Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Roridula gorgonias
Species name
Roridula gorgonias is a species of eudicot in the family Roridulaceae.
Species info
Gene sequence info
Roridula_gorgonias.4CL.fa
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>rgor_00559-RA
MLLLPNSPEFVFAFLGASYIGATTTMANPFFTAAEMLKQAKASNSKLVVTQASYVEKVKDYASENNVKVMCIDSPPAGFLHFSELTQSDEHEMPEVEISPTDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYIHSDDVMICVLPLFHIYSLNSVLLCGLRVGAAILIVPKFEIVSFLEMMKRYKVTIGPFVPPIVLAIAKSAAVDDYDLSAVRMVMSGAAPLGKELEEAARAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPETGASLPRNQPGEICIRGDQIMK
>rgor_01110-RA
YLNDPEATERTIDKDGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDESAGEVPVAFVLRSNGSKITEDEVKQYISKQVVFYKRINRVFFIDAIPKSPSGKILRKDLRARLAAGLPK
>rgor_06346-RA
KNTKMEKSGYGRDGIFRSLRPPLILPRDQNLSMVSFLFRNSYSYPDKPALVDAGSGETLTFAHFKSTVAKVSHGLLQLGIRKNDVVLIFSPNSIQFPLCFFGIIAIGAIATTVNPVYTVSELSKQIKDCNPKLIVTVPELFDKVKGFGIPSIFLGSEISNSTVNDSNSKVRLLIDLIKNSGSVSNLPEASIRSHDTAALLYSSGTTGMSKGVVLSHRNFVAAAMMVSADQDLAGEMHNVYLCVLPMFHVFGLAVIMYSQLQRGNAIVSMGKFDLGMVLRAVEKHRVTHLWVVPPIILALSKNSVVKKYDLSSLRQIGSGAAPLGKDLMAACAKNFPQAVLIQGYGMTETCGIVSVENQRAGPRHSGSAGMLVPGVESQIVGVDALKPLPPNQLGEIWVRGPNMMQGYFNNPEATRLTIDKQGWVRTGDLGYFDDEGQLFVVDRIKELIKCKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEEDVQKFIATQVAPFKRLRRVTFVSSVPKSVSGKILRRELIEKVRSKL
>rgor_06396-RA
YLNDPEATERTIDKEGRLHTGDIGNIDDEEEVFIVDRLKELINMKDEAAGEVPVAFVVRENASKITEDEIKQYISKQVVFYKRINRVFFTDTLPKASSGSNN
>rgor_15504-RA
MLSVASAETQNPELSPKGVTSAALAPEKNPSSPCETDHIFRSKLPEIPITNHLPLHTYCFENLSQFPDRTCLIVGSTGKSYSFAETHLVSRKVAAGLSNLGIGKGDVIMLLLQNCAEFVFAFMGASMIGAVTTTANPFYTAAEVFKQFTASKAQLIITHSQYVEKLRDAGDNFPKLGDDFTLITIDDPPENCHHFSVLSDANEAEMPCQPIDPDDAVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLHLKTEDMVLCVLPLFHIYSLNSVLLCSLRAGAGVLLMQKFEIGVLLELIQRHRVSVAAVVPPLVLALAKNPMVEGFDLSSIRMVLSGAAPLGKELEEALRSRVPQAVFGQGYGMTEAGPVLSMSLAFAKQPFPTKSGSCGTVVRNAELKVIDPETGSSLPHNEPGEICIRGHQIMKGYLNDADSTATTIDVDGWLHTGDIGYVDDDDEVFIVDRVPPAELEALLVSHPLIADAAVVPQKDDVAGEVPVAFVVRSNGFELTEEAVKEFIAKQVVFYKKLHRVYFVHAIPKSPSGKILRKDLRAKLATGSQIP
>rgor_17654-RA
MATQNMAQTEDHIFQSPYPSVPVPKNVTLPDFVLHDAELYANKVAFVEAASGKEYNYGQVLRDTRRFAKALRSLGLRNGRVVVVVLPNVAEYAIVALGIMAAGGVFSGANPSAHASEIKKQVEAADAKLIVTDGPNYDKVNSLGLPIIVLGEQQVESAMYWDELLEAADRANTDLITEPVNQTNLCALPFSSGTTGTSKGVMLTHRNLVANLCSTLFSVGPELIGRVTTLGLMPFFHIYGMTGICCATLRNKGKVVVMGRYKIDTFFSALIAHEVTFAPIVPAVILDMVKNPVVDEFDHGKLKLNAVMTAAAPLAPEVLTAFEKKYPGVDVQEAYGMTEHSCITLTHGDPNKGHRIAKKTSVGFILPNLELKFVDPNTGHSLPSNARGEIYVRSQCVMQGYYRNEDETARTIDENGWLHTGDIGYIDNDGDVFIVDRIKELIKYKGFQVAPAHLESILLTHPSIVDAAVIPLPDEEAGEIPAACVVMNKGAKESEGEIMKYVSSNVANYERVRVVRFVDAIPRSDSGKILRRLLKEEMIKKKGL
MLLLPNSPEFVFAFLGASYIGATTTMANPFFTAAEMLKQAKASNSKLVVTQASYVEKVKDYASENNVKVMCIDSPPAGFLHFSELTQSDEHEMPEVEISPTDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYIHSDDVMICVLPLFHIYSLNSVLLCGLRVGAAILIVPKFEIVSFLEMMKRYKVTIGPFVPPIVLAIAKSAAVDDYDLSAVRMVMSGAAPLGKELEEAARAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPETGASLPRNQPGEICIRGDQIMK
>rgor_01110-RA
YLNDPEATERTIDKDGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDESAGEVPVAFVLRSNGSKITEDEVKQYISKQVVFYKRINRVFFIDAIPKSPSGKILRKDLRARLAAGLPK
>rgor_06346-RA
KNTKMEKSGYGRDGIFRSLRPPLILPRDQNLSMVSFLFRNSYSYPDKPALVDAGSGETLTFAHFKSTVAKVSHGLLQLGIRKNDVVLIFSPNSIQFPLCFFGIIAIGAIATTVNPVYTVSELSKQIKDCNPKLIVTVPELFDKVKGFGIPSIFLGSEISNSTVNDSNSKVRLLIDLIKNSGSVSNLPEASIRSHDTAALLYSSGTTGMSKGVVLSHRNFVAAAMMVSADQDLAGEMHNVYLCVLPMFHVFGLAVIMYSQLQRGNAIVSMGKFDLGMVLRAVEKHRVTHLWVVPPIILALSKNSVVKKYDLSSLRQIGSGAAPLGKDLMAACAKNFPQAVLIQGYGMTETCGIVSVENQRAGPRHSGSAGMLVPGVESQIVGVDALKPLPPNQLGEIWVRGPNMMQGYFNNPEATRLTIDKQGWVRTGDLGYFDDEGQLFVVDRIKELIKCKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEEDVQKFIATQVAPFKRLRRVTFVSSVPKSVSGKILRRELIEKVRSKL
>rgor_06396-RA
YLNDPEATERTIDKEGRLHTGDIGNIDDEEEVFIVDRLKELINMKDEAAGEVPVAFVVRENASKITEDEIKQYISKQVVFYKRINRVFFTDTLPKASSGSNN
>rgor_15504-RA
MLSVASAETQNPELSPKGVTSAALAPEKNPSSPCETDHIFRSKLPEIPITNHLPLHTYCFENLSQFPDRTCLIVGSTGKSYSFAETHLVSRKVAAGLSNLGIGKGDVIMLLLQNCAEFVFAFMGASMIGAVTTTANPFYTAAEVFKQFTASKAQLIITHSQYVEKLRDAGDNFPKLGDDFTLITIDDPPENCHHFSVLSDANEAEMPCQPIDPDDAVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLHLKTEDMVLCVLPLFHIYSLNSVLLCSLRAGAGVLLMQKFEIGVLLELIQRHRVSVAAVVPPLVLALAKNPMVEGFDLSSIRMVLSGAAPLGKELEEALRSRVPQAVFGQGYGMTEAGPVLSMSLAFAKQPFPTKSGSCGTVVRNAELKVIDPETGSSLPHNEPGEICIRGHQIMKGYLNDADSTATTIDVDGWLHTGDIGYVDDDDEVFIVDRVPPAELEALLVSHPLIADAAVVPQKDDVAGEVPVAFVVRSNGFELTEEAVKEFIAKQVVFYKKLHRVYFVHAIPKSPSGKILRKDLRAKLATGSQIP
>rgor_17654-RA
MATQNMAQTEDHIFQSPYPSVPVPKNVTLPDFVLHDAELYANKVAFVEAASGKEYNYGQVLRDTRRFAKALRSLGLRNGRVVVVVLPNVAEYAIVALGIMAAGGVFSGANPSAHASEIKKQVEAADAKLIVTDGPNYDKVNSLGLPIIVLGEQQVESAMYWDELLEAADRANTDLITEPVNQTNLCALPFSSGTTGTSKGVMLTHRNLVANLCSTLFSVGPELIGRVTTLGLMPFFHIYGMTGICCATLRNKGKVVVMGRYKIDTFFSALIAHEVTFAPIVPAVILDMVKNPVVDEFDHGKLKLNAVMTAAAPLAPEVLTAFEKKYPGVDVQEAYGMTEHSCITLTHGDPNKGHRIAKKTSVGFILPNLELKFVDPNTGHSLPSNARGEIYVRSQCVMQGYYRNEDETARTIDENGWLHTGDIGYIDNDGDVFIVDRIKELIKYKGFQVAPAHLESILLTHPSIVDAAVIPLPDEEAGEIPAACVVMNKGAKESEGEIMKYVSSNVANYERVRVVRFVDAIPRSDSGKILRRLLKEEMIKKKGL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University