Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Rhizophora apiculata
Species name
Rhizophora apiculata is a species of eudicot in the family Rhizophoraceae (red mangrove family).
Species info
Gene sequence info
Rhizophora_apiculata.COMT.fa
Download
>evm.model.scaffold_490.76
MSPYVEEIVKPGNEDDADCMFAMQLTVSSFVSVALRTVIELGLFEIIAKAGKGAQLSASEIASHLPTKTSDTPAIIDRMLRLMASYSILTCSLVNDKEGYPQRLYGLGPVCKYLTRDEDGVSFAPVFQSYSKFAIDSCYHLKDAILEGGTPILRAHGKHVFEDANDEFRSLFNEAMYNNTVIIMKKVIEIYKGFEDLREVVDVGGGLGANLKIIVSKYPHIKGINFDLPHVIKDAPAIPGVEHVGGDMFLSIPKAEAIFMKSILHDWGDEQCVKILKNCYDALPEIGKVIAVESVLPELPDTNFVSKHSCNFDVAMFVANPGGKERTEKELQALAKEAGFSAMELICRAYSSWVIVFYKRV
>evm.model.scaffold_490.77
MSPYVEEVVKPANEDDADCMFAMQLTVSTLFDVALRTVIELGLFEIIAKAGKDAQLSASEIASHLPTKTSDTPAIIDRMLRLMASYSVLTCSLVNDKEGYPQRLYGLGPVCKYFTRDEDGVSFAPVFQSYSKFAIDSCYHLKDAILEGSTPILRAHGKHVFEDANDEFRSLFNEAMYNNTVIIMKKVIEIYKGFEDLREVVDVGGGLGANLKIIVSKYPHIKGINFDLPHVIKDAPAFPGVEHVGGDMFLSIPKAEAIFMKSVLHDWGDEQCVKILKNCYDALPEIGKVIAVESVLPELPETNFASKHGYIYDVAMFVANPGGKERTEKELQALAKESGFSAMELICRAYGSWVIAFYKRV
>evm.model.scaffold_490.115
MSQYVEKVVKPADVDDADCMFAMQLTVSSFFNVTLRTVIELGLLEIIAKAGKGAQLSASEIASHLPTKTPDTPAIIDRMLRLMASYSILTCSLVNDKEGHPQRLYGLGPVCKYLTRDEDGVSFAPVFQSHSSFAIDSCYHVKDAVLEGGIPIVRAHGKHVFENVEDEFRRLFNEAMYNYTVIIMKRVIEIFEGFEDLRELVDVGGGLGANLKIIVSKYPHIKGINFDLPHVIKDAPAIPGVEHVGGDMFLSVPKAEAFFMKSILHDWGDEQCVKILKNCYDALPEIGKVIAVESVLPELPETNFVSKHACNIDVAMFLATYGGKERTDKELEALGKKAGFSAMELVCRAYSSWVIVFYKRV
>evm.model.scaffold_490.125
MWCRYYMKDAVLEGGIPFNKAHGMTSFDYHGKDLRFNKVFNKGMSDHSTVTMKKILETYHGFEGLTSVVDVGGGTGAVLGMIVSKYTTLKGINFDLPHVIKDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKFLKNCYDALPANGKVIVAEYILPEAPDASLATKCVIHVDLIMLAHNPGGKERTLKEFEALAKKAGFQGFRVVCSAFSTQGVRERSLTTYLHRSSAAAVCSSSPLFAINRHQNRSLGKFQLNLSNSPSSISSSFFPTTPVRHLRTGRDSSFSYEIAPPVNWGIRIVPEKKAYVIERFGKYVKTLPSGIHFLIPIVDRIAYVHSLKEEAIPIPDQSAITKDNVSILIDGVLYVKIVDPKLASYGVENPIYAVIQLAQTTMRSELGKITLDKTFEERDTLNEKIVEAINVAAKDWGLQCLRYEIRDISPPRGVRAAMEMQAEAERKKRAQVLESEGERQANINIADGKKNAVILASEAAKMDQVNRAQGEAEAILAKAQATAKGLVMVSQALKDTGGMEAASMKIAELYIHAFGNIAKEGTTMLLPSDNANPANMMAQALTMYKSLVGNVSNRGGHEFLKEGMKDIADSGETIGENTEARAVDTSHHDEPQFSLQRPKKGE
>evm.model.scaffold_500.581
MGIVIGCNKIKGVEVLDGMCEDQMRIEKRDIEEANNNGGDEKIIARNFWDVESPRCNNASDEFRASEENNGLNENLVEGLCELNGLQDEIEQRIPDKESGGIGREDNKRNPSSQEVDMEAVLCVPHVGGKENMLQDNVESDQNLEVEDDLLSKKSISDVSKGLRKKKKKHDGSSYDSAVASQKGMDTSTLYGQVLPLEKELFFLCWNFLSDAVYAGIGHFEQILYSLDTASNLVQGLDMQLSFWEPLFLLGLLCYPYPDGPVGIAMFCYQGPMNRRVCTQNHEVVVGSLACHEVLGCSGDAAGLEGSYSLNPVCEDFVQDQDGRSVGPLLAMVQDKVFFECCSNLLRLQKDGEEKHKSQVQPSLLYFLGEEEMGNLREWNFRVYK
>evm.model.scaffold_822.68
MSPSLYEQVKPSSDNEEDQDCLFAMQLSYGTFLPMALRAAIELDLFEIIAKAGKDARLSSSEIASHLATKNPDAPFVIDQMLCLLASYSILTCTLVTGQDDQPQRLYGLAPVCKYFTKNEDGVSFGPFLLASSSKYAMDTWYHLKDAILEGGNAVYMAHGKQIFEFQDEEFNNIFNQAMYSNTMIIMKKVLQTYKGLQDIKVLVDVGGGIGANLGLIVSKFPQIKGINYDLPHVIKQAPSYPGVVHVEGDMFNSVPKGEVIFMKSVLHDWDDDRCLKILKNCYDALPESGRVIAVESIVSEFPDTNLVSKNIFKSDLGMFIANGGRERTEKELEDLGKGAGFAAMKLVCRAYTSWVIEFYKGKN
>evm.model.scaffold_1266.198
MSESQNQYEEEETGKLAVLLANAGVLPMVLKSVVELNIIDILSAATSGGAWLSPSEIAARIPTKNPDAASLVDRMLRFLASFDVIKCSASIGEDGEVERAYGAAPICKFLTRNQVDGGGSIAPLLLLHHDEVFHKSWYHLNEVILEGGIPFNRAYGMTAFEYPATDQRFNGVFNQAMSNHTTLIIKKILEVYKGFDGLNVLVDVGGGVGVTLKMIVSSHPHIKGINYDLAHVLAAAPSYPGVEHVGGDMFVSVPKGDAIFMKWILHDWSDEHCLKLLNNCWEALPSNGKVIIVESILPQAPEKDVSSRIVFGQDLFMLAQNPGGKERSQKEFDALAKKSGFSGCAVVCSAYNSWVMEFRKRG
>evm.model.scaffold_1266.9
MASTFTTAMSSVGTLAALNGCVTDKKPAYPTFININNKLSSLASISGSSFARRHNVVLRRSRSPKICAMAKELHFNKDGSSIKKLQTGVNKLADLVGVTLGPKGRNVVLESKYGSPKIVNDGVTVAKEVELEDPVENIGAKLVRQAAAKTNDLAGDGTTTSVVLAQGLIAEGVKVVAAGANPVLITRGIEKTTKALVTDLRLMSKEVEDSELADVAAVSAGNNYEVGNMIAEALSKVGRKGVVTLEEGKSAENNLYVVEGMQFDRGYISPYFVTDSEKMAVEYENCKLLLVDKKITNARDLINVLEDAIKSGYPILIIAEDIEQEALATLVVNKLRGALKIAALKAPGFGERKSQYLDDIAVLTGGTVIRDEVGLSLDKVGKEVLGHTSKVVLTKDTTTIVGDGSTQEAVNKRVAQIRNLIEAAEQDYEKEKLNERIAKLSGGVAVIQVGAQTETELKEKKLRVEDALNATKAAVEEGIVVGGGCTLLRLASKVDAIKDGLDNDEEKVGADIVKRALSYPLKLIAKNAGVNGSVVSEKVLSSDNPRFGYNAATGNYEDLMAAGIIDPTKVVRCCLEHASSVAKTFLMSDCVVVEIKEPEPVPAGNPMDNSGYGRLLSSISSTSSPLPTGGGARLSPSEIAARIPTKNPDAASLVDRMLRFLASFDVNKCSASIGEDGEVERAYGAAPICKFFTRNQVDGGGSIAPLLLLRHDEVFHKSWYPLNDVILEGGIPFNRAYGMTAFEYPATDQRFNRVFNQAMSNHTTLIIKKILEVYKGFDGLNGLVDVGGGVGVTLKMIVSRHPHIKGINYDLPHVLAGAPSYPGVEHVGGDMFVSVPKGDAIFLKWILHDWSDEHCLKLLNNCWEALPSNGKVIIGESTLPQAPEKDVSSRIVFGQDLFMLAQTPGGKERSQKEFDALAKKSGFSGCEVVCSAYYSWVMEFHKRREANHL
>evm.model.scaffold_1266.12
MLLKSAPELTIINILSTATSGGALLSPSQIAARIPTKNPDLASLIERMLRFLASFDVIKCSVSTGENGEVEKAYGAAPIRKIKKMKRVYCSSVSVAP
>evm.model.scaffold_1266.11
MEHLKARAGWFQLCDFLDALDEWGRIWVGPGKSEWMLPDWSDEHCLKLLNNSWEALPSNGKVIIVESILPQAQEKDVSSQIVFGQDLFMLAQNLGGKERSQKEFHASAKTSGFSGCEVMRSAYNSWVMKFRQRG
>evm.model.scaffold_1266.13
MSQIQSQHDEVETAKQAILLANAGALIKVLKSAIELNIIDILYTATSSGAWLSPSDIAARIPTKNPDAASYMDRLLSFLASFDVVECSTSTNENGEVERAYGAAPICKFLTRNHDDGKGSLAPLFLFHHDEVLDKSWHCLNEAILEGGIPFNRAYGMTEFEYSATDQRFNRIFNEGMSNHSALIMKKVLEVYKGFDGLNVLVDVGGGIGVNLKMIVSRYPHIKGINYDLPHVVANAPSHPGIENVGGNMFVSVPKGDAIFLKWILEDWSDEHCLKILKNCWEALPSNGKVIIVELILPEKPEKDVSSRIVFGQDVILLAQNVGGRQRTQKEYDAMARKSGFSGCEAVCSAYNCLVLECHKGA
>evm.model.scaffold_1950.173
MEDENTESRNKARLGIMELTNLISVPMSLQAIVRLNVAEAIWQGGANPPLSASEILSCVHPSGGDPDNLERILRMLASYGVFDEHLSSNGSERKYSLTDIGKTLVTDGDGLSYAPYVLQHHQEALMKAWGLVHEAVLDPTTDPFVKANGEAAYIYYGKQPEMNGLMQKAMAGVSVPFMKALLEGYDGFQGVERLVDVGGSAGDCLRMIIKKYPGIREGINFDLPDVVAKAPHISRVSHVGGDMFKSIPEGDAIFMKWMLCTWPEDEGKKIMENCYKVLPAGGKLIACEPVVPENSDDSHRTRALLENDIFSMTIYGGKGKVRTEQEFKRLGLAVGFSQFRALCIDYFFTVLEFQK
MSPYVEEIVKPGNEDDADCMFAMQLTVSSFVSVALRTVIELGLFEIIAKAGKGAQLSASEIASHLPTKTSDTPAIIDRMLRLMASYSILTCSLVNDKEGYPQRLYGLGPVCKYLTRDEDGVSFAPVFQSYSKFAIDSCYHLKDAILEGGTPILRAHGKHVFEDANDEFRSLFNEAMYNNTVIIMKKVIEIYKGFEDLREVVDVGGGLGANLKIIVSKYPHIKGINFDLPHVIKDAPAIPGVEHVGGDMFLSIPKAEAIFMKSILHDWGDEQCVKILKNCYDALPEIGKVIAVESVLPELPDTNFVSKHSCNFDVAMFVANPGGKERTEKELQALAKEAGFSAMELICRAYSSWVIVFYKRV
>evm.model.scaffold_490.77
MSPYVEEVVKPANEDDADCMFAMQLTVSTLFDVALRTVIELGLFEIIAKAGKDAQLSASEIASHLPTKTSDTPAIIDRMLRLMASYSVLTCSLVNDKEGYPQRLYGLGPVCKYFTRDEDGVSFAPVFQSYSKFAIDSCYHLKDAILEGSTPILRAHGKHVFEDANDEFRSLFNEAMYNNTVIIMKKVIEIYKGFEDLREVVDVGGGLGANLKIIVSKYPHIKGINFDLPHVIKDAPAFPGVEHVGGDMFLSIPKAEAIFMKSVLHDWGDEQCVKILKNCYDALPEIGKVIAVESVLPELPETNFASKHGYIYDVAMFVANPGGKERTEKELQALAKESGFSAMELICRAYGSWVIAFYKRV
>evm.model.scaffold_490.115
MSQYVEKVVKPADVDDADCMFAMQLTVSSFFNVTLRTVIELGLLEIIAKAGKGAQLSASEIASHLPTKTPDTPAIIDRMLRLMASYSILTCSLVNDKEGHPQRLYGLGPVCKYLTRDEDGVSFAPVFQSHSSFAIDSCYHVKDAVLEGGIPIVRAHGKHVFENVEDEFRRLFNEAMYNYTVIIMKRVIEIFEGFEDLRELVDVGGGLGANLKIIVSKYPHIKGINFDLPHVIKDAPAIPGVEHVGGDMFLSVPKAEAFFMKSILHDWGDEQCVKILKNCYDALPEIGKVIAVESVLPELPETNFVSKHACNIDVAMFLATYGGKERTDKELEALGKKAGFSAMELVCRAYSSWVIVFYKRV
>evm.model.scaffold_490.125
MWCRYYMKDAVLEGGIPFNKAHGMTSFDYHGKDLRFNKVFNKGMSDHSTVTMKKILETYHGFEGLTSVVDVGGGTGAVLGMIVSKYTTLKGINFDLPHVIKDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCLKFLKNCYDALPANGKVIVAEYILPEAPDASLATKCVIHVDLIMLAHNPGGKERTLKEFEALAKKAGFQGFRVVCSAFSTQGVRERSLTTYLHRSSAAAVCSSSPLFAINRHQNRSLGKFQLNLSNSPSSISSSFFPTTPVRHLRTGRDSSFSYEIAPPVNWGIRIVPEKKAYVIERFGKYVKTLPSGIHFLIPIVDRIAYVHSLKEEAIPIPDQSAITKDNVSILIDGVLYVKIVDPKLASYGVENPIYAVIQLAQTTMRSELGKITLDKTFEERDTLNEKIVEAINVAAKDWGLQCLRYEIRDISPPRGVRAAMEMQAEAERKKRAQVLESEGERQANINIADGKKNAVILASEAAKMDQVNRAQGEAEAILAKAQATAKGLVMVSQALKDTGGMEAASMKIAELYIHAFGNIAKEGTTMLLPSDNANPANMMAQALTMYKSLVGNVSNRGGHEFLKEGMKDIADSGETIGENTEARAVDTSHHDEPQFSLQRPKKGE
>evm.model.scaffold_500.581
MGIVIGCNKIKGVEVLDGMCEDQMRIEKRDIEEANNNGGDEKIIARNFWDVESPRCNNASDEFRASEENNGLNENLVEGLCELNGLQDEIEQRIPDKESGGIGREDNKRNPSSQEVDMEAVLCVPHVGGKENMLQDNVESDQNLEVEDDLLSKKSISDVSKGLRKKKKKHDGSSYDSAVASQKGMDTSTLYGQVLPLEKELFFLCWNFLSDAVYAGIGHFEQILYSLDTASNLVQGLDMQLSFWEPLFLLGLLCYPYPDGPVGIAMFCYQGPMNRRVCTQNHEVVVGSLACHEVLGCSGDAAGLEGSYSLNPVCEDFVQDQDGRSVGPLLAMVQDKVFFECCSNLLRLQKDGEEKHKSQVQPSLLYFLGEEEMGNLREWNFRVYK
>evm.model.scaffold_822.68
MSPSLYEQVKPSSDNEEDQDCLFAMQLSYGTFLPMALRAAIELDLFEIIAKAGKDARLSSSEIASHLATKNPDAPFVIDQMLCLLASYSILTCTLVTGQDDQPQRLYGLAPVCKYFTKNEDGVSFGPFLLASSSKYAMDTWYHLKDAILEGGNAVYMAHGKQIFEFQDEEFNNIFNQAMYSNTMIIMKKVLQTYKGLQDIKVLVDVGGGIGANLGLIVSKFPQIKGINYDLPHVIKQAPSYPGVVHVEGDMFNSVPKGEVIFMKSVLHDWDDDRCLKILKNCYDALPESGRVIAVESIVSEFPDTNLVSKNIFKSDLGMFIANGGRERTEKELEDLGKGAGFAAMKLVCRAYTSWVIEFYKGKN
>evm.model.scaffold_1266.198
MSESQNQYEEEETGKLAVLLANAGVLPMVLKSVVELNIIDILSAATSGGAWLSPSEIAARIPTKNPDAASLVDRMLRFLASFDVIKCSASIGEDGEVERAYGAAPICKFLTRNQVDGGGSIAPLLLLHHDEVFHKSWYHLNEVILEGGIPFNRAYGMTAFEYPATDQRFNGVFNQAMSNHTTLIIKKILEVYKGFDGLNVLVDVGGGVGVTLKMIVSSHPHIKGINYDLAHVLAAAPSYPGVEHVGGDMFVSVPKGDAIFMKWILHDWSDEHCLKLLNNCWEALPSNGKVIIVESILPQAPEKDVSSRIVFGQDLFMLAQNPGGKERSQKEFDALAKKSGFSGCAVVCSAYNSWVMEFRKRG
>evm.model.scaffold_1266.9
MASTFTTAMSSVGTLAALNGCVTDKKPAYPTFININNKLSSLASISGSSFARRHNVVLRRSRSPKICAMAKELHFNKDGSSIKKLQTGVNKLADLVGVTLGPKGRNVVLESKYGSPKIVNDGVTVAKEVELEDPVENIGAKLVRQAAAKTNDLAGDGTTTSVVLAQGLIAEGVKVVAAGANPVLITRGIEKTTKALVTDLRLMSKEVEDSELADVAAVSAGNNYEVGNMIAEALSKVGRKGVVTLEEGKSAENNLYVVEGMQFDRGYISPYFVTDSEKMAVEYENCKLLLVDKKITNARDLINVLEDAIKSGYPILIIAEDIEQEALATLVVNKLRGALKIAALKAPGFGERKSQYLDDIAVLTGGTVIRDEVGLSLDKVGKEVLGHTSKVVLTKDTTTIVGDGSTQEAVNKRVAQIRNLIEAAEQDYEKEKLNERIAKLSGGVAVIQVGAQTETELKEKKLRVEDALNATKAAVEEGIVVGGGCTLLRLASKVDAIKDGLDNDEEKVGADIVKRALSYPLKLIAKNAGVNGSVVSEKVLSSDNPRFGYNAATGNYEDLMAAGIIDPTKVVRCCLEHASSVAKTFLMSDCVVVEIKEPEPVPAGNPMDNSGYGRLLSSISSTSSPLPTGGGARLSPSEIAARIPTKNPDAASLVDRMLRFLASFDVNKCSASIGEDGEVERAYGAAPICKFFTRNQVDGGGSIAPLLLLRHDEVFHKSWYPLNDVILEGGIPFNRAYGMTAFEYPATDQRFNRVFNQAMSNHTTLIIKKILEVYKGFDGLNGLVDVGGGVGVTLKMIVSRHPHIKGINYDLPHVLAGAPSYPGVEHVGGDMFVSVPKGDAIFLKWILHDWSDEHCLKLLNNCWEALPSNGKVIIGESTLPQAPEKDVSSRIVFGQDLFMLAQTPGGKERSQKEFDALAKKSGFSGCEVVCSAYYSWVMEFHKRREANHL
>evm.model.scaffold_1266.12
MLLKSAPELTIINILSTATSGGALLSPSQIAARIPTKNPDLASLIERMLRFLASFDVIKCSVSTGENGEVEKAYGAAPIRKIKKMKRVYCSSVSVAP
>evm.model.scaffold_1266.11
MEHLKARAGWFQLCDFLDALDEWGRIWVGPGKSEWMLPDWSDEHCLKLLNNSWEALPSNGKVIIVESILPQAQEKDVSSQIVFGQDLFMLAQNLGGKERSQKEFHASAKTSGFSGCEVMRSAYNSWVMKFRQRG
>evm.model.scaffold_1266.13
MSQIQSQHDEVETAKQAILLANAGALIKVLKSAIELNIIDILYTATSSGAWLSPSDIAARIPTKNPDAASYMDRLLSFLASFDVVECSTSTNENGEVERAYGAAPICKFLTRNHDDGKGSLAPLFLFHHDEVLDKSWHCLNEAILEGGIPFNRAYGMTEFEYSATDQRFNRIFNEGMSNHSALIMKKVLEVYKGFDGLNVLVDVGGGIGVNLKMIVSRYPHIKGINYDLPHVVANAPSHPGIENVGGNMFVSVPKGDAIFLKWILEDWSDEHCLKILKNCWEALPSNGKVIIVELILPEKPEKDVSSRIVFGQDVILLAQNVGGRQRTQKEYDAMARKSGFSGCEAVCSAYNCLVLECHKGA
>evm.model.scaffold_1950.173
MEDENTESRNKARLGIMELTNLISVPMSLQAIVRLNVAEAIWQGGANPPLSASEILSCVHPSGGDPDNLERILRMLASYGVFDEHLSSNGSERKYSLTDIGKTLVTDGDGLSYAPYVLQHHQEALMKAWGLVHEAVLDPTTDPFVKANGEAAYIYYGKQPEMNGLMQKAMAGVSVPFMKALLEGYDGFQGVERLVDVGGSAGDCLRMIIKKYPGIREGINFDLPDVVAKAPHISRVSHVGGDMFKSIPEGDAIFMKWMLCTWPEDEGKKIMENCYKVLPAGGKLIACEPVVPENSDDSHRTRALLENDIFSMTIYGGKGKVRTEQEFKRLGLAVGFSQFRALCIDYFFTVLEFQK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University