Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Salvia bowleyana
Species name
Salvia bowleyana is a species of eudicot in the family Lamiaceae (mint family).
Species info
Gene sequence info
Salvia_bowleyana.CHS.fa
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>NDS_001683-RA
MELNVIRGCYGGAAALRAAKDLAENNASARVLVVSSETTTIGFRGPSGAHPENLIGQALFGDAAAALIVGSDPVAGVELSLFQIVSAAQAIIPNSDGAIVGEVREAGLVIHLRPDVPALISGNIGASLEEAFGPLGIRDWDSIFWIAHPGGPKILDRIETGLGLKPEKLRLSRRVLSEYGNVSSATVLLILDEMRRASAEEGLSTTGEGLDWGVLFGFGPGLTVETVVLRSMPIN
>NDS_001681-RA
MATVEEIRRAQRAEGPATVLSIGTAVPPNCVEQSTFPDSYFRVTNSEHMADVKRTFKRM
>NDS_027742-RA
MSTKQQRSPTAGKATILGIGKAFPRQLEILEEYPELAKEGSPTIKQRLDIAHPAVLEMAKEASLACLKDWKREAKDITHVVYVSSSEIRLPGGDLYLATELALRNDVARVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLATSETTILGFRPPNKSRPYDLVGAALFGDGAAAVVVGADPVPGVETAFMELNTAAQQFLPGTSHVIDGRLSEEGIYFKLGRDLPQKIEENIEEFCRKLMGGAAGLGEGGYDYNSLFWAVHPGGPAILNRLESALRLDEGKLECSRKALMDYGNVSSNTIFYVMEYMREELGKKGDKGEEWGLALAFGPGITFEGILLRSLLH
>NDS_061707-RA
MVSAAEIRRAPPAEGPATLLAIGTATPLNCVEQSTFPDYYFRVTNSENSKIKKRYMHLNEDLLRENPSIADYEAPSLNARLEIAMVEAPKLGKIAAEKAIKEWGQPKSNITHLIFCTSTASADLPAVDYRLANLLGLRPTVIRTMLCQQGCYGGGAALRLAKDLAENNAAARVLVVCCELNTICFRGPSEDHVEDLVGQALFGDAAAAVIVGADPAAAERPVFQIMSAAQATVPATDDRIRGRLREAGLLVDLFKDIPGLLSENIGENLERAFGPWGISDWNSIFWIAHPGGPKILDQVEAKAGLKPEKLRMSRHVLSEYGNVSSPSVLLILDEMRKAAAEEGRSTTGEGLEWGVLFGFGPGLTVETVVLQSMPI
>NDS_061886-RA
MASVEEIRRARRAEGPATVLAIGTATPPNCVEQSSFPDYYFRVTNSEHKTELKEKFMRICENSMIKKRYMHLTEDLLKENPNIAAYSAPSLSVRQEMVEVEVPKLGQEAAEKAIKEWGQPNTAATAAPPPSAWPRTWPRTTAAARVLVVCCEITAICFRGPSEAHVGDLVGQALFADGAAAVIVGADPPPAAERPLFQIMSAAQATIPGSDDRIRGRMREAGLLIDLVRDLPDLVSDNVGASLERAFGPWGISEWNSIFWVLHPGGPAILDQVEAKVGLKPEKLRRSRRVLSEYGNMWSPSVLFVLDEMRKFSAEEGRSTTGEGLEWGVLFGFGPGLTVETVVLRSMPIDL
>NDS_061885-RA
MASVEEIHRARRAEGPATVLAIGIATPPNCIEQSTFPDYYFRVTNSEHKTELKEKFKRIYNEILQTSMHIHSIAF
>NDS_070675-RA
MHLTEEILKEKPNMCEEAAPSLDDRQDILVAEVPKLGKSAAEKAIADWGGPISNITHLIFCTSSGIDIPGADLRLAKLLGLCPSVKRLMMYQQGCSGGAAALRMAKDLAENNAGARVLIVCAEIMAMIFRGPSEANLDHLVGQALFGDGASAVIVGSDPVAAVERPVFEVVAAAQAFLPGTEDVVHGQLKEVGIVYRLGRTLAGFISDSIERCLEEVFGPLGFGSPDWNSIFWISHPGGPAILDGIEAKLGLRPEKLRASRRVLCEYGNMMSATVGFVMDEMRKSSAAEGRSSTGEGAEWGVLLGFGWGLTVETLVLRSVPINSD
MELNVIRGCYGGAAALRAAKDLAENNASARVLVVSSETTTIGFRGPSGAHPENLIGQALFGDAAAALIVGSDPVAGVELSLFQIVSAAQAIIPNSDGAIVGEVREAGLVIHLRPDVPALISGNIGASLEEAFGPLGIRDWDSIFWIAHPGGPKILDRIETGLGLKPEKLRLSRRVLSEYGNVSSATVLLILDEMRRASAEEGLSTTGEGLDWGVLFGFGPGLTVETVVLRSMPIN
>NDS_001681-RA
MATVEEIRRAQRAEGPATVLSIGTAVPPNCVEQSTFPDSYFRVTNSEHMADVKRTFKRM
>NDS_027742-RA
MSTKQQRSPTAGKATILGIGKAFPRQLEILEEYPELAKEGSPTIKQRLDIAHPAVLEMAKEASLACLKDWKREAKDITHVVYVSSSEIRLPGGDLYLATELALRNDVARVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLATSETTILGFRPPNKSRPYDLVGAALFGDGAAAVVVGADPVPGVETAFMELNTAAQQFLPGTSHVIDGRLSEEGIYFKLGRDLPQKIEENIEEFCRKLMGGAAGLGEGGYDYNSLFWAVHPGGPAILNRLESALRLDEGKLECSRKALMDYGNVSSNTIFYVMEYMREELGKKGDKGEEWGLALAFGPGITFEGILLRSLLH
>NDS_061707-RA
MVSAAEIRRAPPAEGPATLLAIGTATPLNCVEQSTFPDYYFRVTNSENSKIKKRYMHLNEDLLRENPSIADYEAPSLNARLEIAMVEAPKLGKIAAEKAIKEWGQPKSNITHLIFCTSTASADLPAVDYRLANLLGLRPTVIRTMLCQQGCYGGGAALRLAKDLAENNAAARVLVVCCELNTICFRGPSEDHVEDLVGQALFGDAAAAVIVGADPAAAERPVFQIMSAAQATVPATDDRIRGRLREAGLLVDLFKDIPGLLSENIGENLERAFGPWGISDWNSIFWIAHPGGPKILDQVEAKAGLKPEKLRMSRHVLSEYGNVSSPSVLLILDEMRKAAAEEGRSTTGEGLEWGVLFGFGPGLTVETVVLQSMPI
>NDS_061886-RA
MASVEEIRRARRAEGPATVLAIGTATPPNCVEQSSFPDYYFRVTNSEHKTELKEKFMRICENSMIKKRYMHLTEDLLKENPNIAAYSAPSLSVRQEMVEVEVPKLGQEAAEKAIKEWGQPNTAATAAPPPSAWPRTWPRTTAAARVLVVCCEITAICFRGPSEAHVGDLVGQALFADGAAAVIVGADPPPAAERPLFQIMSAAQATIPGSDDRIRGRMREAGLLIDLVRDLPDLVSDNVGASLERAFGPWGISEWNSIFWVLHPGGPAILDQVEAKVGLKPEKLRRSRRVLSEYGNMWSPSVLFVLDEMRKFSAEEGRSTTGEGLEWGVLFGFGPGLTVETVVLRSMPIDL
>NDS_061885-RA
MASVEEIHRARRAEGPATVLAIGIATPPNCIEQSTFPDYYFRVTNSEHKTELKEKFKRIYNEILQTSMHIHSIAF
>NDS_070675-RA
MHLTEEILKEKPNMCEEAAPSLDDRQDILVAEVPKLGKSAAEKAIADWGGPISNITHLIFCTSSGIDIPGADLRLAKLLGLCPSVKRLMMYQQGCSGGAAALRMAKDLAENNAGARVLIVCAEIMAMIFRGPSEANLDHLVGQALFGDGASAVIVGSDPVAAVERPVFEVVAAAQAFLPGTEDVVHGQLKEVGIVYRLGRTLAGFISDSIERCLEEVFGPLGFGSPDWNSIFWISHPGGPAILDGIEAKLGLRPEKLRASRRVLCEYGNMMSATVGFVMDEMRKSSAAEGRSSTGEGAEWGVLLGFGWGLTVETLVLRSVPINSD
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University