Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Scutellaria baicalensis
Species name
Baikal skullcap (Scutellaria baicalensis) is a species of eudicot in the family Lamiaceae (mint family).
Species info
Gene sequence info
Scutellaria_baicalensis.CHS.fa
Download
>Sb06t28780.mRNA1
MASEESMKNAAILALGKAFPHQLVLQDFLVDAYFRTTNRDDPDLKQKLTRLCKTTSVKTRYVVMSEEILEKYPELAMEGIPTVKQRLDICNSAVTEMAIEASKSCIQKWGGSLSRITHLVYVSSSEARLPGGDLYLAKGLGLRPDTQRVMLYFSGCSGGVAGLRVAKDIAENNPGSRVLVATSETTIIGYRPPSADRPYDLVGVALFGDGAGAMIIGSSPDLATETPLFELHTSLQHFLPDTEKIIDGKLTEEGISFRLDRELPEIIESNIEEFCVELMGFAGFDEKDYNKLFWAVHPGGPAILNKVEKKLELWPEKLSASRRALADYGNASSNTIVYVLEYMLEEAKNGKNGASPWGLILAFGPGITFEGILTRNLTL
>Sb09t03390.mRNA1
MVTVEEFHRATRAEGPATVLAIGTANPPNCVEQSTYADYYFRICKSEHLTDLKKKFSRMCEKSGIKKRYMHLTEEFLKENDNFTAYEAPSLDARQDIVVVEIPKLGKEAAQKAIKEWGQPKSKITHVIFCTTSGVDMPGADYQITKLLGLRPSVKRFMMYQQGCFAGGTVLRMAKDLAENNAGARVLVVCSEITAITFRGPSDTHLDSLVGQALFGDGAGAVIVGSDPIVGVERPLFQLVSAAQTILPDSEGAIDGHVREVGLTFHLLKDVPGLISKNIEKSLKEAFAPLGISDWNSLFWIVHPGGPAILDQVEEKLGLKPEIMVPTRHVLSEYGNMSSACVLFVMDEMRKASAKDGCTTTGEGKDWGVLFGFGPGLTVETVVLHSVPLN
>Sb09t03120.mRNA1
MVTVEEFHRATRAEGPATVLAIGTANPPNCVEQSTYADYYFRICKSEHLTDLKKKFSRMCEKSGIKKRYMHLTEEFLKENDNFTAYEAPSLDARQDIVVVEIPKLGKEAAQKAIKEWGQPKSKITHVIFCTTSGVDMPGADYQITKLLGLRPSVKRFMMYQQGCFAGGTVLRMAKDLAENNAGARVLVVCSEITAITFRGPSDTHLDSLVGQALFGDGAGAVIVGSDPIVGVERPLFQLVSAAQTILPDSEGAIDGHVREVGLTFHLLKDVPGLISKNIEKSLKEAFAPLGISDWNSLFWIVHPGGPAILDQVEEKLGLKPEIMVPTRHVLSEYGNMSSACVLFVMDEMRKASAKDGCTTTGEGKDWGVLFGFGPGLTVETVVLHSVPLN
>Sb09t03070.mRNA1
MVTVEEFHRATRAEGPATVLAIGTANPPNCVEQSTYADYYFRICKSEHLTDLKKKFSRMCEKSGIKKRYMHLTEEFLKENDNFTAYEAPSLDARQDIVVVEIPKLGKEAAQKSFESNFKLLKLDICD
>Sb09t04060.mRNA1
MVTVEEFHRATRAEGPATVLAIGTANPPNCVEQSTYADYYFRICKSEHLTDLKKKFDRMCEKSCIKKRYMHLTEEFLKENDNFTAYEAPSLDARQDIVVVEIPKLGKEAAQKAIKEWGQPKSKITHVIFCTTSGVDMPGADYQITKLLGLRPSVKRFMMYQQGCFAGGTVLRMAKDLAENNAGARVLVVCSEITAITFRGPSDTHLDSLVGQALFGDGAAAVIVGSDPIVGVERPLFQLVSAAQTILPDSEGAIDGHVREVGLTFHLLKDVPGLISKNIEKSLKEAFAPLGISDWNSLFWIVHPGGPAILDQVEEKLGLKPEIMVPTRHVLSEYGNMSSACVLFVMDEMRKASAKDGCTTTGEGKDWGVLFGFGPGLTVETVVLHSVPLN
>Sb09t03210.mRNA1
MVTVEEFHRATRAEGPATVLAIGTANPPNCVEQSTYADYYFRICKSEHLTDLKKKFSRMCEKSGIKKRYMHLTEEFLKENDNFTAYEAPSLDARQDIVTRKA
>Sb09t03180.mRNA1
MVTVEEFHRATRAEGPATVLAIGTANPPNCVEQSTYADYYFRICKSEHLTDLKKKFSRMCEKSGIKKRYMHLTEEFLKENDNFTAYEAPSLDARQDIVSFESNFKLLKLDICD
>Sb09t03140.mRNA1
MVTVEEYHRATRAEGPATVLAIGTANPPNCIDQSTYADYYFRICKSEHLTELKKKFQRMCDKSYIKKRYMHLTEEFLNENDNMTAFEAPSLDARQDIVVVEIPKLGKEAAQKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRMAKDLAENNAGARVLVVCSEITAVTFRGPSEAHLDSLVGQALFGDGAGAVIVGSDPIVGVERPLFQLVSAAQTILPDSEGAIDGHLREIGLTFHLLKDVPGLISKNIEKSLKEAFAPLDISDWNSLFWIVHPGGPAILDQVEEKLGLKPEIMAQTRQVLSDYGNMSSACVIFVMDEMRKASAKNGCTTTGEGKDWGVLFGFGPGLTVETVVLHSVPLN
MASEESMKNAAILALGKAFPHQLVLQDFLVDAYFRTTNRDDPDLKQKLTRLCKTTSVKTRYVVMSEEILEKYPELAMEGIPTVKQRLDICNSAVTEMAIEASKSCIQKWGGSLSRITHLVYVSSSEARLPGGDLYLAKGLGLRPDTQRVMLYFSGCSGGVAGLRVAKDIAENNPGSRVLVATSETTIIGYRPPSADRPYDLVGVALFGDGAGAMIIGSSPDLATETPLFELHTSLQHFLPDTEKIIDGKLTEEGISFRLDRELPEIIESNIEEFCVELMGFAGFDEKDYNKLFWAVHPGGPAILNKVEKKLELWPEKLSASRRALADYGNASSNTIVYVLEYMLEEAKNGKNGASPWGLILAFGPGITFEGILTRNLTL
>Sb09t03390.mRNA1
MVTVEEFHRATRAEGPATVLAIGTANPPNCVEQSTYADYYFRICKSEHLTDLKKKFSRMCEKSGIKKRYMHLTEEFLKENDNFTAYEAPSLDARQDIVVVEIPKLGKEAAQKAIKEWGQPKSKITHVIFCTTSGVDMPGADYQITKLLGLRPSVKRFMMYQQGCFAGGTVLRMAKDLAENNAGARVLVVCSEITAITFRGPSDTHLDSLVGQALFGDGAGAVIVGSDPIVGVERPLFQLVSAAQTILPDSEGAIDGHVREVGLTFHLLKDVPGLISKNIEKSLKEAFAPLGISDWNSLFWIVHPGGPAILDQVEEKLGLKPEIMVPTRHVLSEYGNMSSACVLFVMDEMRKASAKDGCTTTGEGKDWGVLFGFGPGLTVETVVLHSVPLN
>Sb09t03120.mRNA1
MVTVEEFHRATRAEGPATVLAIGTANPPNCVEQSTYADYYFRICKSEHLTDLKKKFSRMCEKSGIKKRYMHLTEEFLKENDNFTAYEAPSLDARQDIVVVEIPKLGKEAAQKAIKEWGQPKSKITHVIFCTTSGVDMPGADYQITKLLGLRPSVKRFMMYQQGCFAGGTVLRMAKDLAENNAGARVLVVCSEITAITFRGPSDTHLDSLVGQALFGDGAGAVIVGSDPIVGVERPLFQLVSAAQTILPDSEGAIDGHVREVGLTFHLLKDVPGLISKNIEKSLKEAFAPLGISDWNSLFWIVHPGGPAILDQVEEKLGLKPEIMVPTRHVLSEYGNMSSACVLFVMDEMRKASAKDGCTTTGEGKDWGVLFGFGPGLTVETVVLHSVPLN
>Sb09t03070.mRNA1
MVTVEEFHRATRAEGPATVLAIGTANPPNCVEQSTYADYYFRICKSEHLTDLKKKFSRMCEKSGIKKRYMHLTEEFLKENDNFTAYEAPSLDARQDIVVVEIPKLGKEAAQKSFESNFKLLKLDICD
>Sb09t04060.mRNA1
MVTVEEFHRATRAEGPATVLAIGTANPPNCVEQSTYADYYFRICKSEHLTDLKKKFDRMCEKSCIKKRYMHLTEEFLKENDNFTAYEAPSLDARQDIVVVEIPKLGKEAAQKAIKEWGQPKSKITHVIFCTTSGVDMPGADYQITKLLGLRPSVKRFMMYQQGCFAGGTVLRMAKDLAENNAGARVLVVCSEITAITFRGPSDTHLDSLVGQALFGDGAAAVIVGSDPIVGVERPLFQLVSAAQTILPDSEGAIDGHVREVGLTFHLLKDVPGLISKNIEKSLKEAFAPLGISDWNSLFWIVHPGGPAILDQVEEKLGLKPEIMVPTRHVLSEYGNMSSACVLFVMDEMRKASAKDGCTTTGEGKDWGVLFGFGPGLTVETVVLHSVPLN
>Sb09t03210.mRNA1
MVTVEEFHRATRAEGPATVLAIGTANPPNCVEQSTYADYYFRICKSEHLTDLKKKFSRMCEKSGIKKRYMHLTEEFLKENDNFTAYEAPSLDARQDIVTRKA
>Sb09t03180.mRNA1
MVTVEEFHRATRAEGPATVLAIGTANPPNCVEQSTYADYYFRICKSEHLTDLKKKFSRMCEKSGIKKRYMHLTEEFLKENDNFTAYEAPSLDARQDIVSFESNFKLLKLDICD
>Sb09t03140.mRNA1
MVTVEEYHRATRAEGPATVLAIGTANPPNCIDQSTYADYYFRICKSEHLTELKKKFQRMCDKSYIKKRYMHLTEEFLNENDNMTAFEAPSLDARQDIVVVEIPKLGKEAAQKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRMAKDLAENNAGARVLVVCSEITAVTFRGPSEAHLDSLVGQALFGDGAGAVIVGSDPIVGVERPLFQLVSAAQTILPDSEGAIDGHLREIGLTFHLLKDVPGLISKNIEKSLKEAFAPLDISDWNSLFWIVHPGGPAILDQVEEKLGLKPEIMAQTRQVLSDYGNMSSACVIFVMDEMRKASAKNGCTTTGEGKDWGVLFGFGPGLTVETVVLHSVPLN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University