Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Simmondsia chinensis
Species name
Goatnut (Simmondsia chinensis) is a species of eudicot in the family Simmondsiaceae.
Species info
Gene sequence info
Simmondsia_chinensis.CHS.fa
Download
>Sc03g0005300.01
MATSVQEIRESQRASGPATILAIGTANPPNVMYQADYPDFYFRITKSEHMAELKEKFKRMCDKSMINKRYMYLNEEILKENQNMCEYMGSSLDTRQDMVVVEVPRLGKEAAARAIKEWGQPKSKITHVIFCTTSGVDMPGADYQLTKLLGLRPSVRRFMLYQQGCFAGGTVLRLAKDLAENNMGARVLVVCSEITAICFRGPTETHLDSMVGQALFGDGAAAVIVGADPDLSIERPIFQLVWTAQTLLPDSEGAIDGHLRQVGLTFHLLKDVPGLISKNINKALVEAFNPIGINDWNSIFWVAHPGGPAILDQVEAKLGLKEEKLKATRNVLNDYGNMSSACVLFILDEMRKKSMEEGKATTGEGLNWGVLFGFGPGLTVETVVLHSVPLNN
>Sc03g0005290.01
MAAVTVEEIRKAQRANGPAAILAIGTANPPNVVYQADYPDFYFRITNSEHMTDLKEKFKRMCDKSMIKKRYMHLTEDILKDNPEMCEYMGSSLDSRQDMVVVEVPKLGKEAASRAIKEWGQPKSKISHVIFCTTSGVDMPGADYQLTKLLGLRPSVRRFMLYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAICFRGPTETHLDSMVGQALFGDGAAAVIVGADPDESIERPIFQLVWTGQTLLPDSEGAIDGHLRQVGLTFHLLKDVPGLISKNIDKALVEAFNPLGINDWNSIFWVAHPGGPAILDQVEAKLGLKEEKLKATRNVLNDYGNMSSACVLFILDEMRKKSMEDGKATTGEGLDWGVLFGFGPGLTVETVVLHSVPIRF
>Sc07g0003850.01
MAAPSSIQVEDIIKAQKADGPATILAIGTANPPNVFYQADYPEFYFRVTNSEHMTDLKQKFKRMCERSMIKKRYMYLTEDILKENPNMLTYNTPSFDTRQNMVIVEVPKLAKEAASRAIKEWGQPRSKITHVIFCTTSGMDMPGADFQLTKLLGLRPSVRRFMLYQQGCFAGGTVLRLAKDIAENNRGARVLVVCSEITAICFCGPTETHLDAMVGQALFGDGAGAVIVGSDPDPTEKPIFQLVWAGQTILPDSEGAIDGHVKEVGLTFHLLKDVPGLISKNIEKSLIEAFGPIGLSDWNNIFWAAHPGGPAILDQVEARLGLKEERLEATRNVLREYGNMSSACVLFILDELRKKSMEEGKATTGEGLEWGVLFGFGPGLTVETVILHSVPLVN
>Sc07g0003870.01
MAAPSPVQVEDIIKAQKADGPATILAIGTANPPNVFYQDDYADFYFRVTNSEHMTDLKQKFKRMCERSMIKKRYMYLTEEILKENPNLLTYNTPSLDTRQDMVIVEVPKLAKEAASRAIKEWGQPRSKITHVIFCTTSGLDMPGADFQLTKLLGLRPSVRRFMLYQQGCFAGGTVLRLAKDIAENNRGARVLVVCSEITAICFCGPTETRLDAMVGQALFGDGAGAVIVGSDPDPTEKPIFQLVWAGQTILPDSEGAIDGHVKEVGLTFHLLKDVPGLISKNIEKSLIEAFGPIGLSDWNSIFWAAHPGGPTILDHVEAKLGLKEDKLKATRNVLSEYGNMSSACVLFILDELRKKSVEEGKATTGEGLEWGVLFGFGPGLTVETVVLHSVPLVN
>Sc07g0003860.01
MAVPSSVQVEDILKAQKADGPATILAIGTANPPNVFYQADYPDFYFRVTNSEHMTDLKHKFKRMCERSMIKKRYMYLTEDILKENPNMLTYSTPSFDTRQDMVIVEVPKLAKEAASRAIKEWGQPRSKITHVIFCTTSGMDMPGADFQLTKLLGLRPSVRRFMLYQQGCFAGGTVLRLAKDIAENNRGARVLVVCSEITAICFCGPTETRLDAMVGQALFGDGAGAVIVGSDPDPTEKPIFQLVWAGQTILPDSEGAIDGHVKEVGLTFHLLKDVPGLISKNIEKSLIEAFGPIGLSDWNNIFWAAHPGGPAILDQVEARLGLKEERLEATRNVLREYGNMSSACVLFILDELRKKSMEEGKATTGEGLEWGVLFGFGPGLTVETVVLHSVPLVN
>Sc10g0005260.01
MDHDQKMRQAQRAEGPAMILAIGTANPTNCVRQDDFPDFYFRVTNSEHMTKLKDKFKRICERTTIKQRYLLNITEETLKENPNICTHMAPSLDARQGMVVMEIPKLGEQAALKALKEWGQPKSMITHLVFVTTSGVDVPGADYHLTKILGLSSSVNRHMVYLQGCFAGATALRLAKDLAENNRSARVLVVCSEIITIGFRGPNEDHLDTLVAQALFGDGAAAAVVGADPDEPTERPLFRLVSAGQTILPDSEEVMALHIKEVGLTATMTQDVPTVIAANLESCLAQAFNPIIGDIPIGGWNSIFWVAHPGGPAILDQVETKLGLSTKKLSISRHVLSEYGNMMSCTVLFILDEMRKTSLKEGKATTGEGFEWGILLGFGPGITVETIVLQSVPLRSNNSG
>Sc10g0005250.01
MAPSLDTSQDMVTRDIPKLREKVALMAFKEWGHPKSVITHLVFVTTSRVDVPGADYHLVKLLGLSPSINRHMVSL
>Sc11g0005910.01
MERVYEIREAKKANGVAAVLAIGRANPTNFIHQADYPDYYFRVTNSEHMADLKEKFKRICDKTMIRKRHFFLTEEILKENPSMLTYGMSSADARREMALKYLPELGKEAALKAIKEWGQPKSRITHLFVYNTLSLSMPGADYDLAKALDLPTSVHRTAMYLVGCHAGPHILRHAKDIAENNHGARILVVCAETTAVNFHGPSSTQVDSLVGQALFGDGAAAVIVGADPDISIERPIFHLVYGMQLTIPDTSGAAYSEIIQMGQTFHLRRDLPCLISKYIRESLVKVFEPIGINDWNSIFWIAHNGGPAVLNDIESELGLEKDKLSVARYVLSEYGNMSSIGVLFMMDEMRKRSLEEGKTTTGLGLEWGVMFGFGPGLTVEALALHSVPSLE
>Sc11g0005920.01
MSRNDCEILTRVWKGSIIKGDKGVRPTQVEDHPPLSLQHLGLVYAWCRLQLSQGPDLSIERPVLHLVYGMPLTIPDTSRAAFLEIIQMGQTFRLQRDLPCLTSKNIRESLVKVFEPVIGTPSSG
>Sc16g0005770.01
MATSVEEIRSSQRAYGLATILAIGTATPPNVMYQANYPDFYFRITKSEHMTDLKEKFKRMCDKSMINKRYMYLNEEILKENPNMCECMGSSIDTRQDMVVVEVPRLGKEAAARAIKEWGQPKSKITHLIVCTTSGVDMPGADYRLTKLLGLSPSVRRFMFYQLGCYAGGTVLRLAKDLAENNKGARILIVCSEVTAVCFHGPTETHLDSMVGQALFGDGAGAVIVGADPDLSVERPIFQLVRTAQTIVPDSEGAIEGRLREVGLVLHLLKDVPALISKNINKALEEAFNPIGINDWNSIFWVAHPGGTKILDQVEAKLGLKEEKLKESRNVLYDYGNMTSACVLFILDEMRKKSIQDGKATTGEGLEWGVLFGFGPGLTIETVVLHSVPLNNLGGAANSQIKNI
>Sc16g0005760.01
MATSINEICKAQWADGPATILAIGTTNPPNLMYQANYPNFCFRITKSEHMTDLKKKFKRIYLAKNNKGARVLVVCSKITVICFCGPSETHLDSTVTQALFGVGAGAIIVGEDPDFSVE
>Sc18g0006710.01
MRIDELARESMRKKASPGKATVLALGKAFPHQLVMQEFLVDGYFKNTNCDDPDLKEKLTRLCKTTTVKTRYVVMSEEILKKYPELALEGRPTVTQRLDICNKAVTQMAIEASNACITNWGRPASDITHLVYVSSSEARLPGGDLHLAKGLGLKPNTSRVMLYFSGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSAERPYDLVGVALFGDGAGAMIIGSDPFYNIERPTFELHTAIQHFLPDTEKIIDGKLTEEGISFKLDRALPQIIEDNIEEFCVKLMKNASFSEKDYNNLFWAVHPGGPAILNRVEKKLNLKPRKLSASRRALEDYGNASSNTIVYVMEYVMEESLKVKEEEEEENEWGLILAFGPGVTFEGVLARNLTI
>Sc26g0001400.01
MSNYNGNGVNGNQSVRTQLAPTPGKATVLAMGKAFPKQLIPQECLVEGYIRDTKCNDLAIKEKLERLCKTTTVKTRYTVMSKEILDNYPELATEGSTTIKQRLEIANPAVVEMALEASLACIKEWGRSVQDITHIVYVSSSEIRLPGGDLYLASKLGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLVTTSETTILGFRPPNKARPYDLVGAALFGDGAAAAIIGTDPILGKESPFMELNHAIQQFLPGTNDVIDGRLTEEGINFKLGRDLPNKIEDNIEEFCKKLMSKTGVTLDFNDLFWAVHPGGPAILNRVESKLGLRPEKLECSRRALMDYGNVSSNTIFYVMENMREDLKKNKGEEWGLALAFGPGITFEGILMRSLS
MATSVQEIRESQRASGPATILAIGTANPPNVMYQADYPDFYFRITKSEHMAELKEKFKRMCDKSMINKRYMYLNEEILKENQNMCEYMGSSLDTRQDMVVVEVPRLGKEAAARAIKEWGQPKSKITHVIFCTTSGVDMPGADYQLTKLLGLRPSVRRFMLYQQGCFAGGTVLRLAKDLAENNMGARVLVVCSEITAICFRGPTETHLDSMVGQALFGDGAAAVIVGADPDLSIERPIFQLVWTAQTLLPDSEGAIDGHLRQVGLTFHLLKDVPGLISKNINKALVEAFNPIGINDWNSIFWVAHPGGPAILDQVEAKLGLKEEKLKATRNVLNDYGNMSSACVLFILDEMRKKSMEEGKATTGEGLNWGVLFGFGPGLTVETVVLHSVPLNN
>Sc03g0005290.01
MAAVTVEEIRKAQRANGPAAILAIGTANPPNVVYQADYPDFYFRITNSEHMTDLKEKFKRMCDKSMIKKRYMHLTEDILKDNPEMCEYMGSSLDSRQDMVVVEVPKLGKEAASRAIKEWGQPKSKISHVIFCTTSGVDMPGADYQLTKLLGLRPSVRRFMLYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAICFRGPTETHLDSMVGQALFGDGAAAVIVGADPDESIERPIFQLVWTGQTLLPDSEGAIDGHLRQVGLTFHLLKDVPGLISKNIDKALVEAFNPLGINDWNSIFWVAHPGGPAILDQVEAKLGLKEEKLKATRNVLNDYGNMSSACVLFILDEMRKKSMEDGKATTGEGLDWGVLFGFGPGLTVETVVLHSVPIRF
>Sc07g0003850.01
MAAPSSIQVEDIIKAQKADGPATILAIGTANPPNVFYQADYPEFYFRVTNSEHMTDLKQKFKRMCERSMIKKRYMYLTEDILKENPNMLTYNTPSFDTRQNMVIVEVPKLAKEAASRAIKEWGQPRSKITHVIFCTTSGMDMPGADFQLTKLLGLRPSVRRFMLYQQGCFAGGTVLRLAKDIAENNRGARVLVVCSEITAICFCGPTETHLDAMVGQALFGDGAGAVIVGSDPDPTEKPIFQLVWAGQTILPDSEGAIDGHVKEVGLTFHLLKDVPGLISKNIEKSLIEAFGPIGLSDWNNIFWAAHPGGPAILDQVEARLGLKEERLEATRNVLREYGNMSSACVLFILDELRKKSMEEGKATTGEGLEWGVLFGFGPGLTVETVILHSVPLVN
>Sc07g0003870.01
MAAPSPVQVEDIIKAQKADGPATILAIGTANPPNVFYQDDYADFYFRVTNSEHMTDLKQKFKRMCERSMIKKRYMYLTEEILKENPNLLTYNTPSLDTRQDMVIVEVPKLAKEAASRAIKEWGQPRSKITHVIFCTTSGLDMPGADFQLTKLLGLRPSVRRFMLYQQGCFAGGTVLRLAKDIAENNRGARVLVVCSEITAICFCGPTETRLDAMVGQALFGDGAGAVIVGSDPDPTEKPIFQLVWAGQTILPDSEGAIDGHVKEVGLTFHLLKDVPGLISKNIEKSLIEAFGPIGLSDWNSIFWAAHPGGPTILDHVEAKLGLKEDKLKATRNVLSEYGNMSSACVLFILDELRKKSVEEGKATTGEGLEWGVLFGFGPGLTVETVVLHSVPLVN
>Sc07g0003860.01
MAVPSSVQVEDILKAQKADGPATILAIGTANPPNVFYQADYPDFYFRVTNSEHMTDLKHKFKRMCERSMIKKRYMYLTEDILKENPNMLTYSTPSFDTRQDMVIVEVPKLAKEAASRAIKEWGQPRSKITHVIFCTTSGMDMPGADFQLTKLLGLRPSVRRFMLYQQGCFAGGTVLRLAKDIAENNRGARVLVVCSEITAICFCGPTETRLDAMVGQALFGDGAGAVIVGSDPDPTEKPIFQLVWAGQTILPDSEGAIDGHVKEVGLTFHLLKDVPGLISKNIEKSLIEAFGPIGLSDWNNIFWAAHPGGPAILDQVEARLGLKEERLEATRNVLREYGNMSSACVLFILDELRKKSMEEGKATTGEGLEWGVLFGFGPGLTVETVVLHSVPLVN
>Sc10g0005260.01
MDHDQKMRQAQRAEGPAMILAIGTANPTNCVRQDDFPDFYFRVTNSEHMTKLKDKFKRICERTTIKQRYLLNITEETLKENPNICTHMAPSLDARQGMVVMEIPKLGEQAALKALKEWGQPKSMITHLVFVTTSGVDVPGADYHLTKILGLSSSVNRHMVYLQGCFAGATALRLAKDLAENNRSARVLVVCSEIITIGFRGPNEDHLDTLVAQALFGDGAAAAVVGADPDEPTERPLFRLVSAGQTILPDSEEVMALHIKEVGLTATMTQDVPTVIAANLESCLAQAFNPIIGDIPIGGWNSIFWVAHPGGPAILDQVETKLGLSTKKLSISRHVLSEYGNMMSCTVLFILDEMRKTSLKEGKATTGEGFEWGILLGFGPGITVETIVLQSVPLRSNNSG
>Sc10g0005250.01
MAPSLDTSQDMVTRDIPKLREKVALMAFKEWGHPKSVITHLVFVTTSRVDVPGADYHLVKLLGLSPSINRHMVSL
>Sc11g0005910.01
MERVYEIREAKKANGVAAVLAIGRANPTNFIHQADYPDYYFRVTNSEHMADLKEKFKRICDKTMIRKRHFFLTEEILKENPSMLTYGMSSADARREMALKYLPELGKEAALKAIKEWGQPKSRITHLFVYNTLSLSMPGADYDLAKALDLPTSVHRTAMYLVGCHAGPHILRHAKDIAENNHGARILVVCAETTAVNFHGPSSTQVDSLVGQALFGDGAAAVIVGADPDISIERPIFHLVYGMQLTIPDTSGAAYSEIIQMGQTFHLRRDLPCLISKYIRESLVKVFEPIGINDWNSIFWIAHNGGPAVLNDIESELGLEKDKLSVARYVLSEYGNMSSIGVLFMMDEMRKRSLEEGKTTTGLGLEWGVMFGFGPGLTVEALALHSVPSLE
>Sc11g0005920.01
MSRNDCEILTRVWKGSIIKGDKGVRPTQVEDHPPLSLQHLGLVYAWCRLQLSQGPDLSIERPVLHLVYGMPLTIPDTSRAAFLEIIQMGQTFRLQRDLPCLTSKNIRESLVKVFEPVIGTPSSG
>Sc16g0005770.01
MATSVEEIRSSQRAYGLATILAIGTATPPNVMYQANYPDFYFRITKSEHMTDLKEKFKRMCDKSMINKRYMYLNEEILKENPNMCECMGSSIDTRQDMVVVEVPRLGKEAAARAIKEWGQPKSKITHLIVCTTSGVDMPGADYRLTKLLGLSPSVRRFMFYQLGCYAGGTVLRLAKDLAENNKGARILIVCSEVTAVCFHGPTETHLDSMVGQALFGDGAGAVIVGADPDLSVERPIFQLVRTAQTIVPDSEGAIEGRLREVGLVLHLLKDVPALISKNINKALEEAFNPIGINDWNSIFWVAHPGGTKILDQVEAKLGLKEEKLKESRNVLYDYGNMTSACVLFILDEMRKKSIQDGKATTGEGLEWGVLFGFGPGLTIETVVLHSVPLNNLGGAANSQIKNI
>Sc16g0005760.01
MATSINEICKAQWADGPATILAIGTTNPPNLMYQANYPNFCFRITKSEHMTDLKKKFKRIYLAKNNKGARVLVVCSKITVICFCGPSETHLDSTVTQALFGVGAGAIIVGEDPDFSVE
>Sc18g0006710.01
MRIDELARESMRKKASPGKATVLALGKAFPHQLVMQEFLVDGYFKNTNCDDPDLKEKLTRLCKTTTVKTRYVVMSEEILKKYPELALEGRPTVTQRLDICNKAVTQMAIEASNACITNWGRPASDITHLVYVSSSEARLPGGDLHLAKGLGLKPNTSRVMLYFSGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSAERPYDLVGVALFGDGAGAMIIGSDPFYNIERPTFELHTAIQHFLPDTEKIIDGKLTEEGISFKLDRALPQIIEDNIEEFCVKLMKNASFSEKDYNNLFWAVHPGGPAILNRVEKKLNLKPRKLSASRRALEDYGNASSNTIVYVMEYVMEESLKVKEEEEEENEWGLILAFGPGVTFEGVLARNLTI
>Sc26g0001400.01
MSNYNGNGVNGNQSVRTQLAPTPGKATVLAMGKAFPKQLIPQECLVEGYIRDTKCNDLAIKEKLERLCKTTTVKTRYTVMSKEILDNYPELATEGSTTIKQRLEIANPAVVEMALEASLACIKEWGRSVQDITHIVYVSSSEIRLPGGDLYLASKLGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLVTTSETTILGFRPPNKARPYDLVGAALFGDGAAAAIIGTDPILGKESPFMELNHAIQQFLPGTNDVIDGRLTEEGINFKLGRDLPNKIEDNIEEFCKKLMSKTGVTLDFNDLFWAVHPGGPAILNRVESKLGLRPEKLECSRRALMDYGNVSSNTIFYVMENMREDLKKNKGEEWGLALAFGPGITFEGILMRSLS
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University