Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Rubus corchorifolius
Species name
Rubus corchorifolius is a species of eudicot in the family Rosaceae (rose family).
Species info
Gene sequence info
Rubus_corchorifolius.COMT.fa
Download
>Rf060218850
MEDVNRTKEASNEARLAIVELANMISVPMSLNAVVRLNVANAIWQSGSNTPLSASQILARVLPAGGGDAENLQRILRMLTSYGVFSEHLNADGSERKFSLTEIGQTLVTNQDGLSYGAYVLQHHQDELMRAWPLVHEAVVDPTVEPFVKANGEPAYQYYGKKPEMNGLMQKSMSGVSVPFMKAILDGCDCFEGVRRLVDVGGSAGDCLRMILDKHPNVTEGINFDLPEVVAKAPTIARVTHVGGDMFKAIPTADAIFMKWVLSTWTDRECKLILENCYKALPVGGKLICCEPMLPKKSDDSHRTRALLENDIFVMTIYRAKGKNRTEEEFRQLGHSVGFSYSRPIYIDYFFTVLEFKK
>Rf060218860
MEDLNQTKEAGNEARLAIVELANMISVPMSLIAVVRLNVADAIWQSGSNNPLSTSEILAHVLPAGSGDAENLQRILRMLTSYGVFSEHLNADGSERKFSLTEIGQTLVTTEDGLSYGAYILQHHQDALMRAWPLVHEVVVDPTVEPFVKANGEPAYQYYGKKPKMNRLMQKAMSGVSVPFMKAILEGYDGFEGVKRLVDVGGSAGDCLRMILDRHPNVTEGINFDLPEVVANAPTIAGVTHVGGDMLKSIPSGDAIFIKWVFSTWTNRECKLILENCYKALPVGGKLIFCEPMLPKKSDDSHRTRALLENDIFLMTMYQAKDTNRTEEEFRQLGYSAGFSHSRSIYIDYFFTVLEFQK
>Rf030105340
MESLGSLESHISARVLANSIAVQMTLRAAIELNVFNIIAKSGRGAHLTSKEIVSQISTTNPNLAVKNLERILRLLSVHSLLTTSQKSDPNDQTTQETSYGLTKETLCFVPNEDGVSCVPLVLWGSEMHCIKSLYMLKYTVLEPESSPFYKAHGEAFYEYMSETPDVSRLFDKVLGLTSYLHFDQKVFEVYRGFQEVKELMDVGGGDGAVIAKIVSVYPHIHGVNFNLPSVIAKAPTYQGVKHVGGDMFESIPSTQSIMLKSVLCDWDDEHCKKILKNCWEALPENGKVIVVEHNVLPEVVENTPEMMPILYCDIYMMALCPGGKERTTAELDNLAKSVGFVETIFFPISHGNYVIEFLKGNVN
>Rf050165680
MENQRISSTNHVSAWCLGSLIPTQMAIKAAIELNVFNIIANAGPGAHLSSKEIVSQISTTNPNAAVENLERILRVLSVHSFLSISQRPSSNSMKMLERTYGLTNASLFLVPNEDGVSLAPNVVLSSEMDIVKSLSMLKDTVLEPGCLPFNKAHGVSIYDHMSGKPELSQLFNKAVGQSSILDFEEVLKIYKGFEEVEELMDVGGGIGTTIQKVVSCYPHIHGINFDLPNVIAQGKAKYPGVKHVGGDMFELIPNVKSIMLKWVLHNWNDDQCKKILKRCWEALPKSGKVIVVEFAIPEILENTFEVIKIVSMDILMMTCPGGRERTIAEFDNLAKSVGFLDTKAFPISHGCYVMEFHKKKHI
>Rf050177800
MDLVEYLGGDARYGEVFKNSMKEFNPILMKEILENYTGFDGLNTLVDVGGADGTILNMIVSKYPTIKGINYDLASVIEKSPSYPGIEHIAGDMFVAIPKGDAIFMKVKLALGFYKQWVLHLYDDKRCLMILKNCYEALPKHGKMIVVNLVIPEAPEISVSAKSLFQFDMFLMNTTTTEKERTDREFESLAKQAGFYTIRVACSAFNFSVVELFKSM
>Rf050154470
MGTQGSLENHISALDIGNSLIIQMTLRAAIELDVFNIIAKSGPGAHLSSKEIVSQIPTTNSISAAMNLERMLNLLSVNSFLSISLRPATENDKTVQEKTYGLTKNALCLVPNEDGVSLAPLILLGSEMFTVQSLCMLKCSVLEPECSPFYKAHGEAYFEYMSKKPEFIQLFEKLMIVRSYLYFDHKVLEVYRGFKELKELTDVGGGDGSSTAKIVSMYPHIHGINFNLSSIIDQAPKYQGVKHVKGDMFKSIPKTQSIMLKEVLHNWDDEDCKQILKNCWEALPKTGKVIVVEYVIMPEVLKNTPEIVHSLAVDIMMMTLFSDDSWIPGIPLSKPSVETADVDMLAGVQELIVHPGTWNEDMIKETFSPIDAEAILANPY
>Rf050154480
MGIQGNLENHISALDIGNSLCVQMTIRAAIELDVFNIIAKSGPGAHLSSKEIVSQIPTTNSISAAKNLERMLNLLSVGSFLSISSRPATSNDNTVQEKTYGLTENALSLVPNEDGVSLTPLMIMNSNMSTVQSLYMLKHSVLEPDCSPFYKAHGEAYFEYMSKKPEFIELFDKVMRLSSSLHFDRKVLQVYRGFQELEELMDVGGGDGSSIAKIVSMYPHIHGTNFNLSSIIDQAPEYQGVKHVKGDMFKSIPKTQTIMLKAVLHNWDDEHCKKILRNCWEALPKSGKVIVVEYFMIPEELQNTPETLNLIAADIVMMTLTSGGKERTAADFDHLAKSVGFVETKVFPISQGTCVIEFLKREI
>Rf020041970
MGTQGSLENHISAFEIGNSLCIQMALRAAIELDVFNIIAKTGPGAHLSSKEFVSQIRTTNPILAARNLERILNLLSVNSLLSTSLRPTLNDETPQEKTYGLTRNALCLVPNEDGVSFAPVLMFCSEMHYVQSLYMLKHTVLEPECSPFYKGYGLTFYEYMSTKPEMIQLFDKAMSITSYMYFDKKVLEVYRGFQELKELMDVGGGDGSSVAKIVSTYPHIHGINFNLPSIIDEAPKYQGVKHVKGDMFESIPKTESIMLKWVLHNWDDNQCKKILKNCWEALPKTGKVIVVEYFVTPGVLENTPETRHTLMSDILMMSLFAGGKERTTAEFDDLAKSVGFIETKCFPISHGTCVIEFLKY
>Rf020059310
MSSTSSEITHTNTMSQQHDEEELGKLAIRLANVVILPMVLKSALELNVIDIIWAAGDGACLSPSDIAAQLPTDNSNAPVVLDRMLRLLASHSILKCSARTGPDGQVERLYGAGPICKFLVKDQNGGTGSVGPLFLLHHEKVFMESWFHLNDAVLEGGIPFNRAYGMTAFEYPETDERFNRVFNQAMSNHTTLILKKILDVYKGFEGINVLVDVGGGIGVTLNLITTKYPHIKGINFDLPHVLADAPSYPGVEHVGGDMFNSVPEGDAIFMKWILHDWSDEHCLTLLKNCCKSIPSSGKVIFVESILPEVPDCSITSNIVCEQDLLMFTQNPGGKERTKKEYEALALKSGFSRMEIVCSAYNSWVMEFHK
>Rf070234460
MFSSVPSGDAIFMKWILHDWSDEHCLKLLKNCYNAIPENGKVIVVEALLPVVPETSTAVKSTSQIDVLMMTQNPGGKERSEQEFIALATAAGFRGIRYECFVCNFWVMEFFK
>Rf070234450
MSMQSAVELGVFDIIAKAGPGAGLSSAKIAAQIGTKNAEAPMMLDRILRLLASHSVLNCTVVNANDGDHGDGPNFQRVYSLAPVSKYFVKSDEDGVSLGALMALIQDKVFLDSWFQLKGAVVEGGIPFNRVHGTHAFEYPGLDPRFNQVFNTAMFNHTTIVIKKILDLYKGFEHLKQLVDVGVALE
>Rf070265470
MGSTGETQMTPTQVSDEEANLFAMQLASASVLPMVLKAAIELDLLEIMAKAGPGAFLSPKDLAAHLPTKNPEAPVMLDRILRLLASYSILTYSLHTLPDGKVERLYGLGPVCKFLTKNEDGVSIAPLCLMNQDKVLIESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNRGMADHSTITMKKILETYKGFEGLTSIVDVGGGTGAVVNMIVSKYPSIKGINFDLPHVIEEAPQYPGVQHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKFLKNCYAALPDDGKVILGECILPVAPDTSLATKGVVHIDVIMLAHNPGGKERTEQEFEALAKESGFQGFRVACCAFNTYVIEFLKKI
MEDVNRTKEASNEARLAIVELANMISVPMSLNAVVRLNVANAIWQSGSNTPLSASQILARVLPAGGGDAENLQRILRMLTSYGVFSEHLNADGSERKFSLTEIGQTLVTNQDGLSYGAYVLQHHQDELMRAWPLVHEAVVDPTVEPFVKANGEPAYQYYGKKPEMNGLMQKSMSGVSVPFMKAILDGCDCFEGVRRLVDVGGSAGDCLRMILDKHPNVTEGINFDLPEVVAKAPTIARVTHVGGDMFKAIPTADAIFMKWVLSTWTDRECKLILENCYKALPVGGKLICCEPMLPKKSDDSHRTRALLENDIFVMTIYRAKGKNRTEEEFRQLGHSVGFSYSRPIYIDYFFTVLEFKK
>Rf060218860
MEDLNQTKEAGNEARLAIVELANMISVPMSLIAVVRLNVADAIWQSGSNNPLSTSEILAHVLPAGSGDAENLQRILRMLTSYGVFSEHLNADGSERKFSLTEIGQTLVTTEDGLSYGAYILQHHQDALMRAWPLVHEVVVDPTVEPFVKANGEPAYQYYGKKPKMNRLMQKAMSGVSVPFMKAILEGYDGFEGVKRLVDVGGSAGDCLRMILDRHPNVTEGINFDLPEVVANAPTIAGVTHVGGDMLKSIPSGDAIFIKWVFSTWTNRECKLILENCYKALPVGGKLIFCEPMLPKKSDDSHRTRALLENDIFLMTMYQAKDTNRTEEEFRQLGYSAGFSHSRSIYIDYFFTVLEFQK
>Rf030105340
MESLGSLESHISARVLANSIAVQMTLRAAIELNVFNIIAKSGRGAHLTSKEIVSQISTTNPNLAVKNLERILRLLSVHSLLTTSQKSDPNDQTTQETSYGLTKETLCFVPNEDGVSCVPLVLWGSEMHCIKSLYMLKYTVLEPESSPFYKAHGEAFYEYMSETPDVSRLFDKVLGLTSYLHFDQKVFEVYRGFQEVKELMDVGGGDGAVIAKIVSVYPHIHGVNFNLPSVIAKAPTYQGVKHVGGDMFESIPSTQSIMLKSVLCDWDDEHCKKILKNCWEALPENGKVIVVEHNVLPEVVENTPEMMPILYCDIYMMALCPGGKERTTAELDNLAKSVGFVETIFFPISHGNYVIEFLKGNVN
>Rf050165680
MENQRISSTNHVSAWCLGSLIPTQMAIKAAIELNVFNIIANAGPGAHLSSKEIVSQISTTNPNAAVENLERILRVLSVHSFLSISQRPSSNSMKMLERTYGLTNASLFLVPNEDGVSLAPNVVLSSEMDIVKSLSMLKDTVLEPGCLPFNKAHGVSIYDHMSGKPELSQLFNKAVGQSSILDFEEVLKIYKGFEEVEELMDVGGGIGTTIQKVVSCYPHIHGINFDLPNVIAQGKAKYPGVKHVGGDMFELIPNVKSIMLKWVLHNWNDDQCKKILKRCWEALPKSGKVIVVEFAIPEILENTFEVIKIVSMDILMMTCPGGRERTIAEFDNLAKSVGFLDTKAFPISHGCYVMEFHKKKHI
>Rf050177800
MDLVEYLGGDARYGEVFKNSMKEFNPILMKEILENYTGFDGLNTLVDVGGADGTILNMIVSKYPTIKGINYDLASVIEKSPSYPGIEHIAGDMFVAIPKGDAIFMKVKLALGFYKQWVLHLYDDKRCLMILKNCYEALPKHGKMIVVNLVIPEAPEISVSAKSLFQFDMFLMNTTTTEKERTDREFESLAKQAGFYTIRVACSAFNFSVVELFKSM
>Rf050154470
MGTQGSLENHISALDIGNSLIIQMTLRAAIELDVFNIIAKSGPGAHLSSKEIVSQIPTTNSISAAMNLERMLNLLSVNSFLSISLRPATENDKTVQEKTYGLTKNALCLVPNEDGVSLAPLILLGSEMFTVQSLCMLKCSVLEPECSPFYKAHGEAYFEYMSKKPEFIQLFEKLMIVRSYLYFDHKVLEVYRGFKELKELTDVGGGDGSSTAKIVSMYPHIHGINFNLSSIIDQAPKYQGVKHVKGDMFKSIPKTQSIMLKEVLHNWDDEDCKQILKNCWEALPKTGKVIVVEYVIMPEVLKNTPEIVHSLAVDIMMMTLFSDDSWIPGIPLSKPSVETADVDMLAGVQELIVHPGTWNEDMIKETFSPIDAEAILANPY
>Rf050154480
MGIQGNLENHISALDIGNSLCVQMTIRAAIELDVFNIIAKSGPGAHLSSKEIVSQIPTTNSISAAKNLERMLNLLSVGSFLSISSRPATSNDNTVQEKTYGLTENALSLVPNEDGVSLTPLMIMNSNMSTVQSLYMLKHSVLEPDCSPFYKAHGEAYFEYMSKKPEFIELFDKVMRLSSSLHFDRKVLQVYRGFQELEELMDVGGGDGSSIAKIVSMYPHIHGTNFNLSSIIDQAPEYQGVKHVKGDMFKSIPKTQTIMLKAVLHNWDDEHCKKILRNCWEALPKSGKVIVVEYFMIPEELQNTPETLNLIAADIVMMTLTSGGKERTAADFDHLAKSVGFVETKVFPISQGTCVIEFLKREI
>Rf020041970
MGTQGSLENHISAFEIGNSLCIQMALRAAIELDVFNIIAKTGPGAHLSSKEFVSQIRTTNPILAARNLERILNLLSVNSLLSTSLRPTLNDETPQEKTYGLTRNALCLVPNEDGVSFAPVLMFCSEMHYVQSLYMLKHTVLEPECSPFYKGYGLTFYEYMSTKPEMIQLFDKAMSITSYMYFDKKVLEVYRGFQELKELMDVGGGDGSSVAKIVSTYPHIHGINFNLPSIIDEAPKYQGVKHVKGDMFESIPKTESIMLKWVLHNWDDNQCKKILKNCWEALPKTGKVIVVEYFVTPGVLENTPETRHTLMSDILMMSLFAGGKERTTAEFDDLAKSVGFIETKCFPISHGTCVIEFLKY
>Rf020059310
MSSTSSEITHTNTMSQQHDEEELGKLAIRLANVVILPMVLKSALELNVIDIIWAAGDGACLSPSDIAAQLPTDNSNAPVVLDRMLRLLASHSILKCSARTGPDGQVERLYGAGPICKFLVKDQNGGTGSVGPLFLLHHEKVFMESWFHLNDAVLEGGIPFNRAYGMTAFEYPETDERFNRVFNQAMSNHTTLILKKILDVYKGFEGINVLVDVGGGIGVTLNLITTKYPHIKGINFDLPHVLADAPSYPGVEHVGGDMFNSVPEGDAIFMKWILHDWSDEHCLTLLKNCCKSIPSSGKVIFVESILPEVPDCSITSNIVCEQDLLMFTQNPGGKERTKKEYEALALKSGFSRMEIVCSAYNSWVMEFHK
>Rf070234460
MFSSVPSGDAIFMKWILHDWSDEHCLKLLKNCYNAIPENGKVIVVEALLPVVPETSTAVKSTSQIDVLMMTQNPGGKERSEQEFIALATAAGFRGIRYECFVCNFWVMEFFK
>Rf070234450
MSMQSAVELGVFDIIAKAGPGAGLSSAKIAAQIGTKNAEAPMMLDRILRLLASHSVLNCTVVNANDGDHGDGPNFQRVYSLAPVSKYFVKSDEDGVSLGALMALIQDKVFLDSWFQLKGAVVEGGIPFNRVHGTHAFEYPGLDPRFNQVFNTAMFNHTTIVIKKILDLYKGFEHLKQLVDVGVALE
>Rf070265470
MGSTGETQMTPTQVSDEEANLFAMQLASASVLPMVLKAAIELDLLEIMAKAGPGAFLSPKDLAAHLPTKNPEAPVMLDRILRLLASYSILTYSLHTLPDGKVERLYGLGPVCKFLTKNEDGVSIAPLCLMNQDKVLIESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNRGMADHSTITMKKILETYKGFEGLTSIVDVGGGTGAVVNMIVSKYPSIKGINFDLPHVIEEAPQYPGVQHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKFLKNCYAALPDDGKVILGECILPVAPDTSLATKGVVHIDVIMLAHNPGGKERTEQEFEALAKESGFQGFRVACCAFNTYVIEFLKKI
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University