Enzyme
A cytochrome P-450 (heme-thiolate) protein found in plants. The enzyme is involved in flavonoid biosynthesis.
C4H
Enzyme
Cinnamate 4-hydroxylase
Enzyme name
EC:1.14.14.91
Entry
Oxidoreductases;Acting on paired donors, with incorporation or reduction of molecular oxygen;With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
Class
trans-cinnamate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating)
Sysname
trans-cinnamate + [reduced NADPH---hemoprotein reductase] + O2 = 4-hydroxycinnamate + [oxidized NADPH---hemoprotein reductase] + H2O[RN:R02253]
Reaction
4-hydroxycinnamate [CPD:C00811];[oxidized NADPH---hemoprotein reductase] [CPD:C03161];H2O [CPD:C00001]
Product
Species information
Salvinia cucullata
Species name
Salvinia cucullata is a species of fern in the family Salviniaceae.
Species info
Gene sequence info
Salvinia_cucullata.C4H.fa
Download
>Sacu_v1.1_s0001.g000050
MALLDLGYSLSFESLLYSLLAIVLAGLAVLHFLKPKLRLPPGPVAVPVFGNWLQVGDDLNHLNLSEMASKYGEIFLLRMGQRNLVVISSPELAKEVLHTQGVEFGSRTRNVVFDIFTGNGQDMVFTVYGDHWRKMRRIMTVPFFTSKVVQQSRDFWAEEVDSAIADLKANPAASTTGVVIRRRLQMLMYNNMYRMMFHRRFEREDDPLFVELKRLNGERSRLAQSFEYNYGDFIPILRPFLRKYLRTCQKFRLPPGPVAVPIFGNWLQVGDDLNHINLSAMARKYGEIFLLRMGQRNLVVISSPELAKEVLHTQGVEFGSRTRNIVLDIFTGKGQDMAFTVYGDHWRKMRRIMTVPFFTNKVVQQSKDFWAEEVESAIADLKANPAASTDGVIIRRRLQMLMYNNMYRMMFNRRFEREDDPLYVELKRLNGERSRLSQSFEYNFGDFIPILRPFLRKYLLTCQKVKDQRLKLFKDYFLDER
>Sacu_v1.1_s0001.g000234
MALPAVVASALDLLPPLGLETILFSLLFVSLASIAFFQLRRPSLRLPPGPFSFPIFGNWLQVGDDLNHLNLSEMARKYGEIFLLRMGQRNLVVVSSPELAKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVQQSRVFWEEEVDSAIADLKANPAASTTGVVIRRRLQMLMYNNMYRMMFGRRFEREDDPLFVELKRLNGERSRLAQSFDYNYGDFIPILRPFLKKYLELCKKVKQERLQLFKDYFLDERK
>Sacu_v1.1_s0003.g001860
MAILDLVFPYRLFKIFLPSSVFPSRLFKILPYDESALEIAGPWKNLRLILVMVGFLSVVILRLRRGFLKLPPGPPRFPFVGNWLQVGDGLDHKKLGSLATKYGDIFFLKMGARKIVVVSSSALAKEVLHVKGVEFASRKGNLVYDIFTGKGQDLVYTMYGDSWRRMRRIMTVPFCTNKVVQESRAAWEEEINMAVNDVILDRESFTSGIVLWKRLQLIVYNVIYRMMFDRRFSDENDPLYVELVAYNTERSRLAHSFDYNYVDFMPIFKPFLKGYLKQCQDVQDRQLAFFRESFVEERRKRLAAAEGTDCIRKCAIDRILRDQMNNEIKENNILYLIESINVQAIETILCSMEWVIAEIINHQEVQDRLRDELDAVLGEATLTEPDINKLPYLRAVVKESLRLHMPIPLLMPHMNLKEEKLGNYDIPAGTKVLVNAWWIANNPETWVDPEKFLPDRFMNESIEPNGTDFRFLPFGSGRRCCPGSILALPLLALVVGRLVQTYELLPGHGSDAIDMAELERQSRLQLLNHSLVRVRVHLCGDCSSQCSLRLPFLLPDQSFGMKSYVAQVDIEKDTGQKPVNFNQSKNANFLIFRSLFLVNFKDELLQGLLDRQQFRELILEFGGVQFIVAAGSYDDLCLFFESEVGPLEVRIDVIPVHLQDFIVAHHTRICEIPDACEVPFRHLNRNGQHLIQHSHAVGDVDHLLVPGNFGDEIPGIGKIRRDGHADSQSADIVIILEEILHLRRGRTNKRT
>Sacu_v1.1_s0032.g010827
RPQFQFVPLIQSKQSVHPSLDPSISPTTMNTENWLLLVATLLAATIAATAWLRSRRLRLPPGPWPLPVLGNWLQVGDDLNHRLLAGFARRYGDIFLLRMGQRNLVVVSSPELAKEVLHTQGVEFGSRTRNVVFDIFTGNGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVQQNRRCWESEIDSVISDVKSDAASTTSGVVLRHRLQLFMYNVMFGMLFHHRFPSLTDPLFLQLRQLNNERSRLAQSFDYNYGDFIPVLRPFLRRYLRRCQEVKDRRLGLFDEAFVKPRKAMIKERGGALLNNEEKCALDHILEARDRGEINDANVLYIIENINVAAVETTLWSMEWGIAEMVNHPEMQQKVREEMEAVLGKGVPLTEPEVGKLPYLQAVVKETLRLHMAIPLLVPHMNLKQGKLGGYDIPAESKILVNAWWLANNPDLWENPDVFRPERFLEECKGAEANGNEFRYIPFGVGRRSCPGIILALPLLAMVIGRLIQAFQLLPRPGEMGVDMSEKGGQFSLHLLHHSRIRLQPL
>Sacu_v1.1_s0039.g012203
MAALSDLLPPSLSSLSLETILFSLFLVVFLALLIHYILKPKLRLPPGPVAVPIFGNWLQVGDDLNHLNLSEMACKYGEIFLLRMGQRNLVVISSPELAKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVQQSRVFWEEEVDFAIADIKANPASATTGVVIRKRLQMLMYNNMYRMMFNRRFEREDDPLFVELKRLNGERSRLAQSFEYNYGDFIPILRPFLSGYLNLCKKVKEERLKLFKDYFLDERKKLTSVKPPSNDEKCAIDHILDAQKNGEINEDNVLYIIENINVAAIETTLWSVEWGIAELVNNPHLQKKVREEMDAVLGHGNLITESDIPKLPYLHAFIKETLRLHMAIPLLVPHMNLHQAKLAGYDIPAESKILVNAWYLANNPEWWDKPEEFRPERFLGEEKIEANGNDFRFLPFGVGRRSCPGIILAIPILSIVLGRLVQSFELLPPPGADKVDVTGKGGQFSLHIQTHSTVVCKPLL
>Sacu_v1.1_s0066.g016178
MALFLDLSFSSFLNASLFSVLGLLLLLNLFQRLRLKLPPGPFPWPIVGNWLQFRNGLTPQNLAELAKKYGDVCLLQMGQRNVLVISSPEMAKEVLVTQGAEFGSRARNLVFDMTTGKGQDMVFADYGDHWRKMRRIATLPFFTNKVVQQNRHGWEEEVNLAIKDIRNSPGATTSGIIIRERLQLMMYNIVYRMMFGRTFSGLEDPLYVQLMTLNNENNRLAQSFKYSYGDFVPSLKPFLRGYLQEVWKTNQRRLAFLRDAFLNERKKATGDRIGVDHFLEAQKKGEISENSVLYLIQNMNVAAIETTLWSTEWGIAEMINNPQIQEKLRNELDTVLGKGVPLTEPDVAKLPYLQALVKEILRMHMVIPMLVPHMNIQAAKLGGFDIPAGCRVLVNAWGIANNPKYWDKPEVFNPDRFLDSKMEATGNDMRFIPFGVGRRSCPGSIIALPILGLVLGRIVQEFELLPPPGFNKVDLRGVGGQLSLSIAVKSRVLVKPRNF
>Sacu_v1.1_s0159.g023841
MAAHALDSTSIPSPLSFLASLVAATLVLVLLFKSVLQRWRTKLPPGPWAWPVVGSWPQFRNGLTPQNLAELADKYGDVCLLRMGQRKVVVVSSPEMAKEVLVTQGAEFGSRARNLVFDMTTGKGQDMVFADYGDHWRKMRRIATLPFFTHKVVQQHRHGWEQEIDLAMADIRLNPQASSSGIVVRNRLQLMMYNIVYRMMFGRTFAGLDDPLYVELMTLNDENNRLAQSFKYNYGDFIPSFKPLLNSYLKEVWDTNQRRLAFLRDAFLNERRKAKGDKIGVDHFLEAHMKGEISENSVLYLIQNMNVAAIETTLWSTEWGIAEMVNNPRIQEKLRQEMDSVLGKGVPVTEPEVAKLPYLQSLVKEILRMHMVIPMLVPHMNLQAAKLGDYDIPAGSRILVNAWGIANNPKYWDKPEVFNPDRFLDSKIEATGNDLKFIPFGVGRRSCPGSIIALPILALVLGRLVQEFDLLPPPGAQNVDLRGVGGQLGLRIAIKSNVVLKPR
MALLDLGYSLSFESLLYSLLAIVLAGLAVLHFLKPKLRLPPGPVAVPVFGNWLQVGDDLNHLNLSEMASKYGEIFLLRMGQRNLVVISSPELAKEVLHTQGVEFGSRTRNVVFDIFTGNGQDMVFTVYGDHWRKMRRIMTVPFFTSKVVQQSRDFWAEEVDSAIADLKANPAASTTGVVIRRRLQMLMYNNMYRMMFHRRFEREDDPLFVELKRLNGERSRLAQSFEYNYGDFIPILRPFLRKYLRTCQKFRLPPGPVAVPIFGNWLQVGDDLNHINLSAMARKYGEIFLLRMGQRNLVVISSPELAKEVLHTQGVEFGSRTRNIVLDIFTGKGQDMAFTVYGDHWRKMRRIMTVPFFTNKVVQQSKDFWAEEVESAIADLKANPAASTDGVIIRRRLQMLMYNNMYRMMFNRRFEREDDPLYVELKRLNGERSRLSQSFEYNFGDFIPILRPFLRKYLLTCQKVKDQRLKLFKDYFLDER
>Sacu_v1.1_s0001.g000234
MALPAVVASALDLLPPLGLETILFSLLFVSLASIAFFQLRRPSLRLPPGPFSFPIFGNWLQVGDDLNHLNLSEMARKYGEIFLLRMGQRNLVVVSSPELAKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVQQSRVFWEEEVDSAIADLKANPAASTTGVVIRRRLQMLMYNNMYRMMFGRRFEREDDPLFVELKRLNGERSRLAQSFDYNYGDFIPILRPFLKKYLELCKKVKQERLQLFKDYFLDERK
>Sacu_v1.1_s0003.g001860
MAILDLVFPYRLFKIFLPSSVFPSRLFKILPYDESALEIAGPWKNLRLILVMVGFLSVVILRLRRGFLKLPPGPPRFPFVGNWLQVGDGLDHKKLGSLATKYGDIFFLKMGARKIVVVSSSALAKEVLHVKGVEFASRKGNLVYDIFTGKGQDLVYTMYGDSWRRMRRIMTVPFCTNKVVQESRAAWEEEINMAVNDVILDRESFTSGIVLWKRLQLIVYNVIYRMMFDRRFSDENDPLYVELVAYNTERSRLAHSFDYNYVDFMPIFKPFLKGYLKQCQDVQDRQLAFFRESFVEERRKRLAAAEGTDCIRKCAIDRILRDQMNNEIKENNILYLIESINVQAIETILCSMEWVIAEIINHQEVQDRLRDELDAVLGEATLTEPDINKLPYLRAVVKESLRLHMPIPLLMPHMNLKEEKLGNYDIPAGTKVLVNAWWIANNPETWVDPEKFLPDRFMNESIEPNGTDFRFLPFGSGRRCCPGSILALPLLALVVGRLVQTYELLPGHGSDAIDMAELERQSRLQLLNHSLVRVRVHLCGDCSSQCSLRLPFLLPDQSFGMKSYVAQVDIEKDTGQKPVNFNQSKNANFLIFRSLFLVNFKDELLQGLLDRQQFRELILEFGGVQFIVAAGSYDDLCLFFESEVGPLEVRIDVIPVHLQDFIVAHHTRICEIPDACEVPFRHLNRNGQHLIQHSHAVGDVDHLLVPGNFGDEIPGIGKIRRDGHADSQSADIVIILEEILHLRRGRTNKRT
>Sacu_v1.1_s0032.g010827
RPQFQFVPLIQSKQSVHPSLDPSISPTTMNTENWLLLVATLLAATIAATAWLRSRRLRLPPGPWPLPVLGNWLQVGDDLNHRLLAGFARRYGDIFLLRMGQRNLVVVSSPELAKEVLHTQGVEFGSRTRNVVFDIFTGNGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVQQNRRCWESEIDSVISDVKSDAASTTSGVVLRHRLQLFMYNVMFGMLFHHRFPSLTDPLFLQLRQLNNERSRLAQSFDYNYGDFIPVLRPFLRRYLRRCQEVKDRRLGLFDEAFVKPRKAMIKERGGALLNNEEKCALDHILEARDRGEINDANVLYIIENINVAAVETTLWSMEWGIAEMVNHPEMQQKVREEMEAVLGKGVPLTEPEVGKLPYLQAVVKETLRLHMAIPLLVPHMNLKQGKLGGYDIPAESKILVNAWWLANNPDLWENPDVFRPERFLEECKGAEANGNEFRYIPFGVGRRSCPGIILALPLLAMVIGRLIQAFQLLPRPGEMGVDMSEKGGQFSLHLLHHSRIRLQPL
>Sacu_v1.1_s0039.g012203
MAALSDLLPPSLSSLSLETILFSLFLVVFLALLIHYILKPKLRLPPGPVAVPIFGNWLQVGDDLNHLNLSEMACKYGEIFLLRMGQRNLVVISSPELAKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGDHWRKMRRIMTVPFFTNKVVQQSRVFWEEEVDFAIADIKANPASATTGVVIRKRLQMLMYNNMYRMMFNRRFEREDDPLFVELKRLNGERSRLAQSFEYNYGDFIPILRPFLSGYLNLCKKVKEERLKLFKDYFLDERKKLTSVKPPSNDEKCAIDHILDAQKNGEINEDNVLYIIENINVAAIETTLWSVEWGIAELVNNPHLQKKVREEMDAVLGHGNLITESDIPKLPYLHAFIKETLRLHMAIPLLVPHMNLHQAKLAGYDIPAESKILVNAWYLANNPEWWDKPEEFRPERFLGEEKIEANGNDFRFLPFGVGRRSCPGIILAIPILSIVLGRLVQSFELLPPPGADKVDVTGKGGQFSLHIQTHSTVVCKPLL
>Sacu_v1.1_s0066.g016178
MALFLDLSFSSFLNASLFSVLGLLLLLNLFQRLRLKLPPGPFPWPIVGNWLQFRNGLTPQNLAELAKKYGDVCLLQMGQRNVLVISSPEMAKEVLVTQGAEFGSRARNLVFDMTTGKGQDMVFADYGDHWRKMRRIATLPFFTNKVVQQNRHGWEEEVNLAIKDIRNSPGATTSGIIIRERLQLMMYNIVYRMMFGRTFSGLEDPLYVQLMTLNNENNRLAQSFKYSYGDFVPSLKPFLRGYLQEVWKTNQRRLAFLRDAFLNERKKATGDRIGVDHFLEAQKKGEISENSVLYLIQNMNVAAIETTLWSTEWGIAEMINNPQIQEKLRNELDTVLGKGVPLTEPDVAKLPYLQALVKEILRMHMVIPMLVPHMNIQAAKLGGFDIPAGCRVLVNAWGIANNPKYWDKPEVFNPDRFLDSKMEATGNDMRFIPFGVGRRSCPGSIIALPILGLVLGRIVQEFELLPPPGFNKVDLRGVGGQLSLSIAVKSRVLVKPRNF
>Sacu_v1.1_s0159.g023841
MAAHALDSTSIPSPLSFLASLVAATLVLVLLFKSVLQRWRTKLPPGPWAWPVVGSWPQFRNGLTPQNLAELADKYGDVCLLRMGQRKVVVVSSPEMAKEVLVTQGAEFGSRARNLVFDMTTGKGQDMVFADYGDHWRKMRRIATLPFFTHKVVQQHRHGWEQEIDLAMADIRLNPQASSSGIVVRNRLQLMMYNIVYRMMFGRTFAGLDDPLYVELMTLNDENNRLAQSFKYNYGDFIPSFKPLLNSYLKEVWDTNQRRLAFLRDAFLNERRKAKGDKIGVDHFLEAHMKGEISENSVLYLIQNMNVAAIETTLWSTEWGIAEMVNNPRIQEKLRQEMDSVLGKGVPVTEPEVAKLPYLQSLVKEILRMHMVIPMLVPHMNLQAAKLGDYDIPAGSRILVNAWGIANNPKYWDKPEVFNPDRFLDSKIEATGNDLKFIPFGVGRRSCPGSIIALPILALVLGRLVQEFDLLPPPGAQNVDLRGVGGQLGLRIAIKSNVVLKPR
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University