Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Primula vulgaris
Species name
Primula vulgaris is a species of eudicot in the family Primulaceae (primrose family).
Species info
Gene sequence info
Primula_vulgaris.4CL.fa
Download
>mRNA29870
MLSVASLDTTTTSPAPKPAVVDINVTDLQISSNTNIIHDQLTSSSPHHEYQIPKEDHIFKSRLPDINIPNHLSLHTYVFENVPQHPHRTCLIVGSTGITYSFAQTHLISRKVASGLSRLGITKGDVIMVLLQNCAEFVFSFMGASMIGAVTTTANPFYTPAEVFKQFRTSGTKIIITESRYVDKLRNMGDDKYRPIMGQDFKVITINDAPENCLHYSVLSEADENEIDLDSIKIDPEDAVVLPFSSGTTGLPKGVILTHKSQTTSVSQQVDGENPNLHLKEEDVVLCVLPLFHIFSLNSVLLNSLRAGAPVLLMHKFEIFTLLELIQRHKVSVAAVVPPLVLALAKNPAVADYDLSSLRIVLSGAAPLGKELEEALHRRVPQAVFGQGYGMTEAGSVLTMCLSFAKQPTPTKSGSCGTVVRNAELKVVDPDTGRSLPRNQPGEICVRGFQIMKGYLNDPEATAVTIDVDGWLHSGDIGYVDDDDEVFIVDRVKELIKFKGFQVPPAELEALLVNHPSISDAAVVPQKDDAAGEVPVAFVVRSNGFELAEDDVKQFIAKQVVFYKKLHKVYFVTTIPKSPSGKILRKELRARLGTPSPVV
>mRNA8275
MEILNETKPVLSNPLCYSSETGIYSSKYLKMSLPTNPLTDVVSYIFSKKHTGNLALIDSFSGHSIPYSELLPRVKSVASGLRQLGISRGDVVLILLPNSIYFPVILLGVMSIGAVVSPMNPLSSLNEIKKQTLDCRAEVAFTTHTKSQIFDKLGLKTITVPENVDYGFLNNDNFFSSDPNLAPQVNIRQDDTAAIMYSSGTTGTCKGVMLSHKNFISVIELFVRFEASQYDYLASENVYLAVLPMFHIYGMSLFVMGLFTLGGTIVVMRKFEVGEMVKVIDTYKITHFHAVPPLINALTERAKRGEKERLKSLKQVTSGAAPLSRKSADEFVCTLPQVDFIQGYGMTESTAVATRGFNTKKLCNYTSIGLLSPNTEAKVVDIVTGSFMPPGKRGELLLRGPGTMKGYLNNPEATAQAIDKDGWLHTGDIVYFDSDGYIYICDRLKEMIKYKGFQIAPAELESLLISHPDVIDAAVTAAKDEKAGEVPIAFVVKRSGSRLSESALSDYVAKQVSPYKKLRKVVFTQSIPKSAAGKILRRELKTLIPARL
>mRNA24282
METKTRKEEMIFRSKLPDIYIPKHLPLHSYCFENISQVASRPCLINGATGEIHTYADVELTAKKVAAGLDKLGIKQGDTIMILLPNSPEFVFAFIGASYRGAISTMANPFFTAAEVVKQAKASKARLIVTQASYVDKVMEYADDNDIKVICIDTPPEGCLPFSALTDSSPEDVPSVTISPNDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYMNSDDVVMCVLPLFHIYSLNSVLLCSLRVGAAILIMQKFEINSFLGLIEKYKVTIGAFVPPIVLAIAKSPQVDKYDLSTIRLVQSGAAPLGKALEDTVRAKFPNARLGQGYGMTEAGPVLALCLAFAKEPYEIKSGACGSVMRNAEMKIIDPDTGDSLSRNQPGEICIRGDQIMKGYLNDPEATERTIDNEGWLHTGDIGYIDEDDELFIVDRLKELIKYKGFQVPPAELEALLLTHPQISDAAVVPMKDESAGEVPVAFVVKPNGVPITEDEIKQFVAKQVVFYKRICKVFFIDAIPKAPSGKILRKDLRARLAASLAN
>mRNA25922
MVINTQQKEMIFRSKLPDIYIPNHLPLHAYCFENISEFSSKPCLINGATGEIHTYADVEMTSKKVASGLDKHGIRQGDTIMILLPNSPEFVFAFLGASYRGAISTMANPFFTAAEVVKQMKASNAKLVVTQASYVDKLKEYANENDVKIICIDTPPEGCLHFSELINLSDEEPPSVTISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYMHSDDVALCVLPLFHIYSLNSVLLCGLRAGAAILIMQKFEINSFFGLIEKYKVTIGPFVPPIVLAIAKSPVVDDYDMSTIRMVMSGAAPLGKELEDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKKPYEIKSGACGTVVRNAEMKIIDPDTNASLPRNQPGEICIRGDQIMKGYLNDPVATSQTIDKEGWLHTGDIGYIDNDDELFIVDRLKELIKYKGFQVPPAELEALLLTHPKIGDAAVVPMKDESAGEVPVAFVVRSNGYQITEDEIKQFVSKQVVFYKRLSRVFFTDTIPKAPSGKILRKDLRARLAAGLAN
>mRNA15006
MAPILLNQSQDEENIFRSPYKSVEVPENMTLPEFILQNAELYTEKVAFVDISSGKEYTYGQVVRDVKRFANALRSLGLRKGRVVVVVLPNVAEYAIVSLGIMAAGGVFSGANPLAHHSEIKTQVEVADAKLVVTNGTNYDKVKDLGLPIIVLGEERVESAMYWDELLEAADRASTDTINEPIYQTDLCALPFSSGTTGKSKGVMLTHRNLVSNLCSTLFSVGPELVGLVVVLGLMPFFHIYGLVGICCATLRNKGKVVVMERYTLETFMNALILHEVSFAPIVPAVISDMAKNSLVDEFDLSKLNLRAVMTAAAPLAPEVLSGFERKFPGVEVQEAYGMTEHSCITLSHGDPHKGQRRAKKNSVGFVLPNIEVRFVDPNTGRSLPKNTQGEICVRSQCVMKGYYQNEDETAQTIDKDGWLHTGDIGYIDDDGDVFIVDRIKELIKYKGWQVAPAHLESILLTHPSVSDAAVIPLPDEEAGEIPAACVVMNKDAKEKEEEIMKYVASKVASYEKVRVLRFVGSIPRSHSGKILRRVLKEEMIQTMKNNP
MLSVASLDTTTTSPAPKPAVVDINVTDLQISSNTNIIHDQLTSSSPHHEYQIPKEDHIFKSRLPDINIPNHLSLHTYVFENVPQHPHRTCLIVGSTGITYSFAQTHLISRKVASGLSRLGITKGDVIMVLLQNCAEFVFSFMGASMIGAVTTTANPFYTPAEVFKQFRTSGTKIIITESRYVDKLRNMGDDKYRPIMGQDFKVITINDAPENCLHYSVLSEADENEIDLDSIKIDPEDAVVLPFSSGTTGLPKGVILTHKSQTTSVSQQVDGENPNLHLKEEDVVLCVLPLFHIFSLNSVLLNSLRAGAPVLLMHKFEIFTLLELIQRHKVSVAAVVPPLVLALAKNPAVADYDLSSLRIVLSGAAPLGKELEEALHRRVPQAVFGQGYGMTEAGSVLTMCLSFAKQPTPTKSGSCGTVVRNAELKVVDPDTGRSLPRNQPGEICVRGFQIMKGYLNDPEATAVTIDVDGWLHSGDIGYVDDDDEVFIVDRVKELIKFKGFQVPPAELEALLVNHPSISDAAVVPQKDDAAGEVPVAFVVRSNGFELAEDDVKQFIAKQVVFYKKLHKVYFVTTIPKSPSGKILRKELRARLGTPSPVV
>mRNA8275
MEILNETKPVLSNPLCYSSETGIYSSKYLKMSLPTNPLTDVVSYIFSKKHTGNLALIDSFSGHSIPYSELLPRVKSVASGLRQLGISRGDVVLILLPNSIYFPVILLGVMSIGAVVSPMNPLSSLNEIKKQTLDCRAEVAFTTHTKSQIFDKLGLKTITVPENVDYGFLNNDNFFSSDPNLAPQVNIRQDDTAAIMYSSGTTGTCKGVMLSHKNFISVIELFVRFEASQYDYLASENVYLAVLPMFHIYGMSLFVMGLFTLGGTIVVMRKFEVGEMVKVIDTYKITHFHAVPPLINALTERAKRGEKERLKSLKQVTSGAAPLSRKSADEFVCTLPQVDFIQGYGMTESTAVATRGFNTKKLCNYTSIGLLSPNTEAKVVDIVTGSFMPPGKRGELLLRGPGTMKGYLNNPEATAQAIDKDGWLHTGDIVYFDSDGYIYICDRLKEMIKYKGFQIAPAELESLLISHPDVIDAAVTAAKDEKAGEVPIAFVVKRSGSRLSESALSDYVAKQVSPYKKLRKVVFTQSIPKSAAGKILRRELKTLIPARL
>mRNA24282
METKTRKEEMIFRSKLPDIYIPKHLPLHSYCFENISQVASRPCLINGATGEIHTYADVELTAKKVAAGLDKLGIKQGDTIMILLPNSPEFVFAFIGASYRGAISTMANPFFTAAEVVKQAKASKARLIVTQASYVDKVMEYADDNDIKVICIDTPPEGCLPFSALTDSSPEDVPSVTISPNDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYMNSDDVVMCVLPLFHIYSLNSVLLCSLRVGAAILIMQKFEINSFLGLIEKYKVTIGAFVPPIVLAIAKSPQVDKYDLSTIRLVQSGAAPLGKALEDTVRAKFPNARLGQGYGMTEAGPVLALCLAFAKEPYEIKSGACGSVMRNAEMKIIDPDTGDSLSRNQPGEICIRGDQIMKGYLNDPEATERTIDNEGWLHTGDIGYIDEDDELFIVDRLKELIKYKGFQVPPAELEALLLTHPQISDAAVVPMKDESAGEVPVAFVVKPNGVPITEDEIKQFVAKQVVFYKRICKVFFIDAIPKAPSGKILRKDLRARLAASLAN
>mRNA25922
MVINTQQKEMIFRSKLPDIYIPNHLPLHAYCFENISEFSSKPCLINGATGEIHTYADVEMTSKKVASGLDKHGIRQGDTIMILLPNSPEFVFAFLGASYRGAISTMANPFFTAAEVVKQMKASNAKLVVTQASYVDKLKEYANENDVKIICIDTPPEGCLHFSELINLSDEEPPSVTISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYMHSDDVALCVLPLFHIYSLNSVLLCGLRAGAAILIMQKFEINSFFGLIEKYKVTIGPFVPPIVLAIAKSPVVDDYDMSTIRMVMSGAAPLGKELEDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKKPYEIKSGACGTVVRNAEMKIIDPDTNASLPRNQPGEICIRGDQIMKGYLNDPVATSQTIDKEGWLHTGDIGYIDNDDELFIVDRLKELIKYKGFQVPPAELEALLLTHPKIGDAAVVPMKDESAGEVPVAFVVRSNGYQITEDEIKQFVSKQVVFYKRLSRVFFTDTIPKAPSGKILRKDLRARLAAGLAN
>mRNA15006
MAPILLNQSQDEENIFRSPYKSVEVPENMTLPEFILQNAELYTEKVAFVDISSGKEYTYGQVVRDVKRFANALRSLGLRKGRVVVVVLPNVAEYAIVSLGIMAAGGVFSGANPLAHHSEIKTQVEVADAKLVVTNGTNYDKVKDLGLPIIVLGEERVESAMYWDELLEAADRASTDTINEPIYQTDLCALPFSSGTTGKSKGVMLTHRNLVSNLCSTLFSVGPELVGLVVVLGLMPFFHIYGLVGICCATLRNKGKVVVMERYTLETFMNALILHEVSFAPIVPAVISDMAKNSLVDEFDLSKLNLRAVMTAAAPLAPEVLSGFERKFPGVEVQEAYGMTEHSCITLSHGDPHKGQRRAKKNSVGFVLPNIEVRFVDPNTGRSLPKNTQGEICVRSQCVMKGYYQNEDETAQTIDKDGWLHTGDIGYIDDDGDVFIVDRIKELIKYKGWQVAPAHLESILLTHPSVSDAAVIPLPDEEAGEIPAACVVMNKDAKEKEEEIMKYVASKVASYEKVRVLRFVGSIPRSHSGKILRRVLKEEMIQTMKNNP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University