Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Sapindus mukorossi
Species name
Chinese soapberry (Sapindus mukorossi) is a species of eudicot in the family Sapindaceae (soapberry family).
Species info
Gene sequence info
Sapindus_mukorossi.CHS.fa
Download
>whz_010073-RA
MQQQSIASAERIQEPRRSQGLASILAIATVNPANCIHQTDYPDFYFRVTNSDKSTIKKHYMYLTEEILKENPSIGTYNAPTLDARQDILVAEVPKLGKEAASKAIKEWGQPISKITHLIFCSVSSVDMPGADFQLMKLPALKPSVNRVMLYAQGCSAVGTFRGPTHENLSCLVNRAIAGDGAAALIIGANPDLSVEQSMFQIVTATQTTLPDSEYAIKGHFREVGIGNDWNSLFWMIHPIGPVVLNQIEQKPGLEKEKFRATRNVLCEYGNMASATLLFVLDEMRKKSMEEGKTTTGEGLEWGVLLGFGAGIVQLTVTTNLARSLLRSVANDMFRLKYMGVLYGTKLKRVPSW
>whz_010882-RA
MESLVLTSSIHVHNVFHFPENLNHPFDEPPYVIVFVLLAVLNHLPDMKAICSAILNHFLLCRGLCSLWSWHSSGPSRRSPMPGKATVLAIGKAFPHQLIPQECLVEGYIRDTKCEDVSIKEKLERLCKTTTVKTRYTVMSKEILDRYPELATEGSPTIKQRLEIANSAVVEMALEASLACIKEWGRAVEDITHIVYVSSSEIRLPGGDLYLASQLGLKNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVMIGANPLMDKESPFMELNHAVQQFLPGTQHVIDGCLSEEGINFKLGRDLPQKIEDNIEVFCKKLMEKAGLKEFNDLFWAVHPGGPAILNRLESNLRLKSEKLECSRRALMDYGNVSSNTIFYVMDYMRQELKKKDMEEWGLALAFGPGITFEGILLRSL
>whz_009143-RA
MSAEQTIIPDSEEIIEGNMREIGLTMHLSKNPGASAILDQIEEKARLKPEKLWGSRRVIRDQTLNHQPFTRMERQPMPAEGKIRWSAASLAAGYEGGDLVQIQILKEEDEGGA
>whz_009061-RA
MSAEQTIIPDSEEIIEGNMREIGLTIHLSKNVPMMASENIEKCLFEAFHPVGITDWNSLFGWCSRVPQQFSIRLKRKLG
>whz_009087-RA
MREIGLTMHLSKNVPMMASENIEKCLFEAFHLVGITDWNSLFGWCSRHKHTDLVFGEQEVEMVNEPSRKFSQCGQYGHFLRTCPDGGKSHVKLFGVIISNNGQDGSIKSSTIMENLQSIMEPNNVNVNVKVHDENLSNGQVRSKKGKVTHARRKFGLEKLGKGQWKTISRVYVKTRTASQDASHAHKYFLKQASSDKRHRRSSLFDITHTESFSTCQYSPLVKTTTSTSSQANTLLAAMPSKNSYESPTHRRTYVHMPRTIGNITTYSNIITHPSGVSSPHVSSSGEFHPKKVVGKDSLELEVGPP
>whz_009141-RA
MSAEQTIIPDSKEIIEGNMREIGLTMHLSKNVPMMASENIEKCLFEAFHPVGITADASGGDDTVVSGLLSGAGYEGGDLVQIQILKEEDEGGA
>whz_009071-RA
MREIGLTMHLSKNVPMMASENIEKCLFEAFHPVGITDWNSLFGWCSRVPQQFSTRLKRKLG
>whz_009068-RA
MSAEQTIIPDSEEIIEGNMREIGLTMHLSKNVPMMASENIEKCLFEAFHPIGITDWNSLFGWCSRHKYTDLVFGEQEVEMVNEPSRKFSQCGQYGHFLRTCPHGGKSHVKLFGVIISNNGQDGSIKSSTIMENLQSVVEPNNVNVNVKVHDENLSNGQVRSKKGKVVHARRKSGQPWTEEEHKIFLVDLEKLGKGQWKTISRVYVKTRTASQDASHAHKYFLKQASSDKRHRRSSLFDITHTESFSTCQYSPLVKTTTSTSSQANTLLATMPSKNSYESPTQFRASDNDQSLLLTTNVPTLSYFQPMNDQRRTYVHMPRTIGNITTCSNIITYPSGVSSPHVSSSGEFHPKKVVGKDSLELEVRPP
>whz_013797-RA
MSAEQTIIPNSEEIIEGNMREIGLTMHLSKNVPMMASENIEKCLFEAFHPVGITDWNSLFGWCSRTADASRGEDTVVSGLLGGAGYEGGDLVQIQISKEEDGGGA
>whz_013799-RA
MSAEQTIIPDSKEIIEGNMREIGLTMHLSKNVPMMAFENIEKCLFEAFHPVGITDWNSLFGWCSRTADASGGDDTVVSGLLGGAGYKGGDLVQIQILKEEDEGGA
>whz_024799-RA
MGSEYIAPGDFTKKGNPGKATILALGKAFPHQLVMQEFLVDGYFRNTNCDDPELRRKLTRLCQTTTVKTRYVVMSEEILNKYPELAVEGLPTVKQRLDICNAAVTQMAIEASQACIKTWGRPKSDITHLVYVSSSEARLPGGDLYLARGLGLSPETRRVMLYFSGCSGGVAGLRVAKDIAENNPGSRILLATSETTIIGFKPPSPDRPYDLVGVALFGDGAGAMVIGSDPVTFTEKPLFELHTAIQNFLPNTEKTIDGRLTEEGISFKLERELPQIIEDNIEGFCNKLMKVVGMKNQDYNKMFWAVHPGGPAILNRMEKRLDLLPEKLNASRRALMDYGNASSNTIVYVLDYMIEESLKMEKANQSDSEWGLILAFGPGITFEGILARNLTV
>whz_000890-RA
MVTVEEVRRAQRAQGPATILAIGTATPPNCVDQSEYPDYYFRITNSEHKTELKEKFKRMCDKSMIKKRYMYLTEEILKENPHVCAYEAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIIGSDPLPEVEKPMYELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFKPLGISDWNSLFWIAHPGGPAILDQVEIKLGLKPEKLRATRHVLSEYGNMSSACVLFILDEMRKKSAEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVAAA
>whz_000893-RA
MIKKRYTEEMLKEKLDVCEYMEPSLDTRQDILIQERYMLYHQGCFAGDTVLCLAKDVAGNNKDAGYFVCSKIPAVTFLGPDEPHFDNLLGQALFGDGATAVIVGADPFLGLQKPLFELYLRPKKYYPIVMDLLKVI
>whz_000891-RA
MATFNEVRRAQRAQGPAMILAIGTATPPKFVDQSTYADYYFRVTNHEHKTELKKKFKRICEKSMIKKRYMYLTEETLKENPNICAYEAPSLDARQAIVVVEVPKLGKEAATKAIKEWGQPKSNITHLIFCTNSGVDSPGADYQFAKLFGLNPSVNRFMIYHQGCFAGGTAIRLAKDLAENNKGARVLVVCSEVTAILFRGPCDNLDSLIAQALFGDGAAAIIVGSDPMPGVEKPVYEIVSATQTIVSNSDGAIQGPISEVGLKVRIHKDVPLHFSNSIEEILVEAFRPLGISDWNSIFWIAHPGGPAILNQVEAKLGLKPEKLRASRQVLSEYGNLQSACVLFILDEMRKKSAEDGLKTTGEGLQWGVLFGFGPGLTVETVVLQSLATD
MQQQSIASAERIQEPRRSQGLASILAIATVNPANCIHQTDYPDFYFRVTNSDKSTIKKHYMYLTEEILKENPSIGTYNAPTLDARQDILVAEVPKLGKEAASKAIKEWGQPISKITHLIFCSVSSVDMPGADFQLMKLPALKPSVNRVMLYAQGCSAVGTFRGPTHENLSCLVNRAIAGDGAAALIIGANPDLSVEQSMFQIVTATQTTLPDSEYAIKGHFREVGIGNDWNSLFWMIHPIGPVVLNQIEQKPGLEKEKFRATRNVLCEYGNMASATLLFVLDEMRKKSMEEGKTTTGEGLEWGVLLGFGAGIVQLTVTTNLARSLLRSVANDMFRLKYMGVLYGTKLKRVPSW
>whz_010882-RA
MESLVLTSSIHVHNVFHFPENLNHPFDEPPYVIVFVLLAVLNHLPDMKAICSAILNHFLLCRGLCSLWSWHSSGPSRRSPMPGKATVLAIGKAFPHQLIPQECLVEGYIRDTKCEDVSIKEKLERLCKTTTVKTRYTVMSKEILDRYPELATEGSPTIKQRLEIANSAVVEMALEASLACIKEWGRAVEDITHIVYVSSSEIRLPGGDLYLASQLGLKNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVMIGANPLMDKESPFMELNHAVQQFLPGTQHVIDGCLSEEGINFKLGRDLPQKIEDNIEVFCKKLMEKAGLKEFNDLFWAVHPGGPAILNRLESNLRLKSEKLECSRRALMDYGNVSSNTIFYVMDYMRQELKKKDMEEWGLALAFGPGITFEGILLRSL
>whz_009143-RA
MSAEQTIIPDSEEIIEGNMREIGLTMHLSKNPGASAILDQIEEKARLKPEKLWGSRRVIRDQTLNHQPFTRMERQPMPAEGKIRWSAASLAAGYEGGDLVQIQILKEEDEGGA
>whz_009061-RA
MSAEQTIIPDSEEIIEGNMREIGLTIHLSKNVPMMASENIEKCLFEAFHPVGITDWNSLFGWCSRVPQQFSIRLKRKLG
>whz_009087-RA
MREIGLTMHLSKNVPMMASENIEKCLFEAFHLVGITDWNSLFGWCSRHKHTDLVFGEQEVEMVNEPSRKFSQCGQYGHFLRTCPDGGKSHVKLFGVIISNNGQDGSIKSSTIMENLQSIMEPNNVNVNVKVHDENLSNGQVRSKKGKVTHARRKFGLEKLGKGQWKTISRVYVKTRTASQDASHAHKYFLKQASSDKRHRRSSLFDITHTESFSTCQYSPLVKTTTSTSSQANTLLAAMPSKNSYESPTHRRTYVHMPRTIGNITTYSNIITHPSGVSSPHVSSSGEFHPKKVVGKDSLELEVGPP
>whz_009141-RA
MSAEQTIIPDSKEIIEGNMREIGLTMHLSKNVPMMASENIEKCLFEAFHPVGITADASGGDDTVVSGLLSGAGYEGGDLVQIQILKEEDEGGA
>whz_009071-RA
MREIGLTMHLSKNVPMMASENIEKCLFEAFHPVGITDWNSLFGWCSRVPQQFSTRLKRKLG
>whz_009068-RA
MSAEQTIIPDSEEIIEGNMREIGLTMHLSKNVPMMASENIEKCLFEAFHPIGITDWNSLFGWCSRHKYTDLVFGEQEVEMVNEPSRKFSQCGQYGHFLRTCPHGGKSHVKLFGVIISNNGQDGSIKSSTIMENLQSVVEPNNVNVNVKVHDENLSNGQVRSKKGKVVHARRKSGQPWTEEEHKIFLVDLEKLGKGQWKTISRVYVKTRTASQDASHAHKYFLKQASSDKRHRRSSLFDITHTESFSTCQYSPLVKTTTSTSSQANTLLATMPSKNSYESPTQFRASDNDQSLLLTTNVPTLSYFQPMNDQRRTYVHMPRTIGNITTCSNIITYPSGVSSPHVSSSGEFHPKKVVGKDSLELEVRPP
>whz_013797-RA
MSAEQTIIPNSEEIIEGNMREIGLTMHLSKNVPMMASENIEKCLFEAFHPVGITDWNSLFGWCSRTADASRGEDTVVSGLLGGAGYEGGDLVQIQISKEEDGGGA
>whz_013799-RA
MSAEQTIIPDSKEIIEGNMREIGLTMHLSKNVPMMAFENIEKCLFEAFHPVGITDWNSLFGWCSRTADASGGDDTVVSGLLGGAGYKGGDLVQIQILKEEDEGGA
>whz_024799-RA
MGSEYIAPGDFTKKGNPGKATILALGKAFPHQLVMQEFLVDGYFRNTNCDDPELRRKLTRLCQTTTVKTRYVVMSEEILNKYPELAVEGLPTVKQRLDICNAAVTQMAIEASQACIKTWGRPKSDITHLVYVSSSEARLPGGDLYLARGLGLSPETRRVMLYFSGCSGGVAGLRVAKDIAENNPGSRILLATSETTIIGFKPPSPDRPYDLVGVALFGDGAGAMVIGSDPVTFTEKPLFELHTAIQNFLPNTEKTIDGRLTEEGISFKLERELPQIIEDNIEGFCNKLMKVVGMKNQDYNKMFWAVHPGGPAILNRMEKRLDLLPEKLNASRRALMDYGNASSNTIVYVLDYMIEESLKMEKANQSDSEWGLILAFGPGITFEGILARNLTV
>whz_000890-RA
MVTVEEVRRAQRAQGPATILAIGTATPPNCVDQSEYPDYYFRITNSEHKTELKEKFKRMCDKSMIKKRYMYLTEEILKENPHVCAYEAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIIGSDPLPEVEKPMYELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFKPLGISDWNSLFWIAHPGGPAILDQVEIKLGLKPEKLRATRHVLSEYGNMSSACVLFILDEMRKKSAEDGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVAAA
>whz_000893-RA
MIKKRYTEEMLKEKLDVCEYMEPSLDTRQDILIQERYMLYHQGCFAGDTVLCLAKDVAGNNKDAGYFVCSKIPAVTFLGPDEPHFDNLLGQALFGDGATAVIVGADPFLGLQKPLFELYLRPKKYYPIVMDLLKVI
>whz_000891-RA
MATFNEVRRAQRAQGPAMILAIGTATPPKFVDQSTYADYYFRVTNHEHKTELKKKFKRICEKSMIKKRYMYLTEETLKENPNICAYEAPSLDARQAIVVVEVPKLGKEAATKAIKEWGQPKSNITHLIFCTNSGVDSPGADYQFAKLFGLNPSVNRFMIYHQGCFAGGTAIRLAKDLAENNKGARVLVVCSEVTAILFRGPCDNLDSLIAQALFGDGAAAIIVGSDPMPGVEKPVYEIVSATQTIVSNSDGAIQGPISEVGLKVRIHKDVPLHFSNSIEEILVEAFRPLGISDWNSIFWIAHPGGPAILNQVEAKLGLKPEKLRASRQVLSEYGNLQSACVLFILDEMRKKSAEDGLKTTGEGLQWGVLFGFGPGLTVETVVLQSLATD
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University