Enzyme
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
ROMT
Enzyme
Trans-resveratrol di-O-methyltransferase
Enzyme name
EC:2.1.1.240
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase
Sysname
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction) [RN:R09872];(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene [RN:R09870];(1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene [RN:R09871]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];pterostilbene [CPD:C10287];3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Product
Species information
Sechium edule
Species name
Chayote (Sicyos edulis) is a species of eudicot in the family Cucurbitaceae (cucumber family).
Species info
Gene sequence info
Sechium_edule.ROMT.fa
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>Sed0000416.1
MNLEGGNMAVVAGNDELLKAQSHIWNHIFSFINSMSLKCAVQLMIPDAIHNHGLHPMPLSQLVSVLELHPNKTRFIYRLMRLLTHSGFFQIQNVTKSSGEEEEGYVLTNSSRLLIRDNPLSLAPFLLSILDPFLMEPWQFLSTWFRSDDRTPYDTAHGMPIWEYLSNMGKYGEVFNEAMASDARLVMSILVEKYKYVFDGVDILVDVGGGTGTVAKAIAEAFPQVQCIVFDLPQVVGGMKLGQENFKCVAGDMFQAIPSGDAFILKWILHNWSNEECIKILKNCKLAMTSNSSKKKVIVIDMVVESKEKDSSIETQLFMDMQMMVLTAGKEREQKEWAQLIKEAGFNSYAISPIIGSRSLIEIYP
>Sed0015569.1
MSLEGGNMETVVGDELLEAQAHIWKRIFSFINSMALKCAIQLEIPDAIHRHGPHPMPLSQLVSALQLNPNKTQLVYRLMRLLTHSGFFQVTRNCENKEEEYMLTNSSRLLIRDNPLSLAPFVSGMLEPFFMEPWHFLATWFRSDDQTPFDTTHEMPFWKCLGDMPKYGDVFNAAMAGDARLVMRVLIEKYGDVFNGVGILVDVGGGTGTMAEAIAQAFPQIECIVFDLPQVVGAIKGEQNSKYVAGDMFEAIPSADAFLLKWILHDWSDEECVRILKNCKSAMRSNGKKKKVIVIDMVVGSKKKDASIETQLFFDLQMMATATGKEREEKEWAQLIKEAEFSSYKISPIIALRSLIEIYPRVSRFKKKKKCLFEYILYFCVKYLFDY
>Sed0012403.1
MNMNMNLEGGKMAMAAGDELLEAQAHIWKHIFSFINSMCLKCAVQLGIPDAIHSHGPHPMPLSQLISALQLHPNKTAFVYRLMRLLTHSNFFRVIQNSEQEEEGYTLTDSSRLLLKDNPLSVAPFLSPMLDPVFVEPWQFLSAWMKSDDQTSFDTAHGTPVWEYFSNNPKHGDAFNEAMASDARLVIHILLNKYKHIFDGLGSLVDVGGGTGTIAKAAAEAFPETECIVLDLPQVVADLKGERNLKFVAGDMFKDIPPADALVMKWILHEMNDEECVRVLKNCKSAITSNGKKLGKVIVIGMVVDSKKEDSIGIQMLFDMLLMALTIGKERGEKEWAYVIKEAGFSRYKISPIMGLRSVIEIYP
>Sed0018921.1
MNMDSSVELLEARAHIWNHIFNFIDSMSLKSLQLHPNKTPFVYRLMRILTHSGFFKSQKLTINDEEEEGYSLTNSSRLLVKDKPCNLTSFVLLQLENAFFEPWQFLAAWFRTEDLTPFDTTHGTPFWEHMGNERKDGDIFNAAMASDARLVACVLVGKYRSFFDGIGSLVDVGGGTGTLAKAIAEAFPEMECVVFDKPQVVANLKGETNLTYLGGDMFQAIPPADALLLKWILHDWSDEECVKILKKCKLAITQNDNKGKVIIIDVVVSNKEKDNYIQTQLLWDMLMMVNVGGKEREENEWAQLIKEAGFSIYKIFPILGLRSLIEIYP
>Sed0006157.1
MALVAGDELLEAQAHIWNHIFNFINSMSLKCAVQLGIPDAIDLHGTQPMALSQLVSALQLHPNKTPFVYRLMRILTHSGFFTSQKLTINDEQEEGYSLTNSSRLLLKNNPFSITPFLLSMLESTLLDPWQLLAAWFRTDDRTPFETAHGMPFWEHMGDKPKDGEIFNAAMESDARLVMSALLGKYKSVFDGIGSLVDVGGGNGSLTKVIAKAFPEIECIVFDLPQVVGGFKGQTNFKYVEGDMFQAIPPADALLLKWILHDWNDEECVRILKKCKLAITCNGKKGKVIVIDIVISNKKKDESIETQLLWDMLMMVNVGGKERQEKEWTQLIKQAGFSTCNIFPIMGFRSLIEIYP
>Sed0009114.1
MDFTESISTFLFDMNMDSSDELLAAQAHIWNHIFHFINSMSLKCAVQLGIPDAIDRHGSRPMALSQLVSALQLHPNKTPFVYRLMRKLTHSGFFTSQKLTINDKEEEEGYSLTNSSRLLLKDNPFAVTPFLLSMLESSLLEPWKFLAAWFRTDDRTPFDTAHGMPIWKFMGIESKDGDVFNAGMASDARLVMRVLLSKYKSVFEGIGSLVDVGGGTGTVAKAIADSFPEIECIVFDLPQVVNDLKGQNNFKYIGGDMFQAIPPADALFLKWILHDWSDEECVEILKKCKLAITNNNGKGKVMVIDMVVSNKNKDDMAESQLFFDMLMMILLGGKEREEKEWAGLIKEAGFSSYKISPIVGLRSLIEIYP
>Sed0014511.1
MAVIAGDDLLKAQSHICNHSYMFVNSMALKCAVQLGIPDAIDRHGPNPMPLSQLVSALQLHTQKTNYIYRLMRVLVHSGFFSIQKVTSEKGQEEEEGYVLTNSSRLLVKNNPLTLAPFVLSVLEPGLINSLRSLPAWLQSEDPTPFDTAHGVSFWEYMKTNASTEGGMFIASMESDAKLVISILLEKYKGMFDGIDSLVDVGGGTGMVAKAIAEAFPKMECTVFDLPQVVADLKGKENLKYVAGDMFEIIPSGDVLVLKWILHDWNDEECVKILKKCKKAIASKEGKKGKVIVIDMVVDSEKRDDSIETQLCFDMAMMLIVDGKERNEKEWAQLIKEAEFSDYKIFPILGLRSLIEIYP
>Sed0017563.1
MAVIAGDDFLKAQSHICNHSYMFVNSMALKCAVQLGIPDAIDRHGPNPMPLSQLVSALQLHTQKTNYIYRLMRVLVHSGFFSIQKVTSEKGQEEEEGYVLTNSSRLLVKNNPLTLAPFVLSVLEPGLINSLRSLPAWLQSEDPTPFDTAHGVSFWEYMKTNASTEGGMFIASMESDAKLVISILLEKYKGMFDGIDSLVDVGGGTGMVAKAIAEAFPKMECTVFDLPQVVADLKGKENLKYVAGDMFEVIPSGDVLVLKWVLHDWNDEECVKILKKCKEAIASKEGKKGKVIIIDMVVDNEKRDDSIETQLCSDMTMMLLVDGKERNEKEWARLIKEAEFSDYKIFPILGLRSLIEIYP
>Sed0024387.1
MDYTKISIQEFLFDINMDSNDRKMELIEGDELLEAQAHIWNHIFNFINSMSLKCAVELGIPDAIHSHGSQPVALPQLVSALQLHPDKTPFVYRLMRILTHSGFFVSQKVTIDGAEEEEGYSLTNSSHLLLKDNPCSVVPFLLLQSKEAFLDKWQLLAAWFRTDDRTPFDTTYGMPFWERMGDKPKDGDNFNAAMESDAKLVVSVLLGKYKDVFEGIGSLVDVGGGIGTMAKAIAQTFPNIECTVFDLSQVVADLKGERNLKYVEGDMFQAIPPADAILLKWILHDWSDQECVKILKKCKLAITLNGNKGKVIVIDMVVGNKKNDNSIETQLFWDMLMMVTMGGREREEKEWVQLIKEAGFSTYKIFPIIGLRSLIEIYP
>Sed0000660.1
MGENKDLLAAQAHIWNHTFKYINSMSLKCRIQLGIPDIIHSHGQPMTLSNLVSSLKIQPSKAHCLLRHVDNTLETSPFVFVALHRAMMAPWEGMSRWLCSEDHECCYSTAFEMVNDGKSIWHYMVEDSDFDCKEVFLGLKSLADVGGGDGTMAKVIVDEFPQIACIVFDLPQVVLNHQQTARNLKFVGGDMFEDKIPPADAVLLKLGLGKVIIIEAVLENQIEDKESTETQLCGDVLMMASFTSRKRNKTEWKNLFLAAGLSGYKVTSFMGLRSLIEVYP
MNLEGGNMAVVAGNDELLKAQSHIWNHIFSFINSMSLKCAVQLMIPDAIHNHGLHPMPLSQLVSVLELHPNKTRFIYRLMRLLTHSGFFQIQNVTKSSGEEEEGYVLTNSSRLLIRDNPLSLAPFLLSILDPFLMEPWQFLSTWFRSDDRTPYDTAHGMPIWEYLSNMGKYGEVFNEAMASDARLVMSILVEKYKYVFDGVDILVDVGGGTGTVAKAIAEAFPQVQCIVFDLPQVVGGMKLGQENFKCVAGDMFQAIPSGDAFILKWILHNWSNEECIKILKNCKLAMTSNSSKKKVIVIDMVVESKEKDSSIETQLFMDMQMMVLTAGKEREQKEWAQLIKEAGFNSYAISPIIGSRSLIEIYP
>Sed0015569.1
MSLEGGNMETVVGDELLEAQAHIWKRIFSFINSMALKCAIQLEIPDAIHRHGPHPMPLSQLVSALQLNPNKTQLVYRLMRLLTHSGFFQVTRNCENKEEEYMLTNSSRLLIRDNPLSLAPFVSGMLEPFFMEPWHFLATWFRSDDQTPFDTTHEMPFWKCLGDMPKYGDVFNAAMAGDARLVMRVLIEKYGDVFNGVGILVDVGGGTGTMAEAIAQAFPQIECIVFDLPQVVGAIKGEQNSKYVAGDMFEAIPSADAFLLKWILHDWSDEECVRILKNCKSAMRSNGKKKKVIVIDMVVGSKKKDASIETQLFFDLQMMATATGKEREEKEWAQLIKEAEFSSYKISPIIALRSLIEIYPRVSRFKKKKKCLFEYILYFCVKYLFDY
>Sed0012403.1
MNMNMNLEGGKMAMAAGDELLEAQAHIWKHIFSFINSMCLKCAVQLGIPDAIHSHGPHPMPLSQLISALQLHPNKTAFVYRLMRLLTHSNFFRVIQNSEQEEEGYTLTDSSRLLLKDNPLSVAPFLSPMLDPVFVEPWQFLSAWMKSDDQTSFDTAHGTPVWEYFSNNPKHGDAFNEAMASDARLVIHILLNKYKHIFDGLGSLVDVGGGTGTIAKAAAEAFPETECIVLDLPQVVADLKGERNLKFVAGDMFKDIPPADALVMKWILHEMNDEECVRVLKNCKSAITSNGKKLGKVIVIGMVVDSKKEDSIGIQMLFDMLLMALTIGKERGEKEWAYVIKEAGFSRYKISPIMGLRSVIEIYP
>Sed0018921.1
MNMDSSVELLEARAHIWNHIFNFIDSMSLKSLQLHPNKTPFVYRLMRILTHSGFFKSQKLTINDEEEEGYSLTNSSRLLVKDKPCNLTSFVLLQLENAFFEPWQFLAAWFRTEDLTPFDTTHGTPFWEHMGNERKDGDIFNAAMASDARLVACVLVGKYRSFFDGIGSLVDVGGGTGTLAKAIAEAFPEMECVVFDKPQVVANLKGETNLTYLGGDMFQAIPPADALLLKWILHDWSDEECVKILKKCKLAITQNDNKGKVIIIDVVVSNKEKDNYIQTQLLWDMLMMVNVGGKEREENEWAQLIKEAGFSIYKIFPILGLRSLIEIYP
>Sed0006157.1
MALVAGDELLEAQAHIWNHIFNFINSMSLKCAVQLGIPDAIDLHGTQPMALSQLVSALQLHPNKTPFVYRLMRILTHSGFFTSQKLTINDEQEEGYSLTNSSRLLLKNNPFSITPFLLSMLESTLLDPWQLLAAWFRTDDRTPFETAHGMPFWEHMGDKPKDGEIFNAAMESDARLVMSALLGKYKSVFDGIGSLVDVGGGNGSLTKVIAKAFPEIECIVFDLPQVVGGFKGQTNFKYVEGDMFQAIPPADALLLKWILHDWNDEECVRILKKCKLAITCNGKKGKVIVIDIVISNKKKDESIETQLLWDMLMMVNVGGKERQEKEWTQLIKQAGFSTCNIFPIMGFRSLIEIYP
>Sed0009114.1
MDFTESISTFLFDMNMDSSDELLAAQAHIWNHIFHFINSMSLKCAVQLGIPDAIDRHGSRPMALSQLVSALQLHPNKTPFVYRLMRKLTHSGFFTSQKLTINDKEEEEGYSLTNSSRLLLKDNPFAVTPFLLSMLESSLLEPWKFLAAWFRTDDRTPFDTAHGMPIWKFMGIESKDGDVFNAGMASDARLVMRVLLSKYKSVFEGIGSLVDVGGGTGTVAKAIADSFPEIECIVFDLPQVVNDLKGQNNFKYIGGDMFQAIPPADALFLKWILHDWSDEECVEILKKCKLAITNNNGKGKVMVIDMVVSNKNKDDMAESQLFFDMLMMILLGGKEREEKEWAGLIKEAGFSSYKISPIVGLRSLIEIYP
>Sed0014511.1
MAVIAGDDLLKAQSHICNHSYMFVNSMALKCAVQLGIPDAIDRHGPNPMPLSQLVSALQLHTQKTNYIYRLMRVLVHSGFFSIQKVTSEKGQEEEEGYVLTNSSRLLVKNNPLTLAPFVLSVLEPGLINSLRSLPAWLQSEDPTPFDTAHGVSFWEYMKTNASTEGGMFIASMESDAKLVISILLEKYKGMFDGIDSLVDVGGGTGMVAKAIAEAFPKMECTVFDLPQVVADLKGKENLKYVAGDMFEIIPSGDVLVLKWILHDWNDEECVKILKKCKKAIASKEGKKGKVIVIDMVVDSEKRDDSIETQLCFDMAMMLIVDGKERNEKEWAQLIKEAEFSDYKIFPILGLRSLIEIYP
>Sed0017563.1
MAVIAGDDFLKAQSHICNHSYMFVNSMALKCAVQLGIPDAIDRHGPNPMPLSQLVSALQLHTQKTNYIYRLMRVLVHSGFFSIQKVTSEKGQEEEEGYVLTNSSRLLVKNNPLTLAPFVLSVLEPGLINSLRSLPAWLQSEDPTPFDTAHGVSFWEYMKTNASTEGGMFIASMESDAKLVISILLEKYKGMFDGIDSLVDVGGGTGMVAKAIAEAFPKMECTVFDLPQVVADLKGKENLKYVAGDMFEVIPSGDVLVLKWVLHDWNDEECVKILKKCKEAIASKEGKKGKVIIIDMVVDNEKRDDSIETQLCSDMTMMLLVDGKERNEKEWARLIKEAEFSDYKIFPILGLRSLIEIYP
>Sed0024387.1
MDYTKISIQEFLFDINMDSNDRKMELIEGDELLEAQAHIWNHIFNFINSMSLKCAVELGIPDAIHSHGSQPVALPQLVSALQLHPDKTPFVYRLMRILTHSGFFVSQKVTIDGAEEEEGYSLTNSSHLLLKDNPCSVVPFLLLQSKEAFLDKWQLLAAWFRTDDRTPFDTTYGMPFWERMGDKPKDGDNFNAAMESDAKLVVSVLLGKYKDVFEGIGSLVDVGGGIGTMAKAIAQTFPNIECTVFDLSQVVADLKGERNLKYVEGDMFQAIPPADAILLKWILHDWSDQECVKILKKCKLAITLNGNKGKVIVIDMVVGNKKNDNSIETQLFWDMLMMVTMGGREREEKEWVQLIKEAGFSTYKIFPIIGLRSLIEIYP
>Sed0000660.1
MGENKDLLAAQAHIWNHTFKYINSMSLKCRIQLGIPDIIHSHGQPMTLSNLVSSLKIQPSKAHCLLRHVDNTLETSPFVFVALHRAMMAPWEGMSRWLCSEDHECCYSTAFEMVNDGKSIWHYMVEDSDFDCKEVFLGLKSLADVGGGDGTMAKVIVDEFPQIACIVFDLPQVVLNHQQTARNLKFVGGDMFEDKIPPADAVLLKLGLGKVIIIEAVLENQIEDKESTETQLCGDVLMMASFTSRKRNKTEWKNLFLAAGLSGYKVTSFMGLRSLIEVYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University