Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Rhododendron williamsianum
Species name
Rhododendron williamsianum is a species of eudicot in the family Ericaceae (heath family).
Species info
Gene sequence info
Rhododendron_williamsianum.4CL.fa
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>C3L33_00441-RA
MERYKVTYGPFVPPIVLAVAKCEKTDDYDLSAVRMVQSGAAPLGKEVEEAVRAKFRNATLVAPAELEALLLNHPEISDAAVVGMKDESAGEVPVAFVVKSNGSKITEEEVKQYISKQVVFYKRISRVFFNDAIPKAPSGKILRKDLRAKLAAGLPN
>C3L33_05642-RA
MWWPAVLVGDHWAAQGRYAHAQGVDGDNPNLYFHSEDVIMCVLPLFHIYSLNSVLLCALRVGAAILIMQKFEINALLELVHKYRVTIAPFVPPIVLAIAKSPVVDNYDLSSIRTVMSGAAPMGKELEDKYSETFAAQGYGMTEAGPVLSMCLAFAKEPFEIKSGSCGTVVRNAEMKIIDPDTGNSLPRNQAGEICIRGDQIMKGTIYYH
>C3L33_05641-RA
MLIAHPNISDAAVVPMKDEGAGEVPVAFVVRANGSKINEDEIKQYISKQVVFYKRINRVSSLIQSLKLHRAKYSEKTLERSSQLVFPINPYICYIL
>C3L33_16288-RA
MLEVASVETQKPELSPANLEITNSHQNQNQSSSSSSSETHNYVFRSKLPDIPISNHLPLHTYCFENISQFSDRACLILGSTNKTYSFAETHLISQKVAAGLSNLGLQKGDVIMLLLQNCAEFVFSFMGASMIGAVTTTANPFYTPAEVFKQFNASKAKLIITHSQYVDKLRDAGDNFPKLGEDFTLITIDDPPENCLHFSVLSEANETEIPTVSIDSNDAVALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLFLKTEDVVLCVLPLFHIFSLNSVLLCSLRAGSGVLLMQKFEIGALLELIQRYRVSVAAVVPPLVLALAKNPMVEGFDLSSIRTVLSGAAPLGKELEQALRSRVPQAVFGQGYGMTEAGPVLSMSLAFAKQPFQTKSGSCGTVVRNAELKVIDPETGSSLPHNQPGEICIRGLQIMKGYLNDDDATAATIDVDGWLHTGDIGYIDDDDEVFIVDRVKELIKFKGFQACYFVPPAELEALLVSHPSIADAAVVSQKDEVAGEVPVAFVVRSHGFELTEEAVKEFIAKQVVFYKRLHRVYFVHAIPKSPSGKILRKDLRAKLATAAVSHDIPS
>C3L33_13378-RA
MGLEISCQIELWKPVIAFLTAEASGGIVSLFRLTDKSPLGTTGKFKGVELTHRNFISSLAGFQAVRTVRSSPAVTLCAVPYFHVYGFVYSVRSVAMGENLVSIGKFDLVQMIKAIEGFRVTHVAVAPPVIVSMVNAYGLTESTAGISRMVGPNESQKFGASGRLVPYCQAKIVDVETGMDLPPFKQGELWXRGPSIMKGNFVIHSHVSSFNFQIFNVXYVGDPEATSAILDSEGWLRTGDLCYFDSEGFLYVVDRLKELIKYKGYQVT
>C3L33_13347-RA
MATLLQNQAQDQDHIFRSPYASIPVPDDVTLPEFVLQGFELYADRVAFVENESGKEYTHGEVVRETKRFAKALRSLGLRNGRVVVVLLPNVAEYAIVALGIMAAGGVFSGANPSGHASEIKKQVEAADARLIVTNGPNYEKVKGLGVPIIVLGEQRVESAIYWEELLEAADRASNGTITEPIAQTDLCALPFSSGTTGTSKGVMITHRNLISNLCSTLFSVRPELIGKVTTLGLMPFFHIYGLAGICCATLKNKGKVVVMGRYKIDTYLNALIDHEVTFAPIVPAIISDMVKILKNAAVDDFDLGKIKLHAVMTAAAPLAPEAYGMTEHSCITLTHGDPEKGHRIAKKNSVGFVLPNLEVKFIDPNTGRSLPKNTRGEICVRSQCVMKGYYKNKEETAQTIDENGWLHTGDIGYIDDDGDVFIVDRIKELIKYKGFQVAPAHLENIILTHPSVADAAVIPLPDEEAGEIPAACVVMDSNAKESEEDIMKYVASNVASYERVRVVQFVGAIPRSASGKILRRVLKEEMVKNMIIKTNPKLVRHC
>C3L33_13377-RA
MTLSILYLALFSLSVFISPSNPNAPESCQIELWKPVIAFVTAEASGGVVLLFWRTVLLDSLEFDSMMTTRSEEFFRFNIGTTGKFKGVELTHRNFISSLXGGQAVQTMRPSPAVTLCAVPYFHVYGFLYSMRTVAMGESLVSIGKFDLVQMIKAIEGFRVTHVAVAPPVIVSMVNVCDWTNGHDLSSLEVVVSAGAPLTKALIERFKKRFPRVQLPQAYGLTESTAVISRMVGPNESQKFGASGRLVPYCQAKIVDASGGIVSLFWRTVLLDSLEFDSMMTTRSKEFFRFNIG
MERYKVTYGPFVPPIVLAVAKCEKTDDYDLSAVRMVQSGAAPLGKEVEEAVRAKFRNATLVAPAELEALLLNHPEISDAAVVGMKDESAGEVPVAFVVKSNGSKITEEEVKQYISKQVVFYKRISRVFFNDAIPKAPSGKILRKDLRAKLAAGLPN
>C3L33_05642-RA
MWWPAVLVGDHWAAQGRYAHAQGVDGDNPNLYFHSEDVIMCVLPLFHIYSLNSVLLCALRVGAAILIMQKFEINALLELVHKYRVTIAPFVPPIVLAIAKSPVVDNYDLSSIRTVMSGAAPMGKELEDKYSETFAAQGYGMTEAGPVLSMCLAFAKEPFEIKSGSCGTVVRNAEMKIIDPDTGNSLPRNQAGEICIRGDQIMKGTIYYH
>C3L33_05641-RA
MLIAHPNISDAAVVPMKDEGAGEVPVAFVVRANGSKINEDEIKQYISKQVVFYKRINRVSSLIQSLKLHRAKYSEKTLERSSQLVFPINPYICYIL
>C3L33_16288-RA
MLEVASVETQKPELSPANLEITNSHQNQNQSSSSSSSETHNYVFRSKLPDIPISNHLPLHTYCFENISQFSDRACLILGSTNKTYSFAETHLISQKVAAGLSNLGLQKGDVIMLLLQNCAEFVFSFMGASMIGAVTTTANPFYTPAEVFKQFNASKAKLIITHSQYVDKLRDAGDNFPKLGEDFTLITIDDPPENCLHFSVLSEANETEIPTVSIDSNDAVALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLFLKTEDVVLCVLPLFHIFSLNSVLLCSLRAGSGVLLMQKFEIGALLELIQRYRVSVAAVVPPLVLALAKNPMVEGFDLSSIRTVLSGAAPLGKELEQALRSRVPQAVFGQGYGMTEAGPVLSMSLAFAKQPFQTKSGSCGTVVRNAELKVIDPETGSSLPHNQPGEICIRGLQIMKGYLNDDDATAATIDVDGWLHTGDIGYIDDDDEVFIVDRVKELIKFKGFQACYFVPPAELEALLVSHPSIADAAVVSQKDEVAGEVPVAFVVRSHGFELTEEAVKEFIAKQVVFYKRLHRVYFVHAIPKSPSGKILRKDLRAKLATAAVSHDIPS
>C3L33_13378-RA
MGLEISCQIELWKPVIAFLTAEASGGIVSLFRLTDKSPLGTTGKFKGVELTHRNFISSLAGFQAVRTVRSSPAVTLCAVPYFHVYGFVYSVRSVAMGENLVSIGKFDLVQMIKAIEGFRVTHVAVAPPVIVSMVNAYGLTESTAGISRMVGPNESQKFGASGRLVPYCQAKIVDVETGMDLPPFKQGELWXRGPSIMKGNFVIHSHVSSFNFQIFNVXYVGDPEATSAILDSEGWLRTGDLCYFDSEGFLYVVDRLKELIKYKGYQVT
>C3L33_13347-RA
MATLLQNQAQDQDHIFRSPYASIPVPDDVTLPEFVLQGFELYADRVAFVENESGKEYTHGEVVRETKRFAKALRSLGLRNGRVVVVLLPNVAEYAIVALGIMAAGGVFSGANPSGHASEIKKQVEAADARLIVTNGPNYEKVKGLGVPIIVLGEQRVESAIYWEELLEAADRASNGTITEPIAQTDLCALPFSSGTTGTSKGVMITHRNLISNLCSTLFSVRPELIGKVTTLGLMPFFHIYGLAGICCATLKNKGKVVVMGRYKIDTYLNALIDHEVTFAPIVPAIISDMVKILKNAAVDDFDLGKIKLHAVMTAAAPLAPEAYGMTEHSCITLTHGDPEKGHRIAKKNSVGFVLPNLEVKFIDPNTGRSLPKNTRGEICVRSQCVMKGYYKNKEETAQTIDENGWLHTGDIGYIDDDGDVFIVDRIKELIKYKGFQVAPAHLENIILTHPSVADAAVIPLPDEEAGEIPAACVVMDSNAKESEEDIMKYVASNVASYERVRVVQFVGAIPRSASGKILRRVLKEEMVKNMIIKTNPKLVRHC
>C3L33_13377-RA
MTLSILYLALFSLSVFISPSNPNAPESCQIELWKPVIAFVTAEASGGVVLLFWRTVLLDSLEFDSMMTTRSEEFFRFNIGTTGKFKGVELTHRNFISSLXGGQAVQTMRPSPAVTLCAVPYFHVYGFLYSMRTVAMGESLVSIGKFDLVQMIKAIEGFRVTHVAVAPPVIVSMVNVCDWTNGHDLSSLEVVVSAGAPLTKALIERFKKRFPRVQLPQAYGLTESTAVISRMVGPNESQKFGASGRLVPYCQAKIVDASGGIVSLFWRTVLLDSLEFDSMMTTRSKEFFRFNIG
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University