Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Populus alba
Species name
White poplar (Populus alba) is a species of eudicot in the family Salicaceae (willow family).
Species info
Gene sequence info
Populus_alba.COMT.fa
Download
>rna-XM_035047893.1
MATSTGEEDHHLQYAMQLSSASVLPLVLKAAIELGVFEIIEKAGPDALLSASDIVAQFPTQNNPEAHVLLDRSLCLLASHSVLTCSVSTKNIQDGHSQRLYGLAPVAKYFTKNKDGGSLSPFLAMIHDKVMMDMWYSLKVAVLEGGIPFEKAHGINSAEYLKKDARFCELFSSSMKSFNVTFMETILDIYDGFEGVKCLVDVGGGNGSILNMIITKYPAIKGINYDLASVVESSPSYPGIEHVAGDGFVTIPKGGDAIFMKWITHNWDDEHLLKMLKNCYEALPDNGKVIVVDMVVPETPETNVKAKSMLQNYLFITSMSPQGKERTEKEFETLGKEAGFSHIRVACFVCNFSVVEFIKI
>rna-XM_035048384.1
MVGVHLASGFYLKINQPPPRTNMGSFIESHSGQVDEAKDDDFGYAMQLALSSVLPMTMYSAIQLGIFEIIAKAGPDAKLSASDVAAQLPTKNPGAPMMLDRILRLLASHDVLVCSVDGSERLYSLASVSKHFVRNKDGVSLGPFMALIQDNVFLQSWSQLKDAVLEGGVAFDRVHGAHAFEYPGLDPRFNQVFNTAMYNQTTVVLENMLEAYTGFKNLKQLVEIGGGMGHTIKAIISKYPHIKGINFDLPHVIDHAPPCPGVEHVGGDMFESVPKGDAIFLKWILHDWSDDHCLKLLKNCYEAIPDNGKVIVMESVLSIAAKTSHSARAISQLDVLMMTQNPGGKERTEDEFMALATGAGFRGIKYEAFVCNFWVMEFFK
>rna-XM_035048385.1
MARNKNKQKNQKHGASQSMPMAASVTEEETTHNDNNKKTVEEERESFTCAMRLVNASVLPLALKTVVDLGVLDVLSMADPDVGLTAAEISERVPTRNPEAPGMLERILRLLMNEGVVYCSSQLFDEAPMKYRLGRVGKCFVRDENGVSLAPLMALAHDKVYLETWSHLKDAILEGGTPFNRAHGTHLFEYSARDARFSQVYNTAMSNHTTLVFKKMLESYRGFENLKQVVDVGGGIGVALSLITFKYPFINAINFDLPHVIQHAPPFPGVKHVEGDMFKSVPKGDAIILKWILRDWDDEHCLKLLKNCYMSVPVDGKIIVVEQILPTFAEITAVSKDKSQLDMVSLTQTPGGKERMQGDLFNLAFSAGFKGVSLVSYVYHYWVMEFLK
>rna-XM_035050147.1
MATSSNEEEDYHLQYALQLASASTLPMVFKAVIELGVLEIIEKAGPGALLSASQIASQLPTQNNPDAPIVLDRILCLLASHSILTCSLATENQDSDQVQRLYGLAPVAKYFIKKEDGGSLSPYFLVIQDKVTVDLWYHLKDVILQGGALFQKAYGMSSMEYVKKDPRFGEVFSGFVKGFNPLFMKRILDIYDGFEGLTSLVDVGGGNGSVLNMIISKYPAIKGINFDLAPVIENSPSYPGIEHVAGDVFLTIPKGEAIFMKWVSHFWNDENFLKVLKNCYEALPDTGKLIVVEMVIPEIPGTSGADRSLLQNYLFVTNMNPKRNERTEKEFERLAKGAGFSHLRVACSACSFSVVEFIKKKATASTAATAAK
>rna-XM_035052073.1
MDSTGETQMSPAQILDEEANFAMQLISSSVLPMVLKTAIELDLLEIMAKAGPGALLSPSDIASHLPTKNPDAPVMLDRILRLLASYSILVCSLRDLPDGKVERLYGLASVCKFLTKNEDGVSVNPLCLMNQDKFLMESWYHLKDAILEGGIPFNKAYGMTAFEYHGTDPRFNKVFNKGMSDHSKMAMKKILETYKGFEGLASLVDVGGGTGAVVSTIVSKYPSIKGINFDLPHVIADAPAFPGVENVGGDMFVSVPKADAVFMKWICHDWSDEHCLRFLKNCYDALPENGKVILVECILPVAPDTSLATKGVMHVDAIMLAHYPGGKERTDKEFEGLARGAGFKSFEVMCCAFNTHVIEFRKQA
>rna-XM_035052072.1
MGSTGETQMSPAQILDEEANFAMQLISSSVLPMVLKTAIELDLLEIMAKAGPGALLSPSDIASHLPTKNPDAPVMLDRILRLLASYSILVCSLRDLPDGKVERLYGLASVCKFLTKNEDGASVSPLCLMNQDKVLMESWYHLKDAILEGGIPFNKAYGMTAFEYHGTDPRFNKVFNKGMSDHSKMAMKKILETYKGFEGLASLVDVGGGTGAVVSTIVSKYPSIKGINFDLPHVIADAPAFPGVENVGGDMFVSVPKADAVFMKWICHDWSDEHCLRLLKNCYDALPENGKVILVECILPVAPDTSLATKGVMHVDAIMLAHNPGGKERTDKEFEGLARGAGFKGFEVMCCAFNTHVIEFRKQA
>rna-XM_035058022.1
MALNEESAEKRKSARLVIFELANMISVPMSLNAIVRLKVADAIWQGGSNAPLSASQILQRIASTGSDPENLQRILRMLTSYGVFEEHLTIESSPLDGSASARKYSLTEVGKTLVTDTEGLSYAPYVLQHHQDALMKAWPLVHEAVLDPTTEPFVKANGEPAYDYYGKQPEMNELMLKAMSGVSVPFMEAMLDGYDGFKGVERLVDVGGSAGDCLRMILKKHPGVRQGINFDLPEVVAKAPIIPGVTNVGGDMFKSIPDGDAIFMKWILTTWTDNECKLIMENCYKALPVGGKLIACEPVLPKDSDDSHRTRALLEGDIFVMTIYRAKGKHRTEEEFKQLGQSVGFSHFRAFYVDYFYTVLEFQK
>rna-XM_035077389.1
MATSSNEEDYHLQYALQLASASTLPMIFKAVIELGVLEIIEKAGPGALLSASQIASQLPTQNNPDAPIVLDRILCLLASHSILTCSLATENQDSDQVQRLYGLAPVANYFIKKEDGGSLSPYFLVIQDKVTVDLWYHLKDVILQGGVLFQKAYGMSSMEYVKKDPRFGELFSGFVKGFNPLFMKRILDIYDGFEGLTSLVDVGGGNGSVLNMIISKYPAIKGINFDLAPVIENSPSYPGIEHVAGDVFLTIPKGEAIFMKWVSHFWNDENFLKVLKNCYEALPDTGKLIVVEMVIPESPGTSVADRSLLQNYLFVTNMNPKRNERTEKEFERLAKGAGFSHLRVACSACSFSVVEFIKKKATASTAATAAK
>rna-XM_035077515.1
MASSIENHVSQVDEAKDENFGYAMQLALSSVLPMTLHTAIQLGIFEIITKAGPDVKLSAADIAAKLPTDNPDTPKMLDRILRLLASHQVLCCFVDGSERFYSLAPVSKYFVRNQNGVSLAPFMAMIQENVILQGWSQLKDAVLEGGVAFVRVHGVQAFEYPGLDPRFNQVFNTAMCNQTTIVNGHMLEKYDGFKNLKQLVDIGGGLGHTLKAVTSKYPQIKGINFDLPHVIEHAPAYPGVEHVGGDMFESVPKGDAIFLKWILHNWSDDHCLKLLKNCYKAIPEDGKVIVMESVLPITAKTSPAAKAISQLDVMMMMTQNPGGKERTEDEFMALATAAGFRGIKFETFVCHFWVMEFFK
>rna-XM_035077516.1
MASSIENHASQVDEAKDENFGYAMQLALSSVLPMTLHTAIQLGIFEIIAKAGPDVKLSAANIAAKLPTDNPDTPKMLDRILRLLASHQVLCCFVDGSERFYSLAPVSKYFVRNQNGVSLAPFMAMIQENVILQGWSQLKDAVLEGGVAFVRVHGVQAFEYPGLDPRFNQVFNTAMYNQTTIVNGHMLEKYDGFKNLKQLVDIGGGLGHTLKAVTSKYPQIKGINFDLPHVIEHAPAYPGVEHVGGDMFESVPKGDAIFLKWILHNWSDDHCLKLLKNCYKAIPEDGKVIVMESVLPITAKTSPAAKAISQLDVMMMMSQNPGGKERTEDEFMALATAAGFRGIKFETFVCHFWVMEFFK
>rna-XM_035033152.1
MYPVMRYHFNDAILKGSVPFNRAYGMTAFQYPGTDQRFNRVFNQAMPNHTPFIMKKILDIYEGLDGLEVLVDVGGGIGDTLNIITSKYPHIEGRNYNMPHILADAPSYPGTIAFFCFNSTVQVRLYPSCILMQFAL
>rna-XM_035043911.1
MGSTGETQMTPTQVSDEEAHLFAMQLASASVLPMILKTAIELDLLEIMAKAGPGAFLSTSEIASHLPTKNPDAPVMLDRILRLLASYSILTCSLKDLPDGKVERLYGLAPVCKFLTKNEDGVSVSPLCLMNQDKVLMESWYYLKDAILEGGIPFNKAYGMTAFEYHGTDPRFNKVFNKGMSDHSTITMKKILETYKGFEGLTSLVDVGGGTGAVVNTIVSKYPSIKGINFDLPHVIEDAPSFPGVEHVGGDMFVSVPKADAVFMKWICHDWSDAHCLKFLKNCYDALPENGKVILVECILPVAPDTSLATKGVVHVDVIMLAHNPGGKERTEKEFEGLAKGAGFQGFEVMCCAFNTHVIEFRKKA
MATSTGEEDHHLQYAMQLSSASVLPLVLKAAIELGVFEIIEKAGPDALLSASDIVAQFPTQNNPEAHVLLDRSLCLLASHSVLTCSVSTKNIQDGHSQRLYGLAPVAKYFTKNKDGGSLSPFLAMIHDKVMMDMWYSLKVAVLEGGIPFEKAHGINSAEYLKKDARFCELFSSSMKSFNVTFMETILDIYDGFEGVKCLVDVGGGNGSILNMIITKYPAIKGINYDLASVVESSPSYPGIEHVAGDGFVTIPKGGDAIFMKWITHNWDDEHLLKMLKNCYEALPDNGKVIVVDMVVPETPETNVKAKSMLQNYLFITSMSPQGKERTEKEFETLGKEAGFSHIRVACFVCNFSVVEFIKI
>rna-XM_035048384.1
MVGVHLASGFYLKINQPPPRTNMGSFIESHSGQVDEAKDDDFGYAMQLALSSVLPMTMYSAIQLGIFEIIAKAGPDAKLSASDVAAQLPTKNPGAPMMLDRILRLLASHDVLVCSVDGSERLYSLASVSKHFVRNKDGVSLGPFMALIQDNVFLQSWSQLKDAVLEGGVAFDRVHGAHAFEYPGLDPRFNQVFNTAMYNQTTVVLENMLEAYTGFKNLKQLVEIGGGMGHTIKAIISKYPHIKGINFDLPHVIDHAPPCPGVEHVGGDMFESVPKGDAIFLKWILHDWSDDHCLKLLKNCYEAIPDNGKVIVMESVLSIAAKTSHSARAISQLDVLMMTQNPGGKERTEDEFMALATGAGFRGIKYEAFVCNFWVMEFFK
>rna-XM_035048385.1
MARNKNKQKNQKHGASQSMPMAASVTEEETTHNDNNKKTVEEERESFTCAMRLVNASVLPLALKTVVDLGVLDVLSMADPDVGLTAAEISERVPTRNPEAPGMLERILRLLMNEGVVYCSSQLFDEAPMKYRLGRVGKCFVRDENGVSLAPLMALAHDKVYLETWSHLKDAILEGGTPFNRAHGTHLFEYSARDARFSQVYNTAMSNHTTLVFKKMLESYRGFENLKQVVDVGGGIGVALSLITFKYPFINAINFDLPHVIQHAPPFPGVKHVEGDMFKSVPKGDAIILKWILRDWDDEHCLKLLKNCYMSVPVDGKIIVVEQILPTFAEITAVSKDKSQLDMVSLTQTPGGKERMQGDLFNLAFSAGFKGVSLVSYVYHYWVMEFLK
>rna-XM_035050147.1
MATSSNEEEDYHLQYALQLASASTLPMVFKAVIELGVLEIIEKAGPGALLSASQIASQLPTQNNPDAPIVLDRILCLLASHSILTCSLATENQDSDQVQRLYGLAPVAKYFIKKEDGGSLSPYFLVIQDKVTVDLWYHLKDVILQGGALFQKAYGMSSMEYVKKDPRFGEVFSGFVKGFNPLFMKRILDIYDGFEGLTSLVDVGGGNGSVLNMIISKYPAIKGINFDLAPVIENSPSYPGIEHVAGDVFLTIPKGEAIFMKWVSHFWNDENFLKVLKNCYEALPDTGKLIVVEMVIPEIPGTSGADRSLLQNYLFVTNMNPKRNERTEKEFERLAKGAGFSHLRVACSACSFSVVEFIKKKATASTAATAAK
>rna-XM_035052073.1
MDSTGETQMSPAQILDEEANFAMQLISSSVLPMVLKTAIELDLLEIMAKAGPGALLSPSDIASHLPTKNPDAPVMLDRILRLLASYSILVCSLRDLPDGKVERLYGLASVCKFLTKNEDGVSVNPLCLMNQDKFLMESWYHLKDAILEGGIPFNKAYGMTAFEYHGTDPRFNKVFNKGMSDHSKMAMKKILETYKGFEGLASLVDVGGGTGAVVSTIVSKYPSIKGINFDLPHVIADAPAFPGVENVGGDMFVSVPKADAVFMKWICHDWSDEHCLRFLKNCYDALPENGKVILVECILPVAPDTSLATKGVMHVDAIMLAHYPGGKERTDKEFEGLARGAGFKSFEVMCCAFNTHVIEFRKQA
>rna-XM_035052072.1
MGSTGETQMSPAQILDEEANFAMQLISSSVLPMVLKTAIELDLLEIMAKAGPGALLSPSDIASHLPTKNPDAPVMLDRILRLLASYSILVCSLRDLPDGKVERLYGLASVCKFLTKNEDGASVSPLCLMNQDKVLMESWYHLKDAILEGGIPFNKAYGMTAFEYHGTDPRFNKVFNKGMSDHSKMAMKKILETYKGFEGLASLVDVGGGTGAVVSTIVSKYPSIKGINFDLPHVIADAPAFPGVENVGGDMFVSVPKADAVFMKWICHDWSDEHCLRLLKNCYDALPENGKVILVECILPVAPDTSLATKGVMHVDAIMLAHNPGGKERTDKEFEGLARGAGFKGFEVMCCAFNTHVIEFRKQA
>rna-XM_035058022.1
MALNEESAEKRKSARLVIFELANMISVPMSLNAIVRLKVADAIWQGGSNAPLSASQILQRIASTGSDPENLQRILRMLTSYGVFEEHLTIESSPLDGSASARKYSLTEVGKTLVTDTEGLSYAPYVLQHHQDALMKAWPLVHEAVLDPTTEPFVKANGEPAYDYYGKQPEMNELMLKAMSGVSVPFMEAMLDGYDGFKGVERLVDVGGSAGDCLRMILKKHPGVRQGINFDLPEVVAKAPIIPGVTNVGGDMFKSIPDGDAIFMKWILTTWTDNECKLIMENCYKALPVGGKLIACEPVLPKDSDDSHRTRALLEGDIFVMTIYRAKGKHRTEEEFKQLGQSVGFSHFRAFYVDYFYTVLEFQK
>rna-XM_035077389.1
MATSSNEEDYHLQYALQLASASTLPMIFKAVIELGVLEIIEKAGPGALLSASQIASQLPTQNNPDAPIVLDRILCLLASHSILTCSLATENQDSDQVQRLYGLAPVANYFIKKEDGGSLSPYFLVIQDKVTVDLWYHLKDVILQGGVLFQKAYGMSSMEYVKKDPRFGELFSGFVKGFNPLFMKRILDIYDGFEGLTSLVDVGGGNGSVLNMIISKYPAIKGINFDLAPVIENSPSYPGIEHVAGDVFLTIPKGEAIFMKWVSHFWNDENFLKVLKNCYEALPDTGKLIVVEMVIPESPGTSVADRSLLQNYLFVTNMNPKRNERTEKEFERLAKGAGFSHLRVACSACSFSVVEFIKKKATASTAATAAK
>rna-XM_035077515.1
MASSIENHVSQVDEAKDENFGYAMQLALSSVLPMTLHTAIQLGIFEIITKAGPDVKLSAADIAAKLPTDNPDTPKMLDRILRLLASHQVLCCFVDGSERFYSLAPVSKYFVRNQNGVSLAPFMAMIQENVILQGWSQLKDAVLEGGVAFVRVHGVQAFEYPGLDPRFNQVFNTAMCNQTTIVNGHMLEKYDGFKNLKQLVDIGGGLGHTLKAVTSKYPQIKGINFDLPHVIEHAPAYPGVEHVGGDMFESVPKGDAIFLKWILHNWSDDHCLKLLKNCYKAIPEDGKVIVMESVLPITAKTSPAAKAISQLDVMMMMTQNPGGKERTEDEFMALATAAGFRGIKFETFVCHFWVMEFFK
>rna-XM_035077516.1
MASSIENHASQVDEAKDENFGYAMQLALSSVLPMTLHTAIQLGIFEIIAKAGPDVKLSAANIAAKLPTDNPDTPKMLDRILRLLASHQVLCCFVDGSERFYSLAPVSKYFVRNQNGVSLAPFMAMIQENVILQGWSQLKDAVLEGGVAFVRVHGVQAFEYPGLDPRFNQVFNTAMYNQTTIVNGHMLEKYDGFKNLKQLVDIGGGLGHTLKAVTSKYPQIKGINFDLPHVIEHAPAYPGVEHVGGDMFESVPKGDAIFLKWILHNWSDDHCLKLLKNCYKAIPEDGKVIVMESVLPITAKTSPAAKAISQLDVMMMMSQNPGGKERTEDEFMALATAAGFRGIKFETFVCHFWVMEFFK
>rna-XM_035033152.1
MYPVMRYHFNDAILKGSVPFNRAYGMTAFQYPGTDQRFNRVFNQAMPNHTPFIMKKILDIYEGLDGLEVLVDVGGGIGDTLNIITSKYPHIEGRNYNMPHILADAPSYPGTIAFFCFNSTVQVRLYPSCILMQFAL
>rna-XM_035043911.1
MGSTGETQMTPTQVSDEEAHLFAMQLASASVLPMILKTAIELDLLEIMAKAGPGAFLSTSEIASHLPTKNPDAPVMLDRILRLLASYSILTCSLKDLPDGKVERLYGLAPVCKFLTKNEDGVSVSPLCLMNQDKVLMESWYYLKDAILEGGIPFNKAYGMTAFEYHGTDPRFNKVFNKGMSDHSTITMKKILETYKGFEGLTSLVDVGGGTGAVVNTIVSKYPSIKGINFDLPHVIEDAPSFPGVEHVGGDMFVSVPKADAVFMKWICHDWSDAHCLKFLKNCYDALPENGKVILVECILPVAPDTSLATKGVVHVDVIMLAHNPGGKERTEKEFEGLAKGAGFQGFEVMCCAFNTHVIEFRKKA
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University