Enzyme
A cytochrome P-450 (heme-thiolate) protein found in plants. The enzyme is involved in flavonoid biosynthesis.
C4H
Enzyme
Cinnamate 4-hydroxylase
Enzyme name
EC:1.14.14.91
Entry
Oxidoreductases;Acting on paired donors, with incorporation or reduction of molecular oxygen;With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
Class
trans-cinnamate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating)
Sysname
trans-cinnamate + [reduced NADPH---hemoprotein reductase] + O2 = 4-hydroxycinnamate + [oxidized NADPH---hemoprotein reductase] + H2O[RN:R02253]
Reaction
4-hydroxycinnamate [CPD:C00811];[oxidized NADPH---hemoprotein reductase] [CPD:C03161];H2O [CPD:C00001]
Product
Species information
Secale cereale
Species name
Rye (Secale cereale) is a species of monocot in the family Poaceae (grass family).
Species info
Gene sequence info
Secale_cereale.C4H.fa
Download
>ScWN2R01G331800.1
MGVVRHRNLAALARRFGEIFLLRMGHRNVVVVSSPALAREVLHARGAEFGSRGRNVVFDVFTDGGQDMVFAAYGDHWHTMRRVMTAPFFTGNVVQRHHAGWEAEAAAVVDAVRADPAAATGGVVLRRHMQLLMYNNMYGLMFGRRFEGLDDPLLLRLRELNGERSRLAQSFEYNYGDFIPVLRPFLRGYLRICKEVKDARLKLYKDCFVEERRKMLANGKATDSHELKCGMDEILEAQRKGEINEDHVLFIVENINVAAIETTLWAMEWAVAELVNHPETQQKLRREMDAVLGAGHQVTEPDTHRLPYLQAVVKEALRLHMAIPLLVPHMNLCDAELGGHGVPAESKVLVNAWHLANDPGLWERPGEFRPERFLEEERHVEAGGNDFRYLPFGAGRRSCPGIVLALPFLCITVGRLVQNFELLPPPGQDMLDTTEKGGQFSLHILKHSTIVAKPRVF
>ScWN2R01G332000.1
MGHRNVVVVSSPALAREVLHARGAEFGSRGRNVVFDVFTDGGQDMVFAAYGDHWHTMRRVMTAPFFTGNVVQRHHAGWEAEAAAVVDAVRADPAAATGGVVLRRHMQLLMYNNMYGLMFGRRFEGLDDPLLLRLRELNGERSRLAQSFEYNYGDFIPVLRPFLRGYLRICKEVKDARLKLYKDCFVEERRKMLANGKATDSHELKCGMDEILEAQRKGEINEDHVLFIVENINVAAIETTLWAMEWAVAELVNHPETQQKLRREMDAVLGAGHQVTEPDTHRLPYLQAVVKEALRLHMAIPLLVPHMNLCDAELGGHGAPAESKVLVNAWHLANDPGLWERPGEFRPERFLEEERHVEAGGNDFRYLPFGAGRRSCPGIVLALPFLCITVGRLVQNFELLAMLDTTEKGGQFSLHILKHSTIVAKPRAFYLDQHPLEYGVEGFPALSFTSLQAQQRGYWFSWR
>ScWN3R01G201900.1
MDVLLLEKALLGLFAAAVLAIAVAKLTGKRLRLPPGPSGAPIVGNWLQVGDDLNHRNLMDMAKRFGEVFLLRMGVRNLVVVSSPELAKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVAQNRVGWEEEARLVVEDLKANPASATEGVVVRRRLQLMMYNDMFRIMFDRRFESVDDPLFNKLKALNAERSILSQSFDYNYGDFIPVLRPFLRRYLNRCTNLKTKRMKVFEDHFVQQRKEALEKTGEIRCAMDHILEAERKGEINHDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQQKLREEIVAVLGPGTAVTEPDLERLPYLQSVVKETLRLRMAIPLLVPHMNLSDAKLAGYDIPAESKILVNAWFLANDPKRWVRADEFRPERFLEEEKAVEAHGNDFRFVPFGVGRRSCPGIILALPIIGITLGRLVQNFQLLPPPGQDKIDTTEKPGQFSNQILKHATIVCKPLEA
>ScWN3R01G202000.1
MDVLLLEKALLGLFAAAVLAIAVAKLTGKRLRLPPGPSGAPIVGNWLQVGDDLNHRNLMDMAKRFGEVFLLRMGVRNLVVVSSPELAKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVAQNRVGWEEEARLVVEDLKANPASATEGVVVRRRLQLMMYNDMFRIMFDRRFESVDDPLFNKLKALNAERSILSQSFDYNYGDFIPVLRPFLRRYLNRCTNLKTKRMKVFEDHFVQQRKEALEKTGEIRCAMDHILEAERKGEINHDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQQKLREEIVAVLGPGTAVTEPDLERLPYLQSVVKETLRLRMAIPLLVPHMNLSDAKLAGYDIPAESKILVNAWFLANDPKRWVRADEFRPERFLEEEKAVEAHGNDFRFVPFGVGRRSCPGIILALPIIGITLGRLVQNFQLLPPPGQDKIDTTEKPGQFSNQILKHATIVCKPLEA
>ScWN3R01G425900.1
MDFVFVEKLLVGLLAAVVGAIVVSKIRGRKLRLPPGPIPVPIFGNWLQVGDDLNHRNLAAMARKFGEVFLLRMGQRNLVVVSSPPLAREVLHTQGVEFGSRTRNVVFDIFTGEGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVQQYRPGWEAEAAFVVDNVRADPKAATEGVVLRRHLQLMMYNNMYRIMFDRRFESMDDPLFLRLRALNGERSRLAQSFEYNYGDFIPILRPFLRGYLRLCKEVKETRLKLFKDYFLDERKKLVSSKSVDNNGGLKCAIDHILEAEQKGEINEDNVLYIIENINVAAIETTLWSIEWGLAELVNHPEIQQKLRDEMDAVLGVGHQITEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLAGYNIPAESKILVNAWFLANNPEQWRRPDEFRPERFLEEEKHVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFVLTPPPGQDKLDTTEKGGQFSLHILKHSTIVAKPRVF
>ScWN5R01G638700.1
MDVNLLEKALLGLFVAAMLAIAVAKLTGKRFRLPPGPPGAPIVGNWLQVGDDLNHRNLMGMAKRFGEVFLLRMGVRNLVVVSSPELAKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVVQNRVGWEEEARLVVEDLKADPASATGVVIRRRLQLMMYNDMFRIMFDRRFESLADPLFNKLRALNAERSMLSQSFDYNYGDFIPILRPFLRGYLNRCTNLKAKRMKVFEDHFVQERKKALEKNGEIRCAMDHILEAERKGEINHDNVLYIVENINVAAIETTLWSIEWGVAELVNHPDIQSKLRHEIAAVLGPDAAVTEPDLERLPYLQAVVKETLRLRMAIPLLVPHMNLKDAKLAGYDIPAESKILVNAWFLANDPKRWVRADEFRPERFLEEERSVEANGNDFRFVPFGVGRRSCPGIILAMPIIGITLGRLVQNFQLLPPLGQDKIDTTEKPGQFSNQIRNHATVVCKPLKA
>ScWN5R01G638500.1
MTSITATSWAWPSASARCSSYAWASATWWSSPVLSSPRRCSTPRASSSAPAPATSSSTSLPAKARTWCSQCTATTGARCRIMTVPFFTNKVVVQNREGWEEEARLVVEDLKADPASATGVVIRRRLQLMMYNDMFRIMFDRRFESLADPLFNKLRALNAERSMLSQSFDYNYGDFIPILRPFLRGYLNRCTNLKAKRMKVFEDHFVQERKKALEKNGEIRCAMDHILEAERKGEINHDNVLYIVENINVAAIETTLWSIEWGVAELVNHPDIQSKLRHEIAAVLGPDAAVTEPDLERLPYLQAVVKETLRLRMAIPLLVPHMNLKDAKLTGYDIPAESKILVNAWFLANDPKRWVRADEFRPERFLEEERSVEANGNDFRFVPFGVGRRSCPGIILAMPIIGITLGRLVQNFQLLPPLGQDKIDTTEKPGQFSNQIRNHATVVCKPLKA
>ScWN7R01G393200.1
MATSARRVAFAAAASLAVYWLLKSFLHAPHPALLPATAALVAVAITVGAGGKRGSAPPGPAAVPVFGNWLQVGNDLNHRFLARLSARYGPVFRLRLGVRNLVVVSDPRLATEVLHTQGVEFGSRPRNVVFDIFTANGADMVFTEYGDHWRRMRRVMTLPFFTARVVQQYRAMWEAEMDDVVSDLRGDSAARGAGVVVRRRLQLMLYNIMYRMMFDARFESVDDPMFVEATKFNSERSRLAQSFDYNYGDFIPILRPFLRGYLNRCRDLQTRRLAFFNANYVEKRRKVMETPGEDKNKLRCAIDHVLAAEKSGEITPENVIYIVENINVAAIETTLWSIEWALAEVVNHPDVQRKVRGEIRDVLGDDEPIAESSISKLPYLQAVIKETLRLHSPIPLLVPHMNLEEASLGGYTIPKGSKVVVNAWWLANNPELWEKPEEFRPERFLGEESNVDATVGGGKVDFRFLPFGVGRRSCPGIILALPILALIVGKLVRSFEMVPPPGVDKLDVSEKGGQFSLHIANHSLITFHPIVSP
MGVVRHRNLAALARRFGEIFLLRMGHRNVVVVSSPALAREVLHARGAEFGSRGRNVVFDVFTDGGQDMVFAAYGDHWHTMRRVMTAPFFTGNVVQRHHAGWEAEAAAVVDAVRADPAAATGGVVLRRHMQLLMYNNMYGLMFGRRFEGLDDPLLLRLRELNGERSRLAQSFEYNYGDFIPVLRPFLRGYLRICKEVKDARLKLYKDCFVEERRKMLANGKATDSHELKCGMDEILEAQRKGEINEDHVLFIVENINVAAIETTLWAMEWAVAELVNHPETQQKLRREMDAVLGAGHQVTEPDTHRLPYLQAVVKEALRLHMAIPLLVPHMNLCDAELGGHGVPAESKVLVNAWHLANDPGLWERPGEFRPERFLEEERHVEAGGNDFRYLPFGAGRRSCPGIVLALPFLCITVGRLVQNFELLPPPGQDMLDTTEKGGQFSLHILKHSTIVAKPRVF
>ScWN2R01G332000.1
MGHRNVVVVSSPALAREVLHARGAEFGSRGRNVVFDVFTDGGQDMVFAAYGDHWHTMRRVMTAPFFTGNVVQRHHAGWEAEAAAVVDAVRADPAAATGGVVLRRHMQLLMYNNMYGLMFGRRFEGLDDPLLLRLRELNGERSRLAQSFEYNYGDFIPVLRPFLRGYLRICKEVKDARLKLYKDCFVEERRKMLANGKATDSHELKCGMDEILEAQRKGEINEDHVLFIVENINVAAIETTLWAMEWAVAELVNHPETQQKLRREMDAVLGAGHQVTEPDTHRLPYLQAVVKEALRLHMAIPLLVPHMNLCDAELGGHGAPAESKVLVNAWHLANDPGLWERPGEFRPERFLEEERHVEAGGNDFRYLPFGAGRRSCPGIVLALPFLCITVGRLVQNFELLAMLDTTEKGGQFSLHILKHSTIVAKPRAFYLDQHPLEYGVEGFPALSFTSLQAQQRGYWFSWR
>ScWN3R01G201900.1
MDVLLLEKALLGLFAAAVLAIAVAKLTGKRLRLPPGPSGAPIVGNWLQVGDDLNHRNLMDMAKRFGEVFLLRMGVRNLVVVSSPELAKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVAQNRVGWEEEARLVVEDLKANPASATEGVVVRRRLQLMMYNDMFRIMFDRRFESVDDPLFNKLKALNAERSILSQSFDYNYGDFIPVLRPFLRRYLNRCTNLKTKRMKVFEDHFVQQRKEALEKTGEIRCAMDHILEAERKGEINHDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQQKLREEIVAVLGPGTAVTEPDLERLPYLQSVVKETLRLRMAIPLLVPHMNLSDAKLAGYDIPAESKILVNAWFLANDPKRWVRADEFRPERFLEEEKAVEAHGNDFRFVPFGVGRRSCPGIILALPIIGITLGRLVQNFQLLPPPGQDKIDTTEKPGQFSNQILKHATIVCKPLEA
>ScWN3R01G202000.1
MDVLLLEKALLGLFAAAVLAIAVAKLTGKRLRLPPGPSGAPIVGNWLQVGDDLNHRNLMDMAKRFGEVFLLRMGVRNLVVVSSPELAKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVAQNRVGWEEEARLVVEDLKANPASATEGVVVRRRLQLMMYNDMFRIMFDRRFESVDDPLFNKLKALNAERSILSQSFDYNYGDFIPVLRPFLRRYLNRCTNLKTKRMKVFEDHFVQQRKEALEKTGEIRCAMDHILEAERKGEINHDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQQKLREEIVAVLGPGTAVTEPDLERLPYLQSVVKETLRLRMAIPLLVPHMNLSDAKLAGYDIPAESKILVNAWFLANDPKRWVRADEFRPERFLEEEKAVEAHGNDFRFVPFGVGRRSCPGIILALPIIGITLGRLVQNFQLLPPPGQDKIDTTEKPGQFSNQILKHATIVCKPLEA
>ScWN3R01G425900.1
MDFVFVEKLLVGLLAAVVGAIVVSKIRGRKLRLPPGPIPVPIFGNWLQVGDDLNHRNLAAMARKFGEVFLLRMGQRNLVVVSSPPLAREVLHTQGVEFGSRTRNVVFDIFTGEGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVQQYRPGWEAEAAFVVDNVRADPKAATEGVVLRRHLQLMMYNNMYRIMFDRRFESMDDPLFLRLRALNGERSRLAQSFEYNYGDFIPILRPFLRGYLRLCKEVKETRLKLFKDYFLDERKKLVSSKSVDNNGGLKCAIDHILEAEQKGEINEDNVLYIIENINVAAIETTLWSIEWGLAELVNHPEIQQKLRDEMDAVLGVGHQITEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLAGYNIPAESKILVNAWFLANNPEQWRRPDEFRPERFLEEEKHVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNFVLTPPPGQDKLDTTEKGGQFSLHILKHSTIVAKPRVF
>ScWN5R01G638700.1
MDVNLLEKALLGLFVAAMLAIAVAKLTGKRFRLPPGPPGAPIVGNWLQVGDDLNHRNLMGMAKRFGEVFLLRMGVRNLVVVSSPELAKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVVQNRVGWEEEARLVVEDLKADPASATGVVIRRRLQLMMYNDMFRIMFDRRFESLADPLFNKLRALNAERSMLSQSFDYNYGDFIPILRPFLRGYLNRCTNLKAKRMKVFEDHFVQERKKALEKNGEIRCAMDHILEAERKGEINHDNVLYIVENINVAAIETTLWSIEWGVAELVNHPDIQSKLRHEIAAVLGPDAAVTEPDLERLPYLQAVVKETLRLRMAIPLLVPHMNLKDAKLAGYDIPAESKILVNAWFLANDPKRWVRADEFRPERFLEEERSVEANGNDFRFVPFGVGRRSCPGIILAMPIIGITLGRLVQNFQLLPPLGQDKIDTTEKPGQFSNQIRNHATVVCKPLKA
>ScWN5R01G638500.1
MTSITATSWAWPSASARCSSYAWASATWWSSPVLSSPRRCSTPRASSSAPAPATSSSTSLPAKARTWCSQCTATTGARCRIMTVPFFTNKVVVQNREGWEEEARLVVEDLKADPASATGVVIRRRLQLMMYNDMFRIMFDRRFESLADPLFNKLRALNAERSMLSQSFDYNYGDFIPILRPFLRGYLNRCTNLKAKRMKVFEDHFVQERKKALEKNGEIRCAMDHILEAERKGEINHDNVLYIVENINVAAIETTLWSIEWGVAELVNHPDIQSKLRHEIAAVLGPDAAVTEPDLERLPYLQAVVKETLRLRMAIPLLVPHMNLKDAKLTGYDIPAESKILVNAWFLANDPKRWVRADEFRPERFLEEERSVEANGNDFRFVPFGVGRRSCPGIILAMPIIGITLGRLVQNFQLLPPLGQDKIDTTEKPGQFSNQIRNHATVVCKPLKA
>ScWN7R01G393200.1
MATSARRVAFAAAASLAVYWLLKSFLHAPHPALLPATAALVAVAITVGAGGKRGSAPPGPAAVPVFGNWLQVGNDLNHRFLARLSARYGPVFRLRLGVRNLVVVSDPRLATEVLHTQGVEFGSRPRNVVFDIFTANGADMVFTEYGDHWRRMRRVMTLPFFTARVVQQYRAMWEAEMDDVVSDLRGDSAARGAGVVVRRRLQLMLYNIMYRMMFDARFESVDDPMFVEATKFNSERSRLAQSFDYNYGDFIPILRPFLRGYLNRCRDLQTRRLAFFNANYVEKRRKVMETPGEDKNKLRCAIDHVLAAEKSGEITPENVIYIVENINVAAIETTLWSIEWALAEVVNHPDVQRKVRGEIRDVLGDDEPIAESSISKLPYLQAVIKETLRLHSPIPLLVPHMNLEEASLGGYTIPKGSKVVVNAWWLANNPELWEKPEEFRPERFLGEESNVDATVGGGKVDFRFLPFGVGRRSCPGIILALPILALIVGKLVRSFEMVPPPGVDKLDVSEKGGQFSLHIANHSLITFHPIVSP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University