Enzyme

Requires Fe2+ and ascorbate. This plant enzyme catalyses an early step in the flavonoid biosynthesis pathway, leading to the production of flavanols and anthocyanins. Substrates include (2S)-naringenin, (2S)-eriodictyol, (2S)-dihydrotricetin and (2S)-pinocembrin. Some enzymes are bifuctional and also catalyse EC 1.14.20.6, flavonol synthase.

F3H

Enzyme

Flavanone 3-hydroxylase

Enzyme name

EC:1.14.11.9

Entry

Oxidoreductases;Acting on paired donors, with incorporation or reduction of molecular oxygen;With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

Class

(2S)-flavan-4-one,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)

Sysname

a (2S)-flavan-4-one + 2-oxoglutarate + O2 = a (2R,3R)-dihydroflavonol + succinate + CO2 [RN:R07329]

Reaction

(2R,3R)-dihydroflavonol [CPD:C21417];succinate [CPD:C00042];CO2 [CPD:C00011]

Product

Species information

Acer yangbiense

Species name

Acer yangbiense is a species of eudicot in the family Sapindaceae (soapberry family).Acer yangbiense is a newly described critically endangered endemic maple tree confined to Yangbi County in Yunnan Province in Southwest China. It was included in a programme for rescuing the most threatened species in China, focusing on plant species with extremely small populations (PSESP).

Species info

Gene sequence info

Acer_yangbiense.F3H.fa

Download
>Acyan06G0060000.1
MAPSTLTALAQEKTLNKSFVRDEDERPKVAYNQFSSEIPVISLAGIDEVDGRRAEICKKIVEACEDWGVFQVIDHGVDTKLISDMTRLAREFFALPPEDKLRFDMSGGKKGGFIVSSHLQGEAVQDWREIVTYFSYPTKTRDYSRWPDKPEGWIDATKEYSDKLMGLACKLLEVLSEAMGLEKEALTKACVDMDQKVVVNYYPKCPQPDLTLGLKRHTDPGTITLLLQDQVGGLQATRDNGKSWITVQPIDGAFVVNLGDHGHYLSNGRFKNADHQAVVNSNYSRLSIATFQNPAPEATVYPLKIREGEKSVLEEPITFAEMYRRKMSKDLELARLKKLAKEQQLQDLENPKLDAKPIEQIFA

Sheng jun & Dong yang Teams, Yunnan agriculture University