Enzyme
Requires Mg2+ for activity. The enzyme catalyses the methylation of daidzein and genistein. It does not methylate naringenin, apigenin, luteolin or kaempferol.
HI4'OMT
Enzyme
Isoflavone 4'-O-methyltransferase
Enzyme name
EC:2.1.1.46
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:4'-hydroxyisoflavone 4'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + a 4'-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 4'-methoxyisoflavone [RN:R07331]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];4'-methoxyisoflavone [CPD:C03074]
Product
Species information
Quercus suber
Species name
Cork oak (Quercus suber) is a species of eudicot in the family Fagaceae (beech family).
Species info
Gene sequence info
Quercus_suber.HI4_OMT.fa
Download
>rna-XM_024051258.1
MRWLCLIVTHNVEVEVEVFHQLHYSSLASSNLPQFSRVSSSVTKAARRSFCLIRLEYQLHCSLRTSTSGAKAAACKIMDLVHGQRASELFQAQSHLYKHIFNFIGSMSLKCALQLGIPDIIHNHGKPITLPELILALQIHPTKAGFVHRLMRLLVHCGFFVTTRVHINQEAEEEEAYDLTPSSRILLKDNVTNLSPFLLAMLDPVFVSPWHFLESWFRGDKVTPFESAHGMSLWDYADQKPDFNDSFNKAMTSDSGMMNLVVKDCKPVFEGLDALVDVGGGTGTCARIISEAFPHLKCTVLELPHVVANLPDNSNLNFVGGDMFQSIPSADAILLKLVLHALSDEECVKVLKKCREAISNKGKEGKVIIIDIVIDEKKDEHEITSAKLFFDMLMMVVVTGRERREKEWEKLFVEAGFSHYKIKPLFGLRSLIEVYP
>rna-XM_024054284.1
MDLILGVGVSELFQVHCHLYKHIFSYLDSMSLKCAIQLGIPDAIHNHGQPITLQELVSKLNIHPKKTSCVHRLMRLLVHSGFFAKTTVHENQEKEKEEEAYTLTPSSRLILKDNATSLSPFVLALLDPALVSPWQFLGDWFQGSELTPFEKAHGKCFWDYCNQSPEYNNIFNEGMASDSRLMSLVVKDYQPIFEGLGSLVDIGGGTGTVARIISEAFPHMKCTVFDLPHVVANLPDSKNLKFVGGDMFQYIPPADAMLFKSILHDWSDEECVNILKNCKEAIGKIGKEGKVIIIDVVINQEKDEHDVTSTTKLLLDALIMSLVTGKERNKREWEDLFLVAGFSHYKIVSSFGMMSVIEIYP
>rna-XM_024054858.1
MDLIHGEGVNELFQVQCHLYKQVFSYIDSMSLKCAIQLAIPDTIHNHGQPITLQELVSKLNIHPKKTSCVHRLMRLLVHSGFFAKTIVHENQEKEKEEEAYTLTPSSRLILKDNVTSLSPFVLAMLDPALVSPWQFLGDWFPGSELTPFEKAHGKGVLDYCNQNPEYNNIFNEGMASDSRLMNLVVKDYKPIFEGLGSLVDVGGGTGTVARIISEAFPHMKCTVLDLPHVVANLPDSKNLKFVGGDMFQYIPPADVILLKWILHDWSDEECVNILKNCKEAITSRGKEGKVIIIDVVVNQEKDKHDVTTTKLLFDALMMVVLTGQERNKKEWEKLFLEAGFSHYKIVSSFGMKSVIEIYL
>rna-XM_024020060.1
MDLIHGEGVSELFQAQCHLYKHIFSYIDSMSLKCAIQLGIPDTIHNHGQPITLQELVSKLHIHPKKTSCLHRLMRLLVHSGFFAKTIVHENQEKEKEEEAYTLTPSSRLILKDNATSLSPFVLAMLDPALVSPWQFLGDWFRGSELTPFEKAHGKGVWDYCNQNPEYNNIFNEGMASDSRLMNLVVKDYKPIFEGLGSLVDVGGGTGTVARIISEAFPHMKCTVFDLPHVVANLPDSKNLKFVAGDMFQYIPPADAVLFKWILHDWSDEECVNILKNCKEAITSKGKEGKVIIIDVVINQEKDEHDVTTTKLLFDALMMAYVTGKERNKKEWEKLFLEAGFSHYKIVSSFGMKSVIEIYP
>rna-XM_024020968.1
MDLIHGEGVSELFQVQCHLYKHIFSYIDSMSLKCAIQLGIPDTIHNHGQPITLQELVSKLHIHPKKTNCVHRLMRLLVHSGFFAKTIVHENQEKEKEKEAYTLTPSSRLILKDNVTSLSPFVLAMLDPALVSPWQFLGDWFQGSELTPFEKAHGKGMWDYCNQNPEYNNIFNEGMASDSRLMNLVVKDYKPIFEGLGSLVDVGGGTGTVARIISEAFPHMKCTVFDLPHVVANLPDSKNLKFVAGDMFQYIPPADAVLFKWILHDWSDEECVNILKNCKEAITSKGKEGKVIVIDVVINQEKDEHDVTTTKLLFDALMMVLLTGKERNKKEWEKLFLEAGFSYYKIVSSFGMKSVIEIYP
>rna-XM_024020971.1
MDLIHGEGVSELFQVQCHLYKHIFSYIDSMSLKCAIQLGIPDTIHNHGQPITLQELVSKLNIHPEKTSCVHRLMRLLVHSGFFAKTIVHENQEKEKEEEAYTLTPSSRLILKENVTSLSPFVLAMLDPALVSPWQFLGDWFQGSELTPFEKAHGKGLWDYCNQNPEYNNIFNEGMASDSRLMNLVVKDYKPIFEDLGSLVDVGGGTGTVARIISEAFPHMKCTVFDLPHVVANLPDSKNLKFVGGDMFQYIPPADAILFKWILHDWSDEECVNILKNCKEAITSQGKEGKVIVIDVVINQEKDEHDVTTTKLLFDALMMVLLTGKERNKKEWEKLFLEAGFSYYKIVSSFGMKSVIEIYP
>rna-XM_024020967.1
MDHIHGEGVSELFQVQCHLYKHIFSYIDSMSLKCAIQLGIPDAIHNHGQPITLQELVSKLNIHPKKTSCVHRLMRLLVHSGFFAKTTVHENQEKEKEEEAYTLTPSSRLILKDNATSLSPFVLASLDPALVSPWQFLGDWFQGSELTPFEKAHGKGFWDYCNQSPEYNNIFNEGMASDSRLMSLVVKDYQPIFEGLGSLVDIGGGTGTVARIISEAFPHMKCTVFDLPHVVANLPDSKNLKFVGGDMFQYIPPADAMLFKSILHDWSDEECVNILKNCKEAIGKKGKEGKVIIIDVVINQEKDEHDVTTTKLLLDAAIMSLVTGKERNKREWEELFLGAGFSHYKIVSSFGMKSVIEIYP
>rna-XM_024020966.1
MMDLIHGEGVSELFQGQCHLFKHIFSYIDSMSLKCAIQLGIPDIIHNHGQPITLPELVSKLHIHPKKTSCVHRLMRLLVQSGFFTKTIVHENQEKEKEEEAYTLTPSSRLILKDNVTSFSTYVLAMLDPVSLSPWQFLGDWFQGSELTPFEKTHGKGFWDHCNQSPEFNHYFNEAMASDSQLMNLVIKDYKPIFEGLGSLVDVGGGTGTMARIISETFPHMKCTVLDLPHVVANLPDGKNLKYVVGDMFQYIPPADAILFKWILHNWSDEECVNVLKNCKEAIMGKGKEGKVIIIDIMINEEKDEHDVTATKLLLDAVMMVLLTGKERNQKEWEKLFLEAGFSHYKIVSSFGMKSLIEVYP
>rna-XM_024032976.1
MEKTQREEKWNEEEQAEVDIWKYIFGFTEMAVVKCAIDLGIADAIESHGSPMTLYELSSTLGCAPSPLYRIMRFLMHRGIFKGKLARQGSPGYAQTPLSRRLMKHGEHSMAALILLESNPVMLTPWLSLSARVLADGTSSFEVAHGEDIWSYSASNPAHGQLINEAMACDARVIVPAMIHGCPEVFDGLSSLVDVGGGNGKTLKVLVKAFPWLRGINFDQPHVVSVAGVISGVENVGGDMFESVPKADAAFLKWVLHDWGDNECIQILKKCREAVLKNKGKVIIVDAVIEEAEKDKLTDVKLALDMAMMAHTNKGKERTLKEWGFVLGEAGFSRYTVKTIHAVQSVIEAFP
>rna-XM_024032972.1
MEKTQREAKWNEEEQAEVDIWKYILGFTEMAVVRCAIELGIADAIESHGSPMTLSELSSTLGCAPSPLYRIMRFLMHRGIFKGTLNSQGSPGYAQTPLSRRLMKHGEHSMAALILLESSPVLLTSWLSLSARVLDDDTSSFEVAHGEDIWSYSAANPAYGQLINEALACDARVLVPAMIHGCPEVFDGLCSLVDVGGGNGTTLKVLVKAFPWLRGINFDQPHVVSVAPVISGVENVGGDMFESVPKADAAFLKWILHDWGDNDCIQILKKCREAVLENKGKVIIVDAVIEEAEIDKLTDVRLALDMAMMTHTSKGKERSLKEWGFVLGEAGFSRYTLKTIHAVQSVIEAFP
>rna-XM_024032945.1
MEKTQREAKWNEEEQAEVDIWKYILGFTEMAVVRCAIELGIPDAIESHGSPMTLSELSSTLGCAPSPLYRTMRFLMHRGIFKGTLNSQGSPGYAQTPLSRRLMKHGEHSMAALILLESSPVLLTPWLSLSARVLEDDTSSFEVAHGEDIWSYSAANPAHGQLINEAMACDARVLVPAMIHGCPEVFDGLGSLVDVGGGNGTTLKLLVKAFPWLRGINFDQPHVVSVAGVISGVENVGGDMFESVPKADAAFLKWILHDWGDNECIQILKKCREAVLENKGKVIIVDAVIEEAEIDELTDVRLALDMAMMAHTNKGKERTLKEWGFVLGEAGFSRYTMKTIHAVQSVIEAFP
>rna-XM_024041097.1
MDLIHGEGVNELFQVQCHLYKHVFSYIDSMSLKCAIQLAIPDTIHNHGQPITLQELVSKLNIHPKKTSCVHRLMRLLVHSGFFAKTIVYENQEKEKEEEAYTLTPSSRLILKDNVTSLSPFVLAMLDPALVSPWQFLGDWFRGSELTPFEKAHGKGVLDYCNQNPEYNNIFNEGMASDSRLMNLVVKDYKPIFEGLGSLVDVGGGTGTVARIISEAFPHMKCTVLDLPHVVANLPDSKNLKFVGGDMFQYIPPADVILLKWILHDWSDEECVNILKNCKEAITSRGKEGKVIIIDVVVNQEKDKHDVTTTKLLFDALMMVVLTGQERNKKEWEKLFLEAGFSHYKIVSSFGMKSVIEIYL
MRWLCLIVTHNVEVEVEVFHQLHYSSLASSNLPQFSRVSSSVTKAARRSFCLIRLEYQLHCSLRTSTSGAKAAACKIMDLVHGQRASELFQAQSHLYKHIFNFIGSMSLKCALQLGIPDIIHNHGKPITLPELILALQIHPTKAGFVHRLMRLLVHCGFFVTTRVHINQEAEEEEAYDLTPSSRILLKDNVTNLSPFLLAMLDPVFVSPWHFLESWFRGDKVTPFESAHGMSLWDYADQKPDFNDSFNKAMTSDSGMMNLVVKDCKPVFEGLDALVDVGGGTGTCARIISEAFPHLKCTVLELPHVVANLPDNSNLNFVGGDMFQSIPSADAILLKLVLHALSDEECVKVLKKCREAISNKGKEGKVIIIDIVIDEKKDEHEITSAKLFFDMLMMVVVTGRERREKEWEKLFVEAGFSHYKIKPLFGLRSLIEVYP
>rna-XM_024054284.1
MDLILGVGVSELFQVHCHLYKHIFSYLDSMSLKCAIQLGIPDAIHNHGQPITLQELVSKLNIHPKKTSCVHRLMRLLVHSGFFAKTTVHENQEKEKEEEAYTLTPSSRLILKDNATSLSPFVLALLDPALVSPWQFLGDWFQGSELTPFEKAHGKCFWDYCNQSPEYNNIFNEGMASDSRLMSLVVKDYQPIFEGLGSLVDIGGGTGTVARIISEAFPHMKCTVFDLPHVVANLPDSKNLKFVGGDMFQYIPPADAMLFKSILHDWSDEECVNILKNCKEAIGKIGKEGKVIIIDVVINQEKDEHDVTSTTKLLLDALIMSLVTGKERNKREWEDLFLVAGFSHYKIVSSFGMMSVIEIYP
>rna-XM_024054858.1
MDLIHGEGVNELFQVQCHLYKQVFSYIDSMSLKCAIQLAIPDTIHNHGQPITLQELVSKLNIHPKKTSCVHRLMRLLVHSGFFAKTIVHENQEKEKEEEAYTLTPSSRLILKDNVTSLSPFVLAMLDPALVSPWQFLGDWFPGSELTPFEKAHGKGVLDYCNQNPEYNNIFNEGMASDSRLMNLVVKDYKPIFEGLGSLVDVGGGTGTVARIISEAFPHMKCTVLDLPHVVANLPDSKNLKFVGGDMFQYIPPADVILLKWILHDWSDEECVNILKNCKEAITSRGKEGKVIIIDVVVNQEKDKHDVTTTKLLFDALMMVVLTGQERNKKEWEKLFLEAGFSHYKIVSSFGMKSVIEIYL
>rna-XM_024020060.1
MDLIHGEGVSELFQAQCHLYKHIFSYIDSMSLKCAIQLGIPDTIHNHGQPITLQELVSKLHIHPKKTSCLHRLMRLLVHSGFFAKTIVHENQEKEKEEEAYTLTPSSRLILKDNATSLSPFVLAMLDPALVSPWQFLGDWFRGSELTPFEKAHGKGVWDYCNQNPEYNNIFNEGMASDSRLMNLVVKDYKPIFEGLGSLVDVGGGTGTVARIISEAFPHMKCTVFDLPHVVANLPDSKNLKFVAGDMFQYIPPADAVLFKWILHDWSDEECVNILKNCKEAITSKGKEGKVIIIDVVINQEKDEHDVTTTKLLFDALMMAYVTGKERNKKEWEKLFLEAGFSHYKIVSSFGMKSVIEIYP
>rna-XM_024020968.1
MDLIHGEGVSELFQVQCHLYKHIFSYIDSMSLKCAIQLGIPDTIHNHGQPITLQELVSKLHIHPKKTNCVHRLMRLLVHSGFFAKTIVHENQEKEKEKEAYTLTPSSRLILKDNVTSLSPFVLAMLDPALVSPWQFLGDWFQGSELTPFEKAHGKGMWDYCNQNPEYNNIFNEGMASDSRLMNLVVKDYKPIFEGLGSLVDVGGGTGTVARIISEAFPHMKCTVFDLPHVVANLPDSKNLKFVAGDMFQYIPPADAVLFKWILHDWSDEECVNILKNCKEAITSKGKEGKVIVIDVVINQEKDEHDVTTTKLLFDALMMVLLTGKERNKKEWEKLFLEAGFSYYKIVSSFGMKSVIEIYP
>rna-XM_024020971.1
MDLIHGEGVSELFQVQCHLYKHIFSYIDSMSLKCAIQLGIPDTIHNHGQPITLQELVSKLNIHPEKTSCVHRLMRLLVHSGFFAKTIVHENQEKEKEEEAYTLTPSSRLILKENVTSLSPFVLAMLDPALVSPWQFLGDWFQGSELTPFEKAHGKGLWDYCNQNPEYNNIFNEGMASDSRLMNLVVKDYKPIFEDLGSLVDVGGGTGTVARIISEAFPHMKCTVFDLPHVVANLPDSKNLKFVGGDMFQYIPPADAILFKWILHDWSDEECVNILKNCKEAITSQGKEGKVIVIDVVINQEKDEHDVTTTKLLFDALMMVLLTGKERNKKEWEKLFLEAGFSYYKIVSSFGMKSVIEIYP
>rna-XM_024020967.1
MDHIHGEGVSELFQVQCHLYKHIFSYIDSMSLKCAIQLGIPDAIHNHGQPITLQELVSKLNIHPKKTSCVHRLMRLLVHSGFFAKTTVHENQEKEKEEEAYTLTPSSRLILKDNATSLSPFVLASLDPALVSPWQFLGDWFQGSELTPFEKAHGKGFWDYCNQSPEYNNIFNEGMASDSRLMSLVVKDYQPIFEGLGSLVDIGGGTGTVARIISEAFPHMKCTVFDLPHVVANLPDSKNLKFVGGDMFQYIPPADAMLFKSILHDWSDEECVNILKNCKEAIGKKGKEGKVIIIDVVINQEKDEHDVTTTKLLLDAAIMSLVTGKERNKREWEELFLGAGFSHYKIVSSFGMKSVIEIYP
>rna-XM_024020966.1
MMDLIHGEGVSELFQGQCHLFKHIFSYIDSMSLKCAIQLGIPDIIHNHGQPITLPELVSKLHIHPKKTSCVHRLMRLLVQSGFFTKTIVHENQEKEKEEEAYTLTPSSRLILKDNVTSFSTYVLAMLDPVSLSPWQFLGDWFQGSELTPFEKTHGKGFWDHCNQSPEFNHYFNEAMASDSQLMNLVIKDYKPIFEGLGSLVDVGGGTGTMARIISETFPHMKCTVLDLPHVVANLPDGKNLKYVVGDMFQYIPPADAILFKWILHNWSDEECVNVLKNCKEAIMGKGKEGKVIIIDIMINEEKDEHDVTATKLLLDAVMMVLLTGKERNQKEWEKLFLEAGFSHYKIVSSFGMKSLIEVYP
>rna-XM_024032976.1
MEKTQREEKWNEEEQAEVDIWKYIFGFTEMAVVKCAIDLGIADAIESHGSPMTLYELSSTLGCAPSPLYRIMRFLMHRGIFKGKLARQGSPGYAQTPLSRRLMKHGEHSMAALILLESNPVMLTPWLSLSARVLADGTSSFEVAHGEDIWSYSASNPAHGQLINEAMACDARVIVPAMIHGCPEVFDGLSSLVDVGGGNGKTLKVLVKAFPWLRGINFDQPHVVSVAGVISGVENVGGDMFESVPKADAAFLKWVLHDWGDNECIQILKKCREAVLKNKGKVIIVDAVIEEAEKDKLTDVKLALDMAMMAHTNKGKERTLKEWGFVLGEAGFSRYTVKTIHAVQSVIEAFP
>rna-XM_024032972.1
MEKTQREAKWNEEEQAEVDIWKYILGFTEMAVVRCAIELGIADAIESHGSPMTLSELSSTLGCAPSPLYRIMRFLMHRGIFKGTLNSQGSPGYAQTPLSRRLMKHGEHSMAALILLESSPVLLTSWLSLSARVLDDDTSSFEVAHGEDIWSYSAANPAYGQLINEALACDARVLVPAMIHGCPEVFDGLCSLVDVGGGNGTTLKVLVKAFPWLRGINFDQPHVVSVAPVISGVENVGGDMFESVPKADAAFLKWILHDWGDNDCIQILKKCREAVLENKGKVIIVDAVIEEAEIDKLTDVRLALDMAMMTHTSKGKERSLKEWGFVLGEAGFSRYTLKTIHAVQSVIEAFP
>rna-XM_024032945.1
MEKTQREAKWNEEEQAEVDIWKYILGFTEMAVVRCAIELGIPDAIESHGSPMTLSELSSTLGCAPSPLYRTMRFLMHRGIFKGTLNSQGSPGYAQTPLSRRLMKHGEHSMAALILLESSPVLLTPWLSLSARVLEDDTSSFEVAHGEDIWSYSAANPAHGQLINEAMACDARVLVPAMIHGCPEVFDGLGSLVDVGGGNGTTLKLLVKAFPWLRGINFDQPHVVSVAGVISGVENVGGDMFESVPKADAAFLKWILHDWGDNECIQILKKCREAVLENKGKVIIVDAVIEEAEIDELTDVRLALDMAMMAHTNKGKERTLKEWGFVLGEAGFSRYTMKTIHAVQSVIEAFP
>rna-XM_024041097.1
MDLIHGEGVNELFQVQCHLYKHVFSYIDSMSLKCAIQLAIPDTIHNHGQPITLQELVSKLNIHPKKTSCVHRLMRLLVHSGFFAKTIVYENQEKEKEEEAYTLTPSSRLILKDNVTSLSPFVLAMLDPALVSPWQFLGDWFRGSELTPFEKAHGKGVLDYCNQNPEYNNIFNEGMASDSRLMNLVVKDYKPIFEGLGSLVDVGGGTGTVARIISEAFPHMKCTVLDLPHVVANLPDSKNLKFVGGDMFQYIPPADVILLKWILHDWSDEECVNILKNCKEAITSRGKEGKVIIIDVVVNQEKDKHDVTTTKLLFDALMMVVLTGQERNKKEWEKLFLEAGFSHYKIVSSFGMKSVIEIYL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University