Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Rorippa islandica
Species name
Rorippa islandica is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Rorippa_islandica.4CL.fa
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>Roisl.0006s0223.1.v1.1
MAPQQEVIEKQSTNSDIIFRSRLPDIYIPNHLPLHDYVFQNISEFSSKPCLINGPTGQVYTYSDVHVISRQIAASFHKLGVNQYDVVMILLPNCPEFVLSFLAASFRGAIATAANPFFTPAEIAKQAKASNTKLIVTESRYVDKIKSLQNDDGVIIVCTDQSESVPIPEGCLRFSELTQSIESDVIDSVEISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHRDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEINLLLELIQRCKVTVAPIVPPIVLAIAKSLETEKYDLSSIRVVKSGAAPLGKELEDAVSVKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGDSLSRNKPGEICIRGHQIMKGYLNNPTATLETIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVAPAELEALLISHPDITDVAVVAMKEEAAGEVPVAFVVKSKDSDLSEDEVKQFVSKQVVFYKRINKVFFADSIPKAPSGKILRKDLRAKLANGL
>Roisl.0010s0118.1.v1.1
MEGQKQDNEHIFRSLYPSVPIPDKLTLPEFVLQGVEEFTEKVAFVEAVTGKSVTYGDVVRDTKRLAKALTSLGLRKGQVTVVVLPNVAEYGIIALGIMSAGGVFSGANPTALVSEIKKQVEASGARGIITDATNFEKVRTLGLPVIVLGEEKIEGAVNWKDLLEAGDRSGDNDKEEILQTDLCALPFSSGTTGLQKGVMLTHRNLIANLCSSLFSVRSEMIGQIVTLGLIPFFHIYGIVGICCATMKNKGKVVAMSRYDLRIFLNALIVHEVSFAPIVPPIILNLVKNPIVDEFDLSKLKLRSVMTAAAPLAPELLTAFEAKFPNVQVQEAYGLTEHSCITLTHGDPEKGQGIAKRNSVGFILPNLEVKFIDPDTGLSLPKNTSGELCVRSQCVMQGYFENKEETEKTIDEEGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPAACVVINPKAKEKEEDILNFVAANVAHYKKVRAVHFVDSIPKSLSGKIMRRLLRDKILSINKK
>Roisl.0021s0636.1.v1.1
MITAALHEPQIHKPADASPPTVVPGDAPSPPTPRIFRSKLPDIYIPNHLPLHTYCFEKLSSVSDKPCLIVGSTGKSYTYGETHHICRRVAAGLYKMGIRKGDVIMILLQNSAEFVFSFMGASMIGAVSTTANPFYTSQEIYKQLQSSGAKLIITHSHYVDKLRNLGEDLTVITTDDPTPENCLPFSILTDETNPPEESVDVGGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGDNPNIYLKSNDVVLCVLPLFHIYSLNSVLLNSIRSGATVLLMHKFEIGALLDLIQRHRVTMAALVPPLVIALAKNPAVNSYDLSSVRLVLSGAAPLGKDLQDSLRRRLPQAVLGQGYGMTEAGPVLSMSLGFAKEPIPTKSGSCGTVVRNAELKVVHVETRLSLGYNQPGEICIRGQQIMKEYLNDPEATSATIDEEGWLHTGDIGYVDEDDEIFIVDRLKEVIKFKGFQVPPAELESLLINHHAIADAAVVPQRDEVAGEVPVAFVVRSNGNNITEEEIKEYISKQVVFYKRLHKVFFVPSIPKSPAGKILRKDLKAKLS
>Roisl.0082s0274.1.v1.1
MEKSGYGRDGIYRSLRPKLILPKDPNTSLVSFLFRNSSSYSSKPALIDSESGDSFTFAQLKSAVSRLAHGFQRLGIRKNDVVLIFAPNSYQFPLCFLAVTAIGGVFTTANPLYTVSEVSKQIKDSNPKIIISVTQLFDKIKDFNLPIVLLGSNESTQIPHGSNSKILSFNEVMELSEPVSDLPVVEIKQSDTATLLYSSGTTGMSKGVELSHGNYVAASLMVTMDQDLMGEYHGVFLCFLPMFHVFGLSVITYSQLQRGNALISMSKFELETVLKNIEKYRVTHLWVVPPVFLALSKQSIVKSYDLSSLKYIGSGAAPLGKDLMEDCGRNIPNVMLMQGYGMTETCGIVSVEDPRLGKRNTGSAGMLAPGVEAQIVSVETGKYQPPNQLGEIWVRGPNMMKGYFNNPQATKETIDKKGWVHTGDLGYFNEDGNLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDEEAGEVPIAFVVRPPNSSVSEEDIQKFIAKQVAPFKRLRRVSFINTVPKSAAGKILRRELIQKVKSKL
>Roisl.0091s0406.1.v1.1
MAATNLHISSNTKTPKSHQNPPFWFSPETGIYTSIFPSVHLPVDPNLDAVTALFSHRHDGDAALIDSLTGFSISHIELQSMVQSMAAGIYHNLGVQQGDTVSLILPNSVYFPIIFLSLLSLGVIVTTMNPSSSLGEIKKQVSECNVGLAFTSTENVEKLSSLGIIVIRVPESYDFDLIRIENPKFYSIVKGGFGFVPKPLIKQDDVAATMYSSGTTGASKGVLLTHRNLIATMELFVRFEASQYEYPGSSNVYLAALPLGHIYGLSLFVLGLLSLGSTIVVMRRFDASDVINVIERFKITHFPVVPPMLMALTKKAKGVCGEVFKSLKQVSSGAAPLSRKFIEDFLQTLPHVDLIQGYGMTESTAVGTRGFNSEKLRSYCSVGLLAPNMQAKVVDWSSGSFLPPGNRGELWIQGPGVMKGYLNNPEATQMIIVEDSWLRTGDIAYFDEDGYLFIVDRIKEIIKYKGFQIAPADLEAVLVSHPLIIDAAVTAAPNEECGEIPVAFVVRRQETTLSEQDVINYVAAQVAPYRKVRKVVMVSSIPKSPAGKILRKELKRVLANCVSSRL
>Roisl.0115s0466.1.v1.1
MSSQEVMINDQKQRSSEVIFRSKLPDIYIPNHLAFHDYIFQNISEFAAKPCLINGVTGEVYSYADVHVTSRKLAAGLQKLGVNQHDVVMLLLKNSPELVLTFLAVSFIGAITTAANPFFTPAEISKQSKSSAAKLIVTESKYVNKIKILQNDGVSIICTDDSSAIPEGCIRFSELTQSGEEEQNLETKISPDDVVQVDGENPNIYFHREDVILCVLPMFHIYAFNCIVLCSLRVGATILILPKFEIGLLLEQIQRFKVTVAMVVPPIVLAIVKSQETEKYDLSSVRIIRSGAAPFGKELEDAISAKFPNAKLGQGYGMTETGPIAMSLGFAKQPFPMKSGACGTVVSNAEMKIIDPTTGDSLPRNKSGEICIRGHQIMKGYLNDPVATASTIDKDGWLHTGDVGFVDDDDELFIIDRLKELIKYKGFQVAPAELESLLIAHPHINDVAVVAMKEEDAGEVPVAFVVRTKDSNISEDEIKLLVSKQVVFYKRINRVFFTDSIPKAPSGKILRKDLRARLANGLMK
>Roisl.0115s0465.1.v1.1
MVLQQQTLFLTKKTDQEPSHDFIFRSKLPDIFIPNHLPLIDYVFQRFSGDGDGDSTSTCLIDGSTGRVFTYADVQTNSRRIAAGIHRLGIGHRDVVMLLLPNSPEFALSFLAVAYLGAISTTANPFYMQPEIEKQAKASTAKLIITKRCYVDKLTNLKNDGVLIVCVEDGDDDVVSLDGRVSFTELIQADETELPKPDISPEDTVAMPYSSGTTGLPKGVMITHKGLVTSIAQKVDGDNPNLNFTADDVILCFLPMFHIYALDALMLSAMRTGAALLIVPRFELNLVMELIQRYKVTVVPVAPPVVLAFVKSPETERYDLSSVRMMLSGAATLKKELEEAVRLKFPNAIFGQGYGMTESGTVAKSLAFAKNPFKTKSGACGTVIRNAEMKVVDTVTGVSLPRNQSGEICVRGHQLMKGYLNDPEATARTIDKDGWLHTGDIGFVDDDDEIFIVDRLKELIKFKGYQVAPAELEALLISHPCIDDAAVVAMKDEVADEVPVAFVVRSEGSQLTEDDVKSYVNKQVVHYKRIKKVFFIEAIPKAVSGKILRKELRAKLETEYSK
MAPQQEVIEKQSTNSDIIFRSRLPDIYIPNHLPLHDYVFQNISEFSSKPCLINGPTGQVYTYSDVHVISRQIAASFHKLGVNQYDVVMILLPNCPEFVLSFLAASFRGAIATAANPFFTPAEIAKQAKASNTKLIVTESRYVDKIKSLQNDDGVIIVCTDQSESVPIPEGCLRFSELTQSIESDVIDSVEISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHRDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEINLLLELIQRCKVTVAPIVPPIVLAIAKSLETEKYDLSSIRVVKSGAAPLGKELEDAVSVKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGDSLSRNKPGEICIRGHQIMKGYLNNPTATLETIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVAPAELEALLISHPDITDVAVVAMKEEAAGEVPVAFVVKSKDSDLSEDEVKQFVSKQVVFYKRINKVFFADSIPKAPSGKILRKDLRAKLANGL
>Roisl.0010s0118.1.v1.1
MEGQKQDNEHIFRSLYPSVPIPDKLTLPEFVLQGVEEFTEKVAFVEAVTGKSVTYGDVVRDTKRLAKALTSLGLRKGQVTVVVLPNVAEYGIIALGIMSAGGVFSGANPTALVSEIKKQVEASGARGIITDATNFEKVRTLGLPVIVLGEEKIEGAVNWKDLLEAGDRSGDNDKEEILQTDLCALPFSSGTTGLQKGVMLTHRNLIANLCSSLFSVRSEMIGQIVTLGLIPFFHIYGIVGICCATMKNKGKVVAMSRYDLRIFLNALIVHEVSFAPIVPPIILNLVKNPIVDEFDLSKLKLRSVMTAAAPLAPELLTAFEAKFPNVQVQEAYGLTEHSCITLTHGDPEKGQGIAKRNSVGFILPNLEVKFIDPDTGLSLPKNTSGELCVRSQCVMQGYFENKEETEKTIDEEGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPAACVVINPKAKEKEEDILNFVAANVAHYKKVRAVHFVDSIPKSLSGKIMRRLLRDKILSINKK
>Roisl.0021s0636.1.v1.1
MITAALHEPQIHKPADASPPTVVPGDAPSPPTPRIFRSKLPDIYIPNHLPLHTYCFEKLSSVSDKPCLIVGSTGKSYTYGETHHICRRVAAGLYKMGIRKGDVIMILLQNSAEFVFSFMGASMIGAVSTTANPFYTSQEIYKQLQSSGAKLIITHSHYVDKLRNLGEDLTVITTDDPTPENCLPFSILTDETNPPEESVDVGGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGDNPNIYLKSNDVVLCVLPLFHIYSLNSVLLNSIRSGATVLLMHKFEIGALLDLIQRHRVTMAALVPPLVIALAKNPAVNSYDLSSVRLVLSGAAPLGKDLQDSLRRRLPQAVLGQGYGMTEAGPVLSMSLGFAKEPIPTKSGSCGTVVRNAELKVVHVETRLSLGYNQPGEICIRGQQIMKEYLNDPEATSATIDEEGWLHTGDIGYVDEDDEIFIVDRLKEVIKFKGFQVPPAELESLLINHHAIADAAVVPQRDEVAGEVPVAFVVRSNGNNITEEEIKEYISKQVVFYKRLHKVFFVPSIPKSPAGKILRKDLKAKLS
>Roisl.0082s0274.1.v1.1
MEKSGYGRDGIYRSLRPKLILPKDPNTSLVSFLFRNSSSYSSKPALIDSESGDSFTFAQLKSAVSRLAHGFQRLGIRKNDVVLIFAPNSYQFPLCFLAVTAIGGVFTTANPLYTVSEVSKQIKDSNPKIIISVTQLFDKIKDFNLPIVLLGSNESTQIPHGSNSKILSFNEVMELSEPVSDLPVVEIKQSDTATLLYSSGTTGMSKGVELSHGNYVAASLMVTMDQDLMGEYHGVFLCFLPMFHVFGLSVITYSQLQRGNALISMSKFELETVLKNIEKYRVTHLWVVPPVFLALSKQSIVKSYDLSSLKYIGSGAAPLGKDLMEDCGRNIPNVMLMQGYGMTETCGIVSVEDPRLGKRNTGSAGMLAPGVEAQIVSVETGKYQPPNQLGEIWVRGPNMMKGYFNNPQATKETIDKKGWVHTGDLGYFNEDGNLYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDEEAGEVPIAFVVRPPNSSVSEEDIQKFIAKQVAPFKRLRRVSFINTVPKSAAGKILRRELIQKVKSKL
>Roisl.0091s0406.1.v1.1
MAATNLHISSNTKTPKSHQNPPFWFSPETGIYTSIFPSVHLPVDPNLDAVTALFSHRHDGDAALIDSLTGFSISHIELQSMVQSMAAGIYHNLGVQQGDTVSLILPNSVYFPIIFLSLLSLGVIVTTMNPSSSLGEIKKQVSECNVGLAFTSTENVEKLSSLGIIVIRVPESYDFDLIRIENPKFYSIVKGGFGFVPKPLIKQDDVAATMYSSGTTGASKGVLLTHRNLIATMELFVRFEASQYEYPGSSNVYLAALPLGHIYGLSLFVLGLLSLGSTIVVMRRFDASDVINVIERFKITHFPVVPPMLMALTKKAKGVCGEVFKSLKQVSSGAAPLSRKFIEDFLQTLPHVDLIQGYGMTESTAVGTRGFNSEKLRSYCSVGLLAPNMQAKVVDWSSGSFLPPGNRGELWIQGPGVMKGYLNNPEATQMIIVEDSWLRTGDIAYFDEDGYLFIVDRIKEIIKYKGFQIAPADLEAVLVSHPLIIDAAVTAAPNEECGEIPVAFVVRRQETTLSEQDVINYVAAQVAPYRKVRKVVMVSSIPKSPAGKILRKELKRVLANCVSSRL
>Roisl.0115s0466.1.v1.1
MSSQEVMINDQKQRSSEVIFRSKLPDIYIPNHLAFHDYIFQNISEFAAKPCLINGVTGEVYSYADVHVTSRKLAAGLQKLGVNQHDVVMLLLKNSPELVLTFLAVSFIGAITTAANPFFTPAEISKQSKSSAAKLIVTESKYVNKIKILQNDGVSIICTDDSSAIPEGCIRFSELTQSGEEEQNLETKISPDDVVQVDGENPNIYFHREDVILCVLPMFHIYAFNCIVLCSLRVGATILILPKFEIGLLLEQIQRFKVTVAMVVPPIVLAIVKSQETEKYDLSSVRIIRSGAAPFGKELEDAISAKFPNAKLGQGYGMTETGPIAMSLGFAKQPFPMKSGACGTVVSNAEMKIIDPTTGDSLPRNKSGEICIRGHQIMKGYLNDPVATASTIDKDGWLHTGDVGFVDDDDELFIIDRLKELIKYKGFQVAPAELESLLIAHPHINDVAVVAMKEEDAGEVPVAFVVRTKDSNISEDEIKLLVSKQVVFYKRINRVFFTDSIPKAPSGKILRKDLRARLANGLMK
>Roisl.0115s0465.1.v1.1
MVLQQQTLFLTKKTDQEPSHDFIFRSKLPDIFIPNHLPLIDYVFQRFSGDGDGDSTSTCLIDGSTGRVFTYADVQTNSRRIAAGIHRLGIGHRDVVMLLLPNSPEFALSFLAVAYLGAISTTANPFYMQPEIEKQAKASTAKLIITKRCYVDKLTNLKNDGVLIVCVEDGDDDVVSLDGRVSFTELIQADETELPKPDISPEDTVAMPYSSGTTGLPKGVMITHKGLVTSIAQKVDGDNPNLNFTADDVILCFLPMFHIYALDALMLSAMRTGAALLIVPRFELNLVMELIQRYKVTVVPVAPPVVLAFVKSPETERYDLSSVRMMLSGAATLKKELEEAVRLKFPNAIFGQGYGMTESGTVAKSLAFAKNPFKTKSGACGTVIRNAEMKVVDTVTGVSLPRNQSGEICVRGHQLMKGYLNDPEATARTIDKDGWLHTGDIGFVDDDDEIFIVDRLKELIKFKGYQVAPAELEALLISHPCIDDAAVVAMKDEVADEVPVAFVVRSEGSQLTEDDVKSYVNKQVVHYKRIKKVFFIEAIPKAVSGKILRKELRAKLETEYSK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University