Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Portulaca amilis
Species name
Portulaca amilis is a species of eudicot in the family Portulacaceae (purslane family).
Species info
Gene sequence info
Portulaca_amilis.4CL.fa
Download
>FUN_025302-T1.v1.0
METRQDENSDQFQEKTQEYIFRSRYKAVPVPDNVTLPEFVLDDVESYSDKVALVDALTGKEYTYGQVSKDTKRFAKALRSLGIRKGHVVIVVLPNVVEYPIVALGIMAAGGVFSGVNPASHASEIRKQVEAADAKLIVTNGTIYDKVKELGLPIIVLGDERIENATAIYWSQLLEAGDKANIRYISEPIHQTDLCALPFSSGTTGMSKGVMLTHRNLVANLCSTLFSVPKEMIGQVTTLGLMPFFHIYGITGICCATLRNKGKVVVMARYELRTFLHALITHQVHFAPVVPPIILALVKNPIVDEFDLSKINLKAIMTAAAPLAPEILTSFENKFPGVQVQEAYGLTEHSCITLTHGDPTQEHGGIAKRNSVGFILPNIEVKFIDPDTGRSLPKNTPGEICVRSQCVMQGYYKNDEETRQTVDSEGWLHTGDIGYIDDDGDVFIVDRIKELIKFKGFQVAPAELEAILLSHPSIEDAAVVPMADEEAGEVPAGCAVKKAGAKESEEDIIKYVASNVAHYKRLRALYFVDSIPKSPSGKIMRRLLKDQIIHLKSNNNTSGSLV
>FUN_044023-T1.v1.0
MAAVETKLLQPDSIPSSSSSSPAAAPSKDHEEQIFRSRFPDISIRNDLPLHSYLFEKLPETADRPCLICGSSVKVYTFAETHLLCRKSGAGLAKLGVKKGDVIMILLQNCPEFVFAFLGASMIGAVSTMANPFYTPAEIAKQLKAAGAKLVVTHAQFVGKLRDNPDVIDGSELTLVTVDEPPEGCLPFSVLTEGNEEELPEVEISPEDAVALPFSSGTTGLPKGVVLTHRSLATSVAQQVDGENPNLNLTADDVALCVLPLFHIFSLNSVLMTGLRAGCAVLIMAKFEIGAFLELIQKHRVSVAMVVPPLVLALAKNAKVDQYDLSSVRIVMSGAAPLGKELEDALRARVPQAVLGQGYGMTEAGPVLSMCPAFAKEPFPTKPGSCGMVVRNADLKVVDPDTRVSLGYNQPGEICIRGQQIMKGYLNDPSATAATIDDQGWLHTGDIGYVDEDHEVFIVDRVKEIIKYKGFQVAPAELEALLVNHPAIADAAVVPQKDEAAGEVPVAFVVRSNGSDEEVSEEQIKEYIAKQVVFYKKLHKVYFVNAIPKSAAGKILRKELRSRLASPPCHSN
>FUN_045242-T1.v1.0
MAAAIQTKPLTHDLPCLSPRHVPTSATTMTNTTTAPTTTTTTPEREHIFKSRLPPIPINNTLPLHSYLFQNLPNHTDRPCLIFGDSTYSYAETYLLCQKTAAGLSNLGVQKGDVVMLLLQNCPEFIFSFFGAAMVGAISTPANPFYTPCEIFKQLKLSNSKLIITQSQFIPKLQSHPEFKLGEDFRVITIDNNSPESCINFSDLANSNQLDIPEIEINPDDPVALPFSSGTTGLPKGVVLTHRSLSTSVSQQVDGENPNLYLKTEDVLLCVLPLFHIFSLNSVLMIALRRGCGILIMSKFEITAMAKLVEKNRVSVAMVVPPLVLALAKNPKAAEYDLSSIRLVMCGAAPLGKELEDELRARIPQAVLGQGYGMTEAGPVLSMCPGFAKEPLPYKAGSCGIVVRNAEMKVIDPDSGASLGYNEPGEICIRGQQIMKGYLNNPEATRATVDAEGWLHTGDIGYVDDDDEVFIVDRVKEIIKYKGFQVAPAELESILINHPSIVDAAVISEKDEAAGEIPVAFVIRYKDAELTEEEVKQYVANKVVFYKKLHKVYFAQTIPKSPSGKILRKELKARIPSKTPSPLAQS
>FUN_026835-T1.v1.0
METIQVIPQQNGYHGPKDHLIHDVVPAVVEKMVINNNNKKKEHVFRSTLPDIYIPDHLPLHDYCFENLEDYRDRPCLIDGPTGRVWSYGEVERTARKVGAGLHARAGVQRRDVIMLLLQNRPEFVLTFLGASFLGAVSTTGNPLCTPAEIEKQVRASGARAIVTQAAFADKVRPYCETNNISLILVDSPPTSPDENSAKAVTHTSSQSIYFWDMAETAESELPQVKPDPDDVVALPYSSGTTGLPKGVMLTHRGLVTSVAQQVDGENPNLYLHKDDVILCVLPLFHIYSLNSVLLCSLRVGAAILIMPKFDILNLMELIQKYKVTVAPFVPPIVLAIAKNQDVDKYDLSSIRIIMSGAAPMGKDLEETLRAKLPNAKLGQGYGMTEAGPVLAMCLAFAKEPVEVKSGSCGTVVRNAELKIVEPETGISLPRNQPGEICIRGSQIMKGYLNDPEATANTIDKDGWLHTGDIGYVDDDDEIFIVDRLKELIKYKGFQVAPAELEGMLVNHPYITDAAVVAMKDEAAGEVPVAFVVKSNGYELTEDDVKQYISKQVVFYKRLNRVFFVDSIPKLASGKILRKELRARLANGISK
>FUN_027826-T1.v1.0
MAMERSGYGRDGIYRSLRPPLVLPTNPNLSMVSFLFRNISSYPHHTALIDAGSGQTLTFSTLKSTVAQLSHGLITQLGLRKGHVVLMLAPNSVQYPVTFLSVIATGAIATTVNPIYTIAEIKKQAQDCKPRMIVCVPELWDKVKDFNLPALILGPKGNIKSSSKVVYFDDLVNGSVVDLPRVYIKQSDTAALLYSSGTTGLSKGVVLTHGNFIASSLMACNDQDSQGEKHNVFLCVIPMFHVFGLAVILYSQLQRGNAVVTMNMDKFDLEMMLGAIEKYKVTNLWIVPTIMLGLAKHGAVKKYDLSSLKQIGSGAAPLGKEIMVECAKIVPQATIIQGLGMTEACGIISLEHPRLGRRHSGSTGMLLPNLEAQIVEVDTSKPLPPKQLGEIWVRGPTMMKGYLNNPQATKMTIDDQGWLHTGDLGYFDEEGQLFVVDRLKELIKYKGFQIAPAEIEAILTSHPQILDAAVIPFPDTEAGEVPVGYVVQSPQSTLKEKDVMKFVSDQVAPYKRLKKMTFCESVPRSPSGKLLRWVLIQQARSKL
>FUN_027897-T1.v1.0
MAMERSGYGRDGIYRSLRPPLILPTNPNLSMVSFLFRNISSYPQHPALIDSGSGQTLTFSTFKSTVAKLSHGLITQLGLQKGHVALVLAPNSVQYPVTFLSIIATGAIATTVNPIYTITEIKKQAQDCKPRLIVCVPELWDKVKDFNLPALILGPKGNMNIKSSSKVVYFDDLVNGSVVDLPRVDIKQSDTAALLYSSGTTGVSKGVVLTHGNFIAASLMACCDQDFEGEKHNVFLCVIPMFHVFGLAVILYSQLQRGNAVVTVDKFDFEMMLAAIEKYKVTNLWVVPPIMLGLAKNGAVRKYDLSSLRQVGSGAAPLGKEIMVECAKNMPQATVIQGYGMTETCGIISLEHPRLGSRHSGSAGILLPSIEARIVKVDTFESLPPKQSGEIWVRGPNMMKGYLNNPQATKMTIDDQGWVHTGDLGYFDEDGQIFVVDRLKELIKYKGFQVAPAELEAILASHPQILEAAVIPFPDTEAGEVPVGYVVRSPQSTLKEEDVMKFVSDQVAPYKRLRKVIFCESIPKAPSGKLLRRVLIQQTQSKL
>FUN_034048-T1.v1.0
MDAKIHSHDENNMHHDENEEYIFRSKLPDIEIPNHLPLHAYCFEKISEFHDRPCLIDGPSGRQWTYAEVEATSRRVGSAFYLELGLEKGEVIMLLLQNCPEFVFSFLGASFIGGISTTANPLCTPAEIQKQARASGARAFVTHAAFADKVRPYCEQNNLPLITIDVPQEPTVNGAYQSRYFWDVVGTAEEPLLPEVEIHPDDVVALPYSSGTTGLPKGVMLTHKSLVTSIAQQVDGENPNLYFHSDDVILCVLPLFHIYSLNSVLLCALRAGAAILVMPKFEIYMLMELIQKYRVTIAPFVPPIVLAIAKNGDVDKYDLSSIRTVLSGAAPMGKDLEDTLRAKLPNAKLGQGYGMTEAGPVLAMCLAFAKEPIEVKSGSCGTVVRNAELKIVDPETGRSLPRNQPGEICIRGSQIMKGYLNDPEATANTIDKDGWLHTGDIGYVDDDDQIFIVDRLKELIKYKGFQVAPAELEGMLLNHPSISDAAVVAMKDEAAGEVPVAFVVRFNGSQITEDEIKQYISKQVVFYKRLNRVFFVDSIPKLPSGKILRKELRARLANGLTK
METRQDENSDQFQEKTQEYIFRSRYKAVPVPDNVTLPEFVLDDVESYSDKVALVDALTGKEYTYGQVSKDTKRFAKALRSLGIRKGHVVIVVLPNVVEYPIVALGIMAAGGVFSGVNPASHASEIRKQVEAADAKLIVTNGTIYDKVKELGLPIIVLGDERIENATAIYWSQLLEAGDKANIRYISEPIHQTDLCALPFSSGTTGMSKGVMLTHRNLVANLCSTLFSVPKEMIGQVTTLGLMPFFHIYGITGICCATLRNKGKVVVMARYELRTFLHALITHQVHFAPVVPPIILALVKNPIVDEFDLSKINLKAIMTAAAPLAPEILTSFENKFPGVQVQEAYGLTEHSCITLTHGDPTQEHGGIAKRNSVGFILPNIEVKFIDPDTGRSLPKNTPGEICVRSQCVMQGYYKNDEETRQTVDSEGWLHTGDIGYIDDDGDVFIVDRIKELIKFKGFQVAPAELEAILLSHPSIEDAAVVPMADEEAGEVPAGCAVKKAGAKESEEDIIKYVASNVAHYKRLRALYFVDSIPKSPSGKIMRRLLKDQIIHLKSNNNTSGSLV
>FUN_044023-T1.v1.0
MAAVETKLLQPDSIPSSSSSSPAAAPSKDHEEQIFRSRFPDISIRNDLPLHSYLFEKLPETADRPCLICGSSVKVYTFAETHLLCRKSGAGLAKLGVKKGDVIMILLQNCPEFVFAFLGASMIGAVSTMANPFYTPAEIAKQLKAAGAKLVVTHAQFVGKLRDNPDVIDGSELTLVTVDEPPEGCLPFSVLTEGNEEELPEVEISPEDAVALPFSSGTTGLPKGVVLTHRSLATSVAQQVDGENPNLNLTADDVALCVLPLFHIFSLNSVLMTGLRAGCAVLIMAKFEIGAFLELIQKHRVSVAMVVPPLVLALAKNAKVDQYDLSSVRIVMSGAAPLGKELEDALRARVPQAVLGQGYGMTEAGPVLSMCPAFAKEPFPTKPGSCGMVVRNADLKVVDPDTRVSLGYNQPGEICIRGQQIMKGYLNDPSATAATIDDQGWLHTGDIGYVDEDHEVFIVDRVKEIIKYKGFQVAPAELEALLVNHPAIADAAVVPQKDEAAGEVPVAFVVRSNGSDEEVSEEQIKEYIAKQVVFYKKLHKVYFVNAIPKSAAGKILRKELRSRLASPPCHSN
>FUN_045242-T1.v1.0
MAAAIQTKPLTHDLPCLSPRHVPTSATTMTNTTTAPTTTTTTPEREHIFKSRLPPIPINNTLPLHSYLFQNLPNHTDRPCLIFGDSTYSYAETYLLCQKTAAGLSNLGVQKGDVVMLLLQNCPEFIFSFFGAAMVGAISTPANPFYTPCEIFKQLKLSNSKLIITQSQFIPKLQSHPEFKLGEDFRVITIDNNSPESCINFSDLANSNQLDIPEIEINPDDPVALPFSSGTTGLPKGVVLTHRSLSTSVSQQVDGENPNLYLKTEDVLLCVLPLFHIFSLNSVLMIALRRGCGILIMSKFEITAMAKLVEKNRVSVAMVVPPLVLALAKNPKAAEYDLSSIRLVMCGAAPLGKELEDELRARIPQAVLGQGYGMTEAGPVLSMCPGFAKEPLPYKAGSCGIVVRNAEMKVIDPDSGASLGYNEPGEICIRGQQIMKGYLNNPEATRATVDAEGWLHTGDIGYVDDDDEVFIVDRVKEIIKYKGFQVAPAELESILINHPSIVDAAVISEKDEAAGEIPVAFVIRYKDAELTEEEVKQYVANKVVFYKKLHKVYFAQTIPKSPSGKILRKELKARIPSKTPSPLAQS
>FUN_026835-T1.v1.0
METIQVIPQQNGYHGPKDHLIHDVVPAVVEKMVINNNNKKKEHVFRSTLPDIYIPDHLPLHDYCFENLEDYRDRPCLIDGPTGRVWSYGEVERTARKVGAGLHARAGVQRRDVIMLLLQNRPEFVLTFLGASFLGAVSTTGNPLCTPAEIEKQVRASGARAIVTQAAFADKVRPYCETNNISLILVDSPPTSPDENSAKAVTHTSSQSIYFWDMAETAESELPQVKPDPDDVVALPYSSGTTGLPKGVMLTHRGLVTSVAQQVDGENPNLYLHKDDVILCVLPLFHIYSLNSVLLCSLRVGAAILIMPKFDILNLMELIQKYKVTVAPFVPPIVLAIAKNQDVDKYDLSSIRIIMSGAAPMGKDLEETLRAKLPNAKLGQGYGMTEAGPVLAMCLAFAKEPVEVKSGSCGTVVRNAELKIVEPETGISLPRNQPGEICIRGSQIMKGYLNDPEATANTIDKDGWLHTGDIGYVDDDDEIFIVDRLKELIKYKGFQVAPAELEGMLVNHPYITDAAVVAMKDEAAGEVPVAFVVKSNGYELTEDDVKQYISKQVVFYKRLNRVFFVDSIPKLASGKILRKELRARLANGISK
>FUN_027826-T1.v1.0
MAMERSGYGRDGIYRSLRPPLVLPTNPNLSMVSFLFRNISSYPHHTALIDAGSGQTLTFSTLKSTVAQLSHGLITQLGLRKGHVVLMLAPNSVQYPVTFLSVIATGAIATTVNPIYTIAEIKKQAQDCKPRMIVCVPELWDKVKDFNLPALILGPKGNIKSSSKVVYFDDLVNGSVVDLPRVYIKQSDTAALLYSSGTTGLSKGVVLTHGNFIASSLMACNDQDSQGEKHNVFLCVIPMFHVFGLAVILYSQLQRGNAVVTMNMDKFDLEMMLGAIEKYKVTNLWIVPTIMLGLAKHGAVKKYDLSSLKQIGSGAAPLGKEIMVECAKIVPQATIIQGLGMTEACGIISLEHPRLGRRHSGSTGMLLPNLEAQIVEVDTSKPLPPKQLGEIWVRGPTMMKGYLNNPQATKMTIDDQGWLHTGDLGYFDEEGQLFVVDRLKELIKYKGFQIAPAEIEAILTSHPQILDAAVIPFPDTEAGEVPVGYVVQSPQSTLKEKDVMKFVSDQVAPYKRLKKMTFCESVPRSPSGKLLRWVLIQQARSKL
>FUN_027897-T1.v1.0
MAMERSGYGRDGIYRSLRPPLILPTNPNLSMVSFLFRNISSYPQHPALIDSGSGQTLTFSTFKSTVAKLSHGLITQLGLQKGHVALVLAPNSVQYPVTFLSIIATGAIATTVNPIYTITEIKKQAQDCKPRLIVCVPELWDKVKDFNLPALILGPKGNMNIKSSSKVVYFDDLVNGSVVDLPRVDIKQSDTAALLYSSGTTGVSKGVVLTHGNFIAASLMACCDQDFEGEKHNVFLCVIPMFHVFGLAVILYSQLQRGNAVVTVDKFDFEMMLAAIEKYKVTNLWVVPPIMLGLAKNGAVRKYDLSSLRQVGSGAAPLGKEIMVECAKNMPQATVIQGYGMTETCGIISLEHPRLGSRHSGSAGILLPSIEARIVKVDTFESLPPKQSGEIWVRGPNMMKGYLNNPQATKMTIDDQGWVHTGDLGYFDEDGQIFVVDRLKELIKYKGFQVAPAELEAILASHPQILEAAVIPFPDTEAGEVPVGYVVRSPQSTLKEEDVMKFVSDQVAPYKRLRKVIFCESIPKAPSGKLLRRVLIQQTQSKL
>FUN_034048-T1.v1.0
MDAKIHSHDENNMHHDENEEYIFRSKLPDIEIPNHLPLHAYCFEKISEFHDRPCLIDGPSGRQWTYAEVEATSRRVGSAFYLELGLEKGEVIMLLLQNCPEFVFSFLGASFIGGISTTANPLCTPAEIQKQARASGARAFVTHAAFADKVRPYCEQNNLPLITIDVPQEPTVNGAYQSRYFWDVVGTAEEPLLPEVEIHPDDVVALPYSSGTTGLPKGVMLTHKSLVTSIAQQVDGENPNLYFHSDDVILCVLPLFHIYSLNSVLLCALRAGAAILVMPKFEIYMLMELIQKYRVTIAPFVPPIVLAIAKNGDVDKYDLSSIRTVLSGAAPMGKDLEDTLRAKLPNAKLGQGYGMTEAGPVLAMCLAFAKEPIEVKSGSCGTVVRNAELKIVDPETGRSLPRNQPGEICIRGSQIMKGYLNDPEATANTIDKDGWLHTGDIGYVDDDDQIFIVDRLKELIKYKGFQVAPAELEGMLLNHPSISDAAVVAMKDEAAGEVPVAFVVRFNGSQITEDEIKQYISKQVVFYKRLNRVFFVDSIPKLPSGKILRKELRARLANGLTK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University