Enzyme
Requires Mg2+ for activity. The enzyme catalyses the methylation of daidzein and genistein. It does not methylate naringenin, apigenin, luteolin or kaempferol.
HI4'OMT
Enzyme
Isoflavone 4'-O-methyltransferase
Enzyme name
EC:2.1.1.46
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:4'-hydroxyisoflavone 4'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + a 4'-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 4'-methoxyisoflavone [RN:R07331]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];4'-methoxyisoflavone [CPD:C03074]
Product
Species information
Rhodamnia argentea
Species name
Silver malletwood (Rhodamnia argentea) is a species of eudicot in the family Myrtaceae (myrtle family).
Species info
Gene sequence info
Rhodamnia_argentea.HI4_OMT.fa
Download
>rna-XM_030688158.1
MSLGNGEGDATASELLRSQAHIWNHTYSFINSMCLKFAIELDIPDLIHRHGQPMTLLELVSMLHIQPTKAHCIHRLMRILVHSGFFELRDLDEAGGQTGYALTCASRLLVKHNPLSVAPYALFALEPISMDLWQNLSAWLRDGEGVHPSTFEMAHGVAAWEFGRRNPEANSLFDEAMASDSCLIAKVVVDTCGGVFEGLSSVVDVGGGTGTMGKAITEAFPHLECMVFDQPHVVEGSVGSERLKFVGGDMFVEIPPADAIFLKWILHDWSDEKCMAILKRCKEAVLGRGKIGKVIMIDIVVGNQTEDHRSTETQLFFDLVMMLAINGKERDEKEWEKLFVDAGFSGYKIVSRLGLRSLIEIYP
>rna-XM_030688147.1
MSAWLRDGEGVHPSTFEMAHGVTAWEFARRNPEANGLFNEAMACDSSLMAKVVVDTCGGVFEGLSSVVDVGGGTGTMAKAITEAFPHLECTVFDQPHVVEGLVGSGSLKFVGGDMFVEIPPADAIFIKWVLHDWSDEKCIDILKRSKEAATGRGKAGKVIVIDMVVGNHTEDHTSTETQLFFDLYVMVTLNGKERDEKEWEKLFVDAGFSGYKIVSRLGLRSLIEIYP
>rna-XM_030696504.1
MDRLSSFGATKEILQAQSHLYNLTSIFVSSMSLKCAVQLCIPDAINDHKRPITLPELASALRIHPSKTTCLLRLMRVLVHLHIFAETLVPKHGGGEGEEVKAYVLTPSSSLLLSDKATGLSPYIVAMLDPALMAPWHFLGDWFRGNHENNCSNKLTSPFEAAHGLTLWDYGRKNSEFGDAFSGAMAIDSQMMDVVMKDCKHIFQGFDTLVDVGGGTGTVAKIISEACRGLKCTVLDLPHVVAGLPESENVKFVGGDMFEFIPPSDAILLKSILHNWSDADCVKVLQKCRKAIAGKNNEGGKVIIIDMVIGDDKDDDAEATATKLFFDMLMMTVVTGRERTEKEWEELFLEAGFRQHKITPMFGLRSLIEVFP
>rna-XM_030662333.1
MDRLSSFGATKEILQAQSHLYNLTSIFVSSMSLKCAVQLCIPDAINDHKRPITLLELALALRIHPSKTTCLHRLMRVLVHLHKFTETLVPKHGGGREEVKASVLTPSSSLLLSDKATGLSPFIVAMLDPALVTPWHFLGDWFPGNHENSCSNKLISPFEAAHGLTLWDYGRKNPEFSDALSGAMAIDSQMMNVVMKDCKHIFQGLDTLVDVGGGTGTVLDLPHVVAGLPESENVKFVGADVFEFIPPWDAILLK
MSLGNGEGDATASELLRSQAHIWNHTYSFINSMCLKFAIELDIPDLIHRHGQPMTLLELVSMLHIQPTKAHCIHRLMRILVHSGFFELRDLDEAGGQTGYALTCASRLLVKHNPLSVAPYALFALEPISMDLWQNLSAWLRDGEGVHPSTFEMAHGVAAWEFGRRNPEANSLFDEAMASDSCLIAKVVVDTCGGVFEGLSSVVDVGGGTGTMGKAITEAFPHLECMVFDQPHVVEGSVGSERLKFVGGDMFVEIPPADAIFLKWILHDWSDEKCMAILKRCKEAVLGRGKIGKVIMIDIVVGNQTEDHRSTETQLFFDLVMMLAINGKERDEKEWEKLFVDAGFSGYKIVSRLGLRSLIEIYP
>rna-XM_030688147.1
MSAWLRDGEGVHPSTFEMAHGVTAWEFARRNPEANGLFNEAMACDSSLMAKVVVDTCGGVFEGLSSVVDVGGGTGTMAKAITEAFPHLECTVFDQPHVVEGLVGSGSLKFVGGDMFVEIPPADAIFIKWVLHDWSDEKCIDILKRSKEAATGRGKAGKVIVIDMVVGNHTEDHTSTETQLFFDLYVMVTLNGKERDEKEWEKLFVDAGFSGYKIVSRLGLRSLIEIYP
>rna-XM_030696504.1
MDRLSSFGATKEILQAQSHLYNLTSIFVSSMSLKCAVQLCIPDAINDHKRPITLPELASALRIHPSKTTCLLRLMRVLVHLHIFAETLVPKHGGGEGEEVKAYVLTPSSSLLLSDKATGLSPYIVAMLDPALMAPWHFLGDWFRGNHENNCSNKLTSPFEAAHGLTLWDYGRKNSEFGDAFSGAMAIDSQMMDVVMKDCKHIFQGFDTLVDVGGGTGTVAKIISEACRGLKCTVLDLPHVVAGLPESENVKFVGGDMFEFIPPSDAILLKSILHNWSDADCVKVLQKCRKAIAGKNNEGGKVIIIDMVIGDDKDDDAEATATKLFFDMLMMTVVTGRERTEKEWEELFLEAGFRQHKITPMFGLRSLIEVFP
>rna-XM_030662333.1
MDRLSSFGATKEILQAQSHLYNLTSIFVSSMSLKCAVQLCIPDAINDHKRPITLLELALALRIHPSKTTCLHRLMRVLVHLHKFTETLVPKHGGGREEVKASVLTPSSSLLLSDKATGLSPFIVAMLDPALVTPWHFLGDWFPGNHENSCSNKLISPFEAAHGLTLWDYGRKNPEFSDALSGAMAIDSQMMNVVMKDCKHIFQGLDTLVDVGGGTGTVLDLPHVVAGLPESENVKFVGADVFEFIPPWDAILLK
Sheng jun & Dong yang Teams, Yunnan agriculture University