRSHGKRVEGIVHGGVGHAFHILDNSSVSRDRIHDMVCRLHNFMHP
>SI_scaffold1468_55.mRNA1
MVSDSEIAYDYPRYRVYKNGRIERLVTKTFVPPSLNPENGVVSKDAVYSPEKNLSLRIYLPHKAVLEKKEKLTLLVYFHGGGWFNEKANFSRVFIAGDSAGANIAHHMGIRAGKENGSLKVLEMTLFHPFFFSKAPVEEHEAEAMRYMQGVWEIASPNCEMGVEDPWVNVVGSDISGLGCGRVLVMVAGNDVLAREGWGYAAKLEKSSGWEGRVGVIETKDEGHIFHIKNPNSDSARLVVHRFVEFLKDETSW
>SI_scaffold1659_23.mRNA1
MGATPLADVTTFNPNNTNIHGPVVEEVEGLIRVYKDGHVERSQLLPCVGPSASLPLEFGVSCSDVHIDKLTNVWARLYVPMATKSSSVSKLPIIVYFHGGGFCIGSASWACYHQFLARLSANSRCLVMSVNYRLAPENPLPAAYEDGINAILWLKKTRNDNLWSKLCDFGNIFLAGDSAGGNIAHHVAARLAAADALIKPLKIEGTILIQPFFGGEARTESERRVGNNMKSSVLTLASSDTWWRLALPRDANREHPYCKPVTFKTRTLVCVAEMDVLMDREMEICDSNEKMIKRVVYKGVGHAFQILDKSQLAHTMTLEMLCHIDAFLHH
>SI_scaffold1808_30.mRNA1
MFIIYKSGRLERLVGETTVPPSLTPQNGVISKKAANLSVRIYLPEKAAKSGEKLPLLVYFHGGGFVVETPFSPTYHTFLTDAVSASYCVAVSVDYRRAPEHPIPISHDDSWTSLQWVFTHMAGRGPESWLNKHADFSKVFVAGDSAGANITHHMTMRAAKEKLSPDLSGSGISGIILVDPYFWSKTPVDDKETTDVTERSRAEDLWKITSPNSKDGVDDPFLNVVQSKAVDISGLGCGKVLVMVAELDTLVRQGLGYASKLERSGWKGKVELMHGD
>SI_scaffold2549_1.mRNA1
MDSDIAFDNSPGYRVYKNGRIERLMGETFTPPSLTPQKGVVSKDTVYSTEKNLAVRIHLPEEASVTGEKLPVLVYFHGGGFIIETAFSPNYNTFLTSVVAAANCMAISVDYRRAPEFPIPAPYEDSWDSLKWVLSHVDGAGPEQWINKHGDFKKVFLAGDSAGANISHHLAIRTKREKLDSLSGIILIHPYFWGKLPLDELETRDENVRKRVERSWGVASPNSENGVDDPLFNVVGSESSDLSGLGCGRVLVVVAGDDKFVRQGFGYAAKLEESGWEGEVELMEIKDEGHVHHLKNPNTDNARKVVNKVAEYVNK
>SI_C149543_1.mRNA1
MASPNSKDGADDPFLNVVQSDSVDLSGLGCGKVLVMVAEKDALARQ
>SI_C178383_1.mRNA1
MVAEKDALARQGWGYVAKLEKSGWKGKVELVESEGEDHVFHLMRPDCEKALEAMKIFASFLKGEM
>SI_C182029_2.mRNA1
MASPNSKEGADDPVFNVVQSESVDISGLGCGKVLVMVAEKDALARQGWGYVAKLEKSGWKGKVELVESVGEDHVFHLMRPDCEKALEAMKKFAGFLKGEM
MEATKTQVSLEVLPWLVVHSDGTLERLAGTEVCPPGLDPETGVLSKDIIIDPKTGLSARIYRPDSVQTGQKLPLVLYFHGGAFLIASASLPNYHTSVNKLVAQANIIAVSVDYRLAPEHPLPTAYEDSWNALRGIQATNEPWINEYADFDRFFLAGDSAGANISHHLSFRAKQSDQTVKIKGIGMIHPYFWGTQPIGSEGSEVTDVARKQMVDGWWRFVCPSEKGSDDPWINPFADGSPDLEGLGCEKVMVTVAEKDILSERGKMYYERLVKSKWRGKAEIMETKGKDHVFHIFEPDCDEAKEMVRCLALFINQDVEA
>SI_scaffold421_1.mRNA1
MDTEIAVDCSPLLKIYKSGRIERLMGETTVPASLTPQSGVVSKDVVYSPEHNLSVRIYLPEKASETGEKLPLLVYFHGGGFIIETAFSPTYHTFLTAAVSASNCVAVSVDYRRAPEHPIPVSYDDSWTSLKWVFTHIAGSGPESWLNKHADFSKVFLAGDSAGANIAHHMAVRAAEEKLSPDLSGSGVSGAILVHPYFWSKTSIDDKETKDV
>SI_scaffold421_4.mRNA1
MDSEIAVDYSPFLKMYKSGRIERLMGETTVPASLTPQSGVVSKDVVYSPADNLSVRIYLPDKAAETGEKLPLLVYFHGGGFILETAFSPTYHTFLTAAVSASDCVAVSVDYRRAPENPIPVPYDDSWTSLKWVFTHIAGSGQESWLNKHADFSKVFLAGDSAGANIVHHMAVRAAKEKLSPELNGSGISGAILVHPYFWSKTPIDDKETKDVTSRSKIEGLWTMASPNSKDGVDDPFINVVQSESVDLSGLGCGKVHVMVAEKDALVRQGWGYVAKLEKSGWKGKVELVESEGEDHVFHLTRPDCEKALEAMKILRRFLKEEM
>SI_scaffold689_41.mRNA1
MESEIASEFLPFGRIYKDGRVERLTGTEIIPTSLDTANDVVSKDVLYSPEHNLSVRIFLPHKSTQLSTAGGNKLPLLIYIHGGAWIIESPFSPIYHNYLTQVVKSSNCLGVSIQYRRAPEHPIPAAYEDTWSAIQWVFSHLHGSGPEEWINKHADFSRVFIGGDSAGANMTHHMAMRAGKEKLGPKIKGIAVVHPAFWGTDPVDEEDVQDKDMRSGIAEVWEKIASPNSVKGTDDPLFNVVGSDSDLSGLGCEKVLVAVAGKDVFVRQGLGYAAKVKKSGWKGDVEVVVDDEEGHVFHLQNPSCENASNFLKKFVKFITG
>SI_scaffold689_42.mRNA1
MQMLRRIAISSSRPHVFRFLCHSPRLYLSPSFSKTAVIVSRHRLTTLRCICSHSSSDLLSEHPPFVKIYKDGHVERLSGTETVPASLTPQNGVVSKDVVYSQEHNLSVRLFLPHKATELAACNNKLPLLIYIHGGAWIIESPFSPNYHNFLTEVVKSAGCLAVSIQYRRAPEHPIPAAFEDAWSAIQWVFSHADGTGPEEWINRYADFNRVFLAGDSAGANMSHHMAMRAGKEKLKPRIKGTAIVHPAFWGKDPIDEQDLQDREARSRVAEVWEKLASPNSVDGVDDPLFNVVGSESEFSELGCEKVLVAVAGKDVFVRQGLGYAAKLKKSGWKGDVEVMEEEDEDHCFHLLNPSSENAPTFMKKFVQFISG
>SI_scaffold689_43.mRNA1
MESHLTSNHLPSIRIHKNGRVERLRGNDVVSASLDPQNDVISKDVMYSPEHNLSVRLFLPHKSTQLVSSEKLPLLIYFHGGAYIMESPFSPVYNNYLTEVVKTSNCLAVSVQYRRAPEHPVPAAYDDAWSAVQWTFTHSDGFGEDVWINEFADFDRVFVAGDSAGANISHHMVMRAGKEKLNPRIKGVAMVHPGFWGKDPVDEKDVQDERTRSQVAEIWEKIVSPNSVDGVDDPWINVVGSGSDISGLGCERVLVAVAGKDVFGRQGLAYAAKLKKSGWEGDLEVVEEEEEGHCFHLRNPNSENALKLMKAFVAFIIASSVENEIMILRTMSTILDSPGGFIYHCVDFMPLNLYTSKTLVSLKLSSSGLEDPGFVSMPKHLVGIQWHELTLLRDNDGEVAVMRLRSRSLKRLCSVEYKTFCKSNVEYTLEIDAPGLEYMSVKEDHFDRYVVKNHLNSLFKIDLDIKFVVKFDMFLDPEDLSKSNEIRDFLIGISSVRHLVMSTCRGKKNGGPVRAGLLGHNGPGRHRPVILPPSKAGGGRCSVKPASRNLLRSKRGRTTSFRPSPNPQLPTWNGQASKQPRTEPGPIEQPIIPPFYSLHSDYKPKLLSSTRINREYMILIAENFVLCIWCQSNGFVMLLSYDMFVDASKYKRVMKIHKAFDGFAYANDSQVALKKEQLCTKIQFLESEYESIPCISGFFLWLLNLLRQEQFLSL
>SI_scaffold843_226.mRNA1
MAAISFTHNHQSSGNRRGGSHHHRHGPVVEEIEGLIKVFNDGCVERPPIVPTVSPTVHPSAKVTAFDIKLSSDTSARVYIPDAAAFSPSVTLPLLVYFHGGGFCVGSAAWSCYHDFLTDLAVKARCIVVSVNYRLAPEHRLPAAYDDGVNVVSWLMKQGSNGGYSWVSKCNLSNVFLAGDSAGANIAYQVAVRITGGGKSVHTSNLKGVILIHPFFGGEPRTSSEKQQHSKSSALTLSASDTYWRLALPRGASRDHPWCNPLVSSSAGSFREARLPTTMVFMAEFDILIDRNLEMCKVMRSHGKRVEGIVHGGVGHAFHILDNSSVSRDRIHDMVCRLHNFMHP
>SI_scaffold1468_55.mRNA1
MVSDSEIAYDYPRYRVYKNGRIERLVTKTFVPPSLNPENGVVSKDAVYSPEKNLSLRIYLPHKAVLEKKEKLTLLVYFHGGGWFNEKANFSRVFIAGDSAGANIAHHMGIRAGKENGSLKVLEMTLFHPFFFSKAPVEEHEAEAMRYMQGVWEIASPNCEMGVEDPWVNVVGSDISGLGCGRVLVMVAGNDVLAREGWGYAAKLEKSSGWEGRVGVIETKDEGHIFHIKNPNSDSARLVVHRFVEFLKDETSW
>SI_scaffold1659_23.mRNA1
MGATPLADVTTFNPNNTNIHGPVVEEVEGLIRVYKDGHVERSQLLPCVGPSASLPLEFGVSCSDVHIDKLTNVWARLYVPMATKSSSVSKLPIIVYFHGGGFCIGSASWACYHQFLARLSANSRCLVMSVNYRLAPENPLPAAYEDGINAILWLKKTRNDNLWSKLCDFGNIFLAGDSAGGNIAHHVAARLAAADALIKPLKIEGTILIQPFFGGEARTESERRVGNNMKSSVLTLASSDTWWRLALPRDANREHPYCKPVTFKTRTLVCVAEMDVLMDREMEICDSNEKMIKRVVYKGVGHAFQILDKSQLAHTMTLEMLCHIDAFLHH
>SI_scaffold1808_30.mRNA1
MFIIYKSGRLERLVGETTVPPSLTPQNGVISKKAANLSVRIYLPEKAAKSGEKLPLLVYFHGGGFVVETPFSPTYHTFLTDAVSASYCVAVSVDYRRAPEHPIPISHDDSWTSLQWVFTHMAGRGPESWLNKHADFSKVFVAGDSAGANITHHMTMRAAKEKLSPDLSGSGISGIILVDPYFWSKTPVDDKETTDVTERSRAEDLWKITSPNSKDGVDDPFLNVVQSKAVDISGLGCGKVLVMVAELDTLVRQGLGYASKLERSGWKGKVELMHGD
>SI_scaffold2549_1.mRNA1
MDSDIAFDNSPGYRVYKNGRIERLMGETFTPPSLTPQKGVVSKDTVYSTEKNLAVRIHLPEEASVTGEKLPVLVYFHGGGFIIETAFSPNYNTFLTSVVAAANCMAISVDYRRAPEFPIPAPYEDSWDSLKWVLSHVDGAGPEQWINKHGDFKKVFLAGDSAGANISHHLAIRTKREKLDSLSGIILIHPYFWGKLPLDELETRDENVRKRVERSWGVASPNSENGVDDPLFNVVGSESSDLSGLGCGRVLVVVAGDDKFVRQGFGYAAKLEESGWEGEVELMEIKDEGHVHHLKNPNTDNARKVVNKVAEYVNK
>SI_C149543_1.mRNA1
MASPNSKDGADDPFLNVVQSDSVDLSGLGCGKVLVMVAEKDALARQ
>SI_C178383_1.mRNA1
MVAEKDALARQGWGYVAKLEKSGWKGKVELVESEGEDHVFHLMRPDCEKALEAMKIFASFLKGEM
>SI_C182029_2.mRNA1
MASPNSKEGADDPVFNVVQSESVDISGLGCGKVLVMVAEKDALARQGWGYVAKLEKSGWKGKVELVESVGEDHVFHLMRPDCEKALEAMKKFAGFLKGEM
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University