Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Rosmarinus officinalis
Species name
Rosemary (Salvia rosmarinus) is a species of eudicot in the family Lamiaceae (mint family).
Species info
Gene sequence info
Rosmarinus_officinalis.CHS.fa
Download
>1025.g36.t1
MFAGEKSMIKKRHMHLTEEILKQNPNICKDTAPSLDDRQHILVAEVPKLGLFGDGASAVIVGSDPVAAVENSLFDIVAAAQAFVPGTEEAMHGQLREVGIVRRLMRTIPGFISESIERCLEEAFGPLSLGVPDSNSIFWITHPGGPAIQDGIEAKLELRPDKLRATRRVLSMGI
>1069.g8.t1
MVTVEEIRRAQRAEGPATVLAIGTATPSNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEYLKKNPSVTAYMAPSLDLRQDIVVVEVPKLGKEAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRSSVKRFMMYQQGCFAGGTVLRMAKDLAENNAGARVLVVCSEITAVTFRGPSDSHLDSLVGQALFGDGAAAVIVGSDPVLGVERPLFELVSAAQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFGPLGITDWNSIFWIAHPGGPAILDQVEAKLELKPEKMRSTRHVLSEYGNMSSACVLFILDEMRKSSAKEGMATTGEGLEWGVLFGFGPGLTVETVVLHSVNIN
>1101.g6.t1
MVTVEEIRRAQRAQSPATVLAIGTATPSNCIDQSTFADYYFRITNSEHLTDLKEKFKRLCARSTINKRYMHMTEEYLKENPNMTSYMEPSLDTRQDLVVVEVPKLGQAAAEKAINEWGQPKSSITHLVFCTTSGADMPGADYQLTKLLGLRPSVKRFMMYQQGCFAGATALHMAKDFAENNAGARVLIVCSELNAITFRGPCDSHLDSLVHQALFGDGAAAVVVGADPIAGAESPLFELVAAAQTIVPGSDGAIRGHFREVGLTFHLKREVPDLISKNLEKILSEAFRPLGISDWNSVFLITHPGGPAILDKVEAELRLKPDKLRASRHVLSEYGNMSSATVLFILDHMRKSSANEGLSSTGEGLDWGALMGFGPGLTVEMVLLRSFAIN
>1722.g94.t1
MATVEEIRRAQRAEGPATVLAIGTAVPPNCIEQSTFPDFYFRVTNSEHMSDVKRKFKRMCENSKIKKRYTHLTEELLKENPKMTAYMAPSLNVRQDIVAVEVPNLGKEAAEKAIKEWGQPKVKITHLIFSTNSSVHMPGADYHLTNLLGLRPSVKRSMMYLQGCYGGASALRAAKDLAENNVDARVLVVNSETTTLGFRGPSEDHPENLVAQSLFGDAAAAVIVGSDPVSGAERPLFQIVSAAQAIIPNSDGAIVGRVREAGLVAHLRADVPALISGNIGVRLEEAFEPLGIRDWDSIFWIAHPGGAAILDRIEAGLGLKPEKLRLSRRVLNEYGNVSSATVLLILDEMRKASAEEGLSTTGEGLDWGVLFGFGPGLTVETVVLRSMPIN
>2684.g33.t1
MASVEEIRRAQRAEGPATVLAIGTATPPNCVDQSTFPDYYFRVTNSEHKADLKRKFKFICENSMIKKRYMHLTEELLKENPNIAAYTAPSLDSRQDMVAAEGPKLGKEAAEKAIKEWGQPKSNITHLIFCSSTIAVDMPGIDYQLTKLLGLDPSISRFVMCQHGCSGGASALRMAKDLAENNAAARVLVVCCEITAMCFRGPSEAHLGDLVGQALFGDAAAAVIVGSDTVAGAAELPLFQIISGAQTIIPDSYGGIRGRMREAGLVVDLRKDVPGLISDNIEESLKRAFGPWGISDWNSIFWIAHPGGPAILNRVETGLGLKPEKLRWSRHVLSEYGNVSSPTVLFILDAMRRSSAVEGRSTTGEGLDWGVLFGFGPGLTMETIVLRGMPLG
>2691.g40.t1
MPLTNQLHRRTPTPGKATILAIGKAFPRQLVLQDLLVEGYLRDTNCDDIAIKEKLQRLCKTTTVKTRYTVMSKEILDEYPELATEGSPTIKQRLDIAHPAVLEMAKEASMACLKEWKRPAQDITHIVYVSSSEIRLPGGDLYLATELGLRNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLATSETTILGFRPPNKSRPYDLVGAALFGDGAAAVVVGADPVSGAESPFMELNRAVQQFLPGTSHVIDGRLSEEGIYFKLGRDLPQKIEENIDEFCKKLMGGAGLGDYNELFWAVHPGGPAILNRVESVLGLEAGKLDCSRRALMDYGNVSSNTIFYVMEYMREELGKKRENCEEWGLALAFGPGITFEGILLRSLLH
>298394.g1.t1
MVTVEEILRAQRAEGPATVLAIGTATPSNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEYLKENPSVTAYMAPSLDLRQDIVVVEVPKLGKEAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRMAKDLAENNAGARVLVVCSEITAVTFRGPNDAHLDSLVGQALFGDGAAAVIVGSDPVVGVERPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFGPLGISDWNSVFWIAHPGGPAILDMVEAKLELKPEKLRSTRHVLSEYGNMSSACVLFILDEMRKSSAKEGMGTTGEGLEWGVLFGFGPGLTVETVVLHSVNIN
>386504.g1.t1
MSLNGQTNHLRRRTPTPGKATILAIGKAFPRQLVLQDLLVEGYIRDTNCDDLAIKEKLQRLCKTTTVKTRYTVMSKEILDEYPELATEGSPTIKQRLDIAHPAVLEMAKEASLACLKEWKRPAQDITHVVYVSSSEIRLPGGDLYLATELGLRNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLATSETTILGFRPPNKSRPYDLVGAALFGDGAAAVVVGADPVSGVESAFMELNTAVQQFLPGTSHVIDGRLSEEGIYFKLGRDLPQKIEENIEEFCKKLMGGAGLGDYNELFWAVHPGGPAILNRLESVLGLDGGKLDCSRRALMDYGNVSSNTIFYVMEYMREELGKKENCEEWGLALAFGPGITFEGILLRSLL
MFAGEKSMIKKRHMHLTEEILKQNPNICKDTAPSLDDRQHILVAEVPKLGLFGDGASAVIVGSDPVAAVENSLFDIVAAAQAFVPGTEEAMHGQLREVGIVRRLMRTIPGFISESIERCLEEAFGPLSLGVPDSNSIFWITHPGGPAIQDGIEAKLELRPDKLRATRRVLSMGI
>1069.g8.t1
MVTVEEIRRAQRAEGPATVLAIGTATPSNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEYLKKNPSVTAYMAPSLDLRQDIVVVEVPKLGKEAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRSSVKRFMMYQQGCFAGGTVLRMAKDLAENNAGARVLVVCSEITAVTFRGPSDSHLDSLVGQALFGDGAAAVIVGSDPVLGVERPLFELVSAAQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFGPLGITDWNSIFWIAHPGGPAILDQVEAKLELKPEKMRSTRHVLSEYGNMSSACVLFILDEMRKSSAKEGMATTGEGLEWGVLFGFGPGLTVETVVLHSVNIN
>1101.g6.t1
MVTVEEIRRAQRAQSPATVLAIGTATPSNCIDQSTFADYYFRITNSEHLTDLKEKFKRLCARSTINKRYMHMTEEYLKENPNMTSYMEPSLDTRQDLVVVEVPKLGQAAAEKAINEWGQPKSSITHLVFCTTSGADMPGADYQLTKLLGLRPSVKRFMMYQQGCFAGATALHMAKDFAENNAGARVLIVCSELNAITFRGPCDSHLDSLVHQALFGDGAAAVVVGADPIAGAESPLFELVAAAQTIVPGSDGAIRGHFREVGLTFHLKREVPDLISKNLEKILSEAFRPLGISDWNSVFLITHPGGPAILDKVEAELRLKPDKLRASRHVLSEYGNMSSATVLFILDHMRKSSANEGLSSTGEGLDWGALMGFGPGLTVEMVLLRSFAIN
>1722.g94.t1
MATVEEIRRAQRAEGPATVLAIGTAVPPNCIEQSTFPDFYFRVTNSEHMSDVKRKFKRMCENSKIKKRYTHLTEELLKENPKMTAYMAPSLNVRQDIVAVEVPNLGKEAAEKAIKEWGQPKVKITHLIFSTNSSVHMPGADYHLTNLLGLRPSVKRSMMYLQGCYGGASALRAAKDLAENNVDARVLVVNSETTTLGFRGPSEDHPENLVAQSLFGDAAAAVIVGSDPVSGAERPLFQIVSAAQAIIPNSDGAIVGRVREAGLVAHLRADVPALISGNIGVRLEEAFEPLGIRDWDSIFWIAHPGGAAILDRIEAGLGLKPEKLRLSRRVLNEYGNVSSATVLLILDEMRKASAEEGLSTTGEGLDWGVLFGFGPGLTVETVVLRSMPIN
>2684.g33.t1
MASVEEIRRAQRAEGPATVLAIGTATPPNCVDQSTFPDYYFRVTNSEHKADLKRKFKFICENSMIKKRYMHLTEELLKENPNIAAYTAPSLDSRQDMVAAEGPKLGKEAAEKAIKEWGQPKSNITHLIFCSSTIAVDMPGIDYQLTKLLGLDPSISRFVMCQHGCSGGASALRMAKDLAENNAAARVLVVCCEITAMCFRGPSEAHLGDLVGQALFGDAAAAVIVGSDTVAGAAELPLFQIISGAQTIIPDSYGGIRGRMREAGLVVDLRKDVPGLISDNIEESLKRAFGPWGISDWNSIFWIAHPGGPAILNRVETGLGLKPEKLRWSRHVLSEYGNVSSPTVLFILDAMRRSSAVEGRSTTGEGLDWGVLFGFGPGLTMETIVLRGMPLG
>2691.g40.t1
MPLTNQLHRRTPTPGKATILAIGKAFPRQLVLQDLLVEGYLRDTNCDDIAIKEKLQRLCKTTTVKTRYTVMSKEILDEYPELATEGSPTIKQRLDIAHPAVLEMAKEASMACLKEWKRPAQDITHIVYVSSSEIRLPGGDLYLATELGLRNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLATSETTILGFRPPNKSRPYDLVGAALFGDGAAAVVVGADPVSGAESPFMELNRAVQQFLPGTSHVIDGRLSEEGIYFKLGRDLPQKIEENIDEFCKKLMGGAGLGDYNELFWAVHPGGPAILNRVESVLGLEAGKLDCSRRALMDYGNVSSNTIFYVMEYMREELGKKRENCEEWGLALAFGPGITFEGILLRSLLH
>298394.g1.t1
MVTVEEILRAQRAEGPATVLAIGTATPSNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEYLKENPSVTAYMAPSLDLRQDIVVVEVPKLGKEAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRFMMYQQGCFAGGTVLRMAKDLAENNAGARVLVVCSEITAVTFRGPNDAHLDSLVGQALFGDGAAAVIVGSDPVVGVERPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLKEAFGPLGISDWNSVFWIAHPGGPAILDMVEAKLELKPEKLRSTRHVLSEYGNMSSACVLFILDEMRKSSAKEGMGTTGEGLEWGVLFGFGPGLTVETVVLHSVNIN
>386504.g1.t1
MSLNGQTNHLRRRTPTPGKATILAIGKAFPRQLVLQDLLVEGYIRDTNCDDLAIKEKLQRLCKTTTVKTRYTVMSKEILDEYPELATEGSPTIKQRLDIAHPAVLEMAKEASLACLKEWKRPAQDITHVVYVSSSEIRLPGGDLYLATELGLRNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLATSETTILGFRPPNKSRPYDLVGAALFGDGAAAVVVGADPVSGVESAFMELNTAVQQFLPGTSHVIDGRLSEEGIYFKLGRDLPQKIEENIEEFCKKLMGGAGLGDYNELFWAVHPGGPAILNRLESVLGLDGGKLDCSRRALMDYGNVSSNTIFYVMEYMREELGKKENCEEWGLALAFGPGITFEGILLRSLL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University