Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Ricinus communis
Species name
Castor bean (Ricinus communis) is a species of eudicot in the family Euphorbiaceae (spurge family).
Species info
Gene sequence info
Ricinus_communis.4CL.fa
Download
>rna-XM_002533140.3
MEDAKIDNNTNNNIHHQEFIFRSKLPDIYIPNHLPLHTYCFENISQFKDNACLINGATGDVYTYADVELTSRKVAAGLHKLGIKQNEVIMILLQNSPEFVFAFLGASVLGAISTTANPFYTPAEIKKQASASNAKLIITQAAYVEKVKDFANENGIKIMTIDSPPPALDDCRDCLHFSELTKADENDIPAVKINPDDVVALPYSSGTTGLPKGVMLTHKSLVTSVAQQVDGENPNLYFHEKDVILCLLPLFHIYSLNSVLLCGLRVGAAILIMQKFEITALMELVQKYKVTIAPFVPPIVLSIAKSPAVDKYDLSSIRTVMSGAAPMGKELEDTVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDTGKSLQRNQAGEICIRGSQIMKGYLNDPEATERTIDKEGWLHTGDVGYIDGDDELFIVDRLKELIKYNGFQVAPAELEAMLIAHPSISDAAVVPMKDEAAGEIPAAFVVRSNGSKITEDDVQQYISKQVIYYKRIRRVFFTDSIPKAPSGKILRKDLRARLAAGVPT
>rna-XM_002523652.3
MEKSGYGRDGIYRSLRPLLVLPKDPNLSMVSFLFRNCNSYPHKPALIDADLSKTLSFSQLKSIVIKVSHGLLKLGISKNDVVLIFAPNSYQFPICFLAITSIGAIATTANPLYTTTEISKQIKDSNPKLVITVPELWNKVKDFNLPAVFLGAKESLLIEPNSRIKSFDHLVELGGSNSEFPTINVKQTDIATLLYSSGTTGISKGVILTHGNFIAASQMITMDQEIAGELHNVFLCFLPMFHVFGLAVIAYSQLQTGNAVVSMGKFDFELVLKAVEKYRITHLWVVPPVILALAKQSLVKKYDLSSLQHVGSGAAPLSKELMEECAKTIPHAAIAQGYGMTETTGIVSVENPRIGVRHSGSAGTLAAGIEAQIISVDTLKPLPPNQLGEIWVRGPNMMRGYFNNPQATKQTIDKKGWLHTGDLGYFDEDGKLYVVDRIKELIKYKGFQVAPAELEGLLVSHPELLDAVVIPFPDAEAGEVPVAYVVRSPNSSLTEEEVQKYIADQVAPFKRLRRVTFINTVPKSASGKILRRELIEKVKSKL
>rna-XM_002519982.3
MISIASLEPPKQELSSSSSSQKQNPSSSSSETHIFRSKLPDIPISNHLPLHTYCFENLFKLSDKPCLISGSTGKTYSFAETHLISQKTAAGLSSLGIKKGDVIMILLQNCPEFVFSFMGASMIGAVATTANPFYTSNEIFKQLNSSRPKLIITQSLYVDKLRDPDHKIQPKLGEDFTVITIDEPPENCLHFTVLSEASETEIPEVINANPDDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLKEDDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMQKFQIGALLELIQKHKVSVAAVVPPLVLALAKNPMVAEFDLSSIRVVLSGAAPLGKELEDALRSRVPQAILGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPETGCSLGYNQPGEICIRGPQIMKGYLNDPEATANTIDVEGWLHTGDIGYVDDDDEIFIVDRVKEIIKFKGFQVPPAELEALLLNHPSIADAAVVPQKDEVAGEVPVAFVVRSNGFELSEEDVKEYIAKQVVFYKKLHKVYFIHAIPKSPSGKILRKDLKAKLATPSPLS
>rna-XM_002519441.3
MPRSYNPNTKTYISPRPPIHLPTDPNLSLTSFLFNSTLSVPHSTALIDSDSNETLTFHDLRIRVSKLAQALLNLNIAKNDVVLILSPNSIHFPVIFLAIVSIGAIASTCNPSYTISELSKQVTDCNPKLIITVPQLITKVKHFNLPLILLNSPDSTHLISNPKIWNYSDLIKSLSSEVLNLPVNNVQQSDVAALFYSSGTTGTSKGVILTHRNFIATSLMVTADQDRYNEPKNVFLCFLPMFHIFGFAVTTYAQLRRGNSVVSMEKFELDKMLRSIEKYRVSYLFVVPPVVIALAKQNVVEKFDLTSLKVIGSGAAPLGKDIMEECAKNLPHVEIVQGYGMTETCGIISIEDRKEGIRLSGSTGLLVPGVESQIISVDTAKPLPPNQLGEICLRGANMMEGYFNNPQATNLTIDEQAWVHTGDLGYFNAEGHLFVVDRIKELIKCYGFQVAPAELEGLLLLHPEILDAVVIPFPDPKAGEVPIAYVVRSPNSSLTEEDVQKFIAEQVAPFKRLQGDIHKQCPKVSFRKNFEKRTD
>rna-XM_002514858.3
MARSLLRYLSLNNFPSSCQKHDYQISIFPCSFKAHPNPALFPCHISIMETLHQEHIFRSRFPPVPVPEDATIPDFVLQDAELYADKVAFVEAVTGKAYTYSEVVKETRRFAKALRSIGLRKGQVVIVVLPNVAEYGIVVLGIMAAGGVFSGANPTGLESEIKKQAEAANAKLIVTNDAHYGKVKGLELPVIVLGETSNANAMNWTELLNAADRASDKSVHEVIHQTDLCALPFSSGTTGISKGVMLTHRNLVANLCSSLFSVGPEMIGQVTTLGLIPFFHIYGITGICFATLRNKGKVVVVNRFELRTFLHALITQEVTFAPIVPPIILTLVKDPVVEEFDLTKLKLRAIMTAAAPLAPDLLTAFEKKFPGVQVQEAYGMTEHSCITLTHGDPDKGHGIAKKNSVGFILPNLEVKFIDPDTGLSLPKNTPGEVCVRSQCVMIGYYNNKEETSRTIDKDGWLHTGDIGYIDDDGDMFIVDRIKELIKFKGFQVAPAELEAVLLGHPSVEDAAVVPLPDEEAGEIPAACVVINQEAKESEEDILNYVADNVAHYKKVRVVQFVDTIPKSQSGKIMRRLLKEKMVEKMKANSNVQDKKVLPK
>rna-XM_002512735.3
MENSQVKQQEDIVFRSKLPDIYIPKNLSLHSYIFQNISDYSSKPCLINGATGRVYTYAEVEITSRRVASGLNKLGVKQGEVIMLLLHNSPEFVLSFLGASYRGAIATAANPLFTSAEIAKQAKASNTKLIITQAAYADKVKELAIDHDIKIVCIDSAPDGCLHFSELSEADEKDLPEVDIVPEDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSEDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFDINLLLQLIEKHKVTVAPIVPPIVLAIAKSPETDKYDLSSIRMLKSGAAPLGKELEDTVRAKFPTAILGQGYGMTEAGPVLAMCLAFAKEPFDIKAGACGTVVRNAEMKIVDPETGDSLPRNQPGEICIRGDQIMKGYLNDPEATANTIDKQGWLHTGDIGYIDDDDELFIVDRLKELIKYKGYQVAPAELEAMLLAHPDILDAAVVAMKDEGAGEVPVAFVVRPDKSNITEDEIKQYIYKQVVFYKRISRVFFVEAIPKAPSGKILRKNLREKLAAGFQN
MEDAKIDNNTNNNIHHQEFIFRSKLPDIYIPNHLPLHTYCFENISQFKDNACLINGATGDVYTYADVELTSRKVAAGLHKLGIKQNEVIMILLQNSPEFVFAFLGASVLGAISTTANPFYTPAEIKKQASASNAKLIITQAAYVEKVKDFANENGIKIMTIDSPPPALDDCRDCLHFSELTKADENDIPAVKINPDDVVALPYSSGTTGLPKGVMLTHKSLVTSVAQQVDGENPNLYFHEKDVILCLLPLFHIYSLNSVLLCGLRVGAAILIMQKFEITALMELVQKYKVTIAPFVPPIVLSIAKSPAVDKYDLSSIRTVMSGAAPMGKELEDTVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDTGKSLQRNQAGEICIRGSQIMKGYLNDPEATERTIDKEGWLHTGDVGYIDGDDELFIVDRLKELIKYNGFQVAPAELEAMLIAHPSISDAAVVPMKDEAAGEIPAAFVVRSNGSKITEDDVQQYISKQVIYYKRIRRVFFTDSIPKAPSGKILRKDLRARLAAGVPT
>rna-XM_002523652.3
MEKSGYGRDGIYRSLRPLLVLPKDPNLSMVSFLFRNCNSYPHKPALIDADLSKTLSFSQLKSIVIKVSHGLLKLGISKNDVVLIFAPNSYQFPICFLAITSIGAIATTANPLYTTTEISKQIKDSNPKLVITVPELWNKVKDFNLPAVFLGAKESLLIEPNSRIKSFDHLVELGGSNSEFPTINVKQTDIATLLYSSGTTGISKGVILTHGNFIAASQMITMDQEIAGELHNVFLCFLPMFHVFGLAVIAYSQLQTGNAVVSMGKFDFELVLKAVEKYRITHLWVVPPVILALAKQSLVKKYDLSSLQHVGSGAAPLSKELMEECAKTIPHAAIAQGYGMTETTGIVSVENPRIGVRHSGSAGTLAAGIEAQIISVDTLKPLPPNQLGEIWVRGPNMMRGYFNNPQATKQTIDKKGWLHTGDLGYFDEDGKLYVVDRIKELIKYKGFQVAPAELEGLLVSHPELLDAVVIPFPDAEAGEVPVAYVVRSPNSSLTEEEVQKYIADQVAPFKRLRRVTFINTVPKSASGKILRRELIEKVKSKL
>rna-XM_002519982.3
MISIASLEPPKQELSSSSSSQKQNPSSSSSETHIFRSKLPDIPISNHLPLHTYCFENLFKLSDKPCLISGSTGKTYSFAETHLISQKTAAGLSSLGIKKGDVIMILLQNCPEFVFSFMGASMIGAVATTANPFYTSNEIFKQLNSSRPKLIITQSLYVDKLRDPDHKIQPKLGEDFTVITIDEPPENCLHFTVLSEASETEIPEVINANPDDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLKEDDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMQKFQIGALLELIQKHKVSVAAVVPPLVLALAKNPMVAEFDLSSIRVVLSGAAPLGKELEDALRSRVPQAILGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPETGCSLGYNQPGEICIRGPQIMKGYLNDPEATANTIDVEGWLHTGDIGYVDDDDEIFIVDRVKEIIKFKGFQVPPAELEALLLNHPSIADAAVVPQKDEVAGEVPVAFVVRSNGFELSEEDVKEYIAKQVVFYKKLHKVYFIHAIPKSPSGKILRKDLKAKLATPSPLS
>rna-XM_002519441.3
MPRSYNPNTKTYISPRPPIHLPTDPNLSLTSFLFNSTLSVPHSTALIDSDSNETLTFHDLRIRVSKLAQALLNLNIAKNDVVLILSPNSIHFPVIFLAIVSIGAIASTCNPSYTISELSKQVTDCNPKLIITVPQLITKVKHFNLPLILLNSPDSTHLISNPKIWNYSDLIKSLSSEVLNLPVNNVQQSDVAALFYSSGTTGTSKGVILTHRNFIATSLMVTADQDRYNEPKNVFLCFLPMFHIFGFAVTTYAQLRRGNSVVSMEKFELDKMLRSIEKYRVSYLFVVPPVVIALAKQNVVEKFDLTSLKVIGSGAAPLGKDIMEECAKNLPHVEIVQGYGMTETCGIISIEDRKEGIRLSGSTGLLVPGVESQIISVDTAKPLPPNQLGEICLRGANMMEGYFNNPQATNLTIDEQAWVHTGDLGYFNAEGHLFVVDRIKELIKCYGFQVAPAELEGLLLLHPEILDAVVIPFPDPKAGEVPIAYVVRSPNSSLTEEDVQKFIAEQVAPFKRLQGDIHKQCPKVSFRKNFEKRTD
>rna-XM_002514858.3
MARSLLRYLSLNNFPSSCQKHDYQISIFPCSFKAHPNPALFPCHISIMETLHQEHIFRSRFPPVPVPEDATIPDFVLQDAELYADKVAFVEAVTGKAYTYSEVVKETRRFAKALRSIGLRKGQVVIVVLPNVAEYGIVVLGIMAAGGVFSGANPTGLESEIKKQAEAANAKLIVTNDAHYGKVKGLELPVIVLGETSNANAMNWTELLNAADRASDKSVHEVIHQTDLCALPFSSGTTGISKGVMLTHRNLVANLCSSLFSVGPEMIGQVTTLGLIPFFHIYGITGICFATLRNKGKVVVVNRFELRTFLHALITQEVTFAPIVPPIILTLVKDPVVEEFDLTKLKLRAIMTAAAPLAPDLLTAFEKKFPGVQVQEAYGMTEHSCITLTHGDPDKGHGIAKKNSVGFILPNLEVKFIDPDTGLSLPKNTPGEVCVRSQCVMIGYYNNKEETSRTIDKDGWLHTGDIGYIDDDGDMFIVDRIKELIKFKGFQVAPAELEAVLLGHPSVEDAAVVPLPDEEAGEIPAACVVINQEAKESEEDILNYVADNVAHYKKVRVVQFVDTIPKSQSGKIMRRLLKEKMVEKMKANSNVQDKKVLPK
>rna-XM_002512735.3
MENSQVKQQEDIVFRSKLPDIYIPKNLSLHSYIFQNISDYSSKPCLINGATGRVYTYAEVEITSRRVASGLNKLGVKQGEVIMLLLHNSPEFVLSFLGASYRGAIATAANPLFTSAEIAKQAKASNTKLIITQAAYADKVKELAIDHDIKIVCIDSAPDGCLHFSELSEADEKDLPEVDIVPEDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSEDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFDINLLLQLIEKHKVTVAPIVPPIVLAIAKSPETDKYDLSSIRMLKSGAAPLGKELEDTVRAKFPTAILGQGYGMTEAGPVLAMCLAFAKEPFDIKAGACGTVVRNAEMKIVDPETGDSLPRNQPGEICIRGDQIMKGYLNDPEATANTIDKQGWLHTGDIGYIDDDDELFIVDRLKELIKYKGYQVAPAELEAMLLAHPDILDAAVVAMKDEGAGEVPVAFVVRPDKSNITEDEIKQYIYKQVVFYKRISRVFFVEAIPKAPSGKILRKNLREKLAAGFQN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University