Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Setaria italica
Species name
Foxtail millet (Setaria italica) is a species of monocot in the family Poaceae (grass family).
Species info
Gene sequence info
Setaria_italica.CHS.fa
Download
>rna-XM_022828554.1
MDIDGPRVYEHKRAMGTASSLAIGTANPSNVMLQSDFPDFPDHIKEELKDRFRRICHLFAGQKSAIRKRHLYIDEALLGANPEMTTHGGPSLDKRKDIISAKIPELGAAAAAAALKEWGRTVVDITHLIVGCNSGGSDQPGADYHVARLLGLSPSASRLGVYHQGCVVGASTLCLAKDLAENNAGARVLAVLVEVSIIAIRGADSAAAAGDGSERPLFEIVRSRQLTVPGTGDAMRGLIREAGLTRGGSKMELHPGLNPPLGLTISLVREGPSMFASNLEAALRGFLGGSVTDGDWNALFWALHYPGGRLILDKVETALGLEPAKMRASREVLAEYGNMGSASVWFILDGMRRWSAANGCGTAGEGCHWGALCGFGPGLTLDLVLLRAARV
>rna-XM_004975116.1
MAAKVTVEEVRKAQRAEGPASVLAIGTVTPPNCVYQADYADYYFRVTKSEHMTELKEKFKRICRKSMIQKRYMHLTEDILLENPNMASYSAPSLNARQDILVEEVPKLGAAAAEKALKEWGQPRSQITHIIFCTTSGVDMPGADSRIIKLLGLDPSVKRVMLYHQGCFAGGMVLRIAKDLAENNRGARVLIVCSEITVVTFRGPSEAHLDSLVGQALFGDGAAAVIVGADPDEHVERPLFQMVSASETILPNSDGAIEGHLREVGLTFHLQERVPELISSNIERLLEESFKPLGISDWNSIFWVAHPGGPAILNAVESKAGIDKARLRATRQVLSEYGNMSSACVLFILDEMRKFSAEDGRATTGEGMDWGVLFGFGPGLTVETVVLHSVPITTGHAA
>rna-XM_004975115.1
MAAKVTVEEVRKAQRAEGPASVLAIGTVTPPNCVYQADYADYYFRVTKSEHMTELKEKFKRICRKSMIQKRYMHLTEDILLENPNMASYSAPSLNARQDILVEEVPKLGAAAVEKALKEWGQPRSQITHIIFCTTSGVDMPGADSRIIKLLGLDPSVKRVMLYHQGCFAGGMVLRIAKDLAENNRGARVLIVCSEITVVTFRGPSEAHLDSLVGQALFGDGAAAVIVGADPDEHVERPLFQMVSASETILPNSDGAIEGHLREVGLTFHLQERVPELISSNIERLLEESFKPLGISDWNSIFWVAHPGGPAILNAVESKAGIDKARLRATRQVLSEYGNMSSACVLFILDEMRKFSAEDGRATTGEGMDWGVLFGFGPGLTVETVVLHSVPITTGHAA
>rna-XM_004975113.1
MAAKVTVEEVRKAQRAEGPASVLAIGTVTPPNCVYQADYADYYFRVTKSEHMTELKEKFKRICRKSMIQKRYMHLTEDILLENPNMASYSAPSLNARQAILVEEVPKLGAAAAEKALKEWGQPRSQITHIIFCTTSGVDMPGADSRIIKLLGLDPSVKRVMLYHQGCFAGGMVLRIAKDLAENNRGARVLIVCSEITVVTFRGPSEAHLDSLVGQALFGDGAAAVIVGADPDEHVERPLFQMVSASETILPNSDGAIEGHLREVGLTFHLQERVPELISSNIERLLEESFKPLGISDWNSIFWVAHPGGPAILNAVESKAGIDKARLRATRQVLSEYGNMSSACVLFILDEMRKFSAEDGRATTGEGMDWGVLFGFGPGLTVETVVLHSVPITTGHAA
>rna-XM_014805673.2
MGSLMAPDASHPIGCPHEGGRATIMGIGTAVPSHEFQQKSFSDYYFEITSSNHMVDLKAKFANICEKTMIEKRHFYMSNEMLRDSPSITAYSSPSLTLRQELADVGVPELGAKAARLAISDWGKQASDITHLVASTSSSGCMPGADCELARLLGLKPSTKRFMLYQTGCHGGCTALGLSKDLAENNPGARVLVVCSEVCTLSLRGPSESHTGDLVGQAILGDAAGAVVVGSRPAADEHAMFELVLTCQETVPGTEEALVSKLREEGILYNLHRDIPLHVSSSTERLVKLMLQETLVPTLDLNDEVFWVVHPGGRGILDRIASKLGLREEKLAASRAVMRQYGNTRCSSVILVMEEMRRRSEELDRHTAGEGLDWGLLVGYGPGITVEAILLFALPDKAVNKLSVT
>rna-XM_004979334.3
MAGATVTVEEVRKAQRASGPATVLAIGTATPAHCVYQADYPDYYFRVTKSDHLTDLKEKFKRMCDKSMIRKRYMHLTEEFLNENPNMCAYMAPSLDARQDIVVVEVPKLGKAAAQKAIKEWGQPRSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVNRLMMYQQGCFAGGTVLRVAKDLAENNRGARVLVVCSEITAVTFRGPSESHLDSLVGQALFGDGAAAVIVGADPDESVERPLFQLVSASQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIERALEEAFKPLGISDWNSVFWVAHPGGPAILDQVEAKVGLDKARMRATRHVLSEYGNMSSACVLFILDEMRKRSAEDGHATTGEGFDWGVLFGFGPGLTVETVVLHSVPITAGTAA
MDIDGPRVYEHKRAMGTASSLAIGTANPSNVMLQSDFPDFPDHIKEELKDRFRRICHLFAGQKSAIRKRHLYIDEALLGANPEMTTHGGPSLDKRKDIISAKIPELGAAAAAAALKEWGRTVVDITHLIVGCNSGGSDQPGADYHVARLLGLSPSASRLGVYHQGCVVGASTLCLAKDLAENNAGARVLAVLVEVSIIAIRGADSAAAAGDGSERPLFEIVRSRQLTVPGTGDAMRGLIREAGLTRGGSKMELHPGLNPPLGLTISLVREGPSMFASNLEAALRGFLGGSVTDGDWNALFWALHYPGGRLILDKVETALGLEPAKMRASREVLAEYGNMGSASVWFILDGMRRWSAANGCGTAGEGCHWGALCGFGPGLTLDLVLLRAARV
>rna-XM_004975116.1
MAAKVTVEEVRKAQRAEGPASVLAIGTVTPPNCVYQADYADYYFRVTKSEHMTELKEKFKRICRKSMIQKRYMHLTEDILLENPNMASYSAPSLNARQDILVEEVPKLGAAAAEKALKEWGQPRSQITHIIFCTTSGVDMPGADSRIIKLLGLDPSVKRVMLYHQGCFAGGMVLRIAKDLAENNRGARVLIVCSEITVVTFRGPSEAHLDSLVGQALFGDGAAAVIVGADPDEHVERPLFQMVSASETILPNSDGAIEGHLREVGLTFHLQERVPELISSNIERLLEESFKPLGISDWNSIFWVAHPGGPAILNAVESKAGIDKARLRATRQVLSEYGNMSSACVLFILDEMRKFSAEDGRATTGEGMDWGVLFGFGPGLTVETVVLHSVPITTGHAA
>rna-XM_004975115.1
MAAKVTVEEVRKAQRAEGPASVLAIGTVTPPNCVYQADYADYYFRVTKSEHMTELKEKFKRICRKSMIQKRYMHLTEDILLENPNMASYSAPSLNARQDILVEEVPKLGAAAVEKALKEWGQPRSQITHIIFCTTSGVDMPGADSRIIKLLGLDPSVKRVMLYHQGCFAGGMVLRIAKDLAENNRGARVLIVCSEITVVTFRGPSEAHLDSLVGQALFGDGAAAVIVGADPDEHVERPLFQMVSASETILPNSDGAIEGHLREVGLTFHLQERVPELISSNIERLLEESFKPLGISDWNSIFWVAHPGGPAILNAVESKAGIDKARLRATRQVLSEYGNMSSACVLFILDEMRKFSAEDGRATTGEGMDWGVLFGFGPGLTVETVVLHSVPITTGHAA
>rna-XM_004975113.1
MAAKVTVEEVRKAQRAEGPASVLAIGTVTPPNCVYQADYADYYFRVTKSEHMTELKEKFKRICRKSMIQKRYMHLTEDILLENPNMASYSAPSLNARQAILVEEVPKLGAAAAEKALKEWGQPRSQITHIIFCTTSGVDMPGADSRIIKLLGLDPSVKRVMLYHQGCFAGGMVLRIAKDLAENNRGARVLIVCSEITVVTFRGPSEAHLDSLVGQALFGDGAAAVIVGADPDEHVERPLFQMVSASETILPNSDGAIEGHLREVGLTFHLQERVPELISSNIERLLEESFKPLGISDWNSIFWVAHPGGPAILNAVESKAGIDKARLRATRQVLSEYGNMSSACVLFILDEMRKFSAEDGRATTGEGMDWGVLFGFGPGLTVETVVLHSVPITTGHAA
>rna-XM_014805673.2
MGSLMAPDASHPIGCPHEGGRATIMGIGTAVPSHEFQQKSFSDYYFEITSSNHMVDLKAKFANICEKTMIEKRHFYMSNEMLRDSPSITAYSSPSLTLRQELADVGVPELGAKAARLAISDWGKQASDITHLVASTSSSGCMPGADCELARLLGLKPSTKRFMLYQTGCHGGCTALGLSKDLAENNPGARVLVVCSEVCTLSLRGPSESHTGDLVGQAILGDAAGAVVVGSRPAADEHAMFELVLTCQETVPGTEEALVSKLREEGILYNLHRDIPLHVSSSTERLVKLMLQETLVPTLDLNDEVFWVVHPGGRGILDRIASKLGLREEKLAASRAVMRQYGNTRCSSVILVMEEMRRRSEELDRHTAGEGLDWGLLVGYGPGITVEAILLFALPDKAVNKLSVT
>rna-XM_004979334.3
MAGATVTVEEVRKAQRASGPATVLAIGTATPAHCVYQADYPDYYFRVTKSDHLTDLKEKFKRMCDKSMIRKRYMHLTEEFLNENPNMCAYMAPSLDARQDIVVVEVPKLGKAAAQKAIKEWGQPRSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVNRLMMYQQGCFAGGTVLRVAKDLAENNRGARVLVVCSEITAVTFRGPSESHLDSLVGQALFGDGAAAVIVGADPDESVERPLFQLVSASQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIERALEEAFKPLGISDWNSVFWVAHPGGPAILDQVEAKVGLDKARMRATRHVLSEYGNMSSACVLFILDEMRKRSAEDGHATTGEGFDWGVLFGFGPGLTVETVVLHSVPITAGTAA
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University