Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Pisum sativum
Species name
Garden pea (Pisum sativum) is a species of eudicot in the family Fabaceae (pea family).
Species info
Gene sequence info
Pisum_sativum.HIDH.fa
Download
>Psat3g026920.1
MSSLPHVVEDCMGFLKLYSDGSVHRSNNFKFHVSTVQDNTVTFKDCVFDKKFNLSLRLYKPNTYNNSNNKSKLPVIVFLHGGGFCFGSRTWPHMHNCCVRLATGLQALVVAPDYRLAPEHRLPAAVDDAVEAVRWIQRQGLSLKEEENNCGEAWLRDDVDFDRVFIVGDSSGGNIAHQLAVRFGSDRTAIEPVRIRGYVLLAPFFGGEVRTKSEEGPAEQTLNLDLLDRFWRLSMPVGETSRDHPLANPFGPDSPNLEKLKFDPLLVIVGGNELLKDRAANYATRLKGMGKDIKYVEFEGCEHGFFTHDSYSEDAKKVIHILKRFMLE
>Psat3g206400.1
MTTISFNHNNQKSNNIHHQKGLIIEEIEGLIKVHKDGHVERPQIVPNISCNFAPQNGVISRDITINKQTNLWTRVYLPTSTSHNDNNKLPLLVYFHGGGFCVGSASWICYHEFLINLASKANCVVVSVNYRLAPENRLPSAYDDAFDALMWIKHEALYNKNQNWWLKHCNISSLFLCGDSAGANIAYNVVATRLASNSNSNMSSCLNLNPLILKGIILIQPFFGGEERTNSEKNLRQLQNSALSLSVSDTYWRLSLPIGVSVSRDHPYCNPLATSGISKMRDLRVPSIMICVSELDILRDRNLEFSNCLVKAGKRVETYVYKDVGHAFQVLHNYQLSHVRTQEMVSHIKNFLNQ
>Psat4g084920.1
MASTDTTKHIISEIPPYITVYNDGTIERPRQAPTVPPNLNDPNSSVSSKDIIISQNPNISARLYLPKHPTQKLPILLFFHGGGFFFESAFSKLYHEHFNIFAPQANTIVVSVEYRLAPEHPLPAAYHDCWSSLQWVASNQEPWLTNHGDLNRLFIGGDSAGGNIVHNIAMRAGSEALPNDVKLLGAILQQPFFFSSYPVGLEGVKLKSSDHDFYCSVWNFVYPSAPGGIDNCCVNPLGLEAPSLEGLGCDKMIVCVAGKDGIRERGVWYYEIVKKSGWKGKLELFEEEGEDHVYHIFYPESVNGQKLIKRLASFIHE
>Psat4g211280.1
MASSSDANKEIEKELLPLIRVYKDGTIERLMSSPMVPPSLQDPQTGVSSKDIVISNHNNPALSARIFLPKSHHKNQKLPILLYFHGGAFCVESPFSFLCHRYLNLLVSESNIIAVSVDFRLLPLHPLPAAYEDGWTSLQWVASHTSNYETNNSNLEREPWLLDYGDFNKVYIGGDVNGANLAHNLAMRAGSETLPNNLKILGALLCCPFFWGSKPIGSEPVEEHENSLAMKVWNFVYPNAKGGIDNPMVNPCAPGAPSLATLGCSKILVTITDKDEFRDRDMLYYESVKKSGWQGQLELFEAGDEEHGFQMFKPETDRAKQFLKRLASFLV
>Psat5g223920.1
MVQEKKLVDEVSGWLRIYDDGSVDRTWTGPPEVNFMIEPVAPHEEFIDGVATRDVTMSTTTNDNFIHRARLYLPEKTPTENEKLPILIHFHGGGFCITEPDCFMYYKVYTRFVKSTRSICVSPFLRRAPEHRLPAAIEDGFATLRWLQSVARGDAHDPWLEKHGDFDRVFLIGDSSGGNLVHEVSARASSTDLRPVRLAGAIPIHPGYVRSERSRSENEMPQSPFLTLDMLDKFLSLSLPIGSNKDHPITCPMGEAAPPLAGFKLPPFLLCVAEKDLLRDPQMEYYEAMRKDNKEVDLFVSKNMTHSFYLNKIAVDMDPTVSAELNALMARVKDFIEKH
>Psat5g193200.1
MNLYLINSNLPSQKKNITSSTSFKQYFLPQLIMASTTPTIPKTVTKEIITEMGTFISIFSDGSIERPIQSPFVPPVLNDPKTGHSSKDIVIPHNPAVSSRIYLPKITSPSSKFPILVYFHGGAFLFESAFSQLYHEHLKTLASQANIIIVSVEYRLAPEFPVTACYHDCWAALKWVSSHSNNTLNNPEPWLIEHGDFARVFIGGDSAGGNITHKIAIQAGTESLPCDIKILGAIMIHLYFHSSYPIGSEPIIEPQDNLFHQVWHLCYPNSPHGIDNPLVNPLGEGATSLEKLGCSRILICVAEKDKLRDRGVWYWKNVKKSGWNGKLELFEEKDENHVYHLLKPESESARKFIQRLVSFVQE
>Psat6g029400.1
MSLIAEAPEFLQVFSDGTVKRFNPETSPPSLDSSSKYLSKDIIINPSTQITGRLFLPNNPNKKLLPLLVYFHGGGFCIGSTTWLGYHAFLGEFSVASQSVILSVDYRLAPEHRLPIAYEDCYASLEWLGESVKVEPFLEHADLSNVFLSGDSAGGNISHHVAVKAIQRDGLCPVKIKGVMPIHPYFGSEKRTEKENGEEGFEDVRMNDMFWRLSLPEDSNRDYFGCNFEKNEVSESVWLKFPAVEVYVAGEDFLKERGVMYGEFLKKKGVKEVKVVEAKDERHVFHVFYPESDATRLLQNQMSQLILNNSEIFVIRNLSTNE
>Psat6g209640.1
MASSTKEISRELPPLLRVYKDGTVERFLGSPIIPPIPLDPQTGVSSKDITISQNPLISARIHLPKLTNPTQKLPILVYYHGGAFCLESAFSFLHQRYLNIIASQSNVLVVSVEYRLAPEHPLPAAYDDGWFSLKWVTSHNIIDNSIATAEPWLIKHGDFDRFYIGGDTSGANIAHNLLLRVGNSITTGVESLPGDVKIKGAILAFPLFWSSKPVLSENIEGHEESSPMKVWNFVYPDAVNGIDNPLINPLASEALGLDTIGCPKMLVFVAGNDDLRDRGIWYYDAVKESGWKGDVELVHVEGEEHCFQIYHPETKNSVDMVKRIASFLV
>Psat6g229480.1
MPTLTSNLTLIPQHGTTKNHQQHHGSSIVEEIKGLIKVHKNGYIERPNIVPCVTPDHITPNFNVISRDIIIDNVTNIWARFYVPKSQQKKLPLLVYFHGGGFCVGSAAWSCYHEFLAMLSSKLGCIIMSVNYRLAPENPLPAPYDDGVNALIWLKKQFLYQNEASTSSEFEWWTKNCNFSCVFLGGDSAGGNIAYNVARRVDSCEDAFIRPLNLKGLILIQPFFGGKERTLSEKCMVQLSGSALNLAASDAYWRLALPCGEDRDHPWCNPLVKLEELMMPVLVCISEMDILKDRNLEFCDGLGRIGKRVEYEVFEGVGHAFQILSKSQVSKIRVVQMMDRVKSFMLGLD
>Psat7g123480.1
MILSYHSCSFSLTSPLNKSYPVLPSLKLTKPLRIHCTPPQQQHQQPLSTMDDEIAIDLTPIVKVYKNGRIERLIGEEVVPASLDPTTNVESKDVIISKEDNISARLYIPKTNYPPTQKLPVFVYIHGGAFCVETPFSPNYHNYLNSVASLANVIGVSVHYRRAPEHPVPIAHEDSWLALKWVASHVGGKGSDEWLNQYADFEKVFLGGDSAGANIAHYLGIRVGKENLDDLKLEGGVFVHPYFWGVDRIGSESARGEFVEKIHTLWRFACPTTTGSDDPIINPEKDPNLGSLGFKRVLVCVAEKDLLKDRGWYYKELLEKIGWGGVVDVVETKDEHHVFHMFDPTCENAKDLLNQVVSFIKRT
>Psat7g123600.1
MDPNSTDIVREFPRLFRLYKDGRVERFLGTETTPSGTDELTAVQSKDITINTDTGIGARLYLPPNATPSQKLPLLIYIHGGAFCICTPFNPGYHHHLNNVAAQANVVVFSVHYRLAPEHPVPICYDDTWEAIQWVSQSSEPWLKDHADLNIVFLAGDSAGANIAHNMAMRGSNEGFRGLKLRGMVLVHPYFGNDEKDELIEFLYPSYGGFDDPIIHATKDPKLSSLGCGKLLVLVAEKDFLIERGRSYSEAVKKSGWSGTVEMVETEGEGHVFHLFDPRKEKSLALVKQVASFMTQVEKDVRSSSLL
>Psat7g203560.1
MSKTLVDECRGVLHVYSDGSIVRSANPAFNVPVHDDGTVLWKDVVFDSANNLKLRLYKPANSTKGSNLPVFYYIHGGGFCIGSRTWPNCQNYCFKLASQLQAVVVSPDYRLAPENRLPCAFEDGFAAVKWLQQQAVSSKPDSWLNDVADFSRVFISGDSAGGTMAHNLAVRLGFGSTELEPVRVRGYVLLAPFFGGTVRTKSEAEGPKDAFLNLELIDRFWRLSVPIGENTDHPLVNPFGPVSKRFEEIDLDPILIVVGDNDLLKDRAEEYANRLKDLGKNIEYVEFEGQQHGFFTFDPNSEPSKELMLVIKGFIDKY
>Psat7g123520.1
MVESKDVIISKEDNISARLYIPKTNYPPTQKLPVFVYIHGGAFCIETPASPNYHNYLNSVTSLANVIGVSVHYRRAPEHPVPVAHEDSWLALKWVASHVGGKGSDEWLNKFADFEKVLLGGDSAGANIAHYLGIRAGKENLGGVKLEGGVYLHPYFWGVDPIGSESARGEFVEKVHNLWRFSCPTTTGSDDPLINPEKDPNLGSLGFKRVLVCVAEKDLLKDRGWYYKELLDKIGWGGVVEVVETKDEDHVFHMFNPTCENAKDLLNRVVSFINKA
>Psat0s1109g0040.1
MDPQISIDVPPYLRVHKNGTVERLVGIDVAPPGIDPQTNVISKDITILPKTGVTARLYSPTKTSTKLPLILYLHGGAYCISSPSDPLYHNSLNNLVAEANIIAISVNYRLAPEHPLPIAYDDSWEALQWVASHAVEDGFDGFNGFNGQEKENWIKEKVDFNRVFLAGDSAGANMGHYMCLKDHNFVNFKILGLIMVNPYFWGKEPIGVEISDSERKKMVDKWWEFVCPSDKGSDDPLINPFVEEAPGIEGLCVEKVLVTVAEKDILRERGKLYHKKLVNSSWKGTAEFYETQEEDHVFHIFNPDCAKAKSLIKRIAVFINE
MSSLPHVVEDCMGFLKLYSDGSVHRSNNFKFHVSTVQDNTVTFKDCVFDKKFNLSLRLYKPNTYNNSNNKSKLPVIVFLHGGGFCFGSRTWPHMHNCCVRLATGLQALVVAPDYRLAPEHRLPAAVDDAVEAVRWIQRQGLSLKEEENNCGEAWLRDDVDFDRVFIVGDSSGGNIAHQLAVRFGSDRTAIEPVRIRGYVLLAPFFGGEVRTKSEEGPAEQTLNLDLLDRFWRLSMPVGETSRDHPLANPFGPDSPNLEKLKFDPLLVIVGGNELLKDRAANYATRLKGMGKDIKYVEFEGCEHGFFTHDSYSEDAKKVIHILKRFMLE
>Psat3g206400.1
MTTISFNHNNQKSNNIHHQKGLIIEEIEGLIKVHKDGHVERPQIVPNISCNFAPQNGVISRDITINKQTNLWTRVYLPTSTSHNDNNKLPLLVYFHGGGFCVGSASWICYHEFLINLASKANCVVVSVNYRLAPENRLPSAYDDAFDALMWIKHEALYNKNQNWWLKHCNISSLFLCGDSAGANIAYNVVATRLASNSNSNMSSCLNLNPLILKGIILIQPFFGGEERTNSEKNLRQLQNSALSLSVSDTYWRLSLPIGVSVSRDHPYCNPLATSGISKMRDLRVPSIMICVSELDILRDRNLEFSNCLVKAGKRVETYVYKDVGHAFQVLHNYQLSHVRTQEMVSHIKNFLNQ
>Psat4g084920.1
MASTDTTKHIISEIPPYITVYNDGTIERPRQAPTVPPNLNDPNSSVSSKDIIISQNPNISARLYLPKHPTQKLPILLFFHGGGFFFESAFSKLYHEHFNIFAPQANTIVVSVEYRLAPEHPLPAAYHDCWSSLQWVASNQEPWLTNHGDLNRLFIGGDSAGGNIVHNIAMRAGSEALPNDVKLLGAILQQPFFFSSYPVGLEGVKLKSSDHDFYCSVWNFVYPSAPGGIDNCCVNPLGLEAPSLEGLGCDKMIVCVAGKDGIRERGVWYYEIVKKSGWKGKLELFEEEGEDHVYHIFYPESVNGQKLIKRLASFIHE
>Psat4g211280.1
MASSSDANKEIEKELLPLIRVYKDGTIERLMSSPMVPPSLQDPQTGVSSKDIVISNHNNPALSARIFLPKSHHKNQKLPILLYFHGGAFCVESPFSFLCHRYLNLLVSESNIIAVSVDFRLLPLHPLPAAYEDGWTSLQWVASHTSNYETNNSNLEREPWLLDYGDFNKVYIGGDVNGANLAHNLAMRAGSETLPNNLKILGALLCCPFFWGSKPIGSEPVEEHENSLAMKVWNFVYPNAKGGIDNPMVNPCAPGAPSLATLGCSKILVTITDKDEFRDRDMLYYESVKKSGWQGQLELFEAGDEEHGFQMFKPETDRAKQFLKRLASFLV
>Psat5g223920.1
MVQEKKLVDEVSGWLRIYDDGSVDRTWTGPPEVNFMIEPVAPHEEFIDGVATRDVTMSTTTNDNFIHRARLYLPEKTPTENEKLPILIHFHGGGFCITEPDCFMYYKVYTRFVKSTRSICVSPFLRRAPEHRLPAAIEDGFATLRWLQSVARGDAHDPWLEKHGDFDRVFLIGDSSGGNLVHEVSARASSTDLRPVRLAGAIPIHPGYVRSERSRSENEMPQSPFLTLDMLDKFLSLSLPIGSNKDHPITCPMGEAAPPLAGFKLPPFLLCVAEKDLLRDPQMEYYEAMRKDNKEVDLFVSKNMTHSFYLNKIAVDMDPTVSAELNALMARVKDFIEKH
>Psat5g193200.1
MNLYLINSNLPSQKKNITSSTSFKQYFLPQLIMASTTPTIPKTVTKEIITEMGTFISIFSDGSIERPIQSPFVPPVLNDPKTGHSSKDIVIPHNPAVSSRIYLPKITSPSSKFPILVYFHGGAFLFESAFSQLYHEHLKTLASQANIIIVSVEYRLAPEFPVTACYHDCWAALKWVSSHSNNTLNNPEPWLIEHGDFARVFIGGDSAGGNITHKIAIQAGTESLPCDIKILGAIMIHLYFHSSYPIGSEPIIEPQDNLFHQVWHLCYPNSPHGIDNPLVNPLGEGATSLEKLGCSRILICVAEKDKLRDRGVWYWKNVKKSGWNGKLELFEEKDENHVYHLLKPESESARKFIQRLVSFVQE
>Psat6g029400.1
MSLIAEAPEFLQVFSDGTVKRFNPETSPPSLDSSSKYLSKDIIINPSTQITGRLFLPNNPNKKLLPLLVYFHGGGFCIGSTTWLGYHAFLGEFSVASQSVILSVDYRLAPEHRLPIAYEDCYASLEWLGESVKVEPFLEHADLSNVFLSGDSAGGNISHHVAVKAIQRDGLCPVKIKGVMPIHPYFGSEKRTEKENGEEGFEDVRMNDMFWRLSLPEDSNRDYFGCNFEKNEVSESVWLKFPAVEVYVAGEDFLKERGVMYGEFLKKKGVKEVKVVEAKDERHVFHVFYPESDATRLLQNQMSQLILNNSEIFVIRNLSTNE
>Psat6g209640.1
MASSTKEISRELPPLLRVYKDGTVERFLGSPIIPPIPLDPQTGVSSKDITISQNPLISARIHLPKLTNPTQKLPILVYYHGGAFCLESAFSFLHQRYLNIIASQSNVLVVSVEYRLAPEHPLPAAYDDGWFSLKWVTSHNIIDNSIATAEPWLIKHGDFDRFYIGGDTSGANIAHNLLLRVGNSITTGVESLPGDVKIKGAILAFPLFWSSKPVLSENIEGHEESSPMKVWNFVYPDAVNGIDNPLINPLASEALGLDTIGCPKMLVFVAGNDDLRDRGIWYYDAVKESGWKGDVELVHVEGEEHCFQIYHPETKNSVDMVKRIASFLV
>Psat6g229480.1
MPTLTSNLTLIPQHGTTKNHQQHHGSSIVEEIKGLIKVHKNGYIERPNIVPCVTPDHITPNFNVISRDIIIDNVTNIWARFYVPKSQQKKLPLLVYFHGGGFCVGSAAWSCYHEFLAMLSSKLGCIIMSVNYRLAPENPLPAPYDDGVNALIWLKKQFLYQNEASTSSEFEWWTKNCNFSCVFLGGDSAGGNIAYNVARRVDSCEDAFIRPLNLKGLILIQPFFGGKERTLSEKCMVQLSGSALNLAASDAYWRLALPCGEDRDHPWCNPLVKLEELMMPVLVCISEMDILKDRNLEFCDGLGRIGKRVEYEVFEGVGHAFQILSKSQVSKIRVVQMMDRVKSFMLGLD
>Psat7g123480.1
MILSYHSCSFSLTSPLNKSYPVLPSLKLTKPLRIHCTPPQQQHQQPLSTMDDEIAIDLTPIVKVYKNGRIERLIGEEVVPASLDPTTNVESKDVIISKEDNISARLYIPKTNYPPTQKLPVFVYIHGGAFCVETPFSPNYHNYLNSVASLANVIGVSVHYRRAPEHPVPIAHEDSWLALKWVASHVGGKGSDEWLNQYADFEKVFLGGDSAGANIAHYLGIRVGKENLDDLKLEGGVFVHPYFWGVDRIGSESARGEFVEKIHTLWRFACPTTTGSDDPIINPEKDPNLGSLGFKRVLVCVAEKDLLKDRGWYYKELLEKIGWGGVVDVVETKDEHHVFHMFDPTCENAKDLLNQVVSFIKRT
>Psat7g123600.1
MDPNSTDIVREFPRLFRLYKDGRVERFLGTETTPSGTDELTAVQSKDITINTDTGIGARLYLPPNATPSQKLPLLIYIHGGAFCICTPFNPGYHHHLNNVAAQANVVVFSVHYRLAPEHPVPICYDDTWEAIQWVSQSSEPWLKDHADLNIVFLAGDSAGANIAHNMAMRGSNEGFRGLKLRGMVLVHPYFGNDEKDELIEFLYPSYGGFDDPIIHATKDPKLSSLGCGKLLVLVAEKDFLIERGRSYSEAVKKSGWSGTVEMVETEGEGHVFHLFDPRKEKSLALVKQVASFMTQVEKDVRSSSLL
>Psat7g203560.1
MSKTLVDECRGVLHVYSDGSIVRSANPAFNVPVHDDGTVLWKDVVFDSANNLKLRLYKPANSTKGSNLPVFYYIHGGGFCIGSRTWPNCQNYCFKLASQLQAVVVSPDYRLAPENRLPCAFEDGFAAVKWLQQQAVSSKPDSWLNDVADFSRVFISGDSAGGTMAHNLAVRLGFGSTELEPVRVRGYVLLAPFFGGTVRTKSEAEGPKDAFLNLELIDRFWRLSVPIGENTDHPLVNPFGPVSKRFEEIDLDPILIVVGDNDLLKDRAEEYANRLKDLGKNIEYVEFEGQQHGFFTFDPNSEPSKELMLVIKGFIDKY
>Psat7g123520.1
MVESKDVIISKEDNISARLYIPKTNYPPTQKLPVFVYIHGGAFCIETPASPNYHNYLNSVTSLANVIGVSVHYRRAPEHPVPVAHEDSWLALKWVASHVGGKGSDEWLNKFADFEKVLLGGDSAGANIAHYLGIRAGKENLGGVKLEGGVYLHPYFWGVDPIGSESARGEFVEKVHNLWRFSCPTTTGSDDPLINPEKDPNLGSLGFKRVLVCVAEKDLLKDRGWYYKELLDKIGWGGVVEVVETKDEDHVFHMFNPTCENAKDLLNRVVSFINKA
>Psat0s1109g0040.1
MDPQISIDVPPYLRVHKNGTVERLVGIDVAPPGIDPQTNVISKDITILPKTGVTARLYSPTKTSTKLPLILYLHGGAYCISSPSDPLYHNSLNNLVAEANIIAISVNYRLAPEHPLPIAYDDSWEALQWVASHAVEDGFDGFNGFNGQEKENWIKEKVDFNRVFLAGDSAGANMGHYMCLKDHNFVNFKILGLIMVNPYFWGKEPIGVEISDSERKKMVDKWWEFVCPSDKGSDDPLINPFVEEAPGIEGLCVEKVLVTVAEKDILRERGKLYHKKLVNSSWKGTAEFYETQEEDHVFHIFNPDCAKAKSLIKRIAVFINE
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University