Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Populus alba
Species name
White poplar (Populus alba) is a species of eudicot in the family Salicaceae (willow family).
Species info
Gene sequence info
Populus_alba.4CL.fa
Download
>rna-XM_035074470.1
MGTPIPCSEQEGHIFRSRHPAVPVPDITLPDFVLQDAELYADDVAFVEAATGKTFTYAEVVRDTRRFAKALRSLGLRKGHVVVVALPNVAEYGIVALGIMAAGGVFSGANPTAHESELKKQAEAADAKLIVTNDLNYGKVKGLGLPVIVLGEVRISTAVNWNELLDAADRAGDTLAYEEVLQSDLCALPFSSGTTGMSKGVMLTHRNLVANLCSSLFSVGPEMMGQVATLGLIPFFHIYGITGICCATLRNKGKVVVMGRFELRTFLNALITQEVSFAPIVPPIILALVKNPIVEEFDLSKLKLKAIMTAAAPLAPELLTAFENKFPGVQVQEAYGLTEHSCITLTHGDPSKGHGIAKKNSVGFLLPNLEIKFINPENGQSLPENTPGEICVRSQCVMQGYYNNKEETARTIDADGWLHTGDIGYIDNDGDIFIVDRIKELIKYKGFQVAPAELEAILLAHPSVEDAAVVPLPDEEAGEIPAACVVMSKGAKESEDDIMEFVASNVAHYKKVRVVQFVDSIPKSPSGKIMRRLLKDKMGTRSKAS
>rna-XM_035050694.1
MMSVATVEPPKPELSPPQNQNAPSSHETDHIFRSKLPDITISNHLPLHAYCFENLSDFSDRPCLISGSTGKTYSFAETHLISRKVAAGLSDLGIKKGDVIMTLLQNCPEFVFSFMGASMIGAVTTTANPFYTQSEIFKQFSASRAKLIITQSQYVNKLGDSDCHENNQKPGEDFIVITIDDPPENCLHFNVLVEANESEMPTVSILPDDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGEIPNLYLKQDDVVLCVLPLFHIFSLNSVLLCSLRAGSAVLLMQKFEIGSLLELIQKHNVSVAAVVPPLVLALAKNPLVANFDLSSIRVVLSGAAPLGKELEDALRSRVPQAILGQGYGMTEAGPVLSMCLAFSKQPFPTKSGSCGTVVRNAELKVIDPETGRSLGYNQPGEICIRGSQIMKGYLNDAEATANTIDVEGWLHTGDIGYVDDDDEIFIVDRVKEIIKFKGFQVPPAELEALLVNHPSIADAAVVPQKDEVAGEVPVAFVVRSDELDLSEEAVKDYIAKQVVFYKKLHKVFFVHSIPKSASGKILRKDLRAKLATATTMS
>rna-XM_035065378.1
MDAIMNPQEEFIFRSKLPDIYIPKNLPLHSYVLENLSNHSSKPCLINGANGDVYTYADVELTARRVASGLNKIGIQQGDVIMLFLPSSPEFVLAFLGASHRGAIITAANPFSTPAELAKHAKASRAKLLITQACYYEKVKDFARESDVKVMCVDSAPDGCLHFSELTQADENEAPQVDISPDDVVALPYSSGTTGLPKGVMLTHKGLITSVAQQVDGDNPNLYFHSEDVILCVLPMFHIYALNSIMLCGLRVGASILIMPKFEIGSLLGLIEKYKVSIAPVVPPVMMSIAKSPDLDKHDLSSLRMIKSGGAPLGKELEDTVRAKFPQARLGQGYGMTEAGPVLAMCLAFAKEPFDIKPGACGTVVRNAEMKIVDPETGASLPRNQPGEICIRGDQIMKGYLNDPEATSRTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIAHPEISDAAVVGLKDEDAGEVPVAFVVKSEKSQATEDDIKQYISKQVIFYKRIKRVFFIEAIPKAPSGKILRKNLKEKLAGI
>rna-XM_035066388.1
MDTITKQKEEFIFRSKLPDIDIPRGLPLHSYVFENFSKYPSKPCLINGANGDIYTYSDVELTARRAASGLNKLGIQQGDVIMLILPSSPEFVLAFLGASHRGAITTAANPFSTPAELAKQAKASKAKLLITQACYYDKVKDYAQENDVKVMCVDSAPDACLHFSDLTQADGDDMPQVDISPDDVVALPYSSGTTGLPKGVMLTHRGLITSVAQQVDGDNPNLYFHREDVILCVLPMFHIYALNSIMLCGLRAGAAILIMPKFEIGSLLGLIEKYKVSIAPVVPPVMLAIAKSPDLDKHDLSSLRMLKSGGSPLGKELEDTVRAKFPQARLGQGYGMTEAGPVLAMCLAFAKEPFDIKPGACGTVVRNAEMKIVDPETGSSLPRNLPGEICIRGDQIMKGYLNDPEATSRTIDNDGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEALLQAHTGISEAAVVGMKDEDAGEIPVAFVIKSENSQVTEEEIMQYISKQVIFYKKIKRVFFVEAIPKAPSGKILRKNLRERLAGGLQK
>rna-XM_035068064.1
MEKSGYGRDGIYRSLRPKLVLPKDPNLSLVSFLFRNSNSYPHKPALIDADLSITLSFSELKSIVIKVAHGLLNLGITKNDVVLIFAPNSYQFPICFLAITSTGAIATTANPLYTTSELSKQIKDSNPKLIITVPELWDKVKGFNLPAVFLGPKRVSLPLESGSRITSFDSLVGLGGSNSQFPSSNVKQSDISTLLYSSGTTGVSKGVILTHGNFIAASLMVTMDQVTAGEMNHVFLCFLPMFHVFGLAVITYSQLQMGNAVVSMGKFEFEMVLKNIEKHRVTHMWVVPPVVLALAKQDVVKKYDLSSLRNIGSGAAPLGKDLMKECAKNMPDTIISQGYGMTETCGIVSVEDSRLGVRHSGSAGMLAAGIEAQIVSVETLKPLPPNQLGEIWVRGPNMMRGYFNNPQATKDTIDKKGWVHTGDLGYFDDDGQIFVVDRIKELIKYKGFQVAPAELEGLLVSHPQILDAVVIPYPDAEAGEVPVAYVVRSPNSALTEVDVQKFIADQVAPFKRLRKVTFINTVPKSASGKILRRELIQQVKSKI
>rna-XM_035076520.1
MEANKDQAKEFIFRSKLPDIYIANHLPLHTYCFEKLSQFKDNPCLINGPTGDIYTYADVELTSRKVASGLYRLGLQQGDVILLLLQNSPEFVFAFLGASFIGAISSTGNPFYTSAEIAKQATASKAKLIITQAAFAEKVQQFAQENDHVKIMTIDSLTDNCLHFSELTSSDENEIPAVKIKPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHERDVILCVLPLFHIYSLNSVFLCGLRAGSAILLMQKFETVALMDLVQKYKVTIAPLVPPIFLAIAKSPVVDQYDLSSIRTVLSGAAPMGKELEDTVRAKLPNAKLGQGYGMTEAGPVIAMCLAFAKEPFEVKSGACGTVVRNAEMKIVDPETGDSQPRNKAGEICIRGSQIMKGYLNDPEATERTIDKDGWLHTGDIGYIDEDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPSISDAAVVPMKDEAAGEVPVAFVVRSNGSKITEDEIKQYISKQVIFYKRIGRVFFTEAIPKAPSGKILRKDLRARVSAGDIPHQIPNMQNQH
>rna-XM_035037180.1
MEAVNDQAQEFIFRSKLPDIQIPNDLPLHTYCFENLSRFKDNPCLINGPTGEIHTYTDVELTSRKVASGLSKLGIKQGDVILLLLQNSPEFVFAFLGASIIGAISTTANPFYTPSEVAKQATASKAKLIITQAVYAEKVQQFIKENDHVKLVTVDSPPENYLHFSELTNSDEDDIPAVEINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHEKDVILCVLPLFHIYSLNSVLLCGLRVGSAILLMQKFEIVTLMELVQKYKVTIAPFVPPIVLAVAKCPVVDKYDLSSIRTVMSGAAPMGKELEDTVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDTGRSLPRNQAGEICIRGSQIMKGYLNDSEATERTIDNDGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHHDIFDCAVVPMKDEAAGEVPVAFVVRANGSKITEDEIKQFISKQVVFYKRISRVFFTESIPKAPSGKILRKDLRARLATGDLPH
>rna-XM_035042016.1
MDTITKQKEEFIFRSKLPDIDIPRGLPLHSYVFENFSKYPSKPCLINGANGDIYTYSDVELTARRAASGLNKLGIQQGDVIMLILPSSPEFVLAFLGASHRGAITTAANPFSTPAELAKQAKASKAKLLITQACYYDKVKDYAQENDVKVMCVDSAPDVCLHFSDLTQADDDDMPQVDISPDDVVALPYSSGTTGLPKGVMLTHRGLITSVAQQVDGDNPNLYFHREDVILCVLPMFHIYALNSIMLCGLRAGAAILIMPKFEIGSLLGLIEKYKVSIAPVVPPVMLAIAKSPDLDKHDLSSLRMLKSGGSPLGKELEDTVRAKFPQARLGQGYGMTEAGPVLAMCLAFAKEPFDIKPGACGTVVRNAEMKIVDPETGSSLPRNLPGEICIRGDQIMKGYLNDPEATSRTIDNDGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEALLQAHTGISEAAVVGMKDEDAGEIPVAFVIKSENSQVTEEEIMQYISKQVIFYKKIKRVFFVEAIPKAPSGKILRKNLRERLAGGLQK
MGTPIPCSEQEGHIFRSRHPAVPVPDITLPDFVLQDAELYADDVAFVEAATGKTFTYAEVVRDTRRFAKALRSLGLRKGHVVVVALPNVAEYGIVALGIMAAGGVFSGANPTAHESELKKQAEAADAKLIVTNDLNYGKVKGLGLPVIVLGEVRISTAVNWNELLDAADRAGDTLAYEEVLQSDLCALPFSSGTTGMSKGVMLTHRNLVANLCSSLFSVGPEMMGQVATLGLIPFFHIYGITGICCATLRNKGKVVVMGRFELRTFLNALITQEVSFAPIVPPIILALVKNPIVEEFDLSKLKLKAIMTAAAPLAPELLTAFENKFPGVQVQEAYGLTEHSCITLTHGDPSKGHGIAKKNSVGFLLPNLEIKFINPENGQSLPENTPGEICVRSQCVMQGYYNNKEETARTIDADGWLHTGDIGYIDNDGDIFIVDRIKELIKYKGFQVAPAELEAILLAHPSVEDAAVVPLPDEEAGEIPAACVVMSKGAKESEDDIMEFVASNVAHYKKVRVVQFVDSIPKSPSGKIMRRLLKDKMGTRSKAS
>rna-XM_035050694.1
MMSVATVEPPKPELSPPQNQNAPSSHETDHIFRSKLPDITISNHLPLHAYCFENLSDFSDRPCLISGSTGKTYSFAETHLISRKVAAGLSDLGIKKGDVIMTLLQNCPEFVFSFMGASMIGAVTTTANPFYTQSEIFKQFSASRAKLIITQSQYVNKLGDSDCHENNQKPGEDFIVITIDDPPENCLHFNVLVEANESEMPTVSILPDDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGEIPNLYLKQDDVVLCVLPLFHIFSLNSVLLCSLRAGSAVLLMQKFEIGSLLELIQKHNVSVAAVVPPLVLALAKNPLVANFDLSSIRVVLSGAAPLGKELEDALRSRVPQAILGQGYGMTEAGPVLSMCLAFSKQPFPTKSGSCGTVVRNAELKVIDPETGRSLGYNQPGEICIRGSQIMKGYLNDAEATANTIDVEGWLHTGDIGYVDDDDEIFIVDRVKEIIKFKGFQVPPAELEALLVNHPSIADAAVVPQKDEVAGEVPVAFVVRSDELDLSEEAVKDYIAKQVVFYKKLHKVFFVHSIPKSASGKILRKDLRAKLATATTMS
>rna-XM_035065378.1
MDAIMNPQEEFIFRSKLPDIYIPKNLPLHSYVLENLSNHSSKPCLINGANGDVYTYADVELTARRVASGLNKIGIQQGDVIMLFLPSSPEFVLAFLGASHRGAIITAANPFSTPAELAKHAKASRAKLLITQACYYEKVKDFARESDVKVMCVDSAPDGCLHFSELTQADENEAPQVDISPDDVVALPYSSGTTGLPKGVMLTHKGLITSVAQQVDGDNPNLYFHSEDVILCVLPMFHIYALNSIMLCGLRVGASILIMPKFEIGSLLGLIEKYKVSIAPVVPPVMMSIAKSPDLDKHDLSSLRMIKSGGAPLGKELEDTVRAKFPQARLGQGYGMTEAGPVLAMCLAFAKEPFDIKPGACGTVVRNAEMKIVDPETGASLPRNQPGEICIRGDQIMKGYLNDPEATSRTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIAHPEISDAAVVGLKDEDAGEVPVAFVVKSEKSQATEDDIKQYISKQVIFYKRIKRVFFIEAIPKAPSGKILRKNLKEKLAGI
>rna-XM_035066388.1
MDTITKQKEEFIFRSKLPDIDIPRGLPLHSYVFENFSKYPSKPCLINGANGDIYTYSDVELTARRAASGLNKLGIQQGDVIMLILPSSPEFVLAFLGASHRGAITTAANPFSTPAELAKQAKASKAKLLITQACYYDKVKDYAQENDVKVMCVDSAPDACLHFSDLTQADGDDMPQVDISPDDVVALPYSSGTTGLPKGVMLTHRGLITSVAQQVDGDNPNLYFHREDVILCVLPMFHIYALNSIMLCGLRAGAAILIMPKFEIGSLLGLIEKYKVSIAPVVPPVMLAIAKSPDLDKHDLSSLRMLKSGGSPLGKELEDTVRAKFPQARLGQGYGMTEAGPVLAMCLAFAKEPFDIKPGACGTVVRNAEMKIVDPETGSSLPRNLPGEICIRGDQIMKGYLNDPEATSRTIDNDGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEALLQAHTGISEAAVVGMKDEDAGEIPVAFVIKSENSQVTEEEIMQYISKQVIFYKKIKRVFFVEAIPKAPSGKILRKNLRERLAGGLQK
>rna-XM_035068064.1
MEKSGYGRDGIYRSLRPKLVLPKDPNLSLVSFLFRNSNSYPHKPALIDADLSITLSFSELKSIVIKVAHGLLNLGITKNDVVLIFAPNSYQFPICFLAITSTGAIATTANPLYTTSELSKQIKDSNPKLIITVPELWDKVKGFNLPAVFLGPKRVSLPLESGSRITSFDSLVGLGGSNSQFPSSNVKQSDISTLLYSSGTTGVSKGVILTHGNFIAASLMVTMDQVTAGEMNHVFLCFLPMFHVFGLAVITYSQLQMGNAVVSMGKFEFEMVLKNIEKHRVTHMWVVPPVVLALAKQDVVKKYDLSSLRNIGSGAAPLGKDLMKECAKNMPDTIISQGYGMTETCGIVSVEDSRLGVRHSGSAGMLAAGIEAQIVSVETLKPLPPNQLGEIWVRGPNMMRGYFNNPQATKDTIDKKGWVHTGDLGYFDDDGQIFVVDRIKELIKYKGFQVAPAELEGLLVSHPQILDAVVIPYPDAEAGEVPVAYVVRSPNSALTEVDVQKFIADQVAPFKRLRKVTFINTVPKSASGKILRRELIQQVKSKI
>rna-XM_035076520.1
MEANKDQAKEFIFRSKLPDIYIANHLPLHTYCFEKLSQFKDNPCLINGPTGDIYTYADVELTSRKVASGLYRLGLQQGDVILLLLQNSPEFVFAFLGASFIGAISSTGNPFYTSAEIAKQATASKAKLIITQAAFAEKVQQFAQENDHVKIMTIDSLTDNCLHFSELTSSDENEIPAVKIKPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHERDVILCVLPLFHIYSLNSVFLCGLRAGSAILLMQKFETVALMDLVQKYKVTIAPLVPPIFLAIAKSPVVDQYDLSSIRTVLSGAAPMGKELEDTVRAKLPNAKLGQGYGMTEAGPVIAMCLAFAKEPFEVKSGACGTVVRNAEMKIVDPETGDSQPRNKAGEICIRGSQIMKGYLNDPEATERTIDKDGWLHTGDIGYIDEDELFIVDRLKELIKYKGFQVAPAELEAMLIAHPSISDAAVVPMKDEAAGEVPVAFVVRSNGSKITEDEIKQYISKQVIFYKRIGRVFFTEAIPKAPSGKILRKDLRARVSAGDIPHQIPNMQNQH
>rna-XM_035037180.1
MEAVNDQAQEFIFRSKLPDIQIPNDLPLHTYCFENLSRFKDNPCLINGPTGEIHTYTDVELTSRKVASGLSKLGIKQGDVILLLLQNSPEFVFAFLGASIIGAISTTANPFYTPSEVAKQATASKAKLIITQAVYAEKVQQFIKENDHVKLVTVDSPPENYLHFSELTNSDEDDIPAVEINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHEKDVILCVLPLFHIYSLNSVLLCGLRVGSAILLMQKFEIVTLMELVQKYKVTIAPFVPPIVLAVAKCPVVDKYDLSSIRTVMSGAAPMGKELEDTVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDTGRSLPRNQAGEICIRGSQIMKGYLNDSEATERTIDNDGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAMLIAHHDIFDCAVVPMKDEAAGEVPVAFVVRANGSKITEDEIKQFISKQVVFYKRISRVFFTESIPKAPSGKILRKDLRARLATGDLPH
>rna-XM_035042016.1
MDTITKQKEEFIFRSKLPDIDIPRGLPLHSYVFENFSKYPSKPCLINGANGDIYTYSDVELTARRAASGLNKLGIQQGDVIMLILPSSPEFVLAFLGASHRGAITTAANPFSTPAELAKQAKASKAKLLITQACYYDKVKDYAQENDVKVMCVDSAPDVCLHFSDLTQADDDDMPQVDISPDDVVALPYSSGTTGLPKGVMLTHRGLITSVAQQVDGDNPNLYFHREDVILCVLPMFHIYALNSIMLCGLRAGAAILIMPKFEIGSLLGLIEKYKVSIAPVVPPVMLAIAKSPDLDKHDLSSLRMLKSGGSPLGKELEDTVRAKFPQARLGQGYGMTEAGPVLAMCLAFAKEPFDIKPGACGTVVRNAEMKIVDPETGSSLPRNLPGEICIRGDQIMKGYLNDPEATSRTIDNDGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEALLQAHTGISEAAVVGMKDEDAGEIPVAFVIKSENSQVTEEEIMQYISKQVIFYKKIKRVFFVEAIPKAPSGKILRKNLRERLAGGLQK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University