Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Ricinus communis
Species name
Castor bean (Ricinus communis) is a species of eudicot in the family Euphorbiaceae (spurge family).
Species info
Gene sequence info
Ricinus_communis.COMT.fa
Download
>rna-XM_002534943.2
MAWVLHDWNDDECIQILKKCKEAVPEDNGKVIIVEAVIGEAKDDKFEYVRLMLDIVIMAHTNTGKETTSKEWESVIQKAGFRSHTIKPIGAIYAVGFAANKDAIQKSNYMSSYNYLWILHDWNDDECIQILKKCKEAVPEDNGKVIIVEAVIGEVKDDKLEYVRLMLDMVMMAHTNTGKERTSKEWESVIQKAGFRSHTIKPIGAVQSIIEAFP
>rna-XM_002526786.3
MLTGIPTGEAIMIKDTCHNWRDEIVIRVLKNIYKMLPGNGKVIIMNAVLPEAAERSKSSQYVSRLDNTMLMQPGGKERTAKEFVLTQAAGFSNFRVACVARGIWAVMESFK
>rna-XM_002526781.3
MDSIMRRYQEEEEEEACLNAMLFSSSHVFPMVFSAAIELDLFGIIAKSGPGGAHVSASEIASHLPTKNPDAPSMIDRMLRLFANHSLLSSSLRTLHDGRVERLYGLTPACKFFLGSKEEQGSLAPLSALSTHPATVQVWLHMKEAILEGGNMFKKVHGISIFEYMKKDSEFNRIFNEAMAGLSTVIMNAILETYKGFEGITSLVDVGGGTGKVLHMIISKYPSIKGINFDLPHVIESAPPILGIQHVGGDMLTAIPTGEAIMIKDTCHNWSDEIVIQVLKNIYKMLPGNGKLIIMNAVLPEAAERSKSSQYVSRLDNTMLMQPAGKERTAKEFEFLTQAAGFSNFRVACVARGIWAVMESFK
>rna-XM_002525772.3
MGSTGETQMTPTQVSDEEANLFAMQLASASVLPMVLKSAIELDLLEIMAKAGPSAFLSPSEIASQLPTKNPDAPVMLDRILRLLASYNVLTCSLRTLPDGKVERLYGLAPVCKFLIKNEDGVSIAPLCLMNQDKVLMESWYYLKDAVLLGGIPFNKAYGMTAFDYHGTDPRFNKVFNRGMSDHSTITMKKILETYKGFEGLTSVVDVGGGTGAVLSMIVSKYPSIKGTNFDLPHVIEDAPSFPGVEHVGGDMFASVPKGDAIFMKWICHDWSDEHCLNFLKNCYDALPANGKVIVAECILPVAPDSSLATKGVIHIDCIMLAHNPGGKERTEKEFEALAKGAGFQGFQVMCCAFNSYVMEFLKKA
>rna-XM_002520246.3
MSDPNQEEETGKLAIRLANAVVLPMVLKSALELNVIDIISIATSSGGASLSPSEIASKIPTENPDAPILLDRMLRLLASYDILHCSLVTKENGEVERLYSAKPICKFLVINEGQERSVAPLFLLHHDEVFMKSCYHFNDAIIEGGVPFKRAYGMIGFEYLGTDQRFKRVFNQAMSNHTTLIMKKILDVYKGFEGLKVLVDVGGGVGVTLNIIISNYPEIKGINFDLPHVLADAPSYAGVEHVGGDMFVSVPKGDAIFMKWILHGWSDEHCLKLLKKCWEALPNNGKVIVVESILPVAPEKIVSSHIVFEQDLFMLAQTAGGKERTQKEFEVLALRSGFSCCQVICCAYNSWVMEFHKRE
>rna-XM_002520245.3
MSNPNQEEETGKLAIRLANAVVLPMVLKSALELNVIDIISTATSSGGASLSPSEIAARIPTENPDAPILLDRMLRLLASYDILNCSLVTKDNGKVERLYSAKPICKFLTINQSQEGSVAPLFLLHHDEVFMKSWYHFNDAILEGGIPFNRAYGMTAFEYPGTDQRFNRVFNQAMSNHTTLIMKKILDVYKGFEGLNVLVDVGGGVGVALNIITSKYPEIRGISFDLPHVLADAPSYAGVEHVGGDMFVSVPKGDAIFMKWILHDWSDEHCLKLLKNCWEALPNNGKVIVVESILPVAPENIVSSHIVFEQDLFMLAQNPGGKERTKKEFEALALRSGFSCYEVICCAYNSWVMEFHKENDL
>rna-XM_002519380.3
MENESSETRKNAKLAIIELANMISVPMSLNAVVQLNVADAIWQNGVNSPLSASEILSRINLSGGDPDNLQRILRMLSSYNVFTEHLSAVDGVTERRYSLTEIGKTLVTDVNGLSYGAYVLQHHQDALMRAWPLVHEAVLDSTTEPFAKANGEPAYDYYGKRPEMNELMQKAMSGLSVPFMKAVLNGYDGFQGVEKIVDVGGSAGDCLKTILQKYPNVREGINFDLPEVVAKAPNIPGVTHVGGDMFKSVPSADAIFMKWILTTWTDDECKVIMENCYKALPVGGKLIACEPVLPNQTDDSHRTRALLEGDIFVMTIYRAKGKHRTEEEFKKLGHSVGFSHFRPLYFDHFHTVLEFQK
>rna-XM_015718970.2
MSXXPMALRASIELGVFEIIEKAGQGALLSPS*IALQIATLDNPEAPFVLDRILSLLASHCILTCSSQGGQFHRLYGLAPVAKYFIKNQDGGWLTPFLMMIQDKFIMDIWYHLKDAVVEGGIPFDRAHGINAMEYMGKDARFSQIFKASMRDFDPLLMQTILDKYDGFVGLKSLVDVGGGDGSILNMILSKYPSIKGINYDLPQIIEKSPSYPGIEHVAGDMFMSIPKGEAIFMKWILHGWDDLDCLKLLKNCYETLPSNGKVIAVDLVVPAAPGTSAAARSLLQSYLYMTSMNPKGQERTEMQFQSLAKQAGFSHVQVACYAYTFSVVEFHKII
>rna-XM_002515041.3
MASSAETRLHPIDEEHDENFGYAMQLALGSALPMSLHAAIELGVFEIIAKAGPESKLSASEITAEIPDVQNPDAAITLDRVLRLLASHNVLGCSLNGLERLYSLNPVSKYFVPNQDGISLGPFMALIQDKVFLDSWTKLKDAVLEGGSPFNKFHGTHCFGYSGLDSRFNHVFNTAMFHHTNLVITKILETYKGFKQLKQLIDVGGGLGHTLKAIISKYPHLKGINFDLPHVVKYAPAIPGVEHVAGDMFESVPKGEAIFMKWILHDWSDEHCLRLLKNCYEALPDDGKVIVMDAVLPVMPETGKAAKANFQTDLVVMTVYEGGTERTEHEFLAMATAAGFRGIRYVCCACNFWIMEFFK
>rna-XM_002513043.2
MDTVKNLQASNVPSSLSQEDEEVFTSGLHVCSSEVFSHALSNCIQLGLFDIIAEAGPSAYLTATEITAQLPTKNPDAVSMIDRMLRLFSCHSLLNSSLKTVADDVVETRYGLSPIGHLFVRKKDGVTMAACFTDYKAWTEAWLHLKDAILEGGNPYEKAHGVPIYEHISSDTESVKGFSQAMDSISSFIMKKVLENYSGFKGLGSLVDVGGGSGFALNMITSEYPSISCINFDLPHVVQEAPYHPGVKHVGGDMFLDIPSADAIMIKEVLHNWGNEDCVKVLKNCYEALPKGGKVIVVSHVMPEVVGSSNAAAKYVCQLDVMMLLFGGGKERTEKEFKALGKAAGFSGFQLICFAAYNAVAVMEFYK
MAWVLHDWNDDECIQILKKCKEAVPEDNGKVIIVEAVIGEAKDDKFEYVRLMLDIVIMAHTNTGKETTSKEWESVIQKAGFRSHTIKPIGAIYAVGFAANKDAIQKSNYMSSYNYLWILHDWNDDECIQILKKCKEAVPEDNGKVIIVEAVIGEVKDDKLEYVRLMLDMVMMAHTNTGKERTSKEWESVIQKAGFRSHTIKPIGAVQSIIEAFP
>rna-XM_002526786.3
MLTGIPTGEAIMIKDTCHNWRDEIVIRVLKNIYKMLPGNGKVIIMNAVLPEAAERSKSSQYVSRLDNTMLMQPGGKERTAKEFVLTQAAGFSNFRVACVARGIWAVMESFK
>rna-XM_002526781.3
MDSIMRRYQEEEEEEACLNAMLFSSSHVFPMVFSAAIELDLFGIIAKSGPGGAHVSASEIASHLPTKNPDAPSMIDRMLRLFANHSLLSSSLRTLHDGRVERLYGLTPACKFFLGSKEEQGSLAPLSALSTHPATVQVWLHMKEAILEGGNMFKKVHGISIFEYMKKDSEFNRIFNEAMAGLSTVIMNAILETYKGFEGITSLVDVGGGTGKVLHMIISKYPSIKGINFDLPHVIESAPPILGIQHVGGDMLTAIPTGEAIMIKDTCHNWSDEIVIQVLKNIYKMLPGNGKLIIMNAVLPEAAERSKSSQYVSRLDNTMLMQPAGKERTAKEFEFLTQAAGFSNFRVACVARGIWAVMESFK
>rna-XM_002525772.3
MGSTGETQMTPTQVSDEEANLFAMQLASASVLPMVLKSAIELDLLEIMAKAGPSAFLSPSEIASQLPTKNPDAPVMLDRILRLLASYNVLTCSLRTLPDGKVERLYGLAPVCKFLIKNEDGVSIAPLCLMNQDKVLMESWYYLKDAVLLGGIPFNKAYGMTAFDYHGTDPRFNKVFNRGMSDHSTITMKKILETYKGFEGLTSVVDVGGGTGAVLSMIVSKYPSIKGTNFDLPHVIEDAPSFPGVEHVGGDMFASVPKGDAIFMKWICHDWSDEHCLNFLKNCYDALPANGKVIVAECILPVAPDSSLATKGVIHIDCIMLAHNPGGKERTEKEFEALAKGAGFQGFQVMCCAFNSYVMEFLKKA
>rna-XM_002520246.3
MSDPNQEEETGKLAIRLANAVVLPMVLKSALELNVIDIISIATSSGGASLSPSEIASKIPTENPDAPILLDRMLRLLASYDILHCSLVTKENGEVERLYSAKPICKFLVINEGQERSVAPLFLLHHDEVFMKSCYHFNDAIIEGGVPFKRAYGMIGFEYLGTDQRFKRVFNQAMSNHTTLIMKKILDVYKGFEGLKVLVDVGGGVGVTLNIIISNYPEIKGINFDLPHVLADAPSYAGVEHVGGDMFVSVPKGDAIFMKWILHGWSDEHCLKLLKKCWEALPNNGKVIVVESILPVAPEKIVSSHIVFEQDLFMLAQTAGGKERTQKEFEVLALRSGFSCCQVICCAYNSWVMEFHKRE
>rna-XM_002520245.3
MSNPNQEEETGKLAIRLANAVVLPMVLKSALELNVIDIISTATSSGGASLSPSEIAARIPTENPDAPILLDRMLRLLASYDILNCSLVTKDNGKVERLYSAKPICKFLTINQSQEGSVAPLFLLHHDEVFMKSWYHFNDAILEGGIPFNRAYGMTAFEYPGTDQRFNRVFNQAMSNHTTLIMKKILDVYKGFEGLNVLVDVGGGVGVALNIITSKYPEIRGISFDLPHVLADAPSYAGVEHVGGDMFVSVPKGDAIFMKWILHDWSDEHCLKLLKNCWEALPNNGKVIVVESILPVAPENIVSSHIVFEQDLFMLAQNPGGKERTKKEFEALALRSGFSCYEVICCAYNSWVMEFHKENDL
>rna-XM_002519380.3
MENESSETRKNAKLAIIELANMISVPMSLNAVVQLNVADAIWQNGVNSPLSASEILSRINLSGGDPDNLQRILRMLSSYNVFTEHLSAVDGVTERRYSLTEIGKTLVTDVNGLSYGAYVLQHHQDALMRAWPLVHEAVLDSTTEPFAKANGEPAYDYYGKRPEMNELMQKAMSGLSVPFMKAVLNGYDGFQGVEKIVDVGGSAGDCLKTILQKYPNVREGINFDLPEVVAKAPNIPGVTHVGGDMFKSVPSADAIFMKWILTTWTDDECKVIMENCYKALPVGGKLIACEPVLPNQTDDSHRTRALLEGDIFVMTIYRAKGKHRTEEEFKKLGHSVGFSHFRPLYFDHFHTVLEFQK
>rna-XM_015718970.2
MSXXPMALRASIELGVFEIIEKAGQGALLSPS*IALQIATLDNPEAPFVLDRILSLLASHCILTCSSQGGQFHRLYGLAPVAKYFIKNQDGGWLTPFLMMIQDKFIMDIWYHLKDAVVEGGIPFDRAHGINAMEYMGKDARFSQIFKASMRDFDPLLMQTILDKYDGFVGLKSLVDVGGGDGSILNMILSKYPSIKGINYDLPQIIEKSPSYPGIEHVAGDMFMSIPKGEAIFMKWILHGWDDLDCLKLLKNCYETLPSNGKVIAVDLVVPAAPGTSAAARSLLQSYLYMTSMNPKGQERTEMQFQSLAKQAGFSHVQVACYAYTFSVVEFHKII
>rna-XM_002515041.3
MASSAETRLHPIDEEHDENFGYAMQLALGSALPMSLHAAIELGVFEIIAKAGPESKLSASEITAEIPDVQNPDAAITLDRVLRLLASHNVLGCSLNGLERLYSLNPVSKYFVPNQDGISLGPFMALIQDKVFLDSWTKLKDAVLEGGSPFNKFHGTHCFGYSGLDSRFNHVFNTAMFHHTNLVITKILETYKGFKQLKQLIDVGGGLGHTLKAIISKYPHLKGINFDLPHVVKYAPAIPGVEHVAGDMFESVPKGEAIFMKWILHDWSDEHCLRLLKNCYEALPDDGKVIVMDAVLPVMPETGKAAKANFQTDLVVMTVYEGGTERTEHEFLAMATAAGFRGIRYVCCACNFWIMEFFK
>rna-XM_002513043.2
MDTVKNLQASNVPSSLSQEDEEVFTSGLHVCSSEVFSHALSNCIQLGLFDIIAEAGPSAYLTATEITAQLPTKNPDAVSMIDRMLRLFSCHSLLNSSLKTVADDVVETRYGLSPIGHLFVRKKDGVTMAACFTDYKAWTEAWLHLKDAILEGGNPYEKAHGVPIYEHISSDTESVKGFSQAMDSISSFIMKKVLENYSGFKGLGSLVDVGGGSGFALNMITSEYPSISCINFDLPHVVQEAPYHPGVKHVGGDMFLDIPSADAIMIKEVLHNWGNEDCVKVLKNCYEALPKGGKVIVVSHVMPEVVGSSNAAAKYVCQLDVMMLLFGGGKERTEKEFKALGKAAGFSGFQLICFAAYNAVAVMEFYK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University