Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Punica granatum
Species name
Pomegranate (Punica granatum) is a species of eudicot in the family Lythraceae (loosestrife family).
Species info
Gene sequence info
Punica_granatum.4CL.fa
Download
>rna-XM_031526422.1
MISVAPSPESPADTTPHCGNTTTPPSPSSSTNAAGSCSSGDGIIFRSKLPAIPIPNHLPLHAYCFQSLPDSADRPCLIVGSSGKSYTYAETHLICRKTAAGLSNLGISRGDVIMILLPNCPEFVFTFIGASMIGAVTTTANPFYTPSEILKQFKASAAKLIVTQSSFVDKLGHFSRLSLHEEEEEEGVGGHRHRHRQGGSAAAILGKDFTVITVDDPPESCLHFSVLSEANDQSPPDWEQEVVHYYSASCSCSRKLEFEFDPDDPVALPFSSGTTGLPKGVVLTHRSLITSVAQQVDGENPNLHLRGDDVVLCLLPLFHIYSLNSVLLCSLRAGAAVLLMHKFEIGALLELIQRHRVSVAAVVPPLVLALAKNPVVEGFDLSSLRLVLSGAAPLAKDLEDALRTRVPQAVLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPVTGSSLGYNQSGEICIRGQQIMKGYLNDPEATARTIDVEGWLHTGDIGYVDEDDEVFIVDRVKEIIKFKGFQVPPAELEALLLSHASIADAAVVPQKDEAAGEVPVAFVVCSKGMEVTEEAIKQFVAKQRAQWMHMHMQVVFYKRLYKVYFVHAIPKSPSGKILRKDLRAKLAAAAASSTPL
>rna-XM_031528451.1
MKPKSFNPASQTHHSLRPALNFPTDPHLSLTSFLFSHASAHHPHCLALADADSGESFTFAQLQTRVSTFSHVLLHQFRIAKNDVILILSPNSAHFAICFLSIVSIGAVITTSNPLYTSFELSKQVNDSKPKLVITCPELFNKVEQFGLPTILFGAPASTASNKPKVWNYFDLIRTEDPRLEFPPVAVTQDDVAALMYSSGTTGTSKGTILTHRNFISTSLMVTSDQDRYREPRNVFLCFLPLFHIMGLSTILYSQLRRGNTVVLLKQFELENVLRCVEKYRVTHLYVAPPVMVAFAKQLILVKKYELSSLRQIGSGAAPLGKDVMEECSKIFPQAKIFQGYGMTETCGIISIEDTVEEPPLSGSTGTLVPGVESKIISVETMKPLPPNQLGEIWLRGPNMMRGYLNNPEATKLTIDEQGWVHTGDLGYFNDEGQLFVVDRLKDLIKCYGFQVAPAELEALLLSHPEILDAVVIPFPDEKAGEVPIAYIVRSPSSSIAETDVQEFVSKQVAPHKRLRRVNFITSVPKTAAGKILRRELKEKARSMI
>rna-XM_031530258.1
METKQDTVSQEFIFRSKLPDIYIPNHLPLHSYCFENISEFQDRPCLIDGSTGRIYTYSEVELTSRRVASGLNKLGIEQGQVIMLLLHNSPEFVHAFLGASFCGAMSTTANPFCTPPEIAKQAAASKARLIITQAEFAPKVKDFAEENGVKVMCIDSAPEGCLHFSELTQADEAEMPSVKIDPNDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFRKEDVILCVLPLFHIYSLNSIMLCGLRVGAAILIMQKFEIVKLMELVQRYKVTIAPFVPPIVLAMSKYADMDKYDLSSIRTVMSGAAPMGKELEDSVRAKLPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVNPDTGASLPRNQPGEICIRGNQIMKGYLNDPEATERTIDKDGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPSISDAAVVPMKDEAAGEVPVAFVIRSNGSKITEDDIKQYISKQVVFYKRINRVFFTEAIPKAPSGKILRKDLRAKLASGVSA
>rna-XM_031531771.1
MEKSGYGRDGIFRSLRPPLVLPRDPNLSMVSFLFKNSASYPDKPALIDADSGETLTYSQFKATVVKVSHGLVHLGIKKNDVVLIFAPNSIQFPVCFLGITAVGAVATTSNPLYTAGELSKQAKDSNPKLVITVPELWDRVKDFNLPTVFLGNRDFSHIKSGSAILGFRDLINLSRASSDFPMLSVGQADTAALLYSSGTTGTSKGVVLTHGNFIAASLMINMDQELAGETNNVFLCVLPMFHVFGLAVISYTQLRAGHAIVSMGKFEFERVLMAVEKYRVTNLWIVPPIIIALAKQSLVKKYDLSSLSHIGSGAAPLGKDVMEDCAKNFPHAAVSQGYGMTETCGIVSVENHRVGTRHTGSAGTLVSGVEAQIISVDTLKPLPPNQLGEIRVRGPNMMRGYYNNPQATKLTIDSKGWVHTGDLGYFDEEGQLFVVDRIKELIKYKGFQIAPAELEGLLLSHPEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEEDVQNFIANQVAPFKRLRRVTFIQTVPKSASGKILRRELIEKVRSRM
>rna-XM_031529500.1
MGACVDFSTQVHEHIFRSRFPPVQVPDVSLPDFVLQGWEPHADRVAFVEPVSGKTYTYAEVVRDVRRFSKALSSIGLRKGRVVVVALPNVAEYGIVALGIMAAGGVFSGANPAMHALEIKKQVEAADAKLIVTDGPNYEKVRSFGLPVIVLGDGEPIQTAMNWAELLEAGEKAGPGASVEAPLFHQDDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFSVTPDMIGQVTTLGLIPFFHIYGTTGICCATLRNKGKVVVMNRYDLRTFLSALITQEVTFAPIVPPVILNLVKNPIVEEFDLSKLKLMAVMTAAAPLAPEILSAFEAKFPGVLVQEAYGLTEHSCITLTHVGPAHGTAKRNSVGRVLPNLEVKFIDPDTGLSLPMNTPGELCVRSQCVMQGYYNNKEETSRTIDKDGWLHTGDIGYIDDDGDVFVVDRIKELIKYKGFQVAPAELEAILLGHSSVEDAAVVPLPDEEAGEIPAACVVLIPGAEETEQDIMNFMASNVATYKKVRAVQFVESIPKSPSGKILRRLLRDKLLEKMKKP
MISVAPSPESPADTTPHCGNTTTPPSPSSSTNAAGSCSSGDGIIFRSKLPAIPIPNHLPLHAYCFQSLPDSADRPCLIVGSSGKSYTYAETHLICRKTAAGLSNLGISRGDVIMILLPNCPEFVFTFIGASMIGAVTTTANPFYTPSEILKQFKASAAKLIVTQSSFVDKLGHFSRLSLHEEEEEEGVGGHRHRHRQGGSAAAILGKDFTVITVDDPPESCLHFSVLSEANDQSPPDWEQEVVHYYSASCSCSRKLEFEFDPDDPVALPFSSGTTGLPKGVVLTHRSLITSVAQQVDGENPNLHLRGDDVVLCLLPLFHIYSLNSVLLCSLRAGAAVLLMHKFEIGALLELIQRHRVSVAAVVPPLVLALAKNPVVEGFDLSSLRLVLSGAAPLAKDLEDALRTRVPQAVLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPVTGSSLGYNQSGEICIRGQQIMKGYLNDPEATARTIDVEGWLHTGDIGYVDEDDEVFIVDRVKEIIKFKGFQVPPAELEALLLSHASIADAAVVPQKDEAAGEVPVAFVVCSKGMEVTEEAIKQFVAKQRAQWMHMHMQVVFYKRLYKVYFVHAIPKSPSGKILRKDLRAKLAAAAASSTPL
>rna-XM_031528451.1
MKPKSFNPASQTHHSLRPALNFPTDPHLSLTSFLFSHASAHHPHCLALADADSGESFTFAQLQTRVSTFSHVLLHQFRIAKNDVILILSPNSAHFAICFLSIVSIGAVITTSNPLYTSFELSKQVNDSKPKLVITCPELFNKVEQFGLPTILFGAPASTASNKPKVWNYFDLIRTEDPRLEFPPVAVTQDDVAALMYSSGTTGTSKGTILTHRNFISTSLMVTSDQDRYREPRNVFLCFLPLFHIMGLSTILYSQLRRGNTVVLLKQFELENVLRCVEKYRVTHLYVAPPVMVAFAKQLILVKKYELSSLRQIGSGAAPLGKDVMEECSKIFPQAKIFQGYGMTETCGIISIEDTVEEPPLSGSTGTLVPGVESKIISVETMKPLPPNQLGEIWLRGPNMMRGYLNNPEATKLTIDEQGWVHTGDLGYFNDEGQLFVVDRLKDLIKCYGFQVAPAELEALLLSHPEILDAVVIPFPDEKAGEVPIAYIVRSPSSSIAETDVQEFVSKQVAPHKRLRRVNFITSVPKTAAGKILRRELKEKARSMI
>rna-XM_031530258.1
METKQDTVSQEFIFRSKLPDIYIPNHLPLHSYCFENISEFQDRPCLIDGSTGRIYTYSEVELTSRRVASGLNKLGIEQGQVIMLLLHNSPEFVHAFLGASFCGAMSTTANPFCTPPEIAKQAAASKARLIITQAEFAPKVKDFAEENGVKVMCIDSAPEGCLHFSELTQADEAEMPSVKIDPNDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFRKEDVILCVLPLFHIYSLNSIMLCGLRVGAAILIMQKFEIVKLMELVQRYKVTIAPFVPPIVLAMSKYADMDKYDLSSIRTVMSGAAPMGKELEDSVRAKLPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVNPDTGASLPRNQPGEICIRGNQIMKGYLNDPEATERTIDKDGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPSISDAAVVPMKDEAAGEVPVAFVIRSNGSKITEDDIKQYISKQVVFYKRINRVFFTEAIPKAPSGKILRKDLRAKLASGVSA
>rna-XM_031531771.1
MEKSGYGRDGIFRSLRPPLVLPRDPNLSMVSFLFKNSASYPDKPALIDADSGETLTYSQFKATVVKVSHGLVHLGIKKNDVVLIFAPNSIQFPVCFLGITAVGAVATTSNPLYTAGELSKQAKDSNPKLVITVPELWDRVKDFNLPTVFLGNRDFSHIKSGSAILGFRDLINLSRASSDFPMLSVGQADTAALLYSSGTTGTSKGVVLTHGNFIAASLMINMDQELAGETNNVFLCVLPMFHVFGLAVISYTQLRAGHAIVSMGKFEFERVLMAVEKYRVTNLWIVPPIIIALAKQSLVKKYDLSSLSHIGSGAAPLGKDVMEDCAKNFPHAAVSQGYGMTETCGIVSVENHRVGTRHTGSAGTLVSGVEAQIISVDTLKPLPPNQLGEIRVRGPNMMRGYYNNPQATKLTIDSKGWVHTGDLGYFDEEGQLFVVDRIKELIKYKGFQIAPAELEGLLLSHPEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEEDVQNFIANQVAPFKRLRRVTFIQTVPKSASGKILRRELIEKVRSRM
>rna-XM_031529500.1
MGACVDFSTQVHEHIFRSRFPPVQVPDVSLPDFVLQGWEPHADRVAFVEPVSGKTYTYAEVVRDVRRFSKALSSIGLRKGRVVVVALPNVAEYGIVALGIMAAGGVFSGANPAMHALEIKKQVEAADAKLIVTDGPNYEKVRSFGLPVIVLGDGEPIQTAMNWAELLEAGEKAGPGASVEAPLFHQDDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFSVTPDMIGQVTTLGLIPFFHIYGTTGICCATLRNKGKVVVMNRYDLRTFLSALITQEVTFAPIVPPVILNLVKNPIVEEFDLSKLKLMAVMTAAAPLAPEILSAFEAKFPGVLVQEAYGLTEHSCITLTHVGPAHGTAKRNSVGRVLPNLEVKFIDPDTGLSLPMNTPGELCVRSQCVMQGYYNNKEETSRTIDKDGWLHTGDIGYIDDDGDVFVVDRIKELIKYKGFQVAPAELEAILLGHSSVEDAAVVPLPDEEAGEIPAACVVLIPGAEETEQDIMNFMASNVATYKKVRAVQFVESIPKSPSGKILRRLLRDKLLEKMKKP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University