Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Rosa chinensis
Species name
China rose (Rosa chinensis) is a species of eudicot in the family Rosaceae (rose family).
Species info
Gene sequence info
Rosa_chinensis.4CL.fa
Download
>rna-XM_024323782.2
MISIASNNNNSVVVETPEISPTLISDVVSTSQTQPEKQQPAITTHHDHVFKSKLPDLPNISNHLPLHTYCFENISDFSDRPCLIVGSTGKTYTFSETHLISQKTGAGLSKLGITKGDVIMILLPNCAEFTFAFMGASMIGAVTTTANPFYTASEIFKQFKASNAKLIITQSTYVDKLRHSGTSSDQYPMLGEHFQVVTIDDPPMNCLHFSVLSDANENELPEVSIDPEDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLKEDDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLVMHKFEIGTLLELIQKYRVSVAAVVPPLVIALAKNPMVADYDLSSIRAILSGAAPLGKDLEEALRSRVPQAVLGQGYGMTEAGPVLSMCLAFAKQPFPTKSGSCGTVVRNAELKVIEPETGRSLGYNQPGEICIRGSQIMKGYLNDDEATATTVDVEGWLHTGDVGYVDDDNEVFIVDRVKELIKFKGFQVPPAELEALLVCHQSIADAAVVPQKDDAAGEVPVAFVVRSNGNELTEEAIKEFVAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLATPNV
>rna-XM_024329662.2
MAIETPQSDIIYRSKLPDIPIPNHLPLHSYIFQNKSHLSSKPCIINGTTGEIHTYADVELTARKVASGLNKLGIKQGDVVMLLLPNTPEFVFTFLGASFRGAMTTAANPFFTPAEIAKQAKASKAKLIITLAIYYDKVKELSCDEVKLMCIDSPPPDSSCLHFSELTQSNEDDVPEVDISPNDVVLLPYSSGTTGLPKGVMLTHKGLVTSVSQQVDGENPNLYYNSDDVVLCVLPLFHIYSLNSVLLCGLRAGAAILVMQKFEIVSLLELMQKHRVSVAPVAPPIVLAIAKFPDLDKYDLGSIRVLKSGGAPLGKELEDTVRAKFPSVTLGQGYGMTEAGPVLTMSLAFAKEPFEVKPGGCGTVVRNAEMKIVDPETGASLPRNQPGEICIRGHQIMKGYLNDPEATSTTIDKEGWLHTGDIGFIDDDEELFIVDRLKEIIKYKGFQVAPAELEALLVTHPNISDAAVVSMKHDAAGEVPVAFVVRSNGSQITEDEIKQFISKQVIYYKRINRVFFIEAIPKSPSGKILRKELRAKLAAGSAN
>rna-XM_024340569.2
MGTLVPSSAQDLQEHIFRSQLPAVQVPENLTLPEFVLKDAELYADNVAFVEAVTGKKITYREVVRDTGRFAKALRSLGLRKGHVVIVVLPNVAEYAIVALGIMAAGGVFSGANPAGHASEIKKQVVAADAKIIVTNGASYEKVKAFGVPVIAIGEETIEGAMNWNNLLEAADRAGANIYQEKVQQTDLCALPFSSGTTGLSKGVMLTHRNLVANLSSTLFGVTPEMIGKVTVLGLIPFFHIYGITGICCATLRNKGKVVVMGRYELRTFLNALISQEVTFAPIVPPIILNLVKHPIVDEFDLSKLKLQAVMTAAAPLAPDLLKAFESKFPGVQVQEAYGLTEHSCITLTHAGQGFKAKKNSVGFILPNMEVKFIDPETGRSLPRNTPGEICVLSQCTMQGYYNNEEETMRTIDKNGWLHTGDIGYIDYDDNVFIVDRIKELIKFKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPAACVVKAAGAKESQEDIINYVASNVAQYKKVRVVHFVDTIPKSPSGKIMRRLVKDTMIEKIKASKLSSN
>rna-XM_024338214.2
MENKQDSHEFIFRSKLPDIYIPNHLPLHTYCFENISQFHDRPCLINGNTGETFTYADVELTSRRVAAGLDKLGIHQGDVVMLLLQNCPEFAFAFLGASYVGGIITTANPFYTPAEVAKQATASNAKLIITQAAYVDKVKDFAKLNNVRLMCVDETSSSSSEDVLHFSQLSSADESETPAVKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHKEDVILCVLPLFHIYSLNSVFLCGLRVGATILIMQKFEINKLLELVEKEKVTIAPFVPPIVLNIAKSPDLHRYDLSSIRMVMSGAAPMGKELEDTVRAKLPDAKLGQGYGMTEAGPVLSMCLAFAKEPYEIKSGACGTVVRNAEMKIIDPDTNESLPRNQSGEICIRGSQIMKGYLNDPEATERTIDKEGWLHTGDIGYIDDDDEIFIVDRLKELIKYKGFQVAPAELEAMLISHPNLSDAAVVPMKDEAAGEVPIAFVVRSNGSKISEDDIKQYISKQVVFYKRISRVFFTDKIPKAPSGKILRKDLRARLAAGLPN
>rna-XM_024302094.2
METSGYGRDGVFRSLRPPLVLPRDPNLSMVSFLFKNSSFYPHKPALIDTESSETLSFSQFKSTVIKVAHGLIHLGIKKHDVVLIFAPNSIQFPIFFLGIIAVGAIATTSNPLYTVSELSKQIKDSNPKLVITVPELWEKVKGLNLPAVILGPKGSSSQIESSSRIVGFHDLVQLSGPVSDFPSVNVKQTDTAALLYSSGTTGLSKGVILTHGNFIASSLMITQDQEVAGEMHHVFLCVLPMFHMFGLAVITYAQLRKGNAVISMSRFNLEKILMTVEKYKVTHLWVVPPIILALSKDSVVKKYNLSSLKHIASGAAPLGKELMEECAKIIPQGVVIQGYGMTETCGIISIENSLVGPRHSGSAGTLVSGVESQIVSVDTLKPLPPKQLGEIWVRGPSMMMGYFNNPQATQLTLDKNGWVHTGDLGYFDESGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEEDIKSFIASQVASFKRLRRVTFINTVPKSASGKILRKEIIEKVRSKI
>rna-XM_024302093.2
METSGYGRDGVFRSLRPPLVLPRDPNLSMISFLFKNSSSYPHKPALIDAESSETLSFSQLKSTVIKVAHGLIHLGIKKHDVVLIFAPNSIQFPIFFLGIIAVGAIATTSNPLYTVSELSKQVKDSNPKLVITVPELWEKVKGLNLPVVILGPKGSSSQIESSSRIVGFHDMVQLSGPVSDFPSVNVKQTDTAALLYSSGTTGLSKGVILTHGNFIASSLMNTQDQEVAGEMHHVFLCVLPMFHLFGLAVITYAQLRKGNTVISMSRFNLEKILMTVEKYKVTHLWVVPPIILALSKDSVVKKYNLSSLKHIGSGAAPLGKELMEECAKIIPQGVVIQGYGMTETCGLISIENSLVGPRHSGSAGTLVSGVESQIVSVDTLKPLPPKQLGEIWVRGPSMMMGYFNNPQATQLTLDKNGWVHTGDLGYFDESGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVAYVVRSLNSSLTEEDIKSFIASQVASFKRLRRVTFINTVPKSASGKILRKELIEKVRSKI
>rna-XM_024301095.2
MEKSGYGRDGVFRSLRPPLVLPRDPNLTMVSFLFKNSSSYPHRPALIDAESSETLSFSQLKSTVIKVAHGLIHLGIKKNDVVLIFAPNSIQFPICFLGIIAIGAIATTSNPLYTVSELSKQVKDSNPKLVITVPELWEKVKGLNLPAVILGPKGSSSQIESSSRIVGFHDLVQLSGPVSDFPSVNVKQTDTAALLYSSGTTGLSKGVILTHGNFIASSLMITQDQEVAGEMHNVYLCVLPMFHVFGLAVITYAQLRKGNAVISMSRFNLEKVLMTVEKFKVTHLWLVPPIILALSKDSVVKKYSLSSLKHIGSGAAPLGKELMEECAKIIPQGVVSQGYGMTETCGIVSVENTLVGPRHSGSAGTLVSGVESQIVSVDTLKPLPPKQLGEIWVRGPNMMMGYFNNPQATQLTLDKNGWVHTGDLGYFDESGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVAYVVRSPNSSLTEEDIKSFIASQVASFKRLRRVTFINTVPKSASGKILRKELIEKVRSKI
MISIASNNNNSVVVETPEISPTLISDVVSTSQTQPEKQQPAITTHHDHVFKSKLPDLPNISNHLPLHTYCFENISDFSDRPCLIVGSTGKTYTFSETHLISQKTGAGLSKLGITKGDVIMILLPNCAEFTFAFMGASMIGAVTTTANPFYTASEIFKQFKASNAKLIITQSTYVDKLRHSGTSSDQYPMLGEHFQVVTIDDPPMNCLHFSVLSDANENELPEVSIDPEDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLKEDDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLVMHKFEIGTLLELIQKYRVSVAAVVPPLVIALAKNPMVADYDLSSIRAILSGAAPLGKDLEEALRSRVPQAVLGQGYGMTEAGPVLSMCLAFAKQPFPTKSGSCGTVVRNAELKVIEPETGRSLGYNQPGEICIRGSQIMKGYLNDDEATATTVDVEGWLHTGDVGYVDDDNEVFIVDRVKELIKFKGFQVPPAELEALLVCHQSIADAAVVPQKDDAAGEVPVAFVVRSNGNELTEEAIKEFVAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLATPNV
>rna-XM_024329662.2
MAIETPQSDIIYRSKLPDIPIPNHLPLHSYIFQNKSHLSSKPCIINGTTGEIHTYADVELTARKVASGLNKLGIKQGDVVMLLLPNTPEFVFTFLGASFRGAMTTAANPFFTPAEIAKQAKASKAKLIITLAIYYDKVKELSCDEVKLMCIDSPPPDSSCLHFSELTQSNEDDVPEVDISPNDVVLLPYSSGTTGLPKGVMLTHKGLVTSVSQQVDGENPNLYYNSDDVVLCVLPLFHIYSLNSVLLCGLRAGAAILVMQKFEIVSLLELMQKHRVSVAPVAPPIVLAIAKFPDLDKYDLGSIRVLKSGGAPLGKELEDTVRAKFPSVTLGQGYGMTEAGPVLTMSLAFAKEPFEVKPGGCGTVVRNAEMKIVDPETGASLPRNQPGEICIRGHQIMKGYLNDPEATSTTIDKEGWLHTGDIGFIDDDEELFIVDRLKEIIKYKGFQVAPAELEALLVTHPNISDAAVVSMKHDAAGEVPVAFVVRSNGSQITEDEIKQFISKQVIYYKRINRVFFIEAIPKSPSGKILRKELRAKLAAGSAN
>rna-XM_024340569.2
MGTLVPSSAQDLQEHIFRSQLPAVQVPENLTLPEFVLKDAELYADNVAFVEAVTGKKITYREVVRDTGRFAKALRSLGLRKGHVVIVVLPNVAEYAIVALGIMAAGGVFSGANPAGHASEIKKQVVAADAKIIVTNGASYEKVKAFGVPVIAIGEETIEGAMNWNNLLEAADRAGANIYQEKVQQTDLCALPFSSGTTGLSKGVMLTHRNLVANLSSTLFGVTPEMIGKVTVLGLIPFFHIYGITGICCATLRNKGKVVVMGRYELRTFLNALISQEVTFAPIVPPIILNLVKHPIVDEFDLSKLKLQAVMTAAAPLAPDLLKAFESKFPGVQVQEAYGLTEHSCITLTHAGQGFKAKKNSVGFILPNMEVKFIDPETGRSLPRNTPGEICVLSQCTMQGYYNNEEETMRTIDKNGWLHTGDIGYIDYDDNVFIVDRIKELIKFKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPAACVVKAAGAKESQEDIINYVASNVAQYKKVRVVHFVDTIPKSPSGKIMRRLVKDTMIEKIKASKLSSN
>rna-XM_024338214.2
MENKQDSHEFIFRSKLPDIYIPNHLPLHTYCFENISQFHDRPCLINGNTGETFTYADVELTSRRVAAGLDKLGIHQGDVVMLLLQNCPEFAFAFLGASYVGGIITTANPFYTPAEVAKQATASNAKLIITQAAYVDKVKDFAKLNNVRLMCVDETSSSSSEDVLHFSQLSSADESETPAVKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHKEDVILCVLPLFHIYSLNSVFLCGLRVGATILIMQKFEINKLLELVEKEKVTIAPFVPPIVLNIAKSPDLHRYDLSSIRMVMSGAAPMGKELEDTVRAKLPDAKLGQGYGMTEAGPVLSMCLAFAKEPYEIKSGACGTVVRNAEMKIIDPDTNESLPRNQSGEICIRGSQIMKGYLNDPEATERTIDKEGWLHTGDIGYIDDDDEIFIVDRLKELIKYKGFQVAPAELEAMLISHPNLSDAAVVPMKDEAAGEVPIAFVVRSNGSKISEDDIKQYISKQVVFYKRISRVFFTDKIPKAPSGKILRKDLRARLAAGLPN
>rna-XM_024302094.2
METSGYGRDGVFRSLRPPLVLPRDPNLSMVSFLFKNSSFYPHKPALIDTESSETLSFSQFKSTVIKVAHGLIHLGIKKHDVVLIFAPNSIQFPIFFLGIIAVGAIATTSNPLYTVSELSKQIKDSNPKLVITVPELWEKVKGLNLPAVILGPKGSSSQIESSSRIVGFHDLVQLSGPVSDFPSVNVKQTDTAALLYSSGTTGLSKGVILTHGNFIASSLMITQDQEVAGEMHHVFLCVLPMFHMFGLAVITYAQLRKGNAVISMSRFNLEKILMTVEKYKVTHLWVVPPIILALSKDSVVKKYNLSSLKHIASGAAPLGKELMEECAKIIPQGVVIQGYGMTETCGIISIENSLVGPRHSGSAGTLVSGVESQIVSVDTLKPLPPKQLGEIWVRGPSMMMGYFNNPQATQLTLDKNGWVHTGDLGYFDESGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEEDIKSFIASQVASFKRLRRVTFINTVPKSASGKILRKEIIEKVRSKI
>rna-XM_024302093.2
METSGYGRDGVFRSLRPPLVLPRDPNLSMISFLFKNSSSYPHKPALIDAESSETLSFSQLKSTVIKVAHGLIHLGIKKHDVVLIFAPNSIQFPIFFLGIIAVGAIATTSNPLYTVSELSKQVKDSNPKLVITVPELWEKVKGLNLPVVILGPKGSSSQIESSSRIVGFHDMVQLSGPVSDFPSVNVKQTDTAALLYSSGTTGLSKGVILTHGNFIASSLMNTQDQEVAGEMHHVFLCVLPMFHLFGLAVITYAQLRKGNTVISMSRFNLEKILMTVEKYKVTHLWVVPPIILALSKDSVVKKYNLSSLKHIGSGAAPLGKELMEECAKIIPQGVVIQGYGMTETCGLISIENSLVGPRHSGSAGTLVSGVESQIVSVDTLKPLPPKQLGEIWVRGPSMMMGYFNNPQATQLTLDKNGWVHTGDLGYFDESGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVAYVVRSLNSSLTEEDIKSFIASQVASFKRLRRVTFINTVPKSASGKILRKELIEKVRSKI
>rna-XM_024301095.2
MEKSGYGRDGVFRSLRPPLVLPRDPNLTMVSFLFKNSSSYPHRPALIDAESSETLSFSQLKSTVIKVAHGLIHLGIKKNDVVLIFAPNSIQFPICFLGIIAIGAIATTSNPLYTVSELSKQVKDSNPKLVITVPELWEKVKGLNLPAVILGPKGSSSQIESSSRIVGFHDLVQLSGPVSDFPSVNVKQTDTAALLYSSGTTGLSKGVILTHGNFIASSLMITQDQEVAGEMHNVYLCVLPMFHVFGLAVITYAQLRKGNAVISMSRFNLEKVLMTVEKFKVTHLWLVPPIILALSKDSVVKKYSLSSLKHIGSGAAPLGKELMEECAKIIPQGVVSQGYGMTETCGIVSVENTLVGPRHSGSAGTLVSGVESQIVSVDTLKPLPPKQLGEIWVRGPNMMMGYFNNPQATQLTLDKNGWVHTGDLGYFDESGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVAYVVRSPNSSLTEEDIKSFIASQVASFKRLRRVTFINTVPKSASGKILRKELIEKVRSKI
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University